当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Associative memory deficits in mild cognitive impairment: the role of hippocampal formation.

Associative memory deficits in mild cognitive impairment: the role of hippocampal formation.

Abstract：

:Neuropathological events featuring early stages of Alzheimer's disease (AD) appear in the entorhinal cortex (EC), subiculum (SB) and cornu ammonis 1 (CA1) of hippocampus, which may account for associative memory deficits in non-demented people with mild cognitive impairment (MCI). To test this hypothesis in vivo, we investigated whether volume changes in these regions are related to failures in associative memory in MCI as compared to cognitively normal (CN) elderly subjects. Volume changes in EC and hippocampal subfields were determined by using deformation-based morphometry techniques applied to probabilistic cytoarchitectonic maps derived from post mortem human brains. CN subjects were distinguished from MCI patients by firstly identifying local volume differences in EC and hippocampus, and then evaluating the way in which these anatomical changes correlated with performance in a non-intentional face-location association task. MCI patients not only performed worse than CN elders in building new associations, but they were further unable to benefit from semantic encoding to improve episodic binding. According to our initial hypothesis, local volume reductions in both EC and hippocampal CA accounted for group differences in associative memory whereas atrophy in CA, but not in EC, accounted for semantic encoding of associations. Two main conclusions can be drawn from the present study: i) access to semantic information during encoding does not reduce the episodic deficit in MCI; and ii) EC and hippocampal CA, two regions early affected by AD neuropathology, are responsible, at least partially, for associative memory deficits observed in MCI patients.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Atienza M,Atalaia-Silva KC,Gonzalez-Escamilla G,Gil-Neciga E,Suarez-Gonzalez A,Cantero JL

doi

10.1016/j.neuroimage.2011.05.047

subject

Has Abstract

pub_date

2011-08-15 00:00:00

pages

1331-42

issue

4

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(11)00555-6

journal_volume

57

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • Prospective motion correction of high-resolution magnetic resonance imaging data in children.

    abstract：:Motion artifacts pose significant problems for the acquisition and analysis of high-resolution magnetic resonance imaging data. These artifacts can be particularly severe when studying pediatric populations, where greater patient movement reduces the ability to clearly view and reliably measure anatomy. In this study,...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.06.017

    authors： Brown TT,Kuperman JM,Erhart M,White NS,Roddey JC,Shankaranarayanan A,Han ET,Rettmann D,Dale AM

    更新日期：2010-10-15 00:00:00

  • BDNF Val66Met polymorphism tunes frontolimbic circuitry during affective contextual learning.

    abstract：:Adaptive learning impairments are common in cognitive and behavioral disorders, but the neurogenetic mechanisms supporting human affective learning are poorly understood. We designed a higher-order contextual learning task in which healthy participants genotyped for the Val66Met polymorphism of the brain derived neuro...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.08.080

    authors： Jabbi M,Cropp B,Nash T,Kohn P,Kippenhan JS,Masdeu JC,Mattay R,Kolachana B,Berman KF

    更新日期：2017-11-15 00:00:00

  • Psychosocial stress is associated with in vivo dopamine release in human ventromedial prefrontal cortex: a positron emission tomography study using [¹⁸F]fallypride.

    abstract：:Rodent studies suggest that prefrontal dopamine neurotransmission plays an important role in the neural processing of psychosocial stress. Human studies investigating stress-induced changes in dopamine levels, however, have focused solely on striatal dopamine transmission. The aim of this study was to investigate in v...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.07.030

    authors： Lataster J,Collip D,Ceccarini J,Haas D,Booij L,van Os J,Pruessner J,Van Laere K,Myin-Germeys I

    更新日期：2011-10-15 00:00:00

  • Phonetic perceptual identification by native- and second-language speakers differentially activates brain regions involved with acoustic phonetic processing and those involved with articulatory-auditory/orosensory internal models.

    abstract：:This experiment investigates neural processes underlying perceptual identification of the same phonemes for native- and second-language speakers. A model is proposed implicating the use of articulatory-auditory and articulatory-orosensory mappings to facilitate perceptual identification under conditions in which the p...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.03.006

    authors： Callan DE,Jones JA,Callan AM,Akahane-Yamada R

    更新日期：2004-07-01 00:00:00

  • fMRI reflects functional connectivity of human somatosensory cortex.

