A direct inhibitory effect of botulinum toxin type A on antral circular muscle contractility of guinea pig.

abstract：PURPOSE:Label adherence for non-vitamin K antagonist oral anticoagulants (NOACs) has not been well evaluated in Asian patients with non-valvular atrial fibrillation (AF). The present study aimed to assess label adherence for NOACs in a Korean AF population and to determine risk factors of off-label prescriptions of NOA...

journal_title：Yonsei medical journal

authors： Lee SR,Lee YS,Park JS,Cha MJ,Kim TH,Park J,Park JK,Lee JM,Kang KW,Shim J,Uhm JS,Kim J,Kim C,Kim JB,Park HW,Joung B,Choi EK

更新日期：2019-03-01 00:00:00

abstract：:The diagnostic and prognostic implication of exaggerated blood pressure response to exercise have been controversial, with opinions ranging from a benign process to a harbinger of potential cardiovascular morbidity. Endothelial dysfunction has been demonstrated in patients with atherosclerosis and as a risk factor for...

journal_title：Yonsei medical journal

authors： Chang HJ,Chung JH,Choi BJ,Choi TY,Choi SY,Yoon MH,Hwang GS,Shin JH,Tahk SJ,Choi BI

更新日期：2003-12-30 00:00:00

abstract：PURPOSE:Coronary artery spasm (CAS) and diabetes mellitus (DM) are implicated in endothelial dysfunction, and insulin resistance (IR) is a major etiological cause of type 2 DM. However, the association between CAS and IR in non-diabetic individuals has not been elucidated. The aim of the present study was to evaluate t...

journal_title：Yonsei medical journal

authors： Kang KW,Choi BG,Rha SW

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:Pathogenesis and treatment of spontaneous dissecting aneurysm of the intracranial vertebral artery (VA) remain controversial. This study was designed to provide management strategies and to improve management outcome in patients with these aneurysms. MATERIALS AND METHODS:Among a total of 1,990 patients treate...

journal_title：Yonsei medical journal

authors： Lee JW,Jung JY,Kim YB,Huh SK,Kim DI,Lee KC

更新日期：2007-06-30 00:00:00

abstract：PURPOSE:Pharmacological inhibition of mutant isocitrate dehydrogenase (IDH) reduces R-2-hydroxyglutarate (2-HG) levels and restores cellular differentiation in vivo and in vitro. The IDH2 inhibitor enasidenib (AG-221) has been approved by the FDA as a first-in-class inhibitor for the treatment of relapsed or refractory...

journal_title：Yonsei medical journal

authors： Kim Y,Jeung HK,Cheong JW,Song J,Bae SH,Lee JI,Min YH

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Information on the possible role of the ribosomal protein S15a (RPS15a) in gastric cancer is scarce. The aim of this study was to evaluate the impact of RPS15a gene expression on the growth and cell cycle of gastric cancer cells in vitro and in vivo. MATERIALS AND METHODS:RPS15a mRNA expression was examined in...

journal_title：Yonsei medical journal

authors： Shi D,Liu J

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:The objective of this study was to describe hand function in relation with gross motor function and subtype of spastic cerebral palsy and to investigate the relationships among gross motor function, bimanual performance, unimanual capacity and upper limb functional measures in children with spastic cerebral pal...

journal_title：Yonsei medical journal

authors： Park ES,Rha DW,Park JH,Park DH,Sim EG

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) as a treatment for patients with Kawasaki disease (KD) which was resistant to intravenous immunoglobulin (IVIG). PATIENTS AND METHODS:The patients who had persistent or recrudescent fever after treatment with IVIG were subse...

journal_title：Yonsei medical journal

authors： Lee TJ,Kim KH,Chun JK,Kim DS

更新日期：2008-10-31 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD), a common genetic disease, is characterized by the development of hypertension and end stage renal disease. An increase in the activity of the renin-angiotensin system, due to a renal ischemia caused by cyst expansion, contributes to the development of hypertension ...

journal_title：Yonsei medical journal

authors： Lee KB,Kim UK

更新日期：2003-08-30 00:00:00

abstract：PURPOSE:Cervical cancer is one of the most fatal diseases among women in under-developed countries. To improve cervical cancer treatment, discovery of new targets is needed. In this study, we investigated the expression of NUP210, miR-22, and Fas in cervical cancer tissues and their functions in cell cycle regulation. ...

