Microarray profiling for differential gene expression in PMSG-hCG stimulated preovulatory ovarian follicles of Chinese Taihu and Large White sows.

abstract：BACKGROUND:The sequence of the pathogen Mycobacterium tuberculosis (Mtb) strain H37Rv has been available for over a decade, but the biology of the pathogen remains poorly understood. Genome sequences from other Mtb strains and closely related bacteria present an opportunity to apply the power of comparative genomics to...

journal_title：BMC genomics

authors： McGuire AM,Weiner B,Park ST,Wapinski I,Raman S,Dolganov G,Peterson M,Riley R,Zucker J,Abeel T,White J,Sisk P,Stolte C,Koehrsen M,Yamamoto RT,Iacobelli-Martinez M,Kidd MJ,Maer AM,Schoolnik GK,Regev A,Galagan J

更新日期：2012-03-28 00:00:00

abstract：BACKGROUND:With advances in next generation sequencing technology and analysis methods, single nucleotide variants (SNVs) and indels can be detected with high sensitivity and specificity in exome sequencing data. Recent studies have demonstrated the ability to detect disease-causing copy number variants (CNVs) in exome...

journal_title：BMC genomics

authors： Samarakoon PS,Sorte HS,Stray-Pedersen A,Rødningen OK,Rognes T,Lyle R

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:Chloroplasts have their own genomes, independent from nuclear genomes, that play vital roles in growth, which is a major targeted trait for genetic improvement in Populus. Angiosperm chloroplast genomes are maternally inherited, but the chloroplast' variation pattern of poplar at the single-base level during...

journal_title：BMC genomics

authors： Zhu S,Xu M,Wang H,Pan H,Wang G,Huang M

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:Thousands of intragenic long interspersed element 1 sequences (LINE-1 elements or L1s) reside within genes. These intragenic L1 sequences are conserved and regulate the expression of their host genes. When L1 methylation is decreased, either through chemical induction or in cancer, the intragenic L1 transcri...

journal_title：BMC genomics

authors： Wanichnopparat W,Suwanwongse K,Pin-On P,Aporntewan C,Mutirangura A

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:The green crab Carcinus maenas is known for its high acclimation potential to varying environmental abiotic conditions. A high ability for ion and acid-base regulation is mainly based on an efficient regulation apparatus located in gill epithelia. However, at present it is neither known which ion transport p...

journal_title：BMC genomics

authors： Fehsenfeld S,Kiko R,Appelhans Y,Towle DW,Zimmer M,Melzner F

更新日期：2011-10-06 00:00:00

abstract：BACKGROUND:The introduction of genome-wide shRNA and CRISPR libraries has facilitated cell-based screens to identify loss-of-function mutations associated with a phenotype of interest. Approaches to perform analogous gain-of-function screens are less common, although some reports have utilized arrayed viral expression ...

journal_title：BMC genomics

authors： Feddersen CR,Wadsworth LS,Zhu EY,Vaughn HR,Voigt AP,Riordan JD,Dupuy AJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:The relationships between parasitoids and their insect hosts have attracted attention at two levels. First, the basic biology of host-parasitoid interactions is of fundamental interest. Second, parasitoids are widely used as biological control agents in sustainable agricultural programs. Females of the grega...

journal_title：BMC genomics

authors： Fang Q,Wang L,Zhu J,Li Y,Song Q,Stanley DW,Akhtar ZR,Ye G

更新日期：2010-09-02 00:00:00

abstract：BACKGROUND:Horseradish peroxidases (HRPs) from Armoracia rusticana have long been utilized as reporters in various diagnostic assays and histochemical stainings. Regardless of their increasing importance in the field of life sciences and suggested uses in medical applications, chemical synthesis and other industrial ap...

journal_title：BMC genomics

authors： Näätsaari L,Krainer FW,Schubert M,Glieder A,Thallinger GG

更新日期：2014-03-24 00:00:00

abstract：BACKGROUND:Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that can be triggered through genetic or sporadic mechanisms. MicroRNAs (miRNAs) have become a major therapeutic focus as their pervasive expression and powerful regulatory roles in disease pathogenesis become increasingly a...

journal_title：BMC genomics

authors： Kocerha J,Kouri N,Baker M,Finch N,DeJesus-Hernandez M,Gonzalez J,Chidamparam K,Josephs KA,Boeve BF,Graff-Radford NR,Crook J,Dickson DW,Rademakers R

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:Excretory/secretory proteins (ESPs) play a major role in parasitic infection as they are present at the host-parasite interface and regulate host immune system. In case of parasitic helminths, transcriptomics has been used extensively to understand the molecular basis of parasitism and for developing novel t...

