Abstract:
UNLABELLED:Capsular contracture remains a major complication after reconstructive or aesthetic breast augmentation. Formation of capsular fibrosis is a multifactorial process. An initial inflammatory reaction appears to be key to the development of capsular contracture. Recent studies have shown that pulsed acoustic cellular expression (PACE) has significant antiinflammatory effects. Thus, this study aimed to determine the potential of PACE to prevent or attenuate capsular contracture around silicone implants in a rodent model. For this study, 36 Lewis rats were divided into two groups, and a textured silicone implant was placed in a dorsal submuscular pocket. One group received PACE treatment, whereas the other group served as the control group and received no treatment. Follow-up evaluations were performed after 10, 35, and 100 days. Capsule thickness, collagen density, myofibroblasts, vascular density, and a semiquantitative real-time polymerase chain reaction that addressed differential gene expression were assessed. The PACE treatment significantly reduced capsule thickness on days 10, 35, and 100 compared with the control group (day 10: 632.9 ± 164.5 vs 932.6 ± 160.8, p < 0.05; day 35: 709.5 ± 175 vs 825.9 ± 313.3, p < 0.0.5; day 100: 736.3 ± 198.1 vs 1,062.3 ± 151.9, p < 0.05). This was accompanied by a significant suppression of proinflammatory genes (cluster of differentiation 68, monocyte chemotactic protein-1, CCL4) and synergistic alterations of pro- and antifibrotic proteins (transforming growth factor-beta 1, matrix metalloproteinase-2). This study showed that the PACE application significantly reduces capsular contracture around silicone implants. A decrease in capsular thickness after PACE treatment seems to be associated with a downregulation of proinflammatory genes and proteins. The study identifies PACE technology as a potential low-cost technique that is easy to use for reduction of capsular contracture after augmentation using silicone implants. NO LEVEL ASSIGNED:This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors http://www.springer.com/00266 .
journal_name
Aesthetic Plast Surgjournal_title
Aesthetic plastic surgeryauthors
Reichenberger MA,Heimer S,Lass U,Germann G,Köllensperger E,Mueller W,Hirsch T,Fischer Sdoi
10.1007/s00266-013-0235-9subject
Has Abstractpub_date
2014-02-01 00:00:00pages
244-251issue
1eissn
0364-216Xissn
1432-5241pii
10.1007/s00266-013-0235-9journal_volume
38pub_type
杂志文章abstract::In the past few years the approach to lower blepharoplasty complications has evolved. New and worthy preventive and curative treatments have been suggested for both scleral show and ectropion (operations with or without interruption of the lid margin, mucosal grafts, orbicularis flaps, etc.). Among these, several tech...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002669900214
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:In order to correct upper lid laxity, upper blepharoplasty, subbrow excision, and forehead lift have been utilized. Our newly developed subbrow excision attaches the orbicularis oculi muscle to the frontalis muscle. This improves the longevity of the result without inhibiting the gliding plane of the periorb...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-01879-9
更新日期:2020-12-01 00:00:00
abstract::The aging female with excess arm fat and poor skin tone frequently refuses a brachioplasty scar due to permanent detectability. Traditional deep liposuction localized to the posterolateral aspect of the arm frequently leaves sagging, wrinkled skin. Circumferential para-Axillary Superficial Tumescent (CAST) liposuction...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002669900144
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:Reduction mammoplasty in patients with gigantic breast hypertrophy runs a high risk of complication. Traditionally, inferior pedicle reductions or free nipple grafting techniques have been recommended for gigantic breasts on the basis of measurements and expected resection weights. The superiomedial pedicle ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-01973-y
更新日期:2020-09-22 00:00:00
abstract::The authors describe six procedures used for the correction of various symptoms of the aging process in the perioral region, featuring augmentation cheiloplasty and smoothening of the nasolabial crease. ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF01570237
更新日期:1976-12-01 00:00:00
abstract:BACKGROUND:Surgery of the abdominal cavity may lead to postoperative defects to the ventricular segment of the abdominal wall. The reconstruction of these defects, especially in the area of the median line, represents an issue during the course of healing due to the role of the abdominal cavity in respiratory processes...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-016-0626-9
更新日期:2016-06-01 00:00:00
