Abstract:
:Evaluating the prospects for 'personalized healthcare' has become topical at the 10-year anniversary of the first results from the Human Genome Project. The coincidence of this milestone with a period of global financial difficulty is unfortunate, but industry has signaled its willingness to invest in this new medical paradigm in order to address the problems of high drug candidate attrition as well as escalating healthcare and R&D costs. For diagnostics manufacturers, justifying the ever-growing costs of development without an appropriate framework to provide reasonable return on investment is extremely challenging. Regulators have made good progress in defining what will satisfy current regulatory mandates, but there is still far to go to create conditions that would stimulate investment. My personal perspective is that personalized healthcare represents a solution rather than a problem and herein I describe the bottlenecks slowing development of novel diagnostics from the perspective of a willing commercial stakeholder.
journal_name
Pharmacogenomicsjournal_title
Pharmacogenomicsauthors
Creeden Jdoi
10.2217/pgs.12.143subject
Has Abstractpub_date
2012-11-01 00:00:00pages
1651-9issue
14eissn
1462-2416issn
1744-8042journal_volume
13pub_type
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