Abstract：
:The demographic and clinical characteristics of adults and children with lower extremity deep-vein thrombosis and/or pulmonary embolism (LE DVT/PE) may differ from those with abdominal vein thrombosis (abdominal VT). Abdominal VT can be a presenting sign of an underlying prothrombotic state, and its presence in the setting of known disease might have prognostic implications different from LE DVT/PE. This study describes clinical presentations of abdominal VT compared to LE DVT/PE in adults and children. We analysed prospectively-collected data from consecutive consenting patients enrolled in one of seven Centers for Disease Control and Prevention (CDC) funded Thrombosis and Hemostasis Network Centers from August 2003 to April 2011 to compare the demographic and clinical characteristics of adults and children with abdominal VT. Both adults and children with abdominal VT tended to be younger and have a lower body mass index (BMI) than those with LE DVT/PE. Of patients with abdominal VT, children were more likely to have inferior vena cava (IVC) thrombosis than adults. For adults with venous thromboembolism (VTE), relatively more women had abdominal VT than LE DVT/PE, while the proportions with LE DVT/PE and abdominal VT by sex were similar in children. Children with abdominal VT were more likely to have diagnosed inherited thrombophilia, while trauma was more common in children with LE DVT/PE. In conclusion, both children and adults with abdominal VT were younger with a lower BMI than those with LE DVT/PE. Significant differences exist between children and adults in respect to abdominal VT compared to LE DVT/PE.
journal_name
Thromb Haemostjournal_title
Thrombosis and haemostasisauthors
Landi D,Beckman MG,Shah NR,Bockenstedt P,Grant AM,Heit JA,Key NS,Kulkarni R,Manco-Johnson M,Moll S,Philipp CS,Andersen JC,Ortel TLdoi
10.1160/TH12-08-0568subject
Has Abstractpub_date
2013-04-01 00:00:00pages
625-32issue
4eissn
0340-6245issn
2567-689Xpii
12-08-0568journal_volume
109pub_type
杂志文章,多中心研究abstract：:Atrial fibrillation (AF) is a common complication of coronary artery bypass grafting (CABG). We sought to determine the diagnostic validity of plasma biomarkers of i) inflammation (marked by interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hs-CRP]), ii) extracellular matrix remodelling (matrix metalloprot...
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
pub_type： 杂志文章
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更新日期：1981-06-30 00:00:00
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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doi：
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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doi：
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journal_title：Thrombosis and haemostasis
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journal_title：Thrombosis and haemostasis
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