Abstract:
OBJECTIVE:The aim of this study is to determine the association between the cerebrospinal fluid (CSF) biomarkers and inflammation, and the predictive value of these CSF biomarkers for subsequent shunt associated infection. METHODS:We obtained CSF samples from the patients with hydrocephalus during ventriculoperitoneal (VP) shunt operations. Twenty-two patients were enrolled for this study and divided into 3 groups: subarachnoid hemorrhage (SAH)-induced hydrocephalus, idiopathic normal pressure hydrocephalus (INPH) and hydrocephalus with a subsequent shunt infection. We analyzed the transforming growth factor-β1, tumor necrosis factor-α, vascular endothelial growth factor (VEGF) and total tau in the CSF by performing enzyme-linked immunosorbent assay. The subsequent development of shunt infection was confirmed by the clinical presentations, the CSF parameters and CSF culture from the shunt devices. RESULTS:The mean VEGF concentration (±standard deviation) in the CSF of the SAH-induced hydrocephalus, INPH and shunt infection groups was 236±138, 237±80 and 627±391 pg/mL, respectively. There was a significant difference among the three groups (p=0.01). Between the SAH-induced hydrocephalus and infection groups and between the INPH and infection groups, there was a significant difference of the VEGF levels (p<0.01). However, the other marker levels did not differ among them. CONCLUSION:The present study showed that only the CSF VEGF levels are associated with the subsequent development of shunt infection. Our results suggest that increased CSF VEGF could provide a good condition for bacteria that are introduced at the time of surgery to grow in the brain, rather than reflecting a sequel of bacterial infection before VP shunt.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Lee JH,Back DB,Park DH,Cha YH,Kang SH,Suh JKdoi
10.3340/jkns.2012.51.6.328subject
Has Abstractpub_date
2012-06-01 00:00:00pages
328-33issue
6eissn
2005-3711issn
1598-7876journal_volume
51pub_type
杂志文章abstract::Plasma cell granuloma is a tumor-like disease characterized by non-neoplastic polyclonal proliferation of plasma cells and other mononuclear cells. This disease occurs most frequently in the lung and upper respiratory tract, while the involvement of the central nervous system is very rare. A 44-year-old female patient...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.46.2.161
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:The aim of the study is to determine the efficacy of indocyanine green (ICG) videoangiography for confirmation of vascular anastomosis patency in both extracranial-intracranial and intracranial-intracranial bypasses. METHODS:Intraoperative ICG videoangiography was used as a surgical adjunct for 56 bypasses i...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2011.50.1.23
更新日期:2011-07-01 00:00:00
abstract::The stereotactic surgical target for dystonic tremor is the subject of ongoing debate. Targeting the subthalamic area using deep brain stimulation has been regaining interest as a therapy for various types of involuntary movements. We describe the efficacy of stimulation of the subthalamic area in a patient with intra...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.45.5.303
更新日期:2009-05-01 00:00:00
abstract:Objective:In Asians, kneeling and squatting are the postures that are most often induce common peroneal neuropathy. However, we could not identify a compatible compression site of the common peroneal nerve (CPN) during hyper-flexion of knees. To evaluate the course of the CPN at the popliteal area related with compress...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2018.0018
更新日期:2018-07-01 00:00:00
abstract::Only a few cases of anterior longitudinal ligament (ALL) injury related with retropharyngeal hematoma without fracture have previously been reported. The treatment of choice for retropharyngeal hematoma is generally considered to be conservative care, but we believe that early surgery of this pathology would be better...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2015.58.3.304
更新日期:2015-09-01 00:00:00
abstract::Alveolar soft part sarcoma (ASPS) with skull and brain metastases is extremely rare. A 53-year-old patient diagnosed as skull metastasis of ASPS visited our clinic complaining of an outgrowing scalp mass in spite of radiation therapy. Past medical history revealed that the patient had been diagnosed and treated for AS...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2012.52.1.55
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:Microvascular decompression (MVD) for hemifacial spasm (HFS) involving the vertebral artery (VA) can be technically challenging. We investigated the therapeutic effects of a bioglue-coated Teflon sling technique on the VA during MVD in 42 cases. METHODS:A bioglue-coated Teflon sling was crafted by the surgeo...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2016.59.5.505
