Abstract:
STUDY DESIGN:Experimental measurement of bovine caudal annulus fibrosus (AF) biaxial stress-strain states for unloaded motion segments and those loaded in flexion combined with axial compression. OBJECTIVE:To measure AF biaxial stress-strain states for motion segments free of external loads and those loaded in flexion combined with axial compression. SUMMARY OF BACKGROUND DATA:In vitro, cyclically loaded flexion is associated with the complete rupture of the AF in acute cases. However, currently little is known about the tissue-level stress and strain states in this damaging load configuration. METHODS:Surface strains of the posterior annulus were measured, during loading of intact bovine caudal motion segments in flexion combined with axial compression, using the unloaded motion segment as a reference. Planar annulus specimens were excised from the motion segments, and the measured strains from the unloaded and flexed intact discs were applied to the excised specimens in a planar biaxial stress-strain device to determine the stress state in each condition. The annulus strain state of the flexed disc was input into a previously developed nonlinear strain energy function with additive terms that directly represent the structural features of the AF. RESULTS:The AF posterior surface strain for motion segments in flexion combined with compression was -0.1087 (circumferential) and 0.1051 (axial) on average. This strain state corresponded to average biaxial stresses in the annulus of 0.046 MPa (circumferential) and 0.224 MPa (axial). The planar AF specimens contracted after sectioning, resulting in small negative strains. In the absence of external loads on a motion segment, the annulus was approximately in a state of equibiaxial tensile stress. The theoretical analysis indicated that collagen crosslinks store a greater portion of the strain energy than the matrix or collagen fibers. CONCLUSION:In flexion combined with compression, the posterior AF stress state is biaxial and is much larger in the axial direction in bovine caudal discs.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Hollingsworth NT,Wagner DRdoi
10.1097/BRS.0b013e318259aa60subject
Has Abstractpub_date
2012-08-15 00:00:00pages
E1134-9issue
18eissn
0362-2436issn
1528-1159journal_volume
37pub_type
杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:A biomechanical cadaveric study of thoracic and lumbar vertebrae with simulated metastases quantifying intravertebral pressures during transpedicular vertebroplasty. OBJECTIVE:To compare intravertebral pressures during percutaneous vertebroplasty in vertebrae with and without simulated lytic metastases. ...
journal_title:Spine
pub_type: 杂志文章
doi:
更新日期:2003-07-15 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study OBJECTIVE.: To determine the rate of venous thromboembolism event (VTE) and risk factors for their occurrence in patients with vertebral fractures. SUMMARY OF BACKGROUND DATA:Deep vein thrombosis or pulmonary embolism (VTE) events are a significant source of potentially preventa...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002634
更新日期:2018-09-15 00:00:00
abstract:STUDY DESIGN:This is a single-center retrospective case-control study of 7 transfusion-related acute lung injury (TRALI) cases and 28 controls in the pediatric spinal surgery population. OBJECTIVE:To determine the association between maternal transfusion and risk of TRALI in pediatric spinal surgery patients. SUMMARY...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181e3dad2
更新日期:2010-11-01 00:00:00
abstract::Six patients with lumbar fractures were studied at the Pathokinesiology laboratory at Rancho Los Amigos Hospital following posterior Harrington distraction instrumentation to identify changes in posture and gait associated with iatrogenic loss of lumbar lordosis. Three patients, all with painful rods, were treated wit...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198307000-00007
更新日期:1983-07-01 00:00:00
abstract::Spinal cord evoked potentials were recorded from spinous processes of the lumbar, thoracic, and cervical levels of the spinal column of normal cats in response to direct stimulation of the sciatic nerve and subcutaneous stimulation of the posterior tibial nerve. The typical primary response was altered by changes in l...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-197911000-00007
更新日期:1979-11-01 00:00:00
abstract:STUDY DESIGN:Literature review of basic scientific and clinical research in spinal cord injury (SCI). OBJECTIVE:To provide physicians with an overview of the neurobiologic challenges of SCI, the current status of investigation for novel therapies that have been translated to human clinical trials, and the preclinical,...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e3181f3286d
更新日期:2010-10-01 00:00:00
abstract:STUDY DESIGN:A propensity score matching study. OBJECTIVE:The aim of this study was to assess the cost-effectiveness of balloon kyphoplasty (BKP) in Japan. SUMMARY OF BACKGROUND DATA:Osteoporotic vertebral fracture (OVF) is a common disease in elderly people. In Japan, the incidence of painful OVF in 2008 was estimat...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002829
更新日期:2019-03-01 00:00:00
abstract:STUDY DESIGN:A systematic review and meta-analysis. OBJECTIVE:To assess the measurement properties of the Functional Rating Index (FRI) and determine whether its measurement properties are comparable with other region-specific questionnaires. SUMMARY OF BACKGROUND DATA:In addition to low back pain (LBP) and neck pain...
