Abstract：
OBJECTIVE:We retrospectively evaluated the survival outcome of patients with brain metastasis from hepatocellular carcinoma (HCC). METHODS:Between 1991 and 2007, a total of 20 patients were diagnosed as having brain metastasis from HCC. The mean age of the patients was 55 +/- 13 years, and 17 (85.0%) were men. Seventeen (85.0%) patients had already extracranial metastases. The median time from diagnosis of HCC to brain metastasis was 18.5 months. Fourteen (70.0%) patients had stroke-like presentation due to intracerebral hemorrhage (ICH). Ten (50.0%) patients had single or solitary brain metastasis. Among a total of 34 brain lesions, 31 (91.2%) lesions had the hemorrhagic components. RESULTS:The median survival time was 8 weeks (95% CI, 5.08-10.92), and the actuarial survival rates were 85.0%, 45.0%, 22.5%, and 8.4% at 4, 12, 24, and 54 weeks. Age < 60 years, treatment of the primary and/or extracranial lesions, and recurrent ICH were the possible prognostic factors (p = 0.044, p < 0.001, and p = 0.111, respectively). The median progression-free survival (PFS) time was 3 months (95% CI, 0.95-5.05). CONCLUSION:The overall survival of the patients with brain metastasis from HCC was very poor with median survival time being only 8 weeks. However, the younger patients less than 60 years and/or no extracranial metastases seem to be a positive prognostic factor.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Han JH,Kim DG,Park JC,Chung HT,Paek SH,Chung YSdoi
10.3340/jkns.2010.47.5.325subject
Has Abstractpub_date
2010-05-01 00:00:00pages
325-31issue
5eissn
2005-3711issn
1598-7876journal_volume
47pub_type
杂志文章abstract：:Chronic subdural hematoma (SDH) is a well-known disease entity and is traditionally managed with surgery. However, when associated with spontaneous intracranial hypotension (SIH), the treatment strategy ought to be modified, as classical treatment could lead to unwanted consequences. A 59-year-old man presented with a...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2016.59.1.69
更新日期：2016-01-01 00:00:00
abstract：:Pleomorphic xanthoastrocytoma (PXA) has been considered as a low grade tumor of adolescents and young adults. Although this tumor often shows cystic component, the hemorrhage within the cyst is extremely rare. The authors report a rare case of cystic PXA with a hemorrhage within the cyst and the mural nodule in the le...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2007.42.5.410
更新日期：2007-11-01 00:00:00
abstract：:Superior petrosal sinus (SPS) dural arteriovenous fistula (DAVF) is one of tentorial DAVFs with significant morbidity, which usually drains into the petrosal vein and its tributaries. Unless there is a connection with venous sinus, surgical obliteration is required. We present two cases of SPS DAVF which were successf...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2011.49.4.222
更新日期：2011-04-01 00:00:00
abstract：Objective:Electrooculography (EOG) records eyeball movements as changes in the potential difference between the negatively charged retina and the positively charged cornea. We aimed to investigate whether reliable EOG waveforms can be evoked by electrical stimulation of the oculomotor and abducens nerves during skull b...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2020.0179
更新日期：2020-12-23 00:00:00
abstract：OBJECTIVE:This study characterized the neurons in the lumbosacral cord that express phospho ERK (pERK) after distension or irritation of the bladder, and their relation to the vanilloid receptor 1 (VR1) positive primary afferents. METHODS:Mechanical distension and chemical irritation of the bladder were induced by int...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2007.42.6.462
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:Cardiac dysfunction after aneurysmal subarachnoid hemorrhage (SAH) is associated with elevation of serum cardiac troponin I (cTnI) levels. Elevation of cTnI predicts cardiopulmonary and neurological complications, and poor outcome. METHODS:We retrospectively reviewed the medical and radiologic records of 114...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2009.46.2.99
更新日期：2009-08-01 00:00:00
abstract：:The Chiari 1.5 malformation is defined as a tonsillar herniation within a Chiari I malformation with additional caudal descent of the brainstem through the foramen magnum. We describe a patient with Chiari I malformation who evolved to Chiari 1.5 malformation during longitudinal follow-up. A 15-year-old girl presented...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2010.48.4.375
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:The purpose of the present study is to assess the long-term results of microsurgical dorsal root entry zonotomy (MDT) for the treatment of medically intractable upper-extremity spasticity. METHODS:The records of nine adult patients who underwent MDT by one operating neurosurgeon from March 1999 to June 2004 ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2008.43.4.182
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:This 2009-2011 nation-wide study of adult Koreans was aimed to provide characteristics, medical utilization states, and survival rates for newly diagnosed patients with primary nonmalignant and malignant spine tumors. METHODS:Data for patients with primary spine tumors were selected from the Korean Health In...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.0505.011
更新日期：2017-03-01 00:00:00
abstract：:In conventional percutaneous disc surgery, introducing instruments into disc space starts by inserting a guide needle into the triangular working zone. However, landing the guide needle tip on the annular window is a challenging step in endoscopic discectomy. Surgeons tend to repeat the needling procedure to reach an ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.51.3.182
更新日期：2012-03-01 00:00:00
abstract：:The crossing Y-stent method is one of the indispensable techniques to achieve sufficient neck coverage during coil embolization of bifurcation aneurysms with a wide neck and/or branch incorporation. However, the inevitable hourglass-like expansion of the second stent at the crossing point can result in insufficient ve...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2019.0253
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:We investigated the clinical and radiological advantages of unilateral laminectomy in posterior lumbar interbody fusion (PLIF) procedure comparing with bilateral laminectomy, under the same procedural condition including bilateral instrumentation and insertion of two cages, in patients with degenerative lumba...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2011.50.4.363
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To analyze trends in the incidence and treatment of diseases associated with ischemic stroke, namely, cerebral infarction (CI), cerebral arterial stenosis (CASTN), and moyamoya disease (MMD), based on Korean National Health Insurance Service (NHIS) data from 2008 to 2016. METHODS:Data was extracted from the ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2018.0182
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to compare the surgical outcome of the initial and recent surgical cases, during our 15-years experience, in terms of the surgical strategies and the prognostic factors for surgically remediable epilepsy. METHODS:We retrospectively reviewed and compared the surgical outcomes between ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.48.3.230
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:Residual aneurysm from incomplete clipping or slowly recurrent aneurysm is associated with high risk of subarachnoid hemorrhage. We describe complete treatment of the lesions by surgical clipping or endovascular treatment. METHODS:We analyzed 11 patients of residual or recurrent aneurysms who had undergone s...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.48.4.330
更新日期：2010-10-01 00:00:00
abstract：:It is not uncommon for hemangiomas to occur in the calvarium, accounting for about 10% of the benign skull tumors. A 46-year-old man was presented with a palpable scalp mass on the left parietal region. Past medical history indicated that he had undergone cranioplasty 25 years prior due to a depressed skull fracture s...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2009.46.5.484
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:Because the anatomical structure of the brachial plexus is very complex, surgical treatment of tumors in this region is challenging. Therefore, a lot of clinical and surgical experience is required for successful treatment; however, many neurosurgeons have