Abstract:
OBJECTIVE:The aim of this study was to evaluate the correlations between T2 value, T2* value, and histological grades of degenerated human articular cartilage. MATERIALS AND METHODS:T2 mapping and T2* mapping of nine tibial osteochondral specimens were obtained using a 3-T MRI after total knee arthroplasty. A total of 94 ROIs were analyzed. Histological grades were assessed using the David-Vaudey scale. Spearman's rho correlation analysis and Pearson's correlation analysis were performed. RESULTS:The mean relaxation values in T2 map with different histological grades (0, 1, 2) of the cartilage were 51.9 ± 9.2 ms, 55.8 ± 12.8 ms, and 59.6 ± 10.2 ms, respectively. The mean relaxation values in T2* map with different histological grades (0, 1, 2) of the cartilage were 20.3 ± 10.3 ms, 21.1 ± 12.4 ms, and 15.4 ± 8.5 ms, respectively. Spearman's rho correlation analysis confirmed a positive correlation between T2 value and histological grade (ρ = 0.313, p < 0.05). Pearson's correlation analysis revealed a significant negative correlation between T2 and T2* (r = -0.322, p < 0.05). Although T2* values showed a decreasing trend with an increase in cartilage degeneration, this correlation was not statistically significant in this study (ρ = -0.192, p = 0.129). CONCLUSIONS:T2 mapping was correlated with histological degeneration, and it may be a good biomarker for osteoarthritis in human articular cartilage. However, the strength of the correlation was weak (ρ = 0.313). Although T2* values showed a decreasing trend with an increase in cartilage degeneration, the correlation was not statistically significant. Therefore, T2 mapping may be more appropriate for the initial diagnosis of articular cartilage degeneration in the knee joint. Further studies on T2* mapping are needed to confirm its reliability and mechanism in cartilage degeneration.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Kim T,Min BH,Yoon SH,Kim H,Park S,Lee HY,Kwack KSdoi
10.1007/s00256-014-1872-zsubject
Has Abstractpub_date
2014-07-01 00:00:00pages
947-54issue
7eissn
0364-2348issn
1432-2161journal_volume
43pub_type
杂志文章,评审abstract::Axial magnetic resonance (MR) imaging of the patellofemoral compartment was performed in 75 patients with arthroscopic correlation. Proton density and T2(2500/20/80) weighted images were obtained in all patients. Chondromalacia in stages I and II could not be reliably identified with MR imaging. For the evaluation of ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00198391
更新日期:1993-01-01 00:00:00
abstract::A tear at the origin of the deltoid muscle is uncommon and usually occurs as a complication of shoulder surgery. We report a case of spontaneous deltoid detachment as a complication of massive rotator cuff tear in a 70-year-old woman evaluated by standard radiographs, ultrasound, arthrography and MR-arthrography. We p...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-005-0046-4
更新日期:2006-06-01 00:00:00
abstract::Shoulder magnetic resonance (MR) imaging and MR arthrography are frequently utilized in the evaluation of shoulder pain and instability. The clinical scenario and imaging findings may be confusing to clinicians and radiologists and may present diagnostic challenges for those involved in evaluating and treating shoulde...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-002-0528-6
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to describe the sonographic findings of pathologically confirmed subcutaneous lobular capillary hemangioma of the finger in six patients. MATERIALS AND METHODS:The clinical records were reviewed for data, including the patients' age and gender, the clinical presentation, a histo...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-010-0934-0
更新日期:2010-11-01 00:00:00
abstract::This article highlights the key aspects and current perspectives of the role of cross-sectional imaging in adult crystal and inflammatory arthropathies in adults, briefly discussing CT, and particularly focusing on MRI and US imaging as it supplements the conventional radiography. The role of conventional and advanced...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-016-2402-y