abstract::Dermatofibrosarcoma protuberans is a rare soft tissue cancer of the skin with the potential for intermediate malignity, characterized by local invasion and recurrence. Presenting with local atrophic and sometimes erythematous plaques, these lesions are best treated with surgery in which large excisions are necessary t...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-003-0107-9
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Nasal valve collapse is relatively common with a lifetime prevalence of up to 13%. Etiologies include prior rhinoplasty, other surgical procedures, facial paralysis, congenital defects, trauma, and aging. Internal nasal valve collapse leads to impairment of nasal breathing, which significantly disturbs quali...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章,评审
doi:10.1007/s00266-020-02075-5
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:Brachioplasties often culminate in unsightly scars that are a source of disappointment to patients. We aimed to evaluate the results of M-Y axilloplasty following massive weight loss. PATIENTS:We performed a retrospective assessment of our technique for brachioplasty with an M-Y axilloplasty in 159 female p...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-018-1133-y
更新日期:2018-08-01 00:00:00
abstract::Improvements have been made throughout the history of medicine, causing physicians to abandon a technique or medications clearly shown to be suboptimal. Unfortunately, this has not happened with rejuvenative surgery. Conventional lower eyelid procedures continue to include removal of orbital fat in most cases, and fac...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章,评审
doi:10.1007/s00266-004-4019-0
更新日期:2004-07-01 00:00:00
abstract::The authors present a new approach to handling the problem of extrusion of mammary implants. The prosthesis is removed and reintroduced in the same operation. Five cases are discussed. ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF00454318
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The authors have developed a new digital photogrammetric method of facial analysis known as balanced angular and proportional analysis (BAPA). Using BAPA, the authors analyzed the faces of attractive Korean entertainers. METHODS:The BAPA approach involves 28 landmarks and 14 measurements (10 proportional an...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-008-9257-0
更新日期:2009-03-01 00:00:00
abstract::In the Orient, faces are usually wide and short. This physical characteristic is often undesirable in many Asian cultures. Consequently, reduction malarplasty is one of the most common aesthetic procedures performed in the Orient. Previously described techniques for malar reduction such as intraoral chiseling or the b...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002669900298
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:There are multitudes of procedures in plastic surgery used to correct hypertrophic and pendulous breasts in patients with heavy and ptotic breasts who need great resections of breast tissue, where the suprasternal notch-to-nipple distance is long and the use of nipple-areola transposition techniques is a cha...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-008-9163-5
更新日期:2008-07-01 00:00:00
abstract::Most descriptions of the skin-muscle flap lower lid blepharoplasty, the so-called McIndoe technique, indicate dissection of the flap in a cephalad-to-caudad direction from near the ciliary margin toward the bony orbital rim. However, this report describes a technical variation in which counter-traction and lateral-to-...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF01570650
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Several different methods have been proposed for treatment of gynecomastia, depending on the amount of breast enlargement and skin redundancy. The liposuction pull-through technique has been proposed as an efficacious treatment for many gynecomastia cases. This work aims to study the outcome of this techniqu...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-016-0749-z
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Irradiation therapy is an important pillar in the treatment of breast cancer. However, it can trigger capsular fibrosis, the most significant complication of implant-based breast reconstruction. As collagen is the main component of fibrotic capsules, the collagenase of the bacterium Clostridium histolyticum ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-018-1267-y
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:This study aimed to explore the treatment of capsular contracture after augmentation mammaplasty by insertion of a breast prosthesis anterior to the original capsule. METHODS:Through transaxillary or submammary incisions and small capsular incisions, 14 patients (18 breasts) with Baker grades 3 and 4 capsul...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-011-9733-9
