Abstract:
OBJECTIVE:To assess the diagnostic performance of quantitative and qualitative image parameters in cone-beam computed tomography (CBCT) for diagnosis of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS:A BRONJ (22 patients, mean age 70.0 years) group was age and gender matched to a healthy control group (22 patients, mean age 68.0 years). On CBCT images two independent readers performed quantitative bone density value (BDV) measurements with region and volume-of-interest (ROI and VOI) based approaches and qualitative scoring of BRONJ-associated necrosis, sclerosis and periosteal thickening (1 = not present to 5 = definitely present). Intraoperative and clinical findings served as standard of reference. Interreader agreements and diagnostic performance were assessed by intraclass correlation coefficients (ICC), kappa-statistics and receiver-operating characteristic (ROC) analysis. RESULTS:Twenty-three regions in 22 patients were affected by BRONJ. ICC values for mean BDV VOI and mean BDV ROI were 0.864 and 0.968, respectively (p < 0.001). The area under the curve (AUC) for mean BDV VOI and mean BDV ROI was 0.58/0.83 with a sensitivity of 57/83% and specificity of 61/77% for diagnosis of BRONJ, respectively. Kappa values for presence of necrosis, sclerosis and periosteal thickening were 0.575, 0.617 and 0.885, respectively. AUC values for qualitative parameters ranged between 0.90-0.96 with sensitivity of 96% and specificities between 79-96% at respective cutoff scores. CONCLUSIONS:BRONJ can be effectively diagnosed with CBCT. Qualitative image parameters yield a higher diagnostic performance than quantitative parameters, and ROI-based attenuation measurements were more accurate than VOI-based measurements.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Guggenberger R,Koral E,Zemann W,Jacobsen C,Andreisek G,Metzler Pdoi
10.1007/s00256-014-1951-1subject
Has Abstractpub_date
2014-12-01 00:00:00pages
1669-78issue
12eissn
0364-2348issn
1432-2161journal_volume
43pub_type
杂志文章abstract:DESIGN AND PATIENTS:We reviewed the MR appearances of six cases of longitudinal stress fracture of the lower extremity. RESULTS:One fracture was in the femur and five were in the tibia. Four of the tibial fractures showed edema starting in the mid-tibia at the level of the nutrient foramen with the fracture on the ant...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0597-6
更新日期:2003-01-01 00:00:00
abstract::Two children presented with painful lytic lesions in the lower extremity. The lesions were located within cortical bone, and surrounded by sclerosis of the medullary bone and periosteal new bone formation. The lesions were painful, and nonsteroidal anti-inflammatory agents relieved the pain. CT-guided core biopsies we...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0501-4
更新日期:2002-10-01 00:00:00
abstract::Scoliosis is defined as a lateral deviation of the spine from the normal plumb line. Commonly, there is a rotational component and deviation also in the sagittal plane (kyphosis or hyperlordosis). When scoliosis presents in adults, it is often painful. In contrast, back pain in a child is considered rare, and serious ...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-008-0517-5
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:Metal-on-metal hip resurfacing arthroplasty (MoMHRA) has become a popular option for young patients requiring hip replacement. A recognised complication is the formation of a symptomatic reactive periprosthetic soft tissue mass (pseudotumour). We present a radiological classification system for these reactive...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1329-6
更新日期:2012-02-01 00:00:00
abstract:: ...