journal_title：BMC genomics

authors： Garg G,Ranganathan S

更新日期：2011-11-30 00:00:00

abstract：BACKGROUND:The sequential nature of gel-based marker systems entails low throughput and high costs per assay. Commonly used marker systems such as SSR and SNP are also dependent on sequence information. These limitations result in high cost per data point and significantly limit the capacity of breeding programs to obt...

journal_title：BMC genomics

authors： Mace ES,Xia L,Jordan DR,Halloran K,Parh DK,Huttner E,Wenzl P,Kilian A

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Synthetic systems that use positive feedback have been developed to control human disease vectors and crop pests. The tTAV system, which has been deployed in several insect species, relies on a positive feedback circuit that can be inhibited via dietary tetracycline. Although insects carrying tTAV fail to su...

journal_title：BMC genomics

authors： Bryk J,Reeves RG,Reed FA,Denton JA

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Dystonia1 (DYT1) dystonia is caused by a glutamic acid deletion (ΔE) mutation in the gene encoding Torsin A in humans (HTorA). To investigate the unknown molecular and cellular mechanisms underlying DYT1 dystonia, we performed an unbiased proteomic analysis. RESULTS:We found that the amount of proteins and ...

journal_title：BMC genomics

authors： Kim AY,Seo JB,Kim WT,Choi HJ,Kim SY,Morrow G,Tanguay RM,Steller H,Koh YH

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Whole-genome sequencing is an important method to understand the genetic information, gene function, biological characteristics and survival mechanisms of organisms. Sequencing large genomes is very simple at present. However, we encountered a hard-to-sequence genome of Pseudomonas aeruginosa phage PaP1. Sho...

journal_title：BMC genomics

authors： Lu S,Le S,Tan Y,Li M,Liu C,Zhang K,Huang J,Chen H,Rao X,Zhu J,Zou L,Ni Q,Li S,Wang J,Jin X,Hu Q,Yao X,Zhao X,Zhang L,Huang G,Hu F

更新日期：2014-09-19 00:00:00

abstract：BACKGROUND:Among viruses, bacteriophages are a group of special interest due to their capacity of infecting bacteria that are important for biotechnology and human health. Composting is a microbial-driven process in which complex organic matter is converted into humus-like substances. In thermophilic composting, the de...

journal_title：BMC genomics

authors： Amgarten D,Martins LF,Lombardi KC,Antunes LP,de Souza APS,Nicastro GG,Kitajima EW,Quaggio RB,Upton C,Setubal JC,da Silva AM

更新日期：2017-05-04 00:00:00

abstract：BACKGROUND:Parkinson's disease (PD) is the second most prevalent neurodegenerative disorders in the world. Studying PD from systems biology perspective involving genes and their regulators might provide deeper insights into the complex molecular interactions associated with this disease. RESULT:We have studied gene co...

journal_title：BMC genomics

authors： Chatterjee P,Roy D,Bhattacharyya M,Bandyopadhyay S

更新日期：2017-09-12 00:00:00

abstract：BACKGROUND:The complete sequences of chloroplast genomes provide wealthy information regarding the evolutionary history of species. With the advance of next-generation sequencing technology, the number of completely sequenced chloroplast genomes is expected to increase exponentially, powerful computational tools annota...

journal_title：BMC genomics

authors： Liu C,Shi L,Zhu Y,Chen H,Zhang J,Lin X,Guan X

更新日期：2012-12-20 00:00:00

abstract：BACKGROUND:Major changes in gene expression occur in the fetal brain to modulate the function of this organ postnatally. Thus, factors can alter the genomics of the fetal brain, predisposing to neurological disorders later in life. We hypothesized that the physiological dynamics of the immune system transcriptome of th...

journal_title：BMC genomics

authors： Rabaglino MB,Keller-Wood M,Wood CE

更新日期：2014-11-19 00:00:00

abstract：BACKGROUND:Identification of acute or recent hepatitis C virus (HCV) infections is important for detecting outbreaks and devising timely public health interventions for interruption of transmission. Epidemiological investigations and chemistry-based laboratory tests are 2 main approaches that are available for identifi...

journal_title：BMC genomics

authors： Lara J,Teka M,Khudyakov Y

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:The gene composition, gene order and structure of the mitochondrial genome are remarkably stable across bilaterian animals. Lice (Insecta: Phthiraptera) are a major exception to this genomic stability in that the canonical single chromosome with 37 genes found in almost all other bilaterians has been lost in...