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To establish a novel method of quantifying meniscal deformation using loaded MRI. More specifically, the goals were to evaluate the (1) accuracy, (2) inter-rater reliability, (3) intra-rater reliability, and (4) scan-rescan reliability. The secondary purpose of this experiment was to evaluate group difference...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-014-2022-3
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To compare knee MRI performed with the integrated parallel acquisition technique (PAT) and simultaneous multislice (SMS) turbo spin echo (TSE) T2-weighted (T2w) sequences with conventional TSE sequences in pediatric patients. MATERIALS AND METHODS:This was a retrospective IRB-approved study. Seventy-four subje...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2868-2
更新日期:2018-06-01 00:00:00
abstract::Pseudotumours are well recognised as a complication of metal-on-metal hip arthroplasties and are thought to develop on the basis of an innate and adaptive immune response to cobalt-chrome (Co-Cr) wear particles. We report a case of a large pseudotumour that developed following a knee endoprosthetic replacement (EPR) u...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2610-0
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to clarify the efficacy of stress radiography (stress X-P), ultrasonography (US), and magnetic resonance (MR) imaging in the detection of the anterior talofibular ligament (ATFL) injury. METHODS:Thirty-four patients with ankle sprain were involved. In all patients, Stress X-P, U...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0767-x
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate sequences that are established at lower magnetic field strengths for lumbar spine imaging at 7 Tesla (7 T) MR imaging. MATERIALS AND METHODS:The lumbar spine of five healthy volunteers and a patient with spina bifida and meningocele were evaluated at 7 T. The examination...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1197-0
更新日期:2012-05-01 00:00:00
abstract::Intraosseous gout involving the patella is an unusual presentation of the common inflammatory crystal deposition disease. In most reported cases of gout in the patella, there is prominent involvement of the adjacent patellar or quadriceps tendons of the extensor mechanism. A report from Japan describes another pattern...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-020-03422-y
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:This study aims to quantitatively characterize the distribution of subchondral bone density across the human femoral head using a computed tomography derived measurement of bone density and a common reference coordinate system. MATERIALS AND METHODS:Femoral head surfaces were created bilaterally for 30 patie...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1270-8
更新日期:2012-06-01 00:00:00
abstract::Computed tomography is increasingly utilized for the evaluation of scaphoid fracture, nonunion, and deformity. We have developed a new technique of positioning patients while performing longitudinal computed tomography of the scaphoid. With the wrist positioned in radial deviation and neutral flexion, greater patient ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00198413
更新日期:1995-05-01 00:00:00
abstract::A thrombosed, leaking aneurysm of the popliteal artery, mimicking a soft tissue sarcoma both clinically and by MRI examination, is described. It may be difficult to separate a leaking, thrombosed aneurysm from an inflammatory response secondary to a sarcoma with intralesional hemorrhage. An aneurysm should, however, b...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00243728
更新日期:1991-01-01 00:00:00
abstract::Benign fibrous histiocytoma is an extremely rare spinal tumor with ten reported cases in the literature. Benign fibrous histiocytoma constitutes a diagnostic challenge because it shares common clinical symptoms, radiological characteristics, and histological features with other benign lesions involving the spine. We p...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-008-0597-2
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of radiation dose reduction on image quality in patients with metal-on-metal total hip arthroplasties (THAs) using model-based iterative reconstruction (MBIR) combined with orthopaedic metal artefact reduction (O-MAR). MATERIALS AND METHODS:Patients with metal-on-metal THAs received a ...
