当前位置： SCI文献检索 > INTERNATIONAL ORTHOPAEDICS期刊下所有文献 > No effect of subperiosteal growth factor application on periosteal neo-chondrogenesis in osteoperiosteal bone grafts for osteochondral defect repair.

No effect of subperiosteal growth factor application on periosteal neo-chondrogenesis in osteoperiosteal bone grafts for osteochondral defect repair.

Abstract：

PURPOSE:The purpose of this study was to examine the effect of subperiosteal injection of chondroinductive growth factors on the histological and biomechanical outcome of autologous osteoperiosteal grafts. METHODS:Thirty six standardised osteochondral defects were created in the trochlear groove of 18 Göttinger Minipigs and evaluated after six, 12 and 52 weeks. Defects were treated with press-fit implantation of autologous osteoperiosteal cylindrical block-grafts with or without subperiosteal injection of a chondroinductive growth factor mixture (GFM). RESULTS:Histomorphological analysis showed complete osseointegration of all grafts from six weeks. The periosteum remained in place in 35 of 36 cases. Fibrocartilagineous repair tissue formation occurred at the cambium layer with a maximum at 12 weeks in both groups. Histomorphological grading and biomechanical testing showed highest values at 12 weeks, with signs of tissue degradation at one year. There was no significant difference between both groups. CONCLUSION:Transplantation of autologous osteoperiosteal grafts is an effective method to restore subchondral bone defects, but not the overlying cartilage as the repair tissue deteriorates in the long term. Subperiosteal growth factors injection did not stimulate tissue differentiation on a biomechanical and histomorphological level.

journal_name

Int Orthop

journal_title

International orthopaedics

authors

Gotterbarm T,Breusch SJ,Vilei SB,Mainil-Varlet P,Richter W,Jung M

doi

10.1007/s00264-013-1827-3

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

1171-8

issue

6

eissn

0341-2695

issn

1432-5195

journal_volume

37

pub_type

杂志文章

相关文献

INTERNATIONAL ORTHOPAEDICS文献大全
  • [Malunion of the distal radius and its treatment. Apropos of 122 radii].

    abstract：:We have reviewed 109 out of 122 operations performed for malunion of the distal radius. An excellent or good result was achieved in 80%, with 3% poor and 7% mediocre. Complications occurred in 12.6%. Accurate assessment of the frontal and sagittal angles of the articular surface of the distal radius was necessary in p...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/BF00182984

    authors： Sennwald G,Fischer W,Stähelin A

    更新日期：1992-01-01 00:00:00

  • A cementless hip system with a new surface for osseous integration.

    abstract：PURPOSE:The failure of total hip systems caused by wear-particle-induced loosening has focused interest on factors potentially affecting wear rate. Remnants of the blasting material were reported on grit-blasted surfaces for cementless fixation. These particles are believed to cause third-body wear and implant loosenin...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-013-2135-7

    authors： Lass R,Kolb A,Skrbensky G,Reinisch G,Kubista B,Giurea A,Windhager R,Kotz R

    更新日期：2014-04-01 00:00:00

  • A 4-year study of the mycological aspects of Kashin-Beck disease in Tibet.

    abstract：:In order to clarify the association between mycotoxin-producing fungi in food and Kashin-Beck disease (KBD), we examined the occurrence and contamination levels of fungi in samples of barley grain, from KBD-affected families and from unaffected families in endemic areas. A control area without the occurrence of KBD se...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s002640000218

    authors： Chasseur C,Suetens C,Michel V,Mathieu F,Begaux F,Nolard N,Haubruge E

    更新日期：2001-01-01 00:00:00

  • Healing of osteotomy sites applying either piezosurgery or two conventional saw blades: a pilot study in rabbits.

    abstract：PURPOSE:The purpose of this study was to compare bone healing of experimental osteotomies applying either piezosurgery or two different oscillating saw blades in a rabbit model. METHODS:The 16 rabbits were randomly assigned into four groups to comply with observation periods of one, two, three and five weeks. In all a...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-013-1908-3

    authors： Ma L,Stübinger S,Liu XL,Schneider UA,Lang NP

    更新日期：2013-08-01 00:00:00

  • Partial weightbearing is not necessary after cementless total hip arthroplasty: a two-year prospective randomized study on 100 patients.

    abstract：:The purpose of this study was to evaluate the effects of partial and full weightbearing after cementless total hip arthroplasty over a two year follow-up period. Fifty-nine women and 41 men (average age 61 years) received an uncemented Spotorno stem and were randomised into a full and a partial weightbearing group. No...

    journal_title：International orthopaedics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s00264-010-1089-2

    authors： Markmiller M,Weiss T,Kreuz P,Rüter A,Konrad G

    更新日期：2011-08-01 00:00:00

  • Assessment and management of chronic pain in patients with stable total hip arthroplasty.