journal_title:Skeletal radiology
pub_type:
doi:10.1007/s00256-018-2997-2
更新日期:2018-12-01 00:00:00
abstract::Acute megakaryoblastic leukemia or acute "malignant" myelosclerosis is an acute and rapidly progressive myeloproliferative syndrome characterized by minimal or absent splenomegaly, pancytopenia, diffuse marrow fibrosis, and circulating blasts of megakaryocytic origin. The disease must be differentiated from other hema...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00367381
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of bone islands in leprosy patients. DESIGN:X-rays of feet and hands of patients with Hansen's disease (leprosy) were reviewed retrospectively. A second group of related age- and sex-matched patients who did not have Hansen's disease was used for control purposes. Controls had unde...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050391
更新日期:1998-06-01 00:00:00
abstract::A complete slip of the cartilage of the inferior angle of the scapula was diagnosed in a 5-year-old boy who fell inside a wooden construction at a kindergarten playground. Radiographs of the scapula were normal, and ultrasound demonstrated complete cartilage detachment, which was displaced deep and laterally. Computed...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1311-3
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To determine the ultrasonographic changes after steroid injection in carpal tunnel syndrome (CTS) and to evaluate the diagnostic value of ultrasound in post-treatment examination with clinical correlation. MATERIALS AND METHODS:Twenty-seven wrists with idiopathic CTS after a single injection of 40 mg of pred...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2738-y
更新日期:2017-11-01 00:00:00
abstract::Four cases of osteoid osteomas are presented. An uncharacteristic magnetic resonance finding of soft tissue edema is reported. This observation should not be misinterpreted as indicating a more aggressive pathologic process and, thereby, exclude osteoid osteoma from the differential. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00191523
更新日期:1993-01-01 00:00:00
abstract::The trapeziometacarpal joint is particularly prone to osteoarthritis due to the great amount of stress applied with everyday activities with the hands. In this essay, radiologic assessment and staging of "basal joint" osteoarthritis, treatments based on radiologic staging and intraoperative findings, and surgical comp...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00202151
更新日期:1995-10-01 00:00:00
abstract::Liposarcoma is a relatively common soft tissue malignancy with a wide spectrum of clinical presentations and imaging appearances. Several subtypes are described, ranging from lesions nearly entirely composed of mature adipose tissue, to tumors with very sparse adipose elements. The imaging appearance of these fatty ma...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-003-0647-8
更新日期:2003-09-01 00:00:00
abstract::Behcet's disease is a chronic inflammatory condition involving several organs, such as the skin, mucous membranes, eyes, joints, intestines, lungs and central nervous system. It rarely affects the spinal column. We describe a case of progressive atlanto-axial subluxation in a 44-year-old woman with Behcet's disease. T...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0815-6
更新日期:2010-03-01 00:00:00
abstract::Aneurysms of the distal radial artery at the level of the wrist are rare. Most reported cases are posttraumatic, either from iatrogenic arterial puncture for radial arterial access or from a penetrating injury. Other causes include infection and connective tissue disorders. Early diagnosis is important to avoid the po...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-018-3061-y
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:Burnout is a job-related psychological syndrome with three aspects: emotional exhaustion, depersonalization, and perceived lack of personal accomplishment. Burnout is associated with deleterious effects on both workers and their work. When burnout affects physicians, their well-being, longevity, and care of p...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2578-9
更新日期:2017-04-01 00:00:00
abstract::In a collection of 101 anatomical preparations of the human pelvis, ossification of the sacrotuberous ligament was found in 8 cases. In 7 of these, the ossification showed a characteristic intraligamentous morphology, with a broad-based origin at the ischial tuberosity and tapering off craniomedially. The length varie...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00197139
更新日期:1993-11-01 00:00:00
abstract::Lipomatosis of nerve is a rare benign tumor-like process characterized by infiltration of the epineurium by adipose and fibrous tissue leading to nerve enlargement. We describe a case of lipomatosis of the sciatic nerve compressed by an adjacent desmoid tumor. This case supports the hypothesis that lipomatosis of nerv...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-013-1671-y
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To report 12 cases of chondrosarcoma in a rare location, the short tubular bones of the hands and feet, as well as 12 cases of enchondroma in similar locations, emphasizing the radiologic and histopathologic features. DESIGN AND PATIENTS:All relevant cases that had both histologic slides and radiographs avai...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050448
更新日期:1998-11-01 00:00:00
abstract::Shoulder arthroplasty is performed with increasing frequency, and osteoarthritis is the most common indication for this procedure. However, the glenoid side of the joint is widely recognized as a limiting factor in the long-term durability of shoulder replacement, and osteoarthritis leads to characteristic bony change...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-020-03647-x
更新日期:2020-10-23 00:00:00
abstract:PURPOSE:The purpose of this nested case-control study was to identify baseline, incident, and progressive MRI findings visible on standard MRI clinical sequences that were associated with development of incident knee pain in subjects at risk for OA over a period of 48 months. METHODS:We analyzed 60 case knees developi...