journal_title:Spine
pub_type: 杂志文章,meta分析
doi:10.1097/BRS.0000000000002690
更新日期:2018-11-15 00:00:00
abstract:STUDY DESIGN:An observational prospective study. OBJECTIVE:The study objective was to assess the reliability and validity of the French-Canadian version (FCSSSQ) of the Swiss Spinal Stenosis questionnaire (SSSQ). SUMMARY OF BACKGROUND DATA:The SSSQ is a validated disease-specific tool developed to assess pain, functi...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002896
更新日期:2019-04-15 00:00:00
abstract::Somatosensory evoked potentials (SEPs) and neurogenic-motor evoked potentials (NMEPs) were recorded after overdistraction of the spinal cord at T5-T6, T12-L1, or L3-L4. Measures of spinal cord perfusion and clinical status were also administered. Results indicated that stiffer spinal segments allowed less distraction ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199009000-00003
更新日期:1990-09-01 00:00:00
abstract:STUDY DESIGN:Retrospective analysis. OBJECTIVE:We set out to evaluate the radiographic and patient-reported outcomes following C1-C2 arthrodesis for atlantoaxial osteoarthritis (AAOA) using modern instrumentation and techniques. SUMMARY OF BACKGROUND DATA:Few studies have evaluated outcomes following C1-C2 arthrodesi...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001783
更新日期:2017-03-01 00:00:00
abstract:STUDY DESIGN:Using a rat spondylosis model, the distributions of cells expressing the basic fibroblast growth factor and its receptor were investigated in normal and degenerated intervertebral discs. Cell-proliferating activity in degenerated discs was also assessed. OBJECTIVES:This study was conducted to determine wh...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199509150-00002
更新日期:1995-09-15 00:00:00
abstract:OBJECTIVE:To summarize the clinical manifestations and treatment of acquired hemophilia A in a patient with lumbar disc herniation. SUMMARY OF BACKGROUND DATA:Acquired hemophilia A is a rare but potentially life-threatening hemorrhagic disorder. It is caused by the development of autoantibodies directed against coagul...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e31819740d6
更新日期:2009-04-15 00:00:00
abstract:STUDY DESIGN:A prospective multicenter cohort study. OBJECTIVE:To establish the relationship between preoperative quantitative magnetic resonance imaging (MRI) parameters and clinical presentation and postoperative outcomes in patients with cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA:Correlation of ma...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/BRS.0000000000000436
更新日期:2014-08-15 00:00:00
abstract:STUDY DESIGN:A comparison of the latencies and amplitudes of the somatosensory-evoked potential in different stages of scoliosis surgery. OBJECTIVES:To investigate the normal variability of the somatosensory-evoked potential at different stages of scoliosis surgery and to improve the reliability of spinal cord monitor...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199909010-00009
更新日期:1999-09-01 00:00:00
abstract:STUDY DESIGN:Prospective, 2-factor design. The first factor was the group with 2 levels, spine surgery and control. The second factor was timing with 3 levels, baseline, 1-week follow-up, and 6-week follow-up. OBJECTIVES:The purpose of this study was to assess changes in caloric requirements and the body's nutritional...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000134564.24874.10
更新日期:2004-08-15 00:00:00
abstract:STUDY DESIGN:Case report and review of relevant literature. OBJECTIVE:To report a rare complication of esophageal perforation in cervical fracture patient with progressive ankylosing spondylitis (AS) and review of relevant literature. SUMMARY OF BACKGROUND DATA:Esophageal perforation in cervical fracture is extremely...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0000000000001885
更新日期:2016-11-15 00:00:00
abstract::Changes in the macromolecular matrix of the intervertebral disc may predispose to biomechanical failure of the disc. Such changes would involve extracellular enzymes capable of altering the collagen and proteoglycan of the disc matrix. In this study, extracts from homogenates of both annuli fibrosi and nuclei pulposi ...