更新日期:2016-09-01 00:00:00
abstract::Gas pseudocysts are a rare cause of lumbar radiculopathy and most symptomatic gas pseudocysts are found within the confines of the spinal canal. A gas pseudocyst in the foramen causing lumbar radiculopathy is very rare. We present a case of a 67-year-old woman suffering from severe pain in the right leg. Computed tomo...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2010.47.3.232
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:Spinal cord injury (SCI) is a very serious health problem, usually caused by a trauma and accompanied by elevated levels of inflammation indicators. Stem cell-based therapy is promising some valuable strategies for its functional recovery. Nestinpositive progenitor and/or stem cells (SC) isolated from pancrea...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2018.0035
更新日期:2019-03-01 00:00:00
abstract::Fusiform aneurysms on the basilar artery (BA) trunk are rare. The microsurgical management of these aneurysms is difficult because of their deep location, dense collection of vital cranial nerves, and perforating arteries to the brain stem. Endovascular treatment is relatively easier and safer compared with microsurgi...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2013.53.4.235
更新日期:2013-04-01 00:00:00
abstract::Oblique basal skull fractures resulting from lateral crushing injuries involving both clivus and occipital condyle are rare due to their deep locations. Furthermore, these fractures may present clinically with multiple cranial nerve injuries because neural exit routes are restricted in this intricate region. The autho...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2012.51.5.305
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:This 2009-2011 nation-wide study of adult Koreans was aimed to provide characteristics, medical utilization states, and survival rates for newly diagnosed patients with primary nonmalignant and malignant spine tumors. METHODS:Data for patients with primary spine tumors were selected from the Korean Health In...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2016.0505.011
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to assess the safety and efficacy of the dynamic stabilization system in the treatment of degenerative spinal diseases. METHODS:The study population included 20 consecutive patients (13 females, 7 males) with a mean age of 61+/-6.98 years (range 46-70) who underwent decompres...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2008.43.5.221
更新日期:2008-05-01 00:00:00
abstract::We present an extremely rare case of the atypical choroid plexus papilloma in an adult which developed at the trigone of right lateral ventricle. A 62-year-old woman presented with the history of intermittent and gradually progressive headache and left side hemiparesis for 6 months. The brain magnetic resonance image ...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.46.1.74
更新日期:2009-07-01 00:00:00
abstract::Organized hematoma is a rare complication that can develop following gamma knife radiosurgery (GKS) for cerebral arteriovenous malformation (AVM). Here, we describe 5 patients with growing organized hematomas that developed from completely obliterated AVMs several years after GKS. The patients were 15, 16, 30, 36, and...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2015.58.1.83
更新日期:2015-07-01 00:00:00
abstract::Congenital anomalies in arches of the atlas are rare, and are usually discovered incidentally. However, a very rare subgroup of patients with unique radiographic features is predisposed to transient quadriparesis after minor cervical or head trauma. A 46-year-old male presented with a 2-month history of tremor and hyp...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2011.49.3.178
更新日期:2011-03-01 00:00:00
abstract::A 65-year-old man who had lateral cervical disc herniation underwent cervical posterior laminoforaminotomy at C5-6 and C6-7 level right side. During the operation, there was no serious surgical bleeding event. After operation, he complained persistent right shoulder pain and neck pain. Repeated magnetic resonance imag...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2013.53.2.125
更新日期:2013-02-01 00:00:00
abstract::Spinal epidural hematoma is a rare complication associated with pain control procedures such as facet block, acupuncture, epidural injection, etc. Although it is an uncommon cause of acute myelopathy, and it may require surgical evacuation. We report four patients with epidural hematoma developed after pain control pr...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2010.48.3.281
更新日期:2010-09-01 00:00:00
