Prognostic Factors in the New Katagiri Scoring System After Palliative Surgery for Spinal Metastasis.


STUDY DESIGN:Retrospective study. OBJECTIVE:The purpose of the study was to examine survival after surgery for a metastatic spinal tumor using prognostic factors in the new Katagiri score. SUMMARY OF BACKGROUND DATA:Surgery for spinal metastasis can improve quality of life and facilitate treatment of the primary cancer. However, choice of therapy requires identification of prognostic factors for survival, and these may change over time due to treatment advances. The new Katagiri score for the prognosis of skeletal metastasis includes classification of the primary tumor site and the effects of chemotherapy and hormonal therapy. METHODS:The subjects were 201 patients (127 males, 74 females) who underwent surgery for spinal metastases at six facilities in the Nagoya Spine Group. Age at surgery, gender, follow-up, metastatic spine level, primary cancer, new Katagiri score (including primary site, visceral metastasis, laboratory data, performance status (PS), and chemotherapy) and survival were obtained from a prospectively maintained database. RESULTS:Posterior decompression (n = 29) and posterior decompression and fixation with instrumentation (n = 182) were performed at a mean age of 65.9 (range, 16-85) years. Metastasis was present in the cervical (n = 19, 10%), thoracic (n = 155, 77%), and lumbar (n = 26, 13%) spine, and sacrum (n = 1, 1%). In multivariate analysis, moderate growth (HR 2.95, 95% CI, 1.27-7.89, P < 0.01) and rapid growth (HR 4.71, 95% CI, 2.78-12.31, P < 0.01) at the primary site; nodular metastasis (HR 1.53, 95% CI, 1.07-3.85, P < 0.01) and disseminated metastasis (HR 2.94, 95% CI, 1.33-5.42, P < 0.01); and critical laboratory data (HR 3.15, 95% CI, 2.06-8.36, P < 0.01), and poor PS (HR 2.83, 95% CI, 1.67-4.77, P < 0.01) were significantly associated with poor survival. CONCLUSION:Accurate prognostic factors are important in deciding the treatment strategy in patients with spinal metastasis, and our identification of these factors may be useful for these patients. LEVEL OF EVIDENCE:3.


Spine (Phila Pa 1976)




Kobayashi K,Ando K,Nakashima H,Sato K,Kanemura T,Yoshihara H,Hirasawa A,Kato F,Ishiguro N,Imagama S




Has Abstract


2020-07-01 00:00:00
















  • Long adult deformity fusions to L5 and the sacrum. A matched cohort analysis.

    abstract:STUDY DESIGN:A matched cohort analysis of long adult deformity fusions according to distal fusion level (L5 vs. S1). OBJECTIVE.: To compare the results of long adult deformity fusions to either L5 or the sacrum in the presence of a "healthy" 5-1 disc using a matched cohort analysis. SUMMARY OF BACKGROUND DATA:For adul...


    pub_type: 杂志文章,评审


    authors: Edwards CC 2nd,Bridwell KH,Patel A,Rinella AS,Berra A,Lenke LG

    更新日期:2004-09-15 00:00:00

  • Acupuncture for chronic low back pain: a multicenter, randomized, patient-assessor blind, sham-controlled clinical trial.

    abstract:STUDY DESIGN:Multicenter, randomized, patient-assessor blind, sham-controlled clinical trial. OBJECTIVE:To investigate the efficacy of acupuncture treatment with individualized setting for reduction of bothersomeness in participants with chronic low back pain (cLBP). SUMMARY OF BACKGROUND DATA:Low back pain is one of...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Cho YJ,Song YK,Cha YY,Shin BC,Shin IH,Park HJ,Lee HS,Kim KW,Cho JH,Chung WS,Lee JH,Song MY

    更新日期:2013-04-01 00:00:00

  • Multiple extradural arachnoid cysts: report of two operated cousin cases.

    abstract:STUDY DESIGN:Report of 2 operated cousin cases of the multiple spinal extradural arachnoid cysts. OBJECTIVE:To report the operative findings of cousin cases of the multiple spinal extradural arachnoid cysts and analyze a genetic etiology with the pedigree of all family members. SUMMARY OF BACKGROUND DATA:Spinal extra...


