Abstract：
:Drosophila melanogaster, an ancestrally African species, has recently spread throughout the world, associated with human activity. The species has served as the focus of many studies investigating local adaptation relating to latitudinal variation in non-African populations, especially those from the United States and Australia. These studies have documented the existence of shared, genetically determined phenotypic clines for several life history and morphological traits. However, there are no studies designed to formally address the degree of shared latitudinal differentiation at the genomic level. Here we present our comparative analysis of such differentiation. Not surprisingly, we find evidence of substantial, shared selection responses on the two continents, probably resulting from selection on standing ancestral variation. The polymorphic inversion In(3R)P has an important effect on this pattern, but considerable parallelism is also observed across the genome in regions not associated with inversion polymorphism. Interestingly, parallel latitudinal differentiation is observed even for variants that are not particularly strongly differentiated, which suggests that very large numbers of polymorphisms are targets of spatially varying selection in this species.
journal_name
Geneticsjournal_title
Geneticsauthors
Reinhardt JA,Kolaczkowski B,Jones CD,Begun DJ,Kern ADdoi
10.1534/genetics.114.161463subject
Has Abstractpub_date
2014-05-01 00:00:00pages
361-73issue
1eissn
0016-6731issn
1943-2631pii
genetics.114.161463journal_volume
197pub_type
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