Abstract：
AIM:Outcome of patients with locally advanced non-small-cell lung cancer (NCSLC) is generally poor, with five-year survival rate of only 23%, when patients are treated with surgery only. The presentation of positive adjuvant therapy trials in NSCLC has changed clinical practice, doubling the number of patients with completely resected NSCLC referred for adjuvant chemotherapy since 2004. Furthermore, few large studies described a large number of stage III patients in non-Asiatic patients and they showed controversial results about survival in completely resected stage IIIA NSCLC. The objective of this study was to evaluate the impact of adjuvant chemotherapy in completely resected stage IIIA NCSLC, administered on a routine basis, outside clinical trials. METHODS:This is a retrospective study of patients with stage IIIA NCSLC treated between 1990 and 2008, and included in a continuous, consecutive database. Inclusion criteria were: age >18 years, complete surgical resection, and pathologically confirmed as stage IIIA. The following clinical data were obtained: age, gender, performance status, histological type, chemotherapy regimens, status at last follow-up and hospital where the treatment occurred. Kaplan-Meier's method was used to determine actuarial survival. Differences in survival were determined by Breslow and log rank analyses. RESULTS:According to these inclusion criteria, 415 patients were considered for the present study. The median follow-up time of all patients was 38.2 months. The adjuvant chemotherapeutic treatment affected survival significantly (P <0.001). Also the type of chemotherapeutic treatment affected survival (P ≤0.001). CONCLUSION:Cisplatin-based adjuvant chemotherapy was beneficial in patients who had a completed resected stage IIIA carcinoma.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Naim Younes R,Gross JL,Abrao FG,Rodrigues Pereira Jsubject
Has Abstractpub_date
2013-04-01 00:00:00pages
169-74issue
2eissn
0026-4733issn
1827-1626pii
R06135949journal_volume
68pub_type
杂志文章,评审abstract：:Personal experience with papillotomy and papillosphincterotomy in calculosis of the PBD is reported. The indications and results obtained are discussed. The techniques employed are described and an assessment is made of the extent to which these operations can be performed without causing unnecessary damage to the sph...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1978-06-30 00:00:00
abstract：:Between January 1989 and December 1994 we accomplished 130 CT-guided transthoracic fine needle aspirations (FNA) in 120 patients. Ten patients underwent a second FNA because of the negativity and doubts of the first. Diagnosis was targeted in 114 (95%) patients and 89% showed cytological evidence of malignancy. FNA-CT...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The anatomical region identified with the "head and neck region" has got the highest functional concentration of the human body and the highest incidence of malignant tumours per unit of surface. A pathology, that forced to serious and destroying surgical interventions in this area, will carry necessarily out a series...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:Successful resection of a leiomyoma of the epicardial segment of the oesophagus in a personal cases is reported. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1976-03-31 00:00:00
abstract：AIM:The aim of this article is to present a new method for treating spontaneous pneumothorax, the one window plus puncture method (1WP) in which a thin endoscope is used. METHODS:With the patient in the lateral position and under one-lung ventilation, a one-window working port was created on the ventral side. An intro...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:A series of cases of acute pancreatitis treated between 1-XI-1972 and 1-XI-1975 is presented. A division is made between cases acute ab initio and postoperative pancreatitis, the latter further subdivided into pancreatic necroses, oedemas, and slight affections. The question of diagnosis is examined and elements indic...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1976-10-31 00:00:00
abstract：:In order to evaluate the clinical utility of autologous splenic transplantation in the omental pouch, a pneumococcal challenge was performed in 3 groups of rats, after demonstration of vitality of the intraperitoneal inoculum: Group A: splenectomized rats; Group B: reimplanted rats; Group C: sham operation. No statist...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:The authors outline the stages of abdominoperineal surgery due to rectal cancer to achieve the reconstruction of perineal-stomic continence. The operation is simple to perform, without particular vascular risks and sepsis; it does not necessitate temporary abdominal colostomy and, lastly, does not oblige postoperative...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-06-30 00:00:00
abstract：:A comparative experimental study was conducted on three different suture techniques for end-to-end colonic anastomoses. The development of stenosis, perivisceral adhesions and resistance to endoluminal pressure were assessed. The results show that the one layer all-coat interrupted stitch anastomosis displays less res...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-04-15 00:00:00
abstract：:The results obtained in 10 patients suffering from complicated diverticulitis are reported, stress being laid on the seriousness of the pathology and proposing that emergency surgery be carried out. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-03-31 00:00:00
abstract：:Three cases of diverticulum of the IV duodenal portion are presented. The Authors, after having summarized the general features of the duodenal diverticula, remembered the rareness of the ones of its fourth portion, describe the clinical cases and conclude synthetizing the main indications to this type of surgery: com...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-09-15 00:00:00
abstract：:Personal experience of short-term chemoprophylaxis with piperacillin in 261 consecutive "clean" and "non-contaminating" operations is reported. Piperacillin was employed in a dose of 2 g i.m. every 8 hours for a total of 48 hours, the first administration being carried out at the same time as pre-anaesthesia. Results ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Surgical treatment of advanced forms of spinocellular carcinoma of the oral cavity (stages 3-4) has been integrated for a number of years with cycles of chemo- and/or radiotherapy both before and after surgery. This chemo-radio-surgical therapeutic protocol consists of four distinct stages, separated by precise treatm...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:Following a discussion of the various methods of colorectal anastomosis in cancer surgery, the Authors describe a technical variant using a mechanical stapler in a high rectal location. The rapidity of anastomosis as well as the decreased risk of dehiscence, fistula and stenosis are underlined. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-09-30 00:00:00
