Abstract:
:RETINOBLASTOMA (RB) is a tumour suppressor gene originally discovered in patients that develop eye tumours. The pRb protein is now well established as a key cell-cycle regulator which suppresses G1-S transition via interaction with E2F-DP complexes. pRb function is also required for a wide range of biological processes, including the regulation of stem-cell maintenance, cell differentiation, permanent cell-cycle exit, DNA repair, and genome stability. Such multifunctionality of pRb is thought to be facilitated through interactions with various binding partners in a context-dependent manner. Although the molecular network in which RB controls various biological processes is not fully understood, it has been found that pRb interacts with transcription factors and chromatin modifiers to either suppress or promote the expression of key genes during the switch from cell proliferation to differentiation. RETINOBLASTOMA-RELATED (RBR) is the plant orthologue of RB and is also known to negatively control the G1-S transition. Similar to its animal counterpart, plant RBR has various roles throughout plant development; however, much of its molecular functions outside of the G1-S transition are still unknown. One of the better-characterized molecular mechanisms is the cooperation of RBR with the Polycomb repressive complex 2 (PRC2) during plant-specific developmental events. This review summarizes the current understanding of this cooperation and focuses on the processes in Arabidopsis in which the RBR-PRC2 cooperation facilitates cell differentiation and developmental transitions.
journal_name
J Exp Botjournal_title
Journal of experimental botanyauthors
Kuwabara A,Gruissem Wdoi
10.1093/jxb/eru069subject
Has Abstractpub_date
2014-06-01 00:00:00pages
2667-76issue
10eissn
0022-0957issn
1460-2431pii
eru069journal_volume
65pub_type
杂志文章,评审abstract::Sorghum is an important source of food, feed, and biofuel, especially in the semi-arid tropics because this cereal is well adapted to harsh, drought-prone environments. Post-flowering drought adaptation in sorghum is associated with the stay-green phenotype. Alleles that contribute to this complex trait have been mapp...
journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erl225
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journal_title:Journal of experimental botany
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pub_type: 杂志文章
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journal_title:Journal of experimental botany
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erj207
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journal_title:Journal of experimental botany
pub_type: 杂志文章,评审
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journal_title:Journal of experimental botany
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章,评审
doi:10.1093/jexbot/52.363.2043
更新日期:2001-10-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erx314
更新日期:2017-11-02 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erh207
更新日期:2004-08-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章,评审
doi:10.1093/jxb/ert099
更新日期:2013-06-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/eru395
更新日期:2014-12-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/ers253
更新日期:2012-10-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erm017
更新日期:2007-01-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erp366
更新日期:2010-02-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
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更新日期:2020-03-25 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jexbot/51.347.1127
更新日期:2000-06-01 00:00:00
abstract::Two cultivars of spring wheat (Triticum aestivum L.) were grown to maturity in hydroponic cultures. Nitrogen accumulation was controlled by daily growth-limiting additions of nitrate together with all other nutrients in excess. Six different curves of N accumulation were used, with the same relative changes from day t...
journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jexbot/51.352.1921
更新日期:2000-11-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erz446
更新日期:2020-01-07 00:00:00
abstract::A gene MtPPRD1, encoding a protein of 132 amino acids containing a proline-rich domain (PRD), has been revealed by suppressive subtractive hybridization (SSH) with two mRNA populations of embryo axes harvested immediately before and after radicle emergence. Although at the protein level MtPPRD1 showed low homology wit...
journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/eri077
更新日期:2005-03-01 00:00:00
abstract::Arabinogalactan proteins (AGPs) comprise a family of hydroxyproline-rich glycoproteins that are implicated in plant growth and development. In this study, 69 AGPs are identified from the rice genome, including 13 classical AGPs, 15 arabinogalactan (AG) peptides, three non-classical AGPs, three early nodulin-like AGPs ...
journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/erq104
更新日期:2010-06-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章,评审
doi:10.1093/jxb/erp117
更新日期:2009-01-01 00:00:00
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journal_title:Journal of experimental botany
pub_type: 杂志文章
doi:10.1093/jxb/eraa116
更新日期:2020-07-25 00:00:00
abstract::This article reviews the historical development of cytology and cytogenetics in Arabidopsis, and summarizes recent developments in molecular cytogenetics, with special emphasis on meiotic studies. Despite the small genome and small chromosomes of Arabidopsis, considerable progress has been made in developing appropria...
journal_title:Journal of experimental botany
pub_type: 杂志文章,评审
doi:10.1093/jxb/erg034
更新日期:2003-01-01 00:00:00