Abstract：
OBJECTIVE:The objective of study is to evaluate the incidence of leptomeningeal carcinomatosis (LMC) in breast cancer patients with parenchymal brain metastases (PBM) and clinical risk factors for the development of LMC. METHODS:We retrospectively analyzed 27 patients who had undergone surgical resection (SR) and 156 patients with whole brain radiation therapy (WBRT) as an initial treatment for their PBM from breast cancer in our institution and compared the difference of incidence of LMC according to clinical factors. The diagnosis of LMC was made by cerebrospinal fluid cytology and/or magnetic resonance imaging. RESULTS:A total of 27 patients (14%) in the study population developed LMC at a median of 6.0 months (range, 1.0-50). Ten of 27 patients (37%) developed LMC after SR, whereas 17 of 156 (11%) patients who received WBRT were diagnosed with LMC after the index procedure. The incidence of LMC was significantly higher in the SR group compared with the WBRT group and the hazard ratio was 2.95 (95% confidence interval; 1.33-6.54, p<0.01). Three additional factors were identified in the multivariable analysis : the younger age group (<40 years old), the progressing systemic disease showed significantly increased incidence of LMC, whereas the adjuvant chemotherapy reduce the incidence. CONCLUSION:There is an increased risk of LMC after SR for PBM from breast cancer compared with WBRT. The young age (<40) and systemic burden of cancer in terms of progressing systemic disease without adjuvant chemotherapy could be additional risk factors for the development of LMC.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Jung JM,Kim S,Joo J,Shin KH,Gwak HS,Lee SHdoi
10.3340/jkns.2012.52.3.193subject
Has Abstractpub_date
2012-09-01 00:00:00pages
193-9issue
3eissn
2005-3711issn
1598-7876journal_volume
52pub_type
杂志文章abstract：:A 55-year-old female patient presented with lower back pain and neurogenic intermittent claudication and underwent L3-L4 posterolateral fusion. To prepare the bone fusion bed, the transverse process of L3 and L4 was decorticated with a drill. On the 9th post-operative day, the patient complained of a sudden onset of s...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2013.54.4.344
更新日期：2013-10-01 00:00:00
abstract：:Mild traumatic brain injury is common in elderly patients, many of whom are on anticoagulant. The common practice is to discharge these patients from the emergency room if the computed tomography (CT) of the brain is normal. However, a very small proportion of these patients may develop a life threatening intracranial...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2014.55.1.51
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:The aneurysm remnants rate was evaluated via three-dimensional digital subtraction angiography (3D-DSA) in the postoperative evaluation of clipped aneurysms. METHODS:Data on surgically clipped aneurysms of anterior circulation obtained via postoperative 3D-DSA from February 2007 to March 2009 were gathered. ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.47.3.185
更新日期：2010-03-01 00:00:00
abstract：:Percutaneous endoscopic gastrostomy tube placement is often performed in patients with a ventriculoperitoneal shunt and it has been accepted as a safe procedure. The authors report a case of a 50-year-old male who developed acute exacerbation of the hydrocephalus immediately after the percutaneous endoscopic gastrosto...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2014.56.4.361
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To investigate the feasibility of C1 lateral mass screw and C2 pedicle screw with polyaxial screw and rod system supplemented with miniplate for interlaminar fusion to treat various atlantoaxial instabilities. METHODS:After posterior atlantoaxial fixation with lateral mass screw in the atlas and pedicle scre...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.52.2.120
更新日期：2012-08-01 00:00:00
abstract：:Inflammatory pseudotumor is an uncommon lesion with unknown etiology characterized by sclerosing inflammation which clinically and radiographically mimics a neoplastic lesion. A 47-year-old man presented with sudden headache and dysarthria. Brain CT scan revealed a 2.6x2.2 cm sized, round, and hyperdense mass in the a...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2009.45.2.99
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:The objectives of the present study were to characterize the natural course of initially non-operated traumatic acute subdural hematoma (ASDH) and to identify the risk factors of hematoma progression. METHODS:Retrospective analysis was performed using sequential computed tomography (CT) images maintained in ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2013.54.3.211
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate whether (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) can be used to assess the therapeutic response of brain abscess. METHODS:A study was conducted on 10 consecutive patients with brain abscess. Magnetic resonance imaging (MRI) with diffuse-weighte...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.49.5.278
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to determine the association between the cerebrospinal fluid (CSF) biomarkers and inflammation, and the predictive value of these CSF biomarkers for subsequent shunt associated infection. METHODS:We obtained CSF samples from the patients with hydrocephalus during ventriculoperitoneal...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.51.6.328
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to identify the factors affecting the failure of trials (<50% pain reduction in pain for trial period) to improve success rate of spinal cord stimulation (SCS) trial. METHODS:A retrospective review of the failed trials (44 patients, 36.1%) among the patients (n=122) who underwent...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2008.43.2.85
更新日期：2008-02-01 00:00:00
abstract：:A true collision tumor is a rare entity composed of two histologically distinct neoplasms coinciding in the same organ. This paper reports a unique case of cerebral collision tumor consisting of two benign components. On the first hand, meningioma which is usually a benign lesion arising from the meningothelial cell i...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2015.0707.011
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of posterior implant rigidity on spinal kinematics at adjacent levels by utilizing a cadaveric spine model with simulated physiological loading. METHODS:Five human lumbar spinal specimens (L3 to S1) were obtained and checked for abnormalities. The fresh specimens were stripped of m...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2015.58.5.412
更新日期：2015-11-01 00:00:00
abstract：:A 65-year-old male presented with pain in his right medial calf. An imaging study revealed no acute lesions, and a diagnosis of saphenous neuralgia was made by a nerve conduction study. He received temporary pain relief with saphenous nerve blocks twice in a one-week interval. Pulsed radiofrequency neuromodulation red...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2013.54.2.136