    abstract：:Unilateral sensory stimulation reliably elicits contralateral somatotopic activation of primary (SI) and secondary (SII) somatosensory cortex. There is an ongoing debate about the occurrence and nature of concomitant ipsilateral SI and SII activation. Here we used functional magnetic resonance imaging (fMRI) in health...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.05.038

    authors： Blatow M,Nennig E,Durst A,Sartor K,Stippich C

    更新日期：2007-09-01 00:00:00

  • Topographic specificity of alpha power during auditory spatial attention.

    abstract：:Visual and somatosensory spatial attention both induce parietal alpha (8-14 ​Hz) oscillations whose topographical distribution depends on the direction of spatial attentional focus. In the auditory domain, contrasts of parietal alpha power for leftward and rightward attention reveal qualitatively similar lateralizatio...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116360

    authors： Deng Y,Choi I,Shinn-Cunningham B

    更新日期：2020-02-15 00:00:00

  • The brain and the stress axis: the neural correlates of cortisol regulation in response to stress.

    abstract：:The hypothalamic-pituitary-adrenal (HPA) axis is the major endocrine stress axis of the human organism. Cortisol, the final hormone of this axis, affects metabolic, cardiovascular and central nervous systems both acutely and chronically. Recent advances in neuroimaging techniques have led to the investigation of regul...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2009.05.074

    authors： Dedovic K,Duchesne A,Andrews J,Engert V,Pruessner JC

    更新日期：2009-09-01 00:00:00

  • Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans.

    abstract：:Surface EMG responses (MEPs) were recorded from the relaxed first dorsal interosseous (FDI) of 16 normal subjects following transcranial magnetic stimulation (TMS) over the hand area of the primary motor cortex. These test responses were conditioned by a subthreshold stimulus applied 2-15 ms beforehand over a range of...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.2001.0918

    authors： Civardi C,Cantello R,Asselman P,Rothwell JC

    更新日期：2001-12-01 00:00:00

  • Regional white matter volume differences in nondemented aging and Alzheimer's disease.

    abstract：:Accumulating evidence suggests that altered cerebral white matter (WM) influences normal aging, and further that WM degeneration may modulate the clinical expression of Alzheimer's disease (AD). Here we conducted a study of differences in WM volume across the adult age span and in AD employing a newly developed, autom...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.10.030

    authors： Salat DH,Greve DN,Pacheco JL,Quinn BT,Helmer KG,Buckner RL,Fischl B

    更新日期：2009-02-15 00:00:00

  • Patterns of effective connectivity during memory encoding and retrieval differ between patients with mild cognitive impairment and healthy older adults.

    abstract：:Previous research has shown that there is considerable overlap in the neural networks mediating successful memory encoding and retrieval. However, little is known about how the relevant human brain regions interact during these distinct phases of memory or how such interactions are affected by memory deficits that cha...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.10.002

    authors： Hampstead BM,Khoshnoodi M,Yan W,Deshpande G,Sathian K

    更新日期：2016-01-01 00:00:00

  • The 'Narcissus Effect': Top-down alpha-beta band modulation of face-related brain areas during self-face processing.

    abstract：:Self-related information, such as one's own face, is prioritized by our cognitive system. Whilst recent theoretical developments suggest that this is achieved by an interplay between bottom-up and top-down attentional mechanisms, their underlying neural dynamics are still poorly understood. Furthermore, it is still ma...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116754

    authors： Alzueta E,Melcón M,Jensen O,Capilla A

    更新日期：2020-06-01 00:00:00

  • Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans.

    abstract：:Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous opioids to exert its analgesic effect using [11C]diprenorphine (DPN) positron emission tomography (PET). Patients with de-afferentation pai...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.08.038

    authors： Sims-Williams H,Matthews JC,Talbot PS,Love-Jones S,Brooks JC,Patel NK,Pickering AE

    更新日期：2017-02-01 00:00:00

  • Friends, not foes: Magnetoencephalography as a tool to uncover brain dynamics during transcranial alternating current stimulation.

    abstract：:Brain oscillations are supposedly crucial for normal cognitive functioning and alterations are associated with cognitive dysfunctions. To demonstrate their causal role on behavior, entrainment approaches in particular aim at driving endogenous oscillations via rhythmic stimulation. Within this context, transcranial el...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.06.026

    authors： Neuling T,Ruhnau P,Fuscà M,Demarchi G,Herrmann CS,Weisz N

    更新日期：2015-09-01 00:00:00

  • Longitudinal analysis of gray and white matter loss in patients with systemic lupus erythematosus.

