Emotional dysregulation in adult ADHD: What is the empirical evidence?

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is a commonly occurring behavioral disorder among children. Community-based physicians are often the primary providers of services for children with ADHD. A set of consensus guidelines has been published by the American Academy of Pediatrics that provides best-practice d...

journal_title：Expert review of neurotherapeutics

authors： Langberg JM,Brinkman WB,Lichtenstein PK,Epstein JN

更新日期：2009-04-01 00:00:00

abstract：:In different study populations, several studies have shown that modest C-reactive protein elevation, in the range of apparently healthy individuals, is a strong predictor of future vascular events. Willcox and colleagues summarize the epidemiological and clinical observations that have led to the enthusiastic suggesti...

journal_title：Expert review of neurotherapeutics

authors： Di Napoli M,Papa F

更新日期：2004-07-01 00:00:00

abstract：:Cortical spreading depression (CSD) has been at the center stage of migraine pathophysiology for approximately six decades. Reanalysis of CSD reveals several major unbridgeable gaps in this experimental neurophysiologic concept for migraine. Key phenotypic and pharmacological features of migraine challenge the assumed...

journal_title：Expert review of neurotherapeutics

authors： Gupta VK

更新日期：2009-11-01 00:00:00

abstract：:Introduction: Despite increased interest in the pharmacotherapy of bipolar disorder during pregnancy and the postpartum period, management of the disorder during these critical periods in a woman's life remains challenging.Areas covered: The authors review the effect of pregnancy and the postpartum period on the cours...

journal_title：Expert review of neurotherapeutics

authors： Sharma V,Sharma P,Sharma S

更新日期：2020-04-01 00:00:00

abstract：:An influence of climate upon cerebrovascular risk is both biologically plausible and supported by epidemiological evidence. These relationships are important as they could yield public health strategies to help protect the vulnerable from the increased death rates arising during extreme cold and heat waves. Change in ...

journal_title：Expert review of neurotherapeutics

authors： McArthur K,Dawson J,Walters M

更新日期：2010-02-01 00:00:00

abstract：:Background: Relatively little is known about the use of disease-modifying drugs (DMDs) for multiple sclerosis (MS) in the population-based universal healthcare setting. This study aimed to describe the characteristics of a population-based cohort with MS and their DMD exposure in four Canadian provinces. Methods: We i...

journal_title：Expert review of neurotherapeutics

authors： Ng HS,Zhu F,Kingwell E,Zhao Y,Yao S,Ekuma O,Svenson LW,Evans C,Fisk JD,Marrie RA,Tremlett H

更新日期：2021-01-01 00:00:00

abstract：:Research into what works in depression is in trouble. All treatments appear equally effective and what happens in research trials does not seem to translate into clinical practice or, to put it another way, clinical practice is not reflected in randomized controlled trials. We run the risk of designing cosmetic trials...

journal_title：Expert review of neurotherapeutics

authors： Hatcher S

更新日期：2006-01-01 00:00:00

abstract：:Cognitive dysfunction (CD) affects 40-65% of multiple sclerosis (MS) patients and can have a great functional impact. It can be detected in all the disease phenotypes from the early stages of the disease and tends to progress over time. Memory, complex attention, information processing speed and executive functions ar...

journal_title：Expert review of neurotherapeutics

authors： Amato MP,Zipoli V,Portaccio E

更新日期：2008-10-01 00:00:00

abstract：:Introduction: Cognitive impairment and behavioral disturbances are common findings in Parkinson's disease (PD). Despite initially being considered late complications of the disease, it is currently accepted that almost all PD patients will exhibit cognitive and behavioral abnormalities from the early and even the prem...

journal_title：Expert review of neurotherapeutics

authors： Martinez-Horta S,Horta-Barba A,Kulisevsky J

更新日期：2019-07-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of β-amyloid peptides and neurofibrilllary tangles in brain, resulting in neuronal death and loss of cognitive abilities. It has been hypothesized that longstanding psychological stress can result in neural degenerat...

journal_title：Expert review of neurotherapeutics

authors： Johansson L

更新日期：2014-02-01 00:00:00

abstract：:Epilepsy is the most common serious neurological disorder in the elderly after stroke and dementia. It may be more important for elderly people because it is intermittent and unpredictable. There is no reliable diagnostic test and so its diagnosis and management requires clinical acumen and experience. The situation i...

