[Benzalkonium chloride for vaginal contraception--the vaginal sponge].

Abstract:

:From March 1986 to December 1987, a vaginal contraceptive, not yet commercially available in Germany, was studied in 56 women. The substance benzalconium chloride (BZC) was contained in vaginal sponges (n = 46), pessaries (n = 4) and cream (n = 6) at a dose rate of 1.18%. BZC is a surfactant of the ammonium series that ruptures the spermatozoal membrane. It is also a powerful bactericide and viricide. The advantages of the vaginal sponge (intercourse is safe immediately after insertion for the next 24 h and for multiple intercourses) made it pleasant for the women. The rate of transitory local side effects (16%) was acceptable. The vaginal contraception did not interfere with the sexual life. In 645 months of use 10 pregnancies occurred of which 9 happened with the sponge (PI 20.3). Its fixation before the cervix and the release of the spermicide is not reliable enough, so that we cannot recommend the sponge as a safe vaginal contraceptive.

authors

Meyer U,Gerhard I,Runnebaum B

doi

10.1055/s-2008-1026298

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

542-7

issue

7

eissn

0016-5751

issn

1438-8804

journal_volume

50

pub_type

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