journal_title:Spine
pub_type: 杂志文章
doi:
更新日期:1982-05-01 00:00:00
abstract::When the published data on the radial disc bulge in relation to the axial compression of the motion segment are compared to a simple mechanical model, it follows that an axial inward bulge of the vertebral endplates should occur during compression. The model predicts that the disc height at its center should remain pr...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198311000-00007
更新日期:1983-11-01 00:00:00
abstract::During magnetic resonance imaging, a vast amount of digital data on anatomic structures is translated into images, which are then assessed subjectively. The development of an objective, sensitive method to directly assess the digital data would have clear benefits, particularly for clinical research on disc degenerati...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199401001-00014
更新日期:1994-01-15 00:00:00
abstract:STUDY DESIGN:This study was designed to determine whether Augment Bone Graft (Augment, Biomimetic Therapeutics, Inc., Franklin, TN) and Augment Injectable Bone Graft (Augment Injectable, Biomimetic Therapeutics, Inc., Franklin, TN), 2 combination devices comprising recombinant human platelet-derived growth factor-BB an...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31823b01dc
更新日期:2012-04-15 00:00:00
abstract:STUDY DESIGN:This prospective study includes normal control subjects and patients with focal lesions of the spinal cord investigated by transcranial magnetic stimulation. OBJECTIVES:To establish a stable method to elicit motor evoked potentials from cervical to lumbar segmental levels and to apply the method that woul...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199805010-00010
更新日期:1998-05-01 00:00:00
abstract::Cadaver bone for spinal fusion operations is as safe as autografts. The author's 35 years' experience using cadaver bone for interbody spinal fusion operations has led to the development of a simplified bone bank method. Unsterile bone removed from young, fresh cadavers is cut into appropriate sizes and shapes, washed...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198001000-00002
更新日期:1980-01-01 00:00:00
abstract:STUDY DESIGN:Retrospective population-based cohort analysis. OBJECTIVE:Given the lack of large-scale data on the use and efficacy of multimodal analgesia in spine fusion surgery, we conducted a population-based analysis utilizing the nationwide claims-based Premier Healthcare database. SUMMARY OF BACKGROUND DATA:Mult...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003320
更新日期:2020-05-01 00:00:00
abstract:STUDY DESIGN:A prospective longitudinal study with 1-year follow-up. SUMMARY OF BACKGROUND DATA:Little is known about the consequences of having back pain and the patterns underlying the decisions to use medical care. OBJECTIVES:The aim of this study is to describe care utilization for low back pain (LBP) and to inve...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000127188.58944.1e
更新日期:2004-06-15 00:00:00
abstract:STUDY DESIGN:Repeated measurements were made of surface postural angles registering the relative positions of the head and neck in photographs and of angles of the upper cervical vertebrae recorded in lateral cephalometric radiographs in the same subjects. For all registrations, subjects assumed the natural head rest p...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199804150-00015
更新日期:1998-04-15 00:00:00
abstract:STUDY DESIGN:A prospective cohort study. OBJECTIVE:To establish outcome measures for recovery and chronic pain for studies with patients who present with recent-onset acute low back pain (LBP) in primary care. SUMMARY OF BACKGROUND DATA:Among back pain researchers, no consensus exists about outcome definitions or how...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31820c01a6
更新日期:2011-12-15 00:00:00
abstract:STUDY DESIGN:Traumatic injury of the cervical spine was produced on human cadavers and evaluated with instability tests and radiographs. OBJECTIVE:To relate traumatic injuries of the cervical spine to instability and patterns of traumatic injury to different levels of impact energy. SUMMARY OF BACKGROUND DATA:Data fr...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199903010-00006
更新日期:1999-03-01 00:00:00
abstract:STUDY DESIGN:Retrospective multicenter database review. OBJECTIVE:The aim of this study was to evaluate national postoperative outcomes and hospital characteristics trends from 2001 to 2010 for advanced age CSM patients. SUMMARY OF BACKGROUND DATA:Recent studies show increases in US cervical spine surgeries and CSM d...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/BRS.0000000000001181
更新日期:2016-02-01 00:00:00
abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:The purpose of the study was to examine survival after surgery for a metastatic spinal tumor using prognostic factors in the new Katagiri score. SUMMARY OF BACKGROUND DATA:Surgery for spinal metastasis can improve quality of life and facilitate treatment of the primary canc...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003415
更新日期:2020-07-01 00:00:00