Abstract：
BACKGROUND:Numerous hypotheses are called to explain the beneficial effect on glucose metabolism after bariatric surgery. Some authors advocate for the secretion and release of various substances with endocrine functions for the explanation on this event. One of the substances most marked as effector, with contrasting effects but controversial data, is GLP-1. METHODS:Our study was performed in healthy male Wistar rats, to avoid the absence of confounding factors such as T2DM and obesity. In order to know the adaptation of GLP-1 secretion after surgery 5 groups were designated: two control groups (fasting and surgical stress), and three surgical groups (gastric sleeve, 50% resection of the midgut and the Roux en Y gastric bypass). After three months the GLP-1 synthesis in the different portions of the small intestine and the expression of the membrane receptors in pancreatic islet cells were studied by immunohistochemical techniques. RESULTS:There was a significant increase in the number of secretory cells in ileum, duodenum and jejunum in mixed (RYGB) and malabsorptive (RI50) surgical groups. An elevation of pancreatic receptors signal was also observed in the same techniques versus controls. CONCLUSIONS:Our data indicate that intestinal secretion of GLP-1 and its sensitivity to the pancreatic changes were increased like a response of an adaptive effect to the mechanical aggression of the digestive tube and as alteration of nutrient flow after surgery.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Moreno-Arciniegas A,Falckenheiner-Soria J,Bancalero-De Los Reyes J,Camacho-Ramírez A,de Los Angeles Mayo-Ossorio M,Pacheco-García JM,Pérez-Arana GM,Prada-Oliveira JAdoi
10.23736/S0026-4733.18.07681-2subject
Has Abstractpub_date
2019-02-01 00:00:00pages
7-13issue
1eissn
0026-4733issn
1827-1626pii
S0026-4733.18.07681-2journal_volume
74pub_type
杂志文章abstract：:Pancreatoblastoma is a very rare tumor of the pancreas, affecting children in the first decade of life. Ultrasound and CT scan may be useful but pre-operative diagnosis is often quite difficult. High level of seric alpha-fetoprotein could be suggestive of pancreatoblastoma. The definitive diagnosis is however made by ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Solitary fibrous tumors of the pleura represent a rare clinicopathological entity: 456 cases only have been reported since 1991. A interesting case of solitary fibrous tumor of the pleura is described here, because it turned up in a female patient followed up for a bilateral breast cancer and so with the exact determi...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：:The authors present their personal experience of three cases of bronchial fistulae post pneumonectomy or lobectomy. Surgical treatment was not done directly on the bronchial stump but by thoracoplasty. This approach to the thoracic chest gets good results on condition that stabilization in reexpansion of residual pare...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:The paper reports a case of splenic rupture during the course of chronic pancreatitis, an event rarely reported in the literature. The anatomical arrangement of organs and peripancreatic vessels is a predisposing factor for this complication. There are essentially three different but correlated pathogenetic hypotheses...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:This study aims to check the presence and the role of the Mycobacterium tuberculosis infection, in an Ambulatory and Day Surgery Out-Patient Centre. METHODS:Two periods of activity in this Centre are evaluated corresponding separately to the years 1989-1993 and 1994-1998 and the total number of patients, co...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2003-02-01 00:00:00
abstract：:Emergency surgery is required for performed colonic diverticulitis. Surgical indications are not uniform in literature. In the experience of the authors the operations have been performed in the case of peritonitis subsequent to the perforation or in the case of failure of the conservative treatment. Twenty-four patie...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:A 54 year-old man, without any remarkable medical history, was examined for recurrent episodes of colicky abdominal pain, over a period of nine months, with positive faecal occult blood test. Three months earlier he had undergone an extensive evaluation for a single episode of melaena, including upper gastrointestinal...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:Sorbsan is a new dressing composed of alginate fibers extracted from seaweed. It is claimed to have important hydrophilic, haemostatic and biocompatible qualities. Sorbsan was used in the treatment of the donor site of split skin grafts in 52 patients operated in this department from 1988 to 1990. The patients of this...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-06-15 00:00:00
abstract：:Late thrombosis of inserted prosthetic grafts for arterial reconstructive surgery is one of the most frequent late complication. Its incidence is influenced by many factors: hemodynamic conditions, quality of run-in and run-off, technical aspects of the primary repair. Progressive arteriosclerosis in femoral vessels w...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-03-31 00:00:00
abstract：:Videolaparoscopic cholecystectomy is considered the treatment of choice for simple cholelithiasis. Now many surgeons consider the laparscopic procedure usable also in the complicated biliary lithiasis like acute cholecystitis and choledocholithiasis. The authors report their recent experience of the laparoscopic treat...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Thyroidectomy is one of the most frequently performed surgical procedure worldwide, even if the risks of lethal postoperative complications prevented its evolution and diffusion until the beginning of the XX century. At that time, T. Kocher described his meticulous technique, reporting excellent results in terms of mo...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2007-10-01 00:00:00
abstract：:Primitive tumor of the liver, associated with cirrhosis with 40-80% of incidence, isn't one of the most common malignant neoplasms in the western area but it holds low survival and diminished possibilities of radical exeresis. A few years ago it has enrolled several non-invasive imaging-guided techniques, alternative ...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:Neoadjuvant therapy is recommended for patients with borderline-resectable pancreatic cancer (BRPC). In this study, we compare survival outcomes of neoadjuvant therapy with upfront surgery. METHODS:From January 2011 to June 2016, 1415 patients underwent treatments for pancreatic cancer in Samsung Medical Ce...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.19.07958-6