journal_title:Skeletal radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00256-019-03206-z
更新日期:2019-11-01 00:00:00
abstract::The relationship of the posterior aspects of the atlas and the axis were studied in 100 normal adult volunteers. The ratio of the height of the atlantal spinolaminar line to the atlantoaxial interspinous distance was found to be remarkably constant and was less than 2.0 in all men and women. This ratio should prove he...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00193824
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:Image-guided percutaneous bone biopsy may be requested by clinicians to guide antibiotics management decisions in patients with extremity osteomyelitis. Much of the clinical literature describes a high rate of bone biopsy culture positivity in patients with osteomyelitis, but anecdotally biopsy is felt to be ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-019-3152-4
更新日期:2019-09-01 00:00:00
abstract::We conducted a radiographic survey of 117 competitive water ski jumpers to determine whether this sport can cause spinal column damage and, if so, whether damage is more likely to occur in those who participate during the period of spinal growth and development (age 15 years or younger). We found a high prevalence of ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00357108
更新日期:1987-01-01 00:00:00
abstract::Thirty-three ultrasound examinations of the corticotomy interval of patients undergoing Ilizarov procedures were retrospectively evaluated for the presence or absence of an acoustic edge artifact. This artifact, consisting of a fine anechoic band, has been previously described in phantom models and is presumed to be d...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00241766
更新日期:1992-01-01 00:00:00
abstract::Magnetic resonance imaging (MRI) plays a critical role in the management pathway of both soft tissue and bone neoplasms, from diagnosis through to post-treatment follow-up. There are a wide range of surgical, oncological, and combined treatment regimes but these rely on accurate histopathological diagnosis. This artic...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-013-1630-7
更新日期:2013-07-01 00:00:00
abstract:UNLABELLED:To evaluate the computed tomography (CT) findings of inflammatory lesions of the sternoclavicular joints (SCJ) in spondylarthropathies. DESIGN AND PATIENTS:CT scans of the SCJs were obtained in 23 patients (group 1) with inflammatory SCJ lesions in spondylarthropathies. These scans were reviewed by four rea...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050258
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:We demonstrate the clinical use of an MR angiography sequence performed with sparse k-space sampling (MRA), as a method for dynamic contrast-enhanced (DCE)-MRI, and apply it to the assessment of sarcomas for treatment response. MATERIALS AND METHODS:Three subjects with sarcomas (2 with osteosarcoma, 1 with h...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-013-1604-9
更新日期:2013-07-01 00:00:00
abstract::The radiological diagnosis of Paget's disease of bone is usually straightforward because most cases conform to well-established classic descriptions. Diagnosis becomes more difficult, however, when radiological appearances are not typical or other disease processes mask or alter the behavior of Paget's disease. Exampl...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF02412358
更新日期:1994-05-01 00:00:00
abstract::Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of unique protein fibrils. Amyloidosis may be hereditary or acquired, and the deposits may be focal, localized, or systemic in distribution. The least common presentation of an amyloid deposition is as a discrete mass called am...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-008-0621-6
更新日期:2009-03-01 00:00:00
abstract::We describe two cases of pigmented villonodular synovitis affecting true bursae. This study was also designed to discuss the term "pigmented villonodular bursitis", not confined to true synovial bursae, sometimes creating misunderstanding. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0491-2
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:To determine the value of prebiopsy 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET)/computed tomography (CT) in discriminating malignant from benign vertebral bone lesions. MATERIALS AND METHODS:This retrospective study included 53 patients with 55 vertebral bone lesions that underwent FDG-...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-020-03426-8
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:Vascular calcifications on the preoperative radiograph of patients scheduled for total knee arthroplasty (TKA) often give rise to concern, as their clinical relevance remains uncertain. The aim of this study was to investigate whether these vascular calcifications-especially medial artery calcifications (MACs...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2681-y
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The description of femoral head sphericity and related risk for femoroacetabularimpingement is currently limited to an angular estimate-the alpha angle-whose relevance and accuracy have been challenged. We developed a three-dimensional approach for both automated digital measurement of the alpha angle and the...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-010-1021-2
更新日期:2011-07-01 00:00:00
abstract::A case of OCC in a 35-year-old woman is presented. Proof was obtained by open biopsy. This rare entity is benign and its etiology is still obscure. No definite association with osteitis pubis or osteitis condensans ilii has been reported. The involvement of the clavicle is invariably unilateral. The clinical and radio...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00193100
更新日期:1990-01-01 00:00:00