Abstract:
BACKGROUND:Up to fifty percent of alcohol dependent individuals have alexithymia, a personality trait characterised by difficulties identifying and describing feelings, a lack of imagination and an externalised cognitive style. Although studies have examined alexithymia in relation to alcohol dependence, no research exists on mechanisms underlying this relationship. The present study examined the mediational effect of alcohol expectancies on alexithymia and alcohol dependence. METHODS:230 outpatients completed the Toronto Alexithymia Scale (TAS-20), the Drinking Expectancy Questionnaire (DEQ) and the Alcohol Use Disorder Identification Test (AUDIT). RESULTS:Regression analysis showed that alexithymia and alcohol dependence was, in two of three cases, partially mediated through alcohol expectancy. CONCLUSIONS:Alcohol expectancies of assertion and affective change show promise as mediators of alcohol dependence in individuals with alexithymia.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Thorberg FA,Young RM,Sullivan KA,Lyvers M,Hurst CP,Connor JP,Feeney GFdoi
10.1016/j.drugalcdep.2010.11.015subject
Has Abstractpub_date
2011-07-01 00:00:00pages
238-41issue
1-3eissn
0376-8716issn
1879-0046pii
S0376-8716(10)00411-4journal_volume
116pub_type
杂志文章abstract::A prospective double-blind placebo-controlled trial of intramuscular Naftidrofuryl was carried out on 32 randomly selected hospitalized male alcoholic patients with clinical, biochemical and histological evidence of hepatic damage. Seventeen patients received the drug (40 mg in 5 ml i.m. three times daily for 6 days) ...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0376-8716(82)90004-7
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:Despite the high rates of comorbidity of post-traumatic stress disorder (PTSD) and alcohol dependence (AD) in clinical and epidemiological samples, little is known about the prevalence, clinical presentation, course, risk factors and patterns of treatment-seeking of co-occurring PTSD-AD among the general pop...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2013.04.016
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Recovery support models (RSMs) integrate peer supports and continuing care to promote sustained recovery for adolescents with substance use disorder. RSMs aim to build recovery capital (RC), the personal, social, and environmental resources required to sustain recovery. The Alternative Peer Group (APG) is an...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2019.02.025
更新日期:2019-06-01 00:00:00
abstract::Although opioid withdrawal ratings are frequently used as primary outcomes for therapeutic trials, there has been limited empirical examination of opioid withdrawal symptom onset or etiology as an outcome, and also little examination of differences in outcomes between patient-reported and observer-ratings of withdrawa...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2020.108212
更新日期:2020-10-01 00:00:00
abstract:RATIONALE:Acute doses of buprenorphine can precipitate withdrawal in opioid dependent persons. The likelihood of this withdrawal increases as a function of the level of physical dependence. OBJECTIVES:To test the acute effects of sublingual buprenorphine/naloxone tablets in volunteers with a higher level of physical d...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2007.04.006
更新日期:2007-10-08 00:00:00
abstract:BACKGROUND:Some US payers are starting to vary payment to providers depending on patient outcomes, but this approach is rarely used in substance use disorder (SUD) treatment. PURPOSE:We examine the feasibility of applying a pay-for-outcomes approach to SUD treatment. METHODS:We reviewed several relevant literatures: ...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,评审
doi:10.1016/j.drugalcdep.2019.107735
更新日期:2020-01-01 00:00:00
abstract::Serum calcitonin (CT) concentrations were determined in 96 heroin addicts. CT levels were assayed by radioimmunological method employing two antisera, one vs. the 17-32 fraction (IMN) of the human CT, the other vs. the 11-32 fraction (B7). In heroin addicts the CT mean values were significantly higher (P less than 0.0...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(88)90052-x
更新日期:1988-10-01 00:00:00
abstract::Despite extensive evidence that selective dopamine antagonists attenuate the reinforcing effects of stimulants in laboratory animals, there is little evidence that dopamine antagonists block the positive subjective effects of stimulants in humans. However, recent evidence suggests that the subjective effects of stimul...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0376-8716(02)00104-7
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:This study assessed whether oral administration of delta-9-tetrahydrocannbinol (THC) effectively suppressed cannabis withdrawal in an outpatient environment. The primary aims were to establish the pharmacological specificity of the withdrawal syndrome and to obtain information relevant to determining the pot...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2006.04.014
更新日期:2007-01-05 00:00:00
abstract:BACKGROUND/OBJECTIVE:This study used a case-control female sample to test psychiatric mediators and genetic moderators of the effect of sexual abuse on later alcohol dependence. The study also tested differences between alcohol dependent women with or without a history of sexual abuse on variables that might affect tre...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2010.10.024
更新日期:2011-06-01 00:00:00
abstract::This paper will examine how cerebral perfusion deficits in cocaine abusers may be a target for pharmacotherapy. The review covers five areas: (1) cerebral ischemia and neuropsychological impairment in cocaine abusers, (2) neuroimaging evidence for cerebral perfusion defects in cocaine abusers, (3) mechanisms for cocai...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,评审
doi:10.1016/s0376-8716(97)00158-0
更新日期:1998-01-01 00:00:00
abstract:AIMS:This study aimed at examining a possible association between cannabis use in adolescence and future disability pension (DP). DP can be granted to any person in Sweden aged 16-65 years if working capacity is judged to be permanently reduced due to long-standing illness or injury. METHODS:Data were obtained from a ...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2014.07.038
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The primary objective of this pilot study was to describe the impact of e-cigarette liquid flavors on experienced e-cigarette users' vaping behavior. METHODS:11 males and 3 females participated in a 3-day inpatient crossover study using e-cigarettes with strawberry, tobacco, and their usual brand e-liquid. N...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2018.04.032
更新日期:2018-08-01 00:00:00
abstract::A common observation in the research literature is that children of drug-dependent parents are at significantly heightened risk of adolescent drug use, abuse, and dependence. Recent research indicates that several psychological and interpersonal factors may affect the association between parents' psychoactive substanc...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/s0376-8716(02)00005-4