journal_title：Expert review of neurotherapeutics

authors： Johnston A,Smith PE

更新日期：2010-12-01 00:00:00

abstract：:Cerebral folate deficiency is defined as any neurological condition associated with low cerebrospinal fluid folate concentrations. It is becoming increasingly associated with several neurological diseases, either genetic or environmental. Treatment of cerebral folate deficiency by folate supplementation is generally e...

journal_title：Expert review of neurotherapeutics

authors： Molero-Luis M,Serrano M,O'Callaghan MM,Sierra C,Pérez-Dueñas B,García-Cazorla A,Artuch R

更新日期：2015-01-01 00:00:00

abstract：:This article proposes a revision of the historical evolution of the concepts of generalized anxiety disorder (GAD). Currently, Darwin's evolutionary theory is the hegemonic paradigm for modern science and influences research on mental disorders. Throughout the 20th Century, the editions of the Diagnostic and Statistic...

journal_title：Expert review of neurotherapeutics

authors： Coutinho FC,Dias GP,do Nascimento Bevilaqua MC,Gardino PF,Pimentel Rangé B,Nardi AE

更新日期：2010-08-01 00:00:00

abstract：:Alzheimer's disease (AD) is a prevalent and currently incurable brain disease whose impact will continue to rise as the population ages. With limited treatment options, a variety of experimental therapies are currently in clinical trials. EVP-6124 (encenicline) is an α7 nicotinic acetylcholine receptor partial agonist...

journal_title：Expert review of neurotherapeutics

authors： Deardorff WJ,Shobassy A,Grossberg GT

更新日期：2015-01-01 00:00:00

abstract：:Natalizumab is an α-4 integrin antagonist used for the treatment of relapsing multiple sclerosis (MS). Concerns with the drug have a risen owing to a heightened risk of progressive multifocal leukoencephalopathy, which has caused some physicians to interrupt or stop treatment altogether. The article under review evalu...

journal_title：Expert review of neurotherapeutics

authors： Schaaf SM,Pitt D,Racke MK

更新日期：2011-09-01 00:00:00

abstract：:The most successful approach for treating people with Alzheimer's disease to date has been by improving cholinergic transmission using cholinesterase inhibitors. Many of these drugs selectively inhibit acetylcholinesterase but some agents inhibit both acetylcholinesterase and butyrylcholinesterase. Recent evidence fro...

journal_title：Expert review of neurotherapeutics

authors： Tasker A,Perry EK,Ballard CG

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:Antipsychotics have long been the mainstay of treatment for agitation and psychosis in Alzheimer's disease. Despite their current use successive studies have shown that they only confer a modest benefit which must be balanced against their well-established serious side effects (extrapyramidal symptoms, str...

journal_title：Expert review of neurotherapeutics

authors： Creese B,Da Silva MV,Johar I,Ballard C

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:The role of EEG in neonatal seizure detection is well-established, being the multichannel video-EEG the gold standard. However, in the clinical practice often amplitude integrated EEG (aEEG) is used, in order to overcome the difficulties related to EEG use. Areas covered: An overview regarding neonatal sei...

journal_title：Expert review of neurotherapeutics

authors： Pisani F,Pavlidis E

更新日期：2018-02-01 00:00:00

abstract：:Developing new treatment strategies for acute ischemic stroke in the last twenty years has offered some important successes, but also several failures. Most trials of neuroprotective therapies have been uniformly negative to date. Recent research has reported how excitatory amino acids act as the major excitatory neur...

journal_title：Expert review of neurotherapeutics

authors： Tuttolomondo A,Pecoraro R,Arnao V,Maugeri R,Iacopino DG,Pinto A

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Multiple Sclerosis is a chronic inflammatory demyelinating disease that affects 2.5 million people in the world. NEDA (No evidence of disease Activity) -4 is a new concept related to absence of disease activity in the context of MS. It takes into account the following four parameters: relapses; disability ...

journal_title：Expert review of neurotherapeutics

authors： Matta AP,Nascimento OJ,Ferreira AC,Magalhães TN,Benevides TP,Kirmse A,Dib JG,Cal H,Orsini M,Araujo LM