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Hypermelanosis includes a diverse group of genetic and acquired skin anomalies that appear as darker, hyperpigmented areas. Melasma, in particular, is a hypermelanotic condition that affects sun-exposed skin in females. Whether this condition is acquired or genetic is still controversial. However, it clearly...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-010-9485-y
更新日期:2010-08-01 00:00:00
abstract::The technique described in this article correcting the protruding ear deformity has evolved over 40 years. The original procedures and our subsequent modifications are described, including 20-year followup results. The possible pitfalls in carrying out this procedure and how to avoid them are also described. A relativ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF00453877
更新日期:1995-09-01 00:00:00
abstract::Liposuction or its modifications have become accepted therapy for hyperhidrosis. During the nearly 20 years since its introduction, the actual anatomic removal of sweat glands has not been investigated. In this study, three patients underwent axillary liposuction and histologic examination of the aspirates. Apocrine s...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-006-0192-7
更新日期:2007-01-01 00:00:00
abstract::As more people seek body contour surgery spurred on by the media's great interest in suction lipectomy and the seemingly increasing numbers of satisfied patients, we should re-examine an area where results of body contour surgery have been less satisfying, the inner thigh. In those patients whose problem remains skin ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF01571478
更新日期:1989-04-01 00:00:00
abstract::Gender-reassignment therapy, especially for reshaping of the forehead, can be an effective treatment to improve self-esteem. Contouring of the cranial vault, especially of the forehead, still is a rarely performed surgical procedure for gender reassignment. In addition to surgical bone remodeling, several materials ha...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-011-9731-y
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The recent rise in popularity of minimally invasive facial aesthetic procedures has resulted in the overall heightened patient interest in lip rejuvenation. There is a variety of techniques and modifications for surgical upper lip enhancement described in the literature but no single method is considered opt...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-01871-3
更新日期:2020-07-16 00:00:00
abstract:BACKGROUND:Evaluation of outcomes after aesthetic surgery still is a challenge in plastic surgery. The evaluation frequently is based on subjective criteria. This study used a new clinical grading scale to evaluate aesthetic results for plastic surgeries to the abdomen. The method scores each of the following five para...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-011-9776-y
更新日期:2012-02-01 00:00:00
abstract::The tumescent technique is very effective for subfascial breast implant surgery. A total amount volume of 330 cc (120/160 cc for each breast) ensures a clean and bloodless field, leading to less postoperative bruising and prolonged local anaesthesia effects. The surgical procedure can be performed with or without asso...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-01723-0
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:This preliminary ex vivo study aimed to clarify the pathophysiologic mechanisms of fat tissue depletion by subcutaneous drug application. Therefore, the lipolytic effects of phosphatidylcholine plus deoxycholate (Lipostabil) (L) and of deoxycholate (DC) alone were compared with those of sodium chloride (NaCl...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-014-0371-x
更新日期:2014-10-01 00:00:00
abstract::This is the first report of a case of aesthetic calf augmentation with microvascular transferred autologous material. The technique regarding to calf augmentation using silicon prostheses is described and the advantages and disadvantages of this method are discussed. This should incite discussion on the use of free-fl...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002669900083
更新日期:1997-01-01 00:00:00
abstract:UNLABELLED:Adipose patients, especially after massive weight loss, pose a challenge to the breast surgeon due to the major loss of volume and the inelasticity of the skin. Rubin described a suitable mammaplasty technique for these patients involving dermal suspension sutures and total parenchymal reshaping. With this t...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-013-0223-0
更新日期:2013-12-01 00:00:00
abstract::An examination of the naso-frontal angle shows that a cranial or caudal shift in position affects the dorsum length. The fundamental aspect characterizing the naso-frontal angle is its width: it may be normal, too wide, or too narrow. It's easier to modify a too-narrow angle than a too-wide one. We show surgical techn...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002660010085
更新日期:2001-01-01 00:00:00