Moult cycle specific differential gene expression profiling of the crab Portunus pelagicus.

abstract：BACKGROUND:Retrogenes are processed copies of other genes. This duplication mechanism produces a copy of the parental gene that should not contain introns, and usually does not contain cis-regulatory regions. Here, we computationally address the evolutionary origin of promoter and other cis-regulatory regions in retrog...

journal_title：BMC genomics

authors： Bai Y,Casola C,Betrán E

更新日期：2008-05-22 00:00:00

abstract：BACKGROUND:Whole transcriptome analyses are an essential tool for understanding disease mechanisms. Approaches based on next-generation sequencing provide fast and affordable data but rely on the availability of annotated genomes. However, there are many areas in biomedical research that require non-standard animal mod...

journal_title：BMC genomics

authors： Schmucki R,Berrera M,Küng E,Lee S,Thasler WE,Grüner S,Ebeling M,Certa U

更新日期：2013-04-10 00:00:00

abstract：BACKGROUND:Grass carp (Ctenopharyngodon idella) belongs to the family Cyprinidae which includes more than 2000 fish species. It is one of the most important freshwater food fish species in world aquaculture. A linkage map is an essential framework for mapping traits of interest and is often the first step towards under...

journal_title：BMC genomics

authors： Xia JH,Liu F,Zhu ZY,Fu J,Feng J,Li J,Yue GH

更新日期：2010-02-24 00:00:00

abstract：BACKGROUND:Electron microscopy analyses of replicating chloroplast molecules earlier predicted bidirectional Cairns replication as the prevalent mechanism, perhaps followed by rounds of a rolling circle mechanism. This standard model is being challenged by the recent proposition of homologous recombination-mediated rep...

journal_title：BMC genomics

authors： Krishnan NM,Rao BJ

更新日期：2009-05-20 00:00:00

abstract：BACKGROUND:The importance of poultry as a global source of protein underpins the chicken genome and associated SNP data as key tools in selecting and breeding healthy robust birds with improved disease resistance. SNPs affecting host peptides involved in the innate defences tend to be rare, but three non-synonymous SNP...

journal_title：BMC genomics

authors： Cadwell K,Niranji SS,Armstrong VL,Mowbray CA,Bailey R,Watson KA,Hall J

更新日期：2017-08-18 00:00:00

abstract：BACKGROUND:The Bacillus cereus sensu lato group currently includes seven species (B. cereus, B. anthracis, B. mycoides, B. pseudomycoides, B. thuringiensis, B. weihenstephanensis and B. cytotoxicus) that recent phylogenetic and phylogenomic analyses suggest are likely a single species, despite their varied phenotypes. ...

journal_title：BMC genomics

authors： Scott E 2nd,Dyer DW

更新日期：2012-10-22 00:00:00

abstract：BACKGROUND:Single-cell gene expression measurements offer opportunities in deriving mechanistic understanding of complex diseases, including cancer. However, due to the complex regulatory machinery of the cell, gene regulatory network (GRN) model inference based on such data still manifests significant uncertainty. RE...

journal_title：BMC genomics

authors： Hajiramezanali E,Imani M,Braga-Neto U,Qian X,Dougherty ER

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:The measurement of gene expression using microarray technology is a complicated process in which a large number of factors can be varied. Due to the lack of standard calibration samples such as are used in traditional chemical analysis it may be a problem to evaluate whether changes done to the microarray pr...

journal_title：BMC genomics

authors： Bruland T,Anderssen E,Doseth B,Bergum H,Beisvag V,Laegreid A

更新日期：2007-10-18 00:00:00

abstract：BACKGROUND:Though Illumina has largely dominated the RNA-Seq field, the simultaneous availability of Ion Torrent has left scientists wondering which platform is most effective for differential gene expression (DGE) analysis. Previous investigations of this question have typically used reference samples derived from cel...

journal_title：BMC genomics

authors： Lahens NF,Ricciotti E,Smirnova O,Toorens E,Kim EJ,Baruzzo G,Hayer KE,Ganguly T,Schug J,Grant GR

更新日期：2017-08-10 00:00:00

abstract：BACKGROUND:The importance of Indian germplasm as origin and primary center of diversity of cultivated melon is widely accepted. Genetic diversity of several collections from Indian has been studied previously, although an integrated analysis of these collections in a global diversity perspective has not been possible. ...

journal_title：BMC genomics

authors： Gonzalo MJ,Díaz A,Dhillon NPS,Reddy UK,Picó B,Monforte AJ

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:Bixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L. An enzymatic pathway for bixin biosynthesis was inferred from homology of putative proteins encoded by differentially expressed seed cDNAs. Some activities we...