    pub_type: 杂志文章


    authors: Yabuki S,Kikuchi S

    更新日期:2007-09-15 00:00:00

  • Atlantoaxial dislocation as the presenting symptom of ankylosing spondylitis.

    abstract::A 27-year-old woman presented with nontraumatic atlantoaxial dislocation that required a C1-C2 fusion. A comprehensive investigation initially failed to reveal any evidence of infectious or rheumatologic disease and she remained well for 3 1/2 years, at which time a diagnosis of ankylosing spondylitis was established....


    pub_type: 杂志文章


    authors: Hamilton MG,MacRae ME

    更新日期:1993-11-01 00:00:00

  • Anterior interbody fusion of the cervical spine with coralline hydroxyapatite.

    abstract:STUDY DESIGN:A nonrandomized, retrospective human study of patients requiring anterior discectomy and reconstruction from C3 to T1. The pattern of incorporation, presence or absence of disc space collapse, maintenance of correction, and clinical outcomes were considered. OBJECTIVE:To determine the efficacy of corallin...


    pub_type: 杂志文章


    authors: Thalgott JS,Fritts K,Giuffre JM,Timlin M

    更新日期:1999-07-01 00:00:00

  • The evidence for intraoperative neurophysiological monitoring in spine surgery: does it make a difference?

    abstract:OBJECTIVE:The objective of this article was to undertake a systematic review of the literature to determine whether IOM is able to sensitively and specifically detect intraoperative neurologic injury during spine surgery and to assess whether IOM results in improved outcomes for patients during these procedures. SUMMA...


    pub_type: 杂志文章,评审


    authors: Fehlings MG,Brodke DS,Norvell DC,Dettori JR

    更新日期:2010-04-20 00:00:00

  • Differentiation of intervertebral notochordal cells through live automated cell imaging system in vitro.

    abstract:STUDY DESIGN:We demonstrated the differentiation of notochordal cells by direct observation using a live automated cell imaging system. We also hypothesized that notochordal cells have characteristics of chondrocyte-like cells. OBJECTIVE:To determine characteristics of notochordal cells by matrix protein expression an...


    pub_type: 杂志文章


    authors: Kim JH,Deasy BM,Seo HY,Studer RK,Vo NV,Georgescu HI,Sowa GA,Kang JD

    更新日期:2009-11-01 00:00:00

  • Factors predicting the result of surgery for lumbar intervertebral disc herniation.

    abstract::The prospective study was undertaken to find out preoperative or perioperative factors predicting the results of the first surgery for lumbar disc herniation. The results were evaluated 1 and 6 months postoperatively using, in addition to the patient evaluation, indices for pain, activities of daily living (ADL), and ...


    pub_type: 杂志文章


    authors: Hurme M,Alaranta H

    更新日期:1987-11-01 00:00:00

  • Trauma to anomalous cervical spine.

    abstract::A case of aplastic arch of the atlas (Keller's type) with severe injury to the cervical spine is presented. The impact of the accident was intense enough to produce bony compression of the C7 vertebra, but no injury occurred to the neural elements in the upper cervical spine. The presence of the ligamentous apparatus ...


    pub_type: 杂志文章


    authors: Weisz GM

    更新日期:1983-04-01 00:00:00

  • Hydroxyapatite-Based Biomaterials Versus Autologous Bone Graft in Spinal Fusion: An In Vivo Animal Study.

    abstract:STUDY DESIGN:An in vivo study was designed to compare the efficacy of biomimetic magnesium-hydroxyapatite (MgHA) and of human demineralized bone matrix (HDBM), both dispersed in a mixture of biomimetic MgHA nanoparticles, with that of an autologous bone graft. OBJECTIVE:The objective of this study was to evaluate 2 ne...


    pub_type: 杂志文章


    authors: Bròdano GB,Giavaresi G,Lolli F,Salamanna F,Parrilli A,Martini L,Griffoni C,Greggi T,Arcangeli E,Pressato D,Boriani S,Fini M

    更新日期:2014-05-15 00:00:00

  • Transient blindness after lumbar epidural steroid injection: a case report and literature review.

