F-18 FDG PET/CT findings of a case of sacral nerve root neurolymphomatosis that occurred during chemotherapy.

Abstract:

:Neurolymphomatosis (NL) is a rare, unique subtype of lymphomatous infiltration of peripheral nerves. Clinical/radiologic diagnosis of NL is challenging. We report F-18 FDG PET/CT findings of a case of breast diffuse large B-cell lymphoma, in which NL developed regardless of regression of systemic lesions during induction chemotherapy. FDG PET/CT showed characteristic findings of well-demarcated, linear abnormal FDG uptake along a sacral vertebral foramen, leading to diagnosis of NL, with the finding of thickened nerve roots on magnetic resonance imaging. Altered chemotherapeutic regimen resulted in disappearance of these abnormal FDG uptake, with recovery of neurologic symptoms. Peripheral nerve NL may occur during chemotherapy, and FDG PET/CT can be a useful imaging modality in diagnosis and monitoring of therapeutic response of this disease.

journal_name

Clin Nucl Med

authors

Suga K,Yasuhiko K,Matsunaga N,Yujiri T,Nakazora T,Ariyoshi K

doi

10.1097/RLU.0b013e3181f4a03f

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

73-6

issue

1

eissn

0363-9762

issn

1536-0229

pii

00003072-201101000-00023

journal_volume

36

pub_type

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