journal_title：BMC genomics

authors： Cárdenas-Conejo Y,Carballo-Uicab V,Lieberman M,Aguilar-Espinosa M,Comai L,Rivera-Madrid R

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:The approaches for shotgun-based sequencing of vertebrate genomes are now well-established, and have resulted in the generation of numerous draft whole-genome sequence assemblies. In contrast, the process of refining those assemblies to improve contiguity and increase accuracy (known as 'sequence finishing')...

journal_title：BMC genomics

authors： Blakesley RW,Hansen NF,Gupta J,McDowell JC,Maskeri B,Barnabas BB,Brooks SY,Coleman H,Haghighi P,Ho SL,Schandler K,Stantripop S,Vogt JL,Thomas PJ,NISC Comparative Sequencing Program.,Bouffard GG,Green ED

更新日期：2010-01-11 00:00:00

abstract：BACKGROUND:Genome-scale functional genomic screens across large cell line panels provide a rich resource for discovering tumor vulnerabilities that can lead to the next generation of targeted therapies. Their data analysis typically has focused on identifying genes whose knockdown enhances response in various pre-defin...

journal_title：BMC genomics

authors： Zhu Z,Ihle NT,Rejto PA,Zarrinkar PP

更新日期：2016-06-13 00:00:00

abstract：BACKGROUND:Increasing evidence has shown that circular RNAs (circRNAs) are involved in neurodegenerative disorders, but their roles in neurological toxoplasmosis are yet to know. This study examined miRNA and circRNA expressions in mouse brain following oral infection with T. gondii Pru strain. RESULTS:Total RNA extra...

journal_title：BMC genomics

authors： Zhou CX,Ai K,Huang CQ,Guo JJ,Cong H,He SY,Zhu XQ

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:Equine influenza is a major health problem of equines worldwide. The polymerase genes of influenza virus have key roles in virus replication, transcription, transmission between hosts and pathogenesis. Hence, the comprehensive genetic and codon usage bias of polymerase genes of equine influenza virus (EIV) w...

journal_title：BMC genomics

authors： Bera BC,Virmani N,Kumar N,Anand T,Pavulraj S,Rash A,Elton D,Rash N,Bhatia S,Sood R,Singh RK,Tripathi BN

更新日期：2017-08-23 00:00:00

abstract：BACKGROUND:Precise identification of three-dimensional genome organization, especially enhancer-promoter interactions (EPIs), is important to deciphering gene regulation, cell differentiation and disease mechanisms. Currently, it is a challenging task to distinguish true interactions from other nearby non-interacting o...

journal_title：BMC genomics

authors： Zeng W,Wu M,Jiang R

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Myostatin, a muscle-specific member of the Transforming Growth Factor beta family, negatively regulates muscle development. Double-muscled (DM) cattle have a loss-of-function mutation in their myostatin gene responsible for the hypermuscular phenotype. Thus, these animals are a good model for understanding t...

journal_title：BMC genomics

authors： Cassar-Malek I,Passelaigue F,Bernard C,Léger J,Hocquette JF

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Protein and mRNA levels for several selenoproteins, such as glutathione peroxidase-1 (Gpx1), are down-regulated dramatically by selenium (Se) deficiency. These levels in rats increase sigmoidally with increasing dietary Se and reach defined plateaus at the Se requirement, making them sensitive biomarkers for...

journal_title：BMC genomics

authors： Raines AM,Sunde RA

更新日期：2011-01-12 00:00:00

abstract：BACKGROUND:Oxidative stress caused by ground level ozone is a contributor to yield loss in a number of important crop plants. Soybean (Glycine max) is considered to be ozone sensitive, and current research into its response to oxidative stress is limited. To better understand the genetic response in soybean to oxidativ...

journal_title：BMC genomics

authors： Whaley A,Sheridan J,Safari S,Burton A,Burkey K,Schlueter J

更新日期：2015-06-04 00:00:00

abstract：BACKGROUND:It is widely known that castration has a significant effect on the accumulation of adipose tissue. microRNAs (miRNAs) are known to be involved in fat deposition and to be regulated by the androgen-induced androgen receptor (AR). However, there is little understanding of the relationship between miRNAs and fa...

journal_title：BMC genomics

authors： Bai Y,Huang JM,Liu G,Zhang JB,Wang JY,Liu CK,Fang MY

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:In livestock species like the chicken, high throughput single nucleotide polymorphism (SNP) genotyping assays are increasingly being used for whole genome association studies and as a tool in breeding (referred to as genomic selection). To be of value in a wide variety of breeds and populations, the success ...