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVE:This 2009-2011 nation-wide study of adult Koreans was aimed to provide characteristics, medical utilization states, and survival rates for newly diagnosed patients with primary nonmalignant and malignant spine tumors. METHODS:Data for patients with primary spine tumors were selected from the Korean Health In...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.0505.011
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:The potassium disturbance associated with thiopental continuous infusion in neurosurgical patients is well known. However, the effect of propofol continuous infusion on serum potassium levels has not been investigated extensively. METHODS:We reviewed the medical records of 60 consecutive patients who receive...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2015.57.3.197
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to investigate clinical characteristics, management methods and possible causes of intracranial fusiform aneurysm. METHODS:Out of a series of 2,458 intracranial aneurysms treated surgically or endovascularly, 22 patients were identified who had discrete fusiform aneurysms. Clin...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2008.44.3.116
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:The case fatality rate of nonlesional intracerebral hemorrhage (n-ICH) was high and not changed. Knowing the causes is important to their prevention; however, the reasons have not been studied. The aims of this study were to determine the cause of death, to improve the clinical outcomes. METHODS:We retrospec...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2014.55.1.1
更新日期：2014-01-01 00:00:00
abstract：:Only a few cases of anterior longitudinal ligament (ALL) injury related with retropharyngeal hematoma without fracture have previously been reported. The treatment of choice for retropharyngeal hematoma is generally considered to be conservative care, but we believe that early surgery of this pathology would be better...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2015.58.3.304
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:Several surgical procedures have been reported for the treatment of chronic subdural hematoma (CSDH). We compared the results of treatments for CSDH obtained from one burr-hole craniostomy with closed system drainage with or without irrigation, two burr-hole craniostomy with closed system drainage with irriga...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2009.46.3.210
更新日期：2009-09-01 00:00:00
abstract：:Intracranial extraskeletal myxoid chondrosarcoma is extremely rare, with only seven patients previously reported. We present a case report of a 21-year-old woman admitted for weakness in her right extremities and symptoms of increased intracranial pressure. Magnetic resonance imaging (MRI) revealed hydrocephalus and a...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2012.52.3.246
更新日期：2012-09-01 00:00:00
abstract：:Organized hematoma is a rare complication that can develop following gamma knife radiosurgery (GKS) for cerebral arteriovenous malformation (AVM). Here, we describe 5 patients with growing organized hematomas that developed from completely obliterated AVMs several years after GKS. The patients were 15, 16, 30, 36, and...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2015.58.1.83
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:Transfemoral catheter angiography (TFCA) is a basic procedure in neurovascular surgery with increasing importance in surgical and non-invasive treatments. Unfortunately, resident neurosurgeons have relatively few opportunities to perform TFCA in most institutions. We report a method developed in our hospital ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2013.54.2.81
更新日期：2013-08-01 00:00:00
abstract：:Fusiform aneurysms on the basilar artery (BA) trunk are rare. The microsurgical management of these aneurysms is difficult because of their deep location, dense collection of vital cranial nerves, and perforating arteries to the brain stem. Endovascular treatment is relatively easier and safer compared with microsurgi...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2013.53.4.235
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:The incidence of leptomeningeal dissemination from malignant glioma is rare, so the clinical features of this are not well documented yet. We attempted to determine the clinical features of leptomeningeal dissemination from malignant gliomas. METHODS:We retrospectively analyzed 11 cases of leptomeningeal dis...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.49.6.334
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:Discal cyst is rare and causes indistinguishable symptoms from lumbar disc herniation. The clinical manifestations and pathological features of discal cyst have not yet been completely known. Discal cyst has been treated with surgery or with direct intervention such as computed tomography (CT) guided aspirati...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.51.4.208
更新日期：2012-04-01 00:00:00
abstract：Objective:Chronic subdural hematoma is a common and relatively benign disease. However, recurrence is common after surgical treatment, and the recurrence rate varies from 5% to 33%. The aim of this study was to investigate the predictive factors for recurrence of chronic subdural hematoma. Methods:We analyzed data fro...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.1010.003
更新日期：2017-11-01 00:00:00
abstract：:Pleomorphic xanthoastrocytoma (PXA) has been considered as a low grade tumor of adolescents and young adults. Although this tumor often shows cystic component, the hemorrhage within the cyst is extremely rare. The authors report a rare case of cystic PXA with a hemorrhage within the cyst and the mural nodule in the le...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2007.42.5.410
更新日期：2007-11-01 00:00:00
abstract：:We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2013.54.6.528
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to evaluate neuroprotective effect of sacral neuromodulation in rat spinal cord injury (SCI) model in the histological and functional aspects. METHODS:Twenty-one female Sprague Dawley rats were randomly divided into 3 groups : the normal control group (CTL, n=7), the SCI with sha...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.52.6.509
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:Retrospective analysis to compare the effect and complication of epidural patient-controlled analgesia (epidural PCA) with intravenous patient-controlled analgesia (IV PCA) for the treatment of the post-operative pain after posterior lumbar instrumented fusion. METHODS:Sixty patients who underwent posterior ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.50.3.205
更新日期：2011-09-01 00:00:00