更新日期：2016-11-01 00:00:00

abstract：:Clomipramine ushered in a new age of pharmacotherapy for obsessive-compulsive disorders, and it also facilitated our understanding of the biological aspects of obsessive-compulsive disorder, focusing on the serotonergic systems. The introduction of selective serotonin reuptake inhibitors has led to great progress in t...

journal_title：Expert review of neurotherapeutics

authors： Kamijima K,Aoki M

更新日期：2006-07-01 00:00:00

abstract：:Alzheimer's disease is an age-related dementia and its incidence is rising in developed countries as the population ages. Amyloid plaques and tau-rich neurofibrillary tangles are pathologic hallmarks of the disease. Treatment is symptomatic, consisting of compounds that block enzymatic acetylcholine degradation (acety...

journal_title：Expert review of neurotherapeutics

authors： Silverberg GD,Mayo M,Saul T,Carvalho J,McGuire D

更新日期：2004-01-01 00:00:00

abstract：:Management issues for patients with brain tumors include peritumoral edema, symptomatic seizures, venous thromboembolism, headache, pain, fatigue and neuropsychological complaints. Vasogenic edema is typically ameliorated with the lowest dose possible of corticosteroid. Seizures are managed with attention to additiona...

journal_title：Expert review of neurotherapeutics

authors： Daly FN,Schiff D

更新日期：2007-10-01 00:00:00

abstract：:Introduction: Chronic Tic Disorders and Tourette's Disorder (collectively referred to as TD) are characterized by sudden, rapid, and repetitive motor movements or vocalizations called tics. Children, adolescents, and adults with TD often experience co-occurring psychiatric symptoms and impairments in multiple domains....

journal_title：Expert review of neurotherapeutics

authors： Essoe JK,Grados MA,Singer HS,Myers NS,McGuire JF

更新日期：2019-11-01 00:00:00

abstract：:The term cervicogenic headache (CeH) describes a syndrome originating from the cervical spine. There are a variety of therapeutic approaches used for the management of CeH, but scientific evidence of their effectiveness is scarce. No medication drug has proven to be effective. The evidence for greater occipital nerve ...

journal_title：Expert review of neurotherapeutics

authors： Fernández-de-las-Peñas C,Cuadrado ML

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Cerebral amyloid angiopathy (CAA) is characterized by the pathologic deposition of amyloid-beta within cortical and leptomeningeal arteries, arterioles, capillaries and, in rare cases, the venules of the brain. It is often associated with the development of lobar intracerebral hemorrhages (ICHs) but may ca...

journal_title：Expert review of neurotherapeutics

authors： Weber SA,Patel RK,Lutsep HL

更新日期：2018-06-01 00:00:00

abstract：:With advances in stereotactic and neuroimaging techniques, various minimally invasive image-guided techniques have gained widespread acceptance in the field of neuro-oncology. Laser interstitial thermal therapy (LITT) is an image-guided technique that involves generation of high temperatures using a laser fiber, to ab...

journal_title：Expert review of neurotherapeutics

authors： Sharma M,Balasubramanian S,Silva D,Barnett GH,Mohammadi AM

更新日期：2016-01-01 00:00:00

abstract：:The increasing prevalence of chronic pain with its major societal impact and the escalating use of opioids in managing it, along with their misuse, abuse, associated fatalities and costs, are epidemics in modern medicine. Over the past two decades, multiple lessons have been learned addressing various issues of abuse....

journal_title：Expert review of neurotherapeutics

authors： Manchikanti L,Boswell MV,Hirsch JA

更新日期：2013-05-01 00:00:00

abstract：:Spasticity is a common complication of CNS injury and a cause of considerable discomfort and disability for the patient and difficulty for caregivers. It is estimated that over half a million people in the USA are affected by spasticity. In recent years, advances in the treatment of spasticity include the use of intra...

journal_title：Expert review of neurotherapeutics

authors： Sheean G

更新日期：2003-11-01 00:00:00

abstract：:Central nervous system idiopathic inflammatory demyelinating disorders are a heterogenous group of diseases that share inflammation and demyelination as key features. Although the exact pathophysiology remains to be fully unveiled, these conditions are challenging to clinicians who seek specific therapeutic options fo...

journal_title：Expert review of neurotherapeutics

authors： Khoshnam M,Freedman MS

更新日期：2012-09-01 00:00:00