journal_title：BMC genomics

authors： Groenen MA,Megens HJ,Zare Y,Warren WC,Hillier LW,Crooijmans RP,Vereijken A,Okimoto R,Muir WM,Cheng HH

更新日期：2011-05-31 00:00:00

abstract：BACKGROUND:Duplication, followed by fixation or random loss of novel genes, contributes to genome evolution. Particular outcomes of duplication events are possibly associated with pathogenic life histories in fungi. To date, differential gene gain and loss have not been studied at genomic scales in fungal pathogens, de...

journal_title：BMC genomics

authors： Powell AJ,Conant GC,Brown DE,Carbone I,Dean RA

更新日期：2008-03-28 00:00:00

abstract：BACKGROUND:Bacteroides thetaiotaomicron, a predominant member of the human gut microbiota, is characterized by its ability to utilize a wide variety of polysaccharides using the extensive saccharolytic machinery that is controlled by an expanded repertoire of transcription factors (TFs). The availability of genomic seq...

journal_title：BMC genomics

authors： Ravcheev DA,Godzik A,Osterman AL,Rodionov DA

更新日期：2013-12-12 00:00:00

abstract：BACKGROUND:The genome-wide association (GWA) approach represents an alternative to biparental linkage mapping for determining the genetic basis of trait variation. Both approaches rely on recombination to re-arrange the genome, and seek to establish correlations between phenotype and genotype. The major advantages of G...

journal_title：BMC genomics

authors： Cericola F,Portis E,Lanteri S,Toppino L,Barchi L,Acciarri N,Pulcini L,Sala T,Rotino GL

更新日期：2014-10-14 00:00:00

abstract：BACKGROUND:Banana and plantain (Musa spp.) comprise an important part of diets for millions of people around the globe. Low temperature is one of the key environmental stresses which greatly affects the global banana production. To understand the molecular mechanism of the cold-tolerance in plantain we used RNA-Seq bas...

journal_title：BMC genomics

authors： Yang QS,Gao J,He WD,Dou TX,Ding LJ,Wu JH,Li CY,Peng XX,Zhang S,Yi GJ

更新日期：2015-06-10 00:00:00

abstract：BACKGROUND:The membrane protein CD46, a ubiquitous cell surface pathogen receptor, can bind Streptococcus to trigger cell autophagy, which is a critical step in the control of infection. RESULTS:In this study, we found a new splice variant designated CD46 transcript variant (CD46-TV). The splice variant is characteriz...

journal_title：BMC genomics

authors： Wang X,Zhong J,Gao Y,Ju Z,Huang J

更新日期：2014-07-28 00:00:00

abstract：BACKGROUND:The programmed cell death 2 (Pdcd2) gene on mouse chromosome 17 was evaluated as a member of a highly conserved synteny, a candidate for an imprinted locus, and a candidate for the Hybrid sterility 1 (Hst1) gene. RESULTS:New mouse transcripts were identified at this locus: an alternative Pdcd2 mRNA skipping...

journal_title：BMC genomics

authors： Mihola O,Forejt J,Trachtulec Z

更新日期：2007-01-18 00:00:00

abstract：BACKGROUND:Human myelopoiesis is an exciting biological model for cellular differentiation since it represents a plastic process where multipotent stem cells gradually limit their differentiation potential, generating different precursor cells which finally evolve into distinct terminally differentiated cells. This stu...

journal_title：BMC genomics

authors： Ferrari F,Bortoluzzi S,Coppe A,Basso D,Bicciato S,Zini R,Gemelli C,Danieli GA,Ferrari S

更新日期：2007-08-03 00:00:00

abstract：BACKGROUND:After several years in the juvenile phase, trees undergo flowering transition to become mature (florally competent) trees. This transition depends on the balanced expression of a complex network of genes that is regulated by both endogenous and environmental factors. However, relatively little is known about...

journal_title：BMC genomics

authors： Zhang JZ,Ai XY,Sun LM,Zhang DL,Guo WW,Deng XX,Hu CG

更新日期：2011-01-26 00:00:00

abstract：BACKGROUND:Several in vitro studies document the function of the transcriptional regulator TrmBL1 of Pyrococcus furiosus. These data indicate that the protein can act as repressor or activator and is mainly involved in transcriptional control of sugar uptake and in the switch between glycolysis and gluconeogenesis. The...

journal_title：BMC genomics

authors： Reichelt R,Gindner A,Thomm M,Hausner W

更新日期：2016-01-08 00:00:00