    abstract：:Total hip arthroplasty (THA) is one of the most successful operations that can restore function and relieve pain. Although a majority of the patients achieve significant pain relief after THA, there are a number of patients that develop chronic pain for unknown reasons. A literature search was performed looking for ch...

    journal_title：International orthopaedics

    pub_type： 杂志文章,评审

    doi：10.1007/s00264-012-1711-6

    authors： Classen T,Zaps D,Landgraeber S,Li X,Jäger M

    更新日期：2013-01-01 00:00:00

  • Periprosthetic fractures with extensive bone loss treated with onlay strut allografts.

    abstract：:We reviewed a consecutive series of 19 patients with comminuted periprosthetic fractures, loosening of the femoral stem (Vancouver type B3) and significant loss of bone stock (Paprosky type III and IV). Sixteen porous-coated long stems and three Exeter stems, all with impaction grafting, were used. Large femoral onlay...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-002-0423-8

    authors： Barden B,von Knoch M,Fitzek JG,Löer F

    更新日期：2003-01-01 00:00:00

  • Tuberculous osteomyelitis. A review of 125 cases.

    abstract：:One hundred and twenty-five cases of tuberculous osteomyelitis have been observed by the authors since 1968. The site of the lesion and the clinical and radiological findings have been analysed. The importance of accurate diagnosis by bacteriological and histological investigation is emphasized. Pitfalls in the differ...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/BF00266209

    authors： Martini M,Adjrad A,Boudjemaa A

    更新日期：1986-01-01 00:00:00

  • Effects of Kinesio taping compared to arterio-venous Impulse System™ on limb swelling and skin temperature after total knee arthroplasty.

    abstract：PURPOSE:It is an established fact that post-operative (p.o.) soft-tissue swelling and lymphoedema after total knee arthroplasty (TKA) have a major influence on the p.o. early functional outcome. Kinesio taping has a proven clinical effect in increasing lymph drainage. Despite the decades of experience gained and the as...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-016-3295-z

    authors： Windisch C,Brodt S,Röhner E,Matziolis G

    更新日期：2017-02-01 00:00:00

  • Pustular osteoarthropathy and its differential diagnosis.

    abstract：:A combination of costo-sterno-clavicular hyperostosis and palmo-plantar pustulosis, sometimes with hyperostotic spondylosis and spondylarthritis, is called pustular osteoarthropathy. In the Western hemisphere 40 cases have been reported and in the Far East the condition occurs more commonly. Five cases are described. ...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/BF00179705

    authors： Wetzel R,Gondolph-Zink B,Puhl W

    更新日期：1991-01-01 00:00:00

  • Viability of loose body fragments in osteochondritis dissecans of the knee. A series of cases.

    abstract：:The purpose of this study was to determine if the cartilage from loose osteochondral fragments remains viable. Five patients with OCD of the knee who had undergone surgical treatment (arthroscopic reduction and internal fixation of the loose body) were included. The average age of patients was 13 years (range 10-14 ye...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-010-0951-6

    authors： Pascual-Garrido C,Tanoira I,Muscolo DL,Ayerza MA,Makino A

    更新日期：2010-08-01 00:00:00

  • Retention of a well-fixed acetabular component in the setting of acetabular osteolysis.

    abstract：PURPOSE:The treatment strategy for pelvic osteolysis with a well-fixed acetabular component after total hip arthroplasty(THA) involves replacing the acetabular cup liner and femoral head, débriding osteolytic lesions, and grafting. METHODS:We investigated whether retention of a well-fixed acetabular component using th...

    journal_title：International orthopaedics

    pub_type： 信件

    doi：10.1007/s00264-011-1372-x

    authors： Kang P,Yang J,Zhou Z,Shen B,Pei F

    更新日期：2012-05-01 00:00:00

  • Results of lateral ankle ligament repair surgery in one hundred and nineteen patients: do surgical method and arthroscopy timing matter?

    abstract：PURPOSE:Ankle sprains are the most common athletic injury. One of five chronic lateral ankle instability patients will require surgery, making operative outcomes crucial. The purpose of this study is to determine if operative method influences failure and complication rates in chronic lateral ankle ligament repair surg...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-017-3617-9

    authors： Araoye I,De Cesar Netto C,Cone B,Hudson P,Sahranavard B,Shah A

    更新日期：2017-11-01 00:00:00

  • Computerised navigation of unicondylar knee prostheses: from primary implantation to revision to total knee arthroplasty.

