Abstract：
BACKGROUND:The clinical importance of papillary thyroid microcarcinoma (PTMC) remains controversial, with current guidelines suggesting that thyroid lobectomy alone is sufficient. The purpose of this study was to identify population-level treatment patterns in the USA for PTMC. METHODS:Patients with PTMC in SEER (1998-2010) were included; demographic, clinical (extent of surgery, administration of post-operative radioactive iodine [RAI]), and pathologic characteristics were examined. Outcomes of interest were 5- and 10-year overall survival (OS) and disease-specific survival (DSS). RESULTS:The cohort consisted of 29,512 patients. Mean age at diagnosis was 48.5 years; mean tumor size was 0.53 cm. Overall, 73.4 % of patients underwent total thyroidectomy, and RAI was administered to 31.3 %. In multivariate analysis, total thyroidectomy was more frequently performed in patients with multifocal (odds ratio [OR] 2.55), 'regional', or 'distant' PTMC (OR 2.90 and 2.59). Non-operative management was associated with male patients (OR 4.24) and those aged ≥65 years (OR 6.31). Post-operative RAI was associated with multifocal PTMC (OR 2.57). Overall, 5- and 10-year DSS was 99.6 and 99.3 %, respectively, with no difference in DSS between patients who underwent partial versus total thyroidectomy. OS of patients with PTMC who underwent any thyroid operation was similar to that of the general population of the USA. CONCLUSIONS:An increasing number of patients are undergoing total thyroidectomy and RAI for PTMC. While there may be a subset of patients for whom more aggressive therapy is indicated, many patients with PTMC may be over-treated, with no demonstrable benefit to survival.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Wang TS,Goffredo P,Sosa JA,Roman SAdoi
10.1007/s00268-014-2602-3subject
Has Abstractpub_date
2014-09-01 00:00:00pages
2297-303issue
9eissn
0364-2313issn
1432-2323journal_volume
38pub_type
杂志文章abstract：INTRODUCTION:Thyroid cancer (TC) incidence has been increasing in recent years. The aim of this study was to investigate our institution-based estimates of operative volumes for TC over the last three decades. MATERIALS AND METHODS:This was a retrospective cohort study of patients undergoing thyroid surgery at our ins...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3322-z
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Never events (NEs) are serious clinical incidents that cause potentially avoidable harm and impose a significant financial burden on healthcare systems. The purpose of this study was to identify common never events. METHODS:We analysed the NHS England NE data from 2012 to 2020 to identify common never event...
journal_title：World journal of surgery
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更新日期：2021-03-01 00:00:00
abstract：BACKGROUND:The new global epidemic, overweight and obesity, has a significant role in the etiology of liver tumors. However, the impact of body weight on the outcome after liver resection is unknown. METHODS:We carried out a prospective study of 684 patients who underwent liver resections. Patients were stratified acc...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0756-1
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Alternative methods to overcome limitations of electromyogram (EMG) tube applied for intraoperative neuromonitoring (IONM) of recurrent laryngeal nerve (RLN) during thyroidectomy have been introduced. In this study, we evaluated the feasibility of adhesive skin electrodes for IONM of RLN in patients who unde...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05208-3
更新日期：2020-01-01 00:00:00
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journal_title：World journal of surgery
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abstract：:The eponym "Graves' disease" is usually applied to the condition of immunogenic hyperthyroidism, in no small part due to the promotion and influence of the French physician Armand Trousseau who wrote in 1862, "Du Goître Exophthalmique, ou Maladie de Graves." However, the distinguished Bath physician Caleb Hillier Parr...
journal_title：World journal of surgery
pub_type： 传,历史文章,杂志文章
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更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:Postoperative pancreatic fistula (POPF) is a major complication and main cause of mortality after pancreaticoduodenectomy (PD). Afferent loop decompression technique (ALDT) has theoretical feasibility to reduce the rate of POPF. The aim of this study is to determine whether ALDT is a protective factor for PO...
journal_title：World journal of surgery
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更新日期：2018-11-01 00:00:00
abstract：:Pepsinogen C is a proteolytic enzyme involved in the digestion of proteins in the stomach; it is also synthesized by a significant percentage of female breast carcinomas. In addition, it has been demonstrated that pepsinogen C is one of the few proteins induced by androgens in breast carcinoma cells. Here we evaluate ...
journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：1999-05-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2008-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2011-12-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900217
更新日期：1997-02-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900347
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:The treatment of acute limb ischemia (ALI) has barely changed over the last years. However, the progressive implementation of anticoagulants, antiplatelet agents or statins within the population might have modified the profile and prognosis of patients suffering an ALI. The aim of this study was to evaluate ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4511-3
更新日期：2018-08-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02067118
更新日期：1992-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-014-2690-0
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Segmentectomy for radiologically pure solid tumors is still controversial because these tumors are more aggressive in malignancy than those with ground-glass opacity. This study aimed to determine the feasibility of intentional segmentectomy for pure solid small-sized lung cancer. METHODS:We retrospectively...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4514-0
更新日期：2018-08-01 00:00:00
abstract：:Endocrine surgeons have had an important role in the management of hyperthyroidism due to either Graves' disease or toxic nodule(s). Since alternative treatments such as antithyroid drugs or radioiodine are also available, the decision-making for management should be based on clear assessment of advantages and limitat...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
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更新日期：2000-08-01 00:00:00
abstract：BACKGROUND:Existing data suggest a large burden of surgical conditions in low- and middle-income countries (LMICs). However, surgical care for children in LMICs remains poorly understood. Our goal was to define the hospital infrastructure, workforce, and delivery of surgical care for children across Somaliland and prov...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05079-8
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Schistosomiasis is a waterborne trematode with numerous subtypes affecting different areas of the body. Rob Ferreira Hospital is located in an endemic area for schistosomiasis in the Lowveld region of South Africa. We set out to determine the prevalence of Sch istosoma in appendicitis. METHODS:From 2009 to ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2954-3
更新日期：2015-05-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2005-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7205-y
更新日期：2004-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4658-y
更新日期：2018-11-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4833-1
更新日期：2019-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05199-1
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:The present study was designed to evaluate the relationship between preoperative Toll-like receptor (TLR) expression in peripheral blood monocytes (PBMC) and the postoperative inflammatory cytokine secretion from PBMC, as well as the postoperative infectious complications in patients with gastrointestinal ca...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0839-z
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Stapled anopexia was introduced as a surgical method in 1993. Long-term data with special interest in functional results and relapse symptoms are rarely presented. Urinary discomfort and problems with fecal urge incontinence are addressed as severe side effects. We present our long-term results (using data f...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9818-z
更新日期：2009-02-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0910-9
更新日期：2011-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9697-3
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:This study was designed to asses the predictive factors of postoperative complications in patients who underwent a laparoscopic elective approach for recurrent diverticulitis and to determine the relationship between the number of acute episodes and surgical morbidity. METHODS:A retrospective analysis was p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0162-8
更新日期：2009-11-01 00:00:00
