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Integrated biomarker responses as environmental status descriptors of a coastal zone (São Paulo, Brazil).

Abstract：

:São Paulo state (Brazil) has one of the most overpopulated coastal zones in South America, where previous studies have already detected sediment and water contamination. However, biological-based monitoring considering signals of xenobiotic exposure and effects are scarce. The present study employed a battery of biomarkers under field conditions to assess the environmental quality of this coastal zone. For this purpose, the activity of CYP 450, antioxidant enzymes, DNA damage, lipid peroxidation and lysosomal membrane were analysed in caged mussels and integrated using Factorial Analysis. A representation of estimated factor scores was performed in order to confirm the factor descriptions characterizing the studied areas. Biomarker responses indicated signals of mussels' impaired health during the monitoring, which pointed to the impact of different sources of contaminants in the water quality and identified critical areas. This integrated approach produced a rapid, sensitive and cost-effective assessment, which could be incorporated as a descriptor of environmental status in future coastal zones biomonitoring.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

Pereira CD,Martin-Díaz ML,Zanette J,Cesar A,Choueri RB,Abessa DM,Catharino MG,Vasconcellos MB,Bainy AC,de Sousa EC,Del Valls TA

doi

10.1016/j.ecoenv.2011.02.019

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

1257-64

issue

5

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(11)00062-5

journal_volume

74

pub_type

杂志文章

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