    abstract：AIM:Computerized navigation of unicondylar knee arthroplasties (UKA) is not a widespread technique. The lifespan of a UKA depends on the quality of its implantation. We know that overcorrection leads to a rapid extension of the osteoarthritis to the opposite side of the knee and undercorrection to a rapid loosening or ...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-016-3293-1

    authors： Saragaglia D,Marques Da Silva B,Dijoux P,Cognault J,Gaillot J,Pailhé R

    更新日期：2017-02-01 00:00:00

  • Outcomes of shoulder arthroplasty in diabetic patients as assessed by peri-operative A1C.

    abstract：PURPOSE:Although diabetes mellitus (DM) has an adverse effect on complication rates in orthopaedic surgery, neither the effect of DM nor the association between haemoglobin A1C (HbA1C) and outcomes after shoulder arthroplasty (SA) has been studied. METHODS:A retrospective review of 406 SAs (70 HAs, 188 total shoulder ...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-018-3874-2

    authors： Statz JM,Wagner ER,Sperling JW,Cofield RH

    更新日期：2018-08-01 00:00:00

  • Chondromyxoid fibroma of the foot and ankle: 40 years' Scottish bone tumour registry experience.

    abstract：:Ten cases of histologically proven chondromyxoid fibroma (CMF) of the foot and ankle with a mean follow-up of 6.1 years were retrospectively reviewed using the Scottish Bone Tumour Registry. The patients' mean age was 19 years; there were six males and four females. The anatomical locations were five phalangeal, three...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-005-0046-y

    authors： Sharma H,Jane MJ,Reid R

    更新日期：2006-06-01 00:00:00

  • Long-standing unreduced dislocation of the knee. A case report.

    abstract：:We have successfully treated a middle aged woman with long-standing posterior dislocations of the knee, using two stage external fixation and arthrodesis. ...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s002640050259

    authors： Vicente-Guillen P,Figa-Mataró J,Coloma-Bellver J

    更新日期：1998-01-01 00:00:00

  • How much are radiological parameters related to clinical symptoms and function in osteoarthritis of the shoulder?

    abstract：:Loss of joint space, formation of osteophytes and deformation are common features of osteoarthritis. Little information exists about the radiological features of arthrosis in relation to clinical findings and the radiological appearance in degenerative shoulder joint disease especially with regard to decision making a...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-009-0846-6

    authors： Kircher J,Morhard M,Magosch P,Ebinger N,Lichtenberg S,Habermeyer P

    更新日期：2010-06-01 00:00:00

  • The effect of low dose diclofenac sodium administered locally on heterotopic bone formation in rats.

    abstract：:The effect of a low dose of diclofenac sodium, administered locally, on heterotopic bone formation in rats was investigated. Heterotopic bone was induced by implantation of demineralised bone matrix into the gluteal muscles. Diclofenac was released continuously for 2 weeks from micro-osmotic pumps for each demineralis...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/BF00178357

    authors： Risto O,Wahlström O,Abdiu A

    更新日期：1995-01-01 00:00:00

  • Neural arch tuberculosis: a morbid disease. Radiographic and computed tomographic findings.

    abstract：:We have reviewed the clinical features, together with the radiographs and computerised tomography, in 9 patients with tuberculosis of the vertebral body and neural arch. All presented with paraparesis or paraplegia. The morbidity associated with this disease is so serious that it is essential to have an accurate means...

    journal_title：International orthopaedics

    pub_type： 杂志文章,评审

    doi：10.1007/BF00179971

    authors： Solomon A,Sacks AJ,Goldschmidt RP

    更新日期：1995-01-01 00:00:00

  • Unipolar hemiarthroplasty versus bipolar hemiarthroplasty in the most elderly patients with displaced femoral neck fractures: a randomised, controlled trial.

    abstract：PURPOSE:Hemiarthroplasty (HA) is generally considered to be the treatment of choice in the most elderly patients with a displaced fracture of the femoral neck. However, there is inadequate evidence to support the choice between unipolar HA or bipolar HA. The primary aim of this study was to analyse the outcome regardin...

    journal_title：International orthopaedics

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00264-011-1213-y

    authors： Hedbeck CJ,Blomfeldt R,Lapidus G,Törnkvist H,Ponzer S,Tidermark J

    更新日期：2011-11-01 00:00:00

  • Cementless total hip arthroplasty in advanced tuberculosis of the hip.

    abstract：PURPOSE:The use of total hip arthroplasty (THA) to treat advanced tuberculous arthritis, particularly during the active phase, is challenging. The aim of this study was to evaluate the efficacy of cementless THA for advanced hip joint tuberculosis. METHODS:This study reviewed 32 patients (mean age at surgery, 49.4 yea...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-015-2997-y

    authors： Zeng M,Hu Y,Leng Y,Xie J,Wang L,Li M,Zhu J

    更新日期：2015-11-01 00:00:00

  • Medieval orthopaedic history in Germany: Hieronymus Brunschwig and Hans von Gersdorff.