journal_title:Skeletal radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00256-016-2343-5
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To delineate the spectrum of knee injuries associated with sprains and tears of the distal iliotibial band (ITB). MATERIALS AND METHODS:A retrospective review of 200 random MRI scans undertaken for acute knee trauma was performed. Scans were excluded if there was a history of injury over 4 weeks from the tim...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-014-1918-2
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To compare polytomography (PT) and computed tomography (CT) for visualizing fractures and arthrodeses, with and without metal hardware, to determine whether CT could adequately replace PT. DESIGN AND PATIENTS:An ex vivo bovine model containing fractures in three planes, reduced with metal hardware, was creat...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050526
更新日期:1999-06-01 00:00:00
abstract::Femoroacetabular impingement syndrome (FAI) is a pathologic entity which can lead to chronic symptoms of pain, reduced range of motion in flexion and internal rotation, and has been shown to correlate with degenerative arthritis of the hip. History, physical examination, and supportive radiographic findings such as ev...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-005-0932-9
更新日期:2005-11-01 00:00:00
abstract::Luxatio erecta or inferior dislocation of the shoulder joint is rare and is caused by a hyperabduction injury. The clinical appearance is characteristic, with the arm locked in an elevated position. Radiographically, the shaft of the humerus is directed upwards and the humeral head lies inferior to the glenoid fossa, ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361132
更新日期:1984-01-01 00:00:00
abstract::The authors present a case report and review of the sparse literature of a rare closed degloving injury to the toe, referred to by Flaherty as an "empty toe phenomenon." A 25-year-old man sustained a twisting injury to his left foot when he was involved in a motorcycle accident. The skin was not lacerated around the t...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-013-1690-8
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:There are no published large-scale studies of the overall prevalence of diffuse idiopathic skeletal hyperostosis (DISH) and it has been proposed that the prevalence is greater than previously reported. We thus decided to review chest radiographs in a population of patients over 50 years of age seen at two lar...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050225
更新日期:1997-04-01 00:00:00
abstract::Hip resurfacing arthroplasty is an increasingly common procedure for osteoarthritis. Conventional radiographs are used routinely for follow-up assessment, however they only provide limited information on the radiological outcome. Various complications have been reported in the scientific literature although not all ar...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-010-1081-3
更新日期:2011-07-01 00:00:00
abstract::A 39-year-old man with acromegaly exhibited locking of metacarpophalangeal (MCP) joints of both index fingers. Large osteophytes were found at the metacarpal heads by radiography and computerized tomography (CT). Magnetic resonance (MR) images revealed hypertrophy of volar plates. We suggest that these characteristic ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050569
更新日期:1999-11-01 00:00:00
abstract::We report a unique case of mediastinal paravertebral chordoma without bone destruction in a 47-year-old Japanese woman. She was admitted to hospital after a tumor was incidentally detected on a chest radiograph. The tumor was located in the paravertebral region of the mediastinum and did not show any destruction of th...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-012-1493-3
更新日期:2012-12-01 00:00:00
abstract::We report two cases of subchondral insufficiency fracture of the femoral head observed in younger adults without any history of overexertion. In both cases, MRI revealed an irregular, discontinuous low-intensity band on the T1-weighted images. Both patients were treated operatively, and histological examination confir...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-006-0178-1
更新日期:2007-06-01 00:00:00