abstract:Objective:Electrooculography (EOG) records eyeball movements as changes in the potential difference between the negatively charged retina and the positively charged cornea. We aimed to investigate whether reliable EOG waveforms can be evoked by electrical stimulation of the oculomotor and abducens nerves during skull b...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0179
更新日期:2020-12-23 00:00:00
abstract:OBJECTIVE:Complex aneurysms such as fusiform and very small aneurysms (< 3 mm) are challenging in neurovascular and endovascular surgery. Author reports follow-up results of 9 cases treated by sole stent technique with pertinent literature review. METHODS:A retrospective study was made of 9 patients who were treated b...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2009.46.6.545
更新日期:2009-12-01 00:00:00
abstract:Objective:This study aims to investigate the relationship between aneurysm wall enhancement and clinical rupture risks based on the magnetic resonance vessel wall imaging (MR-VWI) quantitative methods. Methods:One hundred and eight patients with 127 unruptured aneurysms were prospectively enrolled from Feburary 2016 t...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0144
更新日期:2020-12-29 00:00:00
abstract:Objective:To explore the correlation between the polymorphism of histone deacetylase 9 gene (rs1060499865, rs723296, rs957960) and ischemic stroke (IS) in Chinese Han population in Dali region. Methods:This study included 155 IS patients and 128 healthy physical examinees. TaqMan-polymerase chain reaction technology a...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0040
更新日期:2020-11-24 00:00:00
abstract::Traumatic brainstem hemorrhage after blunt head injury is an uncommon event. The most frequent site of hemorrhage is the midline rostral brainstem. The prognosis of these patients is poor because of its critical location. We experienced a case of traumatic brainstem hemorrhage. A 41-year-old male was presented with dr...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2009.45.3.176
更新日期:2009-03-01 00:00:00
abstract::In this report, we introduce an undetermined fibrous tumor with calcification occurring in the cerebellopontine angle (CPA). A 51-year-old woman was admitted with a short history of dizziness. Computed tomography and magnetic resonance images revealed a 2×2×2 cm sized mass at the left CPA which was round and calcified...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2010.48.2.173
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The diagnosis of insufficiency fractures of the sacrum in an elder population increases annually. Fractures show very different morphology. We aimed to classify sacral insufficiency fractures according to the position of cortical break and possible need for intervention. METHODS:Between January 1, 2008 and D...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2017.0188
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To examine the synergistic effects of both computer-assisted cognitive rehabilitation (CACR) and transcranial direct current stimulation (tDCS) on cognitive function in patients with stroke. METHODS:The current double-blind, sham-controlled study enrolled a total of 11 patients who were newly diagnosed with ...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2013.54.6.484
更新日期:2013-12-01 00:00:00
abstract::Surgical treatment of the degenerative disc disease has evolved from traditional open spine surgery to minimally invasive spine surgery including endoscopic spine surgery. Constant improvement in the imaging modality especially with introduction of the magnetic resonance imaging, it is possible to identify culprit deg...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章,评审
doi:10.3340/jkns.2017.0203.004
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The authors evaluated the accuracies and ease of use of several commonly used microanastomosis training models (synthetic tube, chicken wing, and living rat model). METHODS:A survey was conducted among neurosurgeons and neurosurgery residents at a workshop held in 2009 at the authors' institute. Questions ad...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2010.47.4.287
更新日期:2010-04-01 00:00:00
abstract::We report a rare case of pronator teres syndrome in a young female patient. She reported that her right hand grip had weakened and development of tingling sensation in the first-third fingers two months previous. Thenar muscle atrophy was prominent, and hypoesthesia was also examined on median nerve territory. The pro...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2014.55.5.296
更新日期:2014-05-01 00:00:00
abstract::Sacral insufficiency fractures are usually known to develop in elderly patients with osteoporosis without definite trauma history. It is difficult to diagnose the sacral insufficiency fracture at an early stage because lower lumbar diseases, concurrently or not, may also be presented with similar symptoms and signs. W...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2008.44.3.166
更新日期:2008-09-01 00:00:00