    abstract：:Hans von Gerssdorff and Hieronymus Brunschwig, who flourished in Germany in the latter half of the fifteenth century, have both left early printed treatises on Surgery which give excellent woodcuts showing pictures of instruments, operations, and costumes, at the end of the medieval period. Hieronymus Brunschwig or Hi...

    journal_title：International orthopaedics

    pub_type： 传,历史文章,杂志文章

    doi：10.1007/s00264-015-2868-6

    authors： Hernigou P

    更新日期：2015-10-01 00:00:00

  • Inter-observer reliability in the assessment of heterotopic ossification: proposal of a combined classification.

    abstract：:We applied four published classifications for assessment of heterotopic ossification after total hip arthroplasty (Arcq, Brooker, DeLee and Della Valle [1, 2, 5, 6]. The average incidence of heterotopic ossification varied from 19.8% to 27.7%. The inter-observer reliability of the various classifications was determine...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-004-0603-9

    authors： Toom A,Fischer K,Märtson A,Rips L,Haviko T

    更新日期：2005-06-01 00:00:00

  • Accuracy of the correction obtained after tibial valgus osteotomy. Comparison of the use of the Hernigou table and the so-called classical method.

    abstract：INTRODUCTION:Medial valgus-producing tibial osteotomy (MVTO) is classically used to treat early medial femorotibial osteoarthritis. Long-term results depend on the mechanical femorotibial angle (HKA) obtained at the end of the procedure. A correction goal between 3 and 6° valgus is commonly accepted. Several planning m...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-020-04777-6

    authors： Nicolau X,Bonnomet F,Micicoi G,Eichler D,Ollivier M,Favreau H,Ehlinger M

    更新日期：2020-12-01 00:00:00

  • Post-operative pain control following arthroscopic rotator cuff repair: peri-articular injection versus interscalene brachial plexus block.

    abstract：PURPOSE:To compare post-operative pain relief with peri-articular injection (PI) versus interscalene brachial plexus block (IBPB) after arthroscopic rotator cuff repair (ARCR) surgery. METHODS:We retrospectively reviewed 121 consecutive patients undergoing ARCR surgery divided into two groups: the PI group and the IBP...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-018-4096-3

    authors： Saito M,Tsukada S,Fujita N,Rahman M,Morita W,Kitamura N,Tasaki A

    更新日期：2019-06-01 00:00:00

  • Use of intramedullary fibular strut graft: a novel adjunct to plating in the treatment of osteoporotic humeral shaft nonunion.

    abstract：:Humeral shaft fractures respond well to conservative treatment and unite without much problem. Since it is uncommon, there is not much discussion regarding the management of nonunion in the literature, and hence this is a challenge to the treating orthopaedic surgeon. Osteoporosis of the fractured bone and stiffness o...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-008-0596-x

    authors： Vidyadhara S,Vamsi K,Rao SK,Gnanadoss JJ,Pandian S

    更新日期：2009-08-01 00:00:00

  • Stability of the elevated fragment in tibial plateau fractures. A radiographic stereophotogrammetric study of postoperative healing.

    abstract：:Five cases of fracture of the lateral tibial condyle of the split-depression type were treated by elevation of the depressed fragment, bone grafting and cancellous bone screws. During the operation, tantalum markers were inserted into the depressed fragment and the tibial metaphysis for radiographic stereophotogrammet...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/BF00192467

    authors： Ryd L,Toksvig-Larsen S

    更新日期：1994-06-01 00:00:00

  • Diagnosing acute compartment syndrome-where have we got to?

    abstract：PURPOSE:Acute compartment syndrome is a condition whereby tissue ischaemia occurs due to increased pressure in a closed myofascial compartment. It is a surgical emergency, with rapid recognition and treatment-the keys to good outcomes. METHODS:The available literature on diagnostic aids was reviewed by one of the seni...

    journal_title：International orthopaedics

    pub_type： 杂志文章,评审

    doi：10.1007/s00264-019-04386-y

    authors： McMillan TE,Gardner WT,Schmidt AH,Johnstone AJ

    更新日期：2019-11-01 00:00:00

  • Impact of preoperative myocardial infarction on surgical outcomes in inpatient orthopaedic surgery.

    abstract：PURPOSE:The purpose of this study was to evaluate the impact of a preoperative myocardial infarction (MI) on outcomes of inpatient orthopaedic operations. METHODS:The National Surgical Quality Improvement Program database was used to identify patients who underwent common orthopaedic operations from 2006 to 2010. Pati...

    journal_title：International orthopaedics

    pub_type： 杂志文章

    doi：10.1007/s00264-013-2001-7

    authors： Lim S,Edelstein AI,Jain U,Puri L,Kim JY

    更新日期：2013-12-01 00:00:00