更新日期:2002-05-01 00:00:00
abstract::The weight, histology and RNA, DNA, protein and lipid content of the liver and arterial and portal plasma amino acid concentrations were determined in male Sprague-Dawley rats fed a liquid diet which met AIN-76A standards with 36% of the calories supplied by ethanol. The dietary components of the dry mixture in percen...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(88)90036-1
更新日期:1988-10-01 00:00:00
abstract:INTRODUCTION:The objective of this study was to understand how adolescent substance use patterns may lead to negative mental health outcomes. METHODS:Data from adolescents (12-17 years old at baseline, Wave 1) who participated in the first 3 waves of the Population Assessment of Health and Tobacco (PATH) study were us...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2020.108385
更新日期:2021-01-01 00:00:00
abstract::This study examined the extent to which social relationships were associated with continued injection drug use and needle sharing among 252 methadone maintenance patients. Logistic regression analyses indicated that drug use was highest among persons who had a substance using live-in partner and among those with more ...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/s0376-8716(00)00230-1
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:This study investigated the applicability of the Chinese versions of Drug Abuse Screening Test (DAST) to detect illicit substance use in college students. METHODS:The data arising from a campus prevention program, Screening for Illicit Substance Use in College (SISUC), were utilized to explore the psychomet...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2020.108184
更新日期:2020-10-01 00:00:00
abstract::Familiarity with alcoholic beverages was assessed by means of a modified version of Jahoda and Cramond's 'Recognition of Smells' task (Jahoda, G. and Cramond, J. (1972) Children and Alcohol, HMSO, London). Two hundred and thirty-eight Scottish and English children aged 5.5-6.5, 7.5-8.5 and 9.5-10.5 years participated....
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(93)90043-p
更新日期:1993-12-01 00:00:00
abstract::Neonates born to opioid-maintained mothers are at risk of developing neonatal abstinence syndrome (NAS), which often requires pharmacological treatment. This study examined the effect of opioid maintenance treatment on the incidence and timing of NAS, and compared two different NAS treatments (phenobarbital versus mor...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章
doi:10.1016/j.drugalcdep.2006.08.024
更新日期:2007-03-16 00:00:00
abstract:BACKGROUND:The present study examined (1) the association between changes in perceived parental control and support from age 13 to 15 and early onset of cannabis use (before age 16), and (2) whether personality modifies the association between a decline in perceived parental control and support and early onset of canna...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2014.11.004
更新日期:2015-01-01 00:00:00
abstract::The goal of this study was to determine the contribution of substance abuse to the expression of suicidal ideation in a sample of patients referred for evaluation of chemical dependency in a large urban Psychiatric Emergency Service (PES). Records from 777 consecutive patients referred to the chemical dependency servi...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/s0376-8716(02)00337-x
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Stressful life events (SLEs) play a key role in suicidal behavior among adults with alcohol use disorders (AUD), yet there are meager data on the severity of SLEs preceding suicidal behavior or the timing of such events. METHOD:Patients in residential substance use treatment who made a recent suicide attemp...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2011.07.013
更新日期:2012-01-01 00:00:00
abstract::Adult female Sprague-Dawley rats were prepared with chronic intravenous cannulas and cortical and muscle electrodes for recording electroencephalograms and electromyograms, respectively. They were made physically dependent on morphine by automatic intravenous injections and then trained to lever press in order to self...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(77)90014-x
更新日期:1977-03-01 00:00:00
abstract:BACKGROUND:Disruptions in motor control are often overlooked features of chronic cocaine users. During a simple sensorimotor integration task, for example, cocaine users activate a larger area of cortex than controls but have lower functional connectivity between the cortex and dorsal striatum, which is further correla...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2015.07.1196
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:There is some debate whether smoking during pregnancy causes or is only a risk factor for negative academic outcomes and increased risk of psychopathology in offspring. This study evaluated whether maternal smoking cessation would reduce the risk of adverse outcomes in school-aged children. METHODS:Women co...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2011.08.004
更新日期:2012-02-01 00:00:00
abstract::The effects of morphine on extracellular dopamine levels in brain have never been studied over a wide range of doses within a single study. This has made it difficult to make definitive interpretations of drug interactions with morphine. An inhibition of morphine-induced increases in dopamine could be interpreted as e...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/s0376-8716(01)00150-8
更新日期:2001-12-01 00:00:00
abstract:UNLABELLED:Boys with serious conduct and substance problems (Antisocial Substance Dependence (ASD)) repeatedly make impulsive and risky decisions in spite of possible negative consequences. Because prefrontal cortex (PFC) is involved in planning behavior in accord with prior rewards and punishments, structural abnormal...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2011.04.006
更新日期:2011-11-01 00:00:00
abstract::Data from research on traffic accident populations clearly indicate that a large proportion of accidents involve drivers under the age of twenty-five. Even after differential exposure to traffic accidents has been controlled for, young drivers remain over-represented in both alcohol-related and non-alcohol-related tra...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(82)90084-9
更新日期:1982-09-01 00:00:00
abstract::Olfactory evoked potentials (OEP) were elicited by odorous and nonodorous stimuli in 50 adult subjects: 26 subjects with histories of either cocaine (n = 19) or alcohol (n = 7) dependence, 10 with histories of nicotine but no other drug dependence, 2 with clinical anosmia of peripheral origin, and 12 subjects without ...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章
doi:10.1016/0376-8716(96)01258-6
更新日期:1996-09-01 00:00:00