    abstract：:Cerebral atrophy has been described to occur in systemic lupus erythematosus (SLE) with variable frequency. The aim of this study was to determine white and gray matter abnormalities in brain magnetic resonance imaging (MRI) of patients with SLE and to determine if these abnormalities progress over a one-year period. ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.09.029

    authors： Appenzeller S,Bonilha L,Rio PA,Min Li L,Costallat LT,Cendes F

    更新日期：2007-01-15 00:00:00

  • The role of the medial wall and its anatomical variations for bimanual antiphase and in-phase movements.

    abstract：:The medial wall of the frontal cortex is thought to play an important role for bimanual coordination. However, there is uncertainty regarding the exact neuroanatomical regions involved. We compared the activation patterns related to bimanual movements using functional magnetic resonance imaging in 12 healthy right-han...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.2001.0856

    authors： Immisch I,Waldvogel D,van Gelderen P,Hallett M

    更新日期：2001-09-01 00:00:00

  • Real-time fMRI neurofeedback training to improve eating behavior by self-regulation of the dorsolateral prefrontal cortex: A randomized controlled trial in overweight and obese subjects.

    abstract：:Obesity is associated with altered responses to food stimuli in prefrontal brain networks that mediate inhibitory control of ingestive behavior. In particular, activity of the dorsolateral prefrontal cortex (dlPFC) is reduced in obese compared to normal-weight subjects and has been linked to the success of weight-loss...

    journal_title：NeuroImage

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.neuroimage.2019.02.033

    authors： Kohl SH,Veit R,Spetter MS,Günther A,Rina A,Lührs M,Birbaumer N,Preissl H,Hallschmid M

    更新日期：2019-05-01 00:00:00

  • Capturing the spatiotemporal dynamics of self-generated, task-initiated thoughts with EEG and fMRI.

    abstract：:The temporal structure of self-generated cognition is a key attribute to the formation of a meaningful stream of consciousness. When at rest, our mind wanders from thought to thought in distinct mental states. Despite the marked importance of ongoing mental processes, it is challenging to capture and relate these stat...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.03.029

    authors： Bréchet L,Brunet D,Birot G,Gruetter R,Michel CM,Jorge J

    更新日期：2019-07-01 00:00:00

  • Registration and machine learning-based automated segmentation of subcortical and cerebellar brain structures.

    abstract：:The large amount of imaging data collected in several ongoing multi-center studies requires automated methods to delineate brain structures of interest. We have previously reported on using artificial neural networks (ANN) to define subcortical brain structures. Here we present several automated segmentation methods u...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.05.063

    authors： Powell S,Magnotta VA,Johnson H,Jammalamadaka VK,Pierson R,Andreasen NC

    更新日期：2008-01-01 00:00:00

  • Learning piano melodies in visuo-motor or audio-motor training conditions and the neural correlates of their cross-modal transfer.

    abstract：:To investigate the cross-modal transfer of movement patterns necessary to perform melodies on the piano, 22 non-musicians learned to play short sequences on a piano keyboard by (1) merely listening and replaying (vision of own fingers occluded) or (2) merely observing silent finger movements and replaying (on a silent...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.03.038

    authors： Engel A,Bangert M,Horbank D,Hijmans BS,Wilkens K,Keller PE,Keysers C

    更新日期：2012-11-01 00:00:00

  • Decoded fMRI neurofeedback can induce bidirectional confidence changes within single participants.

    abstract：:Neurofeedback studies using real-time functional magnetic resonance imaging (rt-fMRI) have recently incorporated the multi-voxel pattern decoding approach, allowing for fMRI to serve as a tool to manipulate fine-grained neural activity embedded in voxel patterns. Because of its tremendous potential for clinical applic...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.neuroimage.2017.01.069

    authors： Cortese A,Amano K,Koizumi A,Lau H,Kawato M

    更新日期：2017-04-01 00:00:00

  • Intrinsic functional network architecture of human semantic processing: Modules and hubs.

    abstract：:Semantic processing entails the activation of widely distributed brain areas across the temporal, parietal, and frontal lobes. To understand the functional structure of this semantic system, we examined its intrinsic functional connectivity pattern using a database of 146 participants. Focusing on areas consistently a...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.03.004

    authors： Xu Y,Lin Q,Han Z,He Y,Bi Y

    更新日期：2016-05-15 00:00:00

  • Multivariate analysis of correlation between electrophysiological and hemodynamic responses during cognitive processing.