更新日期：2020-02-01 00:00:00
abstract：:The behaviour and distribution of "vasa recta" in the jejunum-ileal tract of the small intestine are described. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1975-07-15 00:00:00
abstract：AIM:Gastro-esophageal reflux disease (GERD) has emerged as one of the most common diseases in modern civilization. We investigated functional evaluation after total fundoplication without division of short gastric vessels and review of literature. METHODS:From January 2007 to June 2008 43 patients with chronic gastroe...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：:Senology is going to be an independent branch, but resistances to the acknowledgement of the senologist as a devoted professional are still under way. Nevertheless, in the last 20 years an irreversible educational training was traced out. The senologist is not only the surgeon who operates on the breast: he is also a ...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2005-12-01 00:00:00
abstract：:Immediate and long-term results in 250 PSP operations associated with WSP in 116 cases are reported. Complications and failures are described and evaluated, while their causes and possible connection with the type of operation employed are explained. Examinations carried out in the assessment of long-term results are ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1976-03-15 00:00:00
abstract：:Of 220 patients operated for gastric cancer, 74 with subtotal gastrectomy and 145 with total gastrectomy (60 with lymphadenectomy), the results and indications for total gastrectomy extended with lymphadenectomy are analysed. The importance of lymph node emptying in relation to the possibility of breakdown of the lymp...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-05-15 00:00:00
abstract：:The authors report their experience using biofragmentable anastomosis ring (BAR) in bowel anastomosis. Starting January 1993 to February 1994, 46 intestinal anastomoses were performed using BAR, and particularly 39 end-to-end colo-colostomies, 2 end-to-side colo-colostomies and 5 end-to-side ileo-colostomies. 35 patie...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：:Nine years experience of anorectal surgery for Crohn-related lesion have been analysed. The series regards only 14 cases with pathology including ragade, abscesses and anocutaneous and retrovaginal fistulas. Treatment was as conservative as possible except for cases in which fistulizations led to sepsis as a result of...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-06-30 00:00:00
abstract：:Morbid Obesity is increasing worldwide at fast pace with associated co-morbidities also on the rise. Considering that Obesity is one of the main risk factor for developing a Ventral Hernia this will results that in the future we will experience a rise in those hernia in patients undergoing any abdominal surgery. There...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.20.08497-7
更新日期：2020-11-09 00:00:00
abstract：:The role of some so-called primary and secondary (or oligo-elements) elements in the physiopathology of the cardiocirculatory system has been well known from a number of years and they have been regularly included in the treatment protocols. Some, including K, Ca, Mg and Zn, are extremely well known and widely used in...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:Carotid-jugular arteriovenous fistulas (AVF) are extremely rare with only 20 cases reported in the literature up to December 1996. The case of a 74-year-old man (the oldest reported in the literature) with abnormal communications between the external carotid artery and the internal jugular vein is reported. The condit...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：BACKGROUND:In gastric cancer surgery, to search for a technique to remove the entire posterior mesogastric region using a standardised operation using well defined methods and anatomic-embryological planes. METHODS:A concise description of the embryological evolution of the posterior mesogastrium allow the formation o...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：2000-10-01 00:00:00
abstract：:A typical case of spontaneous rupture of the oesophagus (Boerhaave's syndrome) successfully operated at the Surgery Division of the Lodi Greater Hospital is presented. An account of the aetiopathogenetic, anatomopathological and clinical problems involved is followed by an examination of the possibilities of diagnosis...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1975-10-15 00:00:00
abstract：:Cholangiography carried out in laparoscopic surgery is a diagnostic exam considered by many authors to be very important for the anatomy and the research pre-existent pathologies of the biliary tree. Such are the effective advantages that many Schools suggest it be carried out any case as the risks, the costs and the ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:Gastro-intestinal foreign bodies are a by no means rare event in surgery and in the USA mortality is about 1500 people per annum. The surgical treatment of foreign bodies in the alimentary tract is reported here. Certain cases of voluntary ingestion in mental patients are reported, comparing personal experience with t...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:Two personally observed cases of ischaemia of the lower extremities due to thrombosis caused by a popliteal aneurysm are presented. While surgery is known to be treatment of choice, in these cases locoregional fibrinolysis was preferred. It seems useful to detail the advantages of this approach that has never appeared...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-05-31 00:00:00
abstract：:The authors report their experience on 313 liver transplantations performed in 255 patients. In 51.7% the indication to liver transplant was the cirrhosis, post alcoholic in 39.5% and post-hepatitis in 24.1%. The global mortality was 34.9% (89/255) with an actuarial survival of 53% at 74 months. We registered 10 cases...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-09-30 00:00:00
abstract：:Forty-nine consecutive patients with early gastric cancer (EGC), observed from January 1978 to December 1992 in the Surgery Department of our Institute, were included in a retrospective study. The EGC prevalence in the overall cases of gastric cancer was 11%. This frequency was 8% in the period 1978-1985 and 15% in th...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