journal_title：Yonsei medical journal

authors： Gu Q,Hou W,Liu H,Shi L,Zhu Z,Ye W,Ni X

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:This study aimed to compare the effects of ticagrelor and clopidogrel on early neointimal healing assessed with optical coherence tomography (OCT) after drug-eluting stent (DES) implantation in patients with acute myocardial infarction (AMI). MATERIALS AND METHODS:AMI patients were randomly assigned to either ...

journal_title：Yonsei medical journal

authors： Kim C,Kim BK,Hong SJ,Ahn CM,Kim JS,Ko YG,Choi D,Hong MK,Jang Y

更新日期：2018-07-01 00:00:00

abstract：:We report a case of an extremely rare neoplasm, malignant granular cell tumor (MGCT). The patient was a 21-year-old woman, who was 5 months pregnant. The tumor occurred in the retrotracheal space, extending from the level of the larynx to the thoracic inlet. In addition, there were multiple, variable-sized tumor nodul...

journal_title：Yonsei medical journal

authors： Yang SW,Hong SW,Cho MY,Kang SJ

更新日期：1999-02-01 00:00:00

abstract：:Gastric carcinogenesis has been studied in various aspects. Helicobacter pylori (Hp) infection and mutation of the p53 tumor suppressor gene have recently been argued to be important factors of gastric carcinogenesis. There have been many studies to determine the precise mechanism of how Hp is related to gastric cance...

journal_title：Yonsei medical journal

authors： Chang KH,Kwon JW,Kim BS,Hwang JH,Lee SK,Lee YC,Park HJ,Park IS,Kim HK

更新日期：1997-04-01 00:00:00

abstract：PURPOSE:This study determined the seroprevalence of herpes virus 2 in gravidas and the differences between herpes virus 2-infected and healthy gravidas. The need to screen gravidas for herpes virus 2 was also evaluated. MATERIALS AND METHODS:A retrospective analysis involving 500 gravidas who underwent herpes virus 2 ...

journal_title：Yonsei medical journal

authors： Kim ID,Chang HS,Hwang KJ

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:Spatial hearing refers to the ability to understand speech and identify sounds in various environments. We assessed the validity of the Korean version of the Spatial Hearing Questionnaire (K-SHQ). MATERIALS AND METHODS:We performed forward translation of the original English SHQ to Korean and backward translat...

journal_title：Yonsei medical journal

authors： Kong TH,Park YA,Bong JP,Park SY

更新日期：2017-07-01 00:00:00

abstract：:Microvascular endothelial cells from rat lungs were cultured in serum-free medium supplemented with an endothelial growth substance, insulin, hydrocortisone and so on. Five to seven days after plating, cultured cells formed a monolayer. They were identified as endothelial cells by morphology and by positive immunohist...

journal_title：Yonsei medical journal

authors： Kim NS,Kim SJ

更新日期：1991-12-01 00:00:00

abstract：:Chromobacterium violaceum is a gram negative straight rod, 0.8-1.2 by 2.5 to 6.0 m, which is motile by one polar flagella and one to four lateral flagella. The organism inhabits soil and water and is often found in semitropical and tropical climates. Infections in humans are rare. We report a case of infection caused ...

journal_title：Yonsei medical journal

authors： Kim MH,Lee HJ,Suh JT,Chang BS,Cho KS

更新日期：2005-10-31 00:00:00

abstract：PURPOSE:To describe the therapeutic effect and possibility of the ultra-early surgery for poor-grade aneurysmal subarachnoid hemorrhage (Hunt-Hess grades IV-V). MATERIALS AND METHODS:Nine cases with intracranial aneurysms, demonstrated by computed tomographic angiography (CTA), were treated by ultra-early surgery unde...

journal_title：Yonsei medical journal

authors： Pan JW,Zhan RY,Wen L,Tong Y,Wan S,Zhou YY

更新日期：2009-08-31 00:00:00

abstract：:Pathogenic bacteria have increasingly been resisting to antimicrobial therapy. Recently, resistance problem has been relatively much worsened in Gram-negative bacilli. Acinetobacter spp. are typical nosocomial pathogens causing infections and high mortality, almost exclusively in compromised hospital patients. Acineto...

journal_title：Yonsei medical journal

authors： Lee K,Yong D,Jeong SH,Chong Y

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and stability of the wrap-clipping methods as a reconstructive strategy in the treatment of unclippable cerebral aneurysms. MATERIALS AND METHODS:Twenty four patients who had undergone wrap-clipping microsurgery were retrospectively reviewed. Type and morphology of the treated aneurysm...