    abstract：:Animal and human studies have frequently shown that in primary sensory and motor regions the BOLD signal correlates positively with high-frequency and negatively with low-frequency neuronal activity. However, recent evidence suggests that this relationship may also vary across cortical areas. Detailed knowledge of the...

    journal_title：NeuroImage

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.neuroimage.2014.01.057

    authors： Kujala J,Sudre G,Vartiainen J,Liljeström M,Mitchell T,Salmelin R

    更新日期：2014-05-15 00:00:00

  • Perceptual similarity of visual patterns predicts dynamic neural activation patterns measured with MEG.

    abstract：:Perceptual similarity is a cognitive judgment that represents the end-stage of a complex cascade of hierarchical processing throughout visual cortex. Previous studies have shown a correspondence between the similarity of coarse-scale fMRI activation patterns and the perceived similarity of visual stimuli, suggesting t...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.02.019

    authors： Wardle SG,Kriegeskorte N,Grootswagers T,Khaligh-Razavi SM,Carlson TA

    更新日期：2016-05-15 00:00:00

  • Emotional conflict in interpersonal interactions.

    abstract：:Facial displays of emotions can help to infer the mental states of other individuals. However, the expectations we generate on the basis of people's emotions can mismatch their actual behaviour in certain circumstances, which generates conflict. In the present study, we explored the neural mechanisms of emotional conf...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.08.039

    authors： Ruz M,Tudela P

    更新日期：2011-01-15 00:00:00

  • EEG microstates as a tool for studying the temporal dynamics of whole-brain neuronal networks: A review.

    abstract：:The present review discusses a well-established method for characterizing resting-state activity of the human brain using multichannel electroencephalography (EEG). This method involves the examination of electrical microstates in the brain, which are defined as successive short time periods during which the configura...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2017.11.062

    authors： Michel CM,Koenig T

    更新日期：2018-10-15 00:00:00

  • Real-time feedback optimization of z-shim gradient for automatic compensation of susceptibility-induced signal loss in EPI.

    abstract：:Signal loss in gradient-echo echo planar imaging (GE-EPI) due to susceptibility-induced magnetic field inhomogeneity makes it difficult to assess the blood oxygenation level-dependent (BOLD) effect in fMRI investigations. The z-shim method that applies an additional gradient moment is one of the more popular methods o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.01.045

    authors： Tang YW,Huang TY

    更新日期：2011-04-15 00:00:00

  • Can visual information encoded in cortical columns be decoded from magnetoencephalography data in humans?

    abstract：:It is a principal open question whether noninvasive imaging methods in humans can decode information encoded at a spatial scale as fine as the basic functional unit of cortex: cortical columns. We addressed this question in five magnetoencephalography (MEG) experiments by investigating a columnar-level encoded visual ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.07.011

    authors： Cichy RM,Ramirez FM,Pantazis D

    更新日期：2015-11-01 00:00:00

  • A computational framework for the detection of subcortical brain dysmaturation in neonatal MRI using 3D Convolutional Neural Networks.

    abstract：:Deep neural networks are increasingly being used in both supervised learning for classification tasks and unsupervised learning to derive complex patterns from the input data. However, the successful implementation of deep neural networks using neuroimaging datasets requires adequate sample size for training and well-...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.05.049

    authors： Ceschin R,Zahner A,Reynolds W,Gaesser J,Zuccoli G,Lo CW,Gopalakrishnan V,Panigrahy A

    更新日期：2018-09-01 00:00:00

  • Self-feeding MUSE: a robust method for high resolution diffusion imaging using interleaved EPI.

    abstract：:Single-shot echo planar imaging (EPI) with parallel imaging techniques has been well established as the most popular method for clinical diffusion imaging, due to its fast acquisition and motion insensitivity. However, this approach is limited by the relatively low spatial resolution and image distortion. Interleaved ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.10.022

    authors： Zhang Z,Huang F,Ma X,Xie S,Guo H

    更新日期：2015-01-15 00:00:00

  • Supervoxel-based statistical analysis of diffusion tensor imaging in schizotypal personality disorder.

    abstract：:To study white matter changes in schizotypal personality disorder (SPD), we developed a new statistical analysis method based on supervoxels for diffusion tensor imaging. Twenty patients with SPD and eighteen healthy controls were recruited from a pool of 3000 first-year university undergraduates, and underwent MRI us...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.07.026

    authors： Zhang T,Wang D,Zhang Q,Wu J,Lv J,Shi L

    更新日期：2017-12-01 00:00:00