journal_title：BMC genomics

authors： Cameron SL,Yoshizawa K,Mizukoshi A,Whiting MF,Johnson KP

更新日期：2011-08-04 00:00:00

abstract：BACKGROUND:Genetic resistance in cattle is considered a suitable way to control tick burden and its consequent losses for livestock production. Exploring tick-resistant (R) and tick-susceptible (S) hosts, we investigated the genetic mechanisms underlying the variation of Braford resistance to tick infestation. Skin bio...

journal_title：BMC genomics

authors： Moré DD,Cardoso FF,Mudadu MA,Malagó-Jr W,Gulias-Gomes CC,Sollero BP,Ibelli AMG,Coutinho LL,Regitano LCA

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:Cucumber, Cucumis sativus L. (2n = 2 × = 14) and melon, C. melo L. (2n = 2 × = 24) are two important vegetable species in the genus Cucumis (family Cucurbitaceae). Both species have an Asian origin that diverged approximately nine million years ago. Cucumber is believed to have evolved from melon through chr...

journal_title：BMC genomics

authors： Li D,Cuevas HE,Yang L,Li Y,Garcia-Mas J,Zalapa J,Staub JE,Luan F,Reddy U,He X,Gong Z,Weng Y

更新日期：2011-08-05 00:00:00

abstract：BACKGROUND:Chinese bayberry (Myrica rubra Sieb. and Zucc.) is a subtropical evergreen tree originating in China. It has been cultivated in southern China for several thousand years, and annual production has reached 1.1 million tons. The taste and high level of health promoting characters identified in the fruit in rec...

journal_title：BMC genomics

authors： Jiao Y,Jia HM,Li XW,Chai ML,Jia HJ,Chen Z,Wang GY,Chai CY,van de Weg E,Gao ZS

更新日期：2012-05-23 00:00:00

abstract：:Following the publication of the original article [1], the authors reported an error in Fig. 2 of the PDF version of their article. ...

journal_title：BMC genomics

authors： Maarsingh JD,Yang S,Park JG,Haydel SE

更新日期：2019-12-31 00:00:00

abstract：BACKGROUND:The question of whether bacterial species objectively exist has long divided microbiologists. A major source of contention stems from the fact that bacteria regularly engage in horizontal gene transfer (HGT), making it difficult to ascertain relatedness and draw boundaries between taxa. A natural way to defi...

journal_title：BMC genomics

authors： Wright ES,Baum DA

更新日期：2018-10-03 00:00:00

abstract：UNLABELLED:AB BACKGROUND: MicroRNAs (miRNAs) are small, non-coding 21-25 nt RNA molecules that play an important role in regulating gene expression. Little is known about the expression profiles and functions of miRNAs in skin and their role in pigmentation. Alpacas have more than 22 natural coat colors, more than any ...

journal_title：BMC genomics

authors： Tian X,Jiang J,Fan R,Wang H,Meng X,He X,He J,Li H,Geng J,Yu X,Song Y,Zhang D,Yao J,Smith GW,Dong C

更新日期：2012-10-16 00:00:00

abstract：BACKGROUND:Evolution leaves an imprint in species through genetic change. At the molecular level, evolutionary changes can be explored by studying ratios of nucleotide substitutions. The interplay among molecular evolution, derived phenotypes, and ecological ranges can provide insights into adaptive radiations. Caecili...

journal_title：BMC genomics

authors： Torres-Sánchez M,Gower DJ,Alvarez-Ponce D,Creevey CJ,Wilkinson M,San Mauro D

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Transmembrane β-barrel proteins are a special class of transmembrane proteins which play several key roles in human body and diseases. Due to experimental difficulties, the number of transmembrane β-barrel proteins with known structures is very small. Over the years, a number of learning-based methods have b...

journal_title：BMC genomics

authors： Tran Vdu T,Chassignet P,Sheikh S,Steyaert JM

更新日期：2012-04-12 00:00:00

abstract：BACKGROUND:The Abeta-binding alcohol dehydrogenase/17beta-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10) is an enzyme involved in pivotal metabolic processes and in the mitochondrial dysfunction seen in the Alzheimer's disease. Here we use comparative genomic analyses to study the evolution of the HADH2 gene encodin...

journal_title：BMC genomics

authors： Marques AT,Antunes A,Fernandes PA,Ramos MJ

更新日期：2006-08-09 00:00:00

abstract：BACKGROUND:Repeat masking is an important step in the EST analysis pipeline. For new species, genomic knowledge is scarce and good repeat libraries are typically unavailable. In these cases it is common practice to mask against known repeats from other species (i.e., model organisms). There are few studies that investi...

journal_title：BMC genomics

authors： Malde K,Jonassen I

更新日期：2008-01-18 00:00:00