journal_title：Yonsei medical journal

authors： Kim YB,Hong CK,Chung J,Joo JY,Huh SK

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:Plasma levels of renin, angiotensin II and aldosterone are increased during normal pregnancy. However, these values in preeclampsia are decreased to nearly that of a nonpregnant subject, and vascular sensitivity to angiotensin II is increased. In preeclampsia, aldosterone is decreased less than rennin. Therefor...

journal_title：Yonsei medical journal

authors： Kim EH,Lim JH,Kim YH,Park YW

更新日期：2008-02-29 00:00:00

abstract：:We report herein successful rigid bronchoscopy with preserved spontaneous breathing of a 54-day-old infant with tracheal web associated with previous ventricular septal defect (VSD) repair. We considered the use of dexmedetomidine in conjunction with intermittent ketamine from the following three clinical aspects. Fir...

journal_title：Yonsei medical journal

authors： Lee JS,Park SJ,Min KT

更新日期：2014-03-01 00:00:00

abstract：:Left atrial appendage (LAA) occlusion can be employed as an alternative treatment to oral anticoagulation in patients with atrial fibrillation to prevent embolic events. Atrial septal defect (ASD) may be related with right heart dysfunction and allow paradoxical embolism to occur. However, occlusion of both LAA throug...

journal_title：Yonsei medical journal

authors： Song S,Lee OH,Kim JS,Cho IJ,Shim CY,Hong GR,Pak HN,Jang Y

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:Recurrence rate is considered a better measure of clinical outcomes after thymoma resection than overall survival due to the indolent behavior of thymomas. This study was designed to determine predictors of recurrence after thymoma resection. MATERIALS AND METHODS:A single-institution, retrospective study was ...

journal_title：Yonsei medical journal

authors： Bae MK,Lee CY,Lee JG,Park IK,Kim DJ,Yang WI,Chung KY

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:Here, we compared the operative and perioperative outcomes between robot-assisted laparoscopic myomectomy (RALM) and abdominal myomectomy (AM) in patients with large (>10 cm) or heavy myomas (>250 g). MATERIALS AND METHODS:We included 278 patients who underwent multi-port RALM (n=126) or AM (n=151) for large o...

journal_title：Yonsei medical journal

authors： Lee SR,Lee ES,Lee YJ,Lee SW,Park JY,Kim DY,Kim SH,Kim YM,Suh DS,Kim YT

更新日期：2020-12-01 00:00:00

abstract：:A 71-year-old man was stable on warfarin (2.25 mg daily) therapy with an international normalized ratio (INR) of 1.8-2.2 after a heart valve replacement surgery. Recently, he consumed the liquid-like herbal product called shengmai-yin (10 mL daily) against medical advice. Seven days after the daily consumption of shen...

journal_title：Yonsei medical journal

authors： Su Q,Li Y

更新日期：2010-09-01 00:00:00

abstract：:We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerab...

journal_title：Yonsei medical journal

authors： Park KH,Yun IS,Choi SY,Lee JH,Hong CS,Park JW

更新日期：2013-01-01 00:00:00

abstract：:Pseudoaneurysm arising from the superficial temporal artery (STA) is very rare and is most commonly caused by blunt trauma. Most pseudoaneurysms of the STA usually present as a painless pulsating mass, with concomitant symptoms according to location, and their size may rapidly increase. The treatment of choice is liga...

journal_title：Yonsei medical journal

authors： Choo MJ,Yoo IS,Song HK

更新日期：1998-04-01 00:00:00

abstract：:The inactivation of p53 and p105RB by viral proteins or by mutations plays a key role in the oncogenesis of cervical carcinoma. The E6 and E7 proteins of HPV type 16 can bind to p53 and p105RB tumor suppressor gene products, respectively. In the present study, we tested a simple in vivo model that could explain the in...

journal_title：Yonsei medical journal

authors： Kim KH,Park TK,Yoon DJ,Kim YS

更新日期：1995-07-01 00:00:00

abstract：:Coronary-subclavian steal through the left internal mammary graft is a rare cause of myocardial ischemia in patients who have had a coronary bypass surgery. We report a 70-year-old man who presented with sustained monomorphic ventricular tachycardia 5 years after the surgical creation of a left internal mammary to the...

journal_title：Yonsei medical journal

authors： Kursaklioglu H,Kose S,Iyisoy A,Amasyali B,Celik T,Aytemir K,Isik E

更新日期：2009-12-31 00:00:00