    abstract:STUDY DESIGN:A case report of transient blindness after lumbar epidural steroids is presented. OBJECTIVE:To report the diagnosis and treatment of a case of blindness after administration of lumbar epidural steroids. SUMMARY OF BACKGROUND DATA:Nine previous cases of blindness after lumbar epidural injection for back p...


    pub_type: 杂志文章,评审


    authors: Young WF

    更新日期:2002-11-01 00:00:00

  • Minimally Invasive Surgery for Neuromuscular Scoliosis: Results and Complications in a Series of One Hundred Patients.

    abstract:STUDY DESIGN:A retrospective review. OBJECTIVE:To report the results of an alternative technique using a minimally invasive fusionless surgery. The originality is based on the progressive correction of the deformities with proximal and distal fixation and on the reliability of the pelvic fixation using iliosacral scre...


    pub_type: 杂志文章


    authors: Miladi L,Gaume M,Khouri N,Johnson M,Topouchian V,Glorion C

    更新日期:2018-08-01 00:00:00

  • An in vitro biotribological assessment of NUBAC, a polyetheretherketone-on-polyetheretherketone articulating nucleus replacement device: methodology and results from a series of wear tests using different motion profiles, test frequencies, and environment

    abstract:STUDY DESIGN:In vitro biotribological investigation. OBJECTIVE:To evaluate the wear resistance and long-term biodurability of NUBAC, a PEEK-on-PEEK articulating nucleus replacement device, using a series of wear tests with different motion profiles, test frequencies, and environmental conditions. SUMMARY OF BACKGROUN...


    pub_type: 杂志文章


    authors: Brown T,Bao QB,Kilpela T,Songer M

    更新日期:2010-07-15 00:00:00

  • Textiloma: A Case of Foreign Body Mimicking a Spinal Tumor.

    abstract:STUDY DESIGN:Case report OBJECTIVE.: To report a case of foreign body mimicking spinal tumor. SUMMARY OF BACKGROUND DATA:Gossypiboma or more broadly retained foreign object is a surgical complication resulting from foreign materials such as cotton or gauze pads and surgical sponge, accidentally left inside a patient's...


    pub_type: 杂志文章


    authors: Meshkini A,Salehpour F,Rezakhah A,Mirzaei F,Kazemzadeh M,Naseri Alavi SA

    更新日期:2017-11-01 00:00:00

  • Immunohistologic study of the ruptured intervertebral disc of the lumbar spine.

    abstract:STUDY DESIGN:This study analyzed immunohistological features of the extruded or sequestrated intervertebral disc of the lumbar spine. To clarify the pathogenesis of neovascularization, cells isolated from herniated disc were cultured and examined biologically. OBJECTIVES:The objectives of this study were to characteri...


    pub_type: 杂志文章


    authors: Doita M,Kanatani T,Harada T,Mizuno K

    更新日期:1996-01-15 00:00:00

  • Influence of screw augmentation in posterior dynamic and rigid stabilization systems in osteoporotic lumbar vertebrae: a biomechanical cadaveric study.

    abstract:STUDY DESIGN:Biomechanical cadaveric study. OBJECTIVE:To determine whether augmentation positively influence screw stability or not. SUMMARY OF BACKGROUND DATA:Implantation of pedicle screws is a common procedure in spine surgery to provide an anchorage of posterior internal fixation into vertebrae. Screw performance...


    pub_type: 杂志文章


    authors: Hoppe S,Loosli Y,Baumgartner D,Heini P,Benneker L

    更新日期:2014-03-15 00:00:00

  • American Society of Anesthesiologists' Status Association With Cost and Length of Stay in Lumbar Laminectomy and Fusion: Results From an Institutional Database.

    abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:The objective of this study was to characterize the costs associated with American Society of Anesthesiologists (ASA) class, and to determine the extent to which ASA status is a predictor of increased cost and LOS following lumbar laminectomy and fusion (LLF). SUMMAR...


    pub_type: 杂志文章


    authors: Bronheim RS,Caridi JM,Steinberger J,Hunter S,Neifert SN,Deutsch BC,DeMaria S Jr,Hermann L,Gal JS