abstract：:A multicentre study has been done to evaluate the effectiveness and safety of pefloxacin, a new fluoroquinolone, when given intravenously for surgical prophylaxis. 440 patients (224 males, 216 females), mean age 51.7 +/- 27.3 (SD) years and mean weight 68.4 +/- 12.6 kg, were admitted to the study. The diagnoses for ad...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1994-10-01 00:00:00
abstract：:A new system has been developed for transanal endoscopic microsurgery (TEM), which allows all the conventional surgical techniques within the rectal cavity. The main indication is the removal of sessile adenomas. "Early rectal carcinomas" are also suitable for local excision. We perform local excision of advanced canc...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-06-30 00:00:00
abstract：INTRODUCTION:Surgical management of external rectal prolapse (ERP) remains a challenge with the breadth of choices available and varies on the international, national, regional and locoregional level. Significant innovation has led to new techniques to manage ERP including changes to both abdominal and perineal approac...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4733.16.07205-9
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Numerous hypotheses are called to explain the beneficial effect on glucose metabolism after bariatric surgery. Some authors advocate for the secretion and release of various substances with endocrine functions for the explanation on this event. One of the substances most marked as effector, with contrasting ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.18.07681-2
更新日期：2019-02-01 00:00:00
abstract：INTRODUCTION:Over recent years, minimally invasive hepatic resections have increasingly been reported in the literature. Even though hepatic surgery is still considered a challenge for surgeons due to its technical difficulties and high morbidity, the development and spread of robotic surgery has highlighted a new inte...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Peripheral lymphadenopathy can be caused by benign disease, or it could be a manifestation of underlying hematological disease or metastasis of a yet undiagnosed malignant condition. Fine-needle aspiration cytology (FNAC) and image-guided core biopsy usually make up the first line of investigation. There are...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.18.07752-0
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:The authors report the gynaecological pathology of surgical interest occurring in an Emergency Department in the first half of 2000 and occasionally found during an operation in women who presented a pelvic mass or abdominal pain. METHODS:Six women, average age of 50 years, reached the Emergency Department:...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2002-10-01 00:00:00
abstract：:Esophagectomy is a surgical operation which requires technical expertise to decrease the morbidity and mortality frequently associated with this advance procedure. Various minimally invasive esophagectomy techniques have been developed to decrease the negative impact of esophageal resection. Recently, robotic assisted...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2013-10-01 00:00:00
abstract：:A case of endothoracic goitre with crossed, left-right, retrovascular, retro-tracheo-oesophageal migration is used as the basis for pathogenetic and diagnostic discussion and for stressing the surgical importance of correct topographic and migratory classification of each form. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1977-02-28 00:00:00
abstract：:The aetiology and clinical manifestations most commonly noted in pseudocysts of the pancreas are briefly described. Particular attention is given to the treatments of lesions operated under emergency conditions and the clinical aspects of pancreatic effusions sometimes encountered during the course of the disease. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1977-05-15 00:00:00
abstract：:Cancer of the extrahepatic biliary tract is a rare disease related to a severe prognosis. The resection of the extrahepatic biliary tract is a complex procedure and the preoperative assessment of resectability is made difficult because of the malignancies. Biliary cancer resection can be curative in some patients but ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The finding of Merkel cell carcinoma is a rare but important event owing to the highly aggressive nature of this neoplasm. The authors report three cases of Merkel cell carcinoma with different onsets which were representative of the possible range of clinical symptoms and the prognosis of this pathology. In two cases...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：:Echotomography was used in the diagnosis of abdominal disease in children. The results obtained were compared with those given by conventional methods. The soundness of echotomography in the location and indication of the size and structure of lesions was demonstrated in a series of 20 cases. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1978-05-15 00:00:00
abstract：:Totally implantable central venous accesses systems are presently widely used in cancer patients. Perioperative and long-term morbidity of 750 consecutive implants performed from 1985 to 1994 were retrospectively reviewed. Our Series consisted in 616 (82.1%). Ports and 134 (17.9%) external tunnelled catheters with sub...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：AIM:This prospective study was done to evaluate the efficacy of commercial fibrin glue application in the healing of patients with fistulas-in-ano from a short follow up period (one year). METHODS:This randomized clinical trial of 26 patients was performed during the period from January 2012 to July 2012. Nineteen men...
journal_title：Minerva chirurgica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-08-01 00:00:00
abstract：:An experience of 1240 patients suffering from varicose veins of the lower limbs and operated from December 1987 to October 1992, is reported. In order to obtain an objective valuation of functional and aesthetic results, a table with subjective symptoms and clinical and instrumental signs was filled in, before the sur...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-06-01 00:00:00
