Abstract:
:Genome-wide association studies have previously identified variants in SLC30A8, encoding the zinc transporter ZnT8, associated with diabetes risk. A rare variant association study has now established the direction of effect, surprisingly showing that loss-of-function mutations in SLC30A8 are protective against diabetes.
journal_name
Nat Genetjournal_title
Nature geneticsauthors
Pearson Edoi
10.1038/ng.2934subject
Has Abstractpub_date
2014-04-01 00:00:00pages
323-4issue
4eissn
1061-4036issn
1546-1718pii
ng.2934journal_volume
46pub_type
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