    更新日期:2020-03-01 00:00:00

  • Risk Factors for Rapidly Progressive Neurological Deterioration in Cervical Spondylotic Myelopathy.

    abstract:STUDY DESIGN:A retrospective single-center study. OBJECTIVE:This study sought to clarify the risk factors and to evaluate the surgical outcome in patients with rapidly progressive cervical spondylotic myelopathy (rp-CSM). SUMMARY OF BACKGROUND DATA:CSM is a degenerative spine disease presenting a slow development of ...


    pub_type: 杂志文章


    authors: Takasawa E,Sorimachi Y,Iizuka Y,Tsunoda D,Mieda T,Iizuka H,Chikuda H

    更新日期:2019-06-15 00:00:00

  • Psychomotor speed and postural control in chronic low back pain patients A controlled follow-up study.

    abstract:STUDY DESIGN:Psychomotor speed (reaction time) and postural control (center point of force velocity) among healthy control volunteers and patients with chronic low back pain (LBP) were studied at the beginning of an active, functional, restoration back rehabilitation program and 5 months after the program. OBJECTIVES:...


    pub_type: 杂志文章


    authors: Luoto S,Taimela S,Hurri H,Aalto H,Pyykkö I,Alaranta H

    更新日期:1996-11-15 00:00:00

  • Evaluating the Minimal Clinically Important Difference of EQ-5D-3L in Patients With Degenerative Lumbar Spinal Stenosis: A Swiss Prospective Multicenter Cohort Study.

    abstract:STUDY DESIGN:Analysis of a prospective, multicenter cohort study. OBJECTIVE:The aim of our study was to compare thresholds of published minimal clinically important differences (MCID) for the three-level EuroQol-5D health survey (EQ-5D-3L) summary index (range -0.53 to 1.00) with our anchor-based estimate and evaluate...


    pub_type: 杂志文章,多中心研究


    authors: Burgstaller JM,Wertli MM,Ulrich NH,Pichierri G,Brunner F,Farshad M,Porchet F,Steurer J,Gravestock I,LSOS Study Group.

    更新日期:2020-09-15 00:00:00

  • Impact of Living With Scoliosis: A utility Outcome Score Assessment.

    abstract:STUDY DESIGN:Survey. OBJECTIVE:The aim of this study was to objectify the burden of adolescent idiopathic scoliosis (AIS) to better advocate for scoliosis care in the future. SUMMARY OF BACKGROUND DATA:AIS is a common spinal deformity that can affect individuals on many levels. Patients with big curves usually seek m...


    pub_type: 杂志文章


    authors: Aldebeyan S,Sinno H,Makhdom A,Ouellet JA,Saran N

    更新日期:2017-01-15 00:00:00

  • Tumor necrosis factor-immunoreactive cells and PGP 9.5-immunoreactive nerve fibers in vertebral endplates of patients with discogenic low back Pain and Modic Type 1 or Type 2 changes on MRI.

    abstract:STUDY DESIGN:Immunohistochemistry for tumor necrosis factor (TNF) and protein gene product (PGP) 9.5 in vertebral endplates of patients with discogenic low back pain and Modic Type 1 or Type 2 endplate changes on MRI. OBJECTIVES:To examine whether inflammatory cytokines and nerve in-growth into the vertebral endplate ...


    pub_type: 杂志文章


    authors: Ohtori S,Inoue G,Ito T,Koshi T,Ozawa T,Doya H,Saito T,Moriya H,Takahashi K

    更新日期:2006-04-20 00:00:00

  • Cost-effectiveness of a Bone-anchored Annular Closure Device Versus Conventional Lumbar Discectomy in Treating Lumbar Disc Herniations.

    abstract:STUDY DESIGN:Cost-utility analysis of an annular closure device (ACD) based on data from a prospective, multicenter randomized controlled trial (RCT) OBJECTIVE.: The aim of this study was to determine the cost-effectiveness of a novel ACD in a patient population at high risk for recurrent herniation following discectom...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Ament J,Thaci B,Yang Z,Kulubya E,Hsu W,Bouma G,Kim KD

    更新日期:2019-01-01 00:00:00

  • Gait abnormalities arising from latrogenic loss of lumbar lordosis secondary to Harrington instrumentation in lumbar fractures.

