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The influence of timing of polysomnography on diagnosis of obstructive sleep apnea in patients presenting with acute myocardial infarction and stable coronary artery disease.

Abstract：

BACKGROUND:We aimed to determine if timing of polysomnography (PSG) influences the diagnosis of obstructive sleep apnea (OSA) in acute myocardial infarction (AMI) or stable coronary artery disease (CAD). METHODS:A total of 160 patients admitted with AMI or stable CAD were consecutively recruited for either in-hospital (n=80) or postdischarge (n=80) PSG. RESULTS:The median time from admission to PSG for the in-hospital and postdischarge groups was 1 day and 17 days, respectively (P<.001). Overall, 59 patients (36.9%) were diagnosed with OSA (apnea-hypopnea index [AHI] > or = 15), and they were more likely to have diabetes mellitus (DM), hypertension, hyperlipidemia, chronic renal failure, and a greater body mass index (BMI) (P<.05 for all). The diagnosis of OSA was significantly higher (P=.037) in patients who had a PSG performed as an inpatient than those who had a PSG as an outpatient. There was a significant interaction between clinical presentation and the effect of PSG timing on the diagnosis of OSA (P=.003). For the patients presenting with AMI but not those with stable CAD, in-hospital PSG was an independent predictor of OSA (adjusted odds ratio, 3.84 [95% confidence interval, 1.42-10.41]; P=.008). CONCLUSION:The timing of PSG influenced the diagnosis of OSA in patients who presented with AMI but not in those who presented with stable CAD.

journal_name

Sleep Med

journal_title

Sleep medicine

authors

Low TT,Hong WZ,Tai BC,Hein T,Khoo SM,Tan AY,Chan MY,Richards M,Lee CH

doi

10.1016/j.sleep.2013.03.025

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

985-90

issue

10

eissn

1389-9457

issn

1878-5506

pii

S1389-9457(13)00219-0

journal_volume

14

pub_type

临床试验,杂志文章

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