    abstract::Six patients with lumbar fractures were studied at the Pathokinesiology laboratory at Rancho Los Amigos Hospital following posterior Harrington distraction instrumentation to identify changes in posture and gait associated with iatrogenic loss of lumbar lordosis. Three patients, all with painful rods, were treated wit...


    pub_type: 杂志文章


    authors: Hasday CA,Passoff TL,Perry J

    更新日期:1983-07-01 00:00:00

  • Major intraoperative neurologic deficits in pediatric and adult spinal deformity patients. Incidence and etiology at one institution.

    abstract:STUDY DESIGN:A retrospective study of 1,090 patients undergoing corrective spinal deformity surgery for scoliosis (n = 920), kyphosis (n = 77), or a combination of the two (n = 93) at one institution. OBJECTIVES:To ascertain the etiologies and incidence of neurologic deficits occurring at the time of surgery. SUMMARY...


    pub_type: 杂志文章


    authors: Bridwell KH,Lenke LG,Baldus C,Blanke K

    更新日期:1998-02-01 00:00:00

  • Key factors in back disability prevention: what influences the choice of priorities?

    abstract:STUDY DESIGN:Survey, subgroup analysis, Q-analysis, and analysis of e-mail exchanges. OBJECTIVE:To assess what influences the choice of priorities for interventions to prevent back-related disability. SUMMARY OF BACKGROUND DATA:Back-related disability results from interaction of physical, psychological, occupational,...


    pub_type: 杂志文章


    authors: Guzman J,Jones D,Cassidy JD,Furlan AD,Loisel P,Frank JW

    更新日期:2007-04-20 00:00:00

  • Results of a longer than 10-year follow-Up of patients with rheumatoid arthritis treated by occipitocervical fusion.

    abstract:STUDY DESIGN:Evaluation of results a longer than 10-year follow-up of patients with upper cervical lesions due to rheumatoid arthritis who underwent occipitocervical fusion. OBJECTIVE:To determine the final outcome of patients with upper cervical lesions due to rheumatoid arthritis treated by occipitocervical fusion. ...


    pub_type: 杂志文章


    authors: Matsunaga S,Ijiri K,Koga H

    更新日期:2000-07-15 00:00:00

  • Health-related quality of life and low back pain of patients surgically treated for scoliosis after 21 years or more of follow-up: comparison among nonidiopathic scoliosis, idiopathic scoliosis, and healthy subjects.

    abstract:STUDY DESIGN:A case-control study. OBJECTIVE:To compare health-related quality of life and low back pain of healthy subjects with those of patients with nonidiopathic scoliosis (non-IS) and idiopathic scoliosis (IS) 21 years or more after surgery. SUMMARY OF BACKGROUND DATA:There have been a very small number of repo...


    pub_type: 杂志文章


    authors: Akazawa T,Minami S,Kotani T,Nemoto T,Koshi T,Takahashi K

    更新日期:2012-10-15 00:00:00

  • Intraoperative waste in spine surgery: incidence, cost, and effectiveness of an educational program.

    abstract:STUDY DESIGN:Prospective observational study. OBJECTIVE:This study aims to quantify the incidence of intraoperative waste in spine surgery and to examine the efficacy of an educational program directed at surgeons to induce a reduction in the intraoperative waste. SUMMARY OF BACKGROUND DATA:Spine procedures are assoc...


    pub_type: 杂志文章


    authors: Soroceanu A,Canacari E,Brown E,Robinson A,McGuire KJ

    更新日期:2011-09-01 00:00:00

  • Direct Repair of Lumbar Pars Interarticularis Defects by Utilizing Intraoperative O-Arm-Based Navigation and Microendoscopic Techniques.

    abstract:STUDY DESIGN:A retrospective analysis of the clinical outcomes of eight patients with the lumbar pars interarticulars defects treated by direct repair with the aid of intraoperative O-arm based navigation and microendoscopic techniques. OBJECTIVE:The aim of this study was to investigate the efficacy and safety of dire...


    pub_type: 杂志文章


    authors: Jia M,Wang J,Zhang Z,Zheng W,Zhou Y

    更新日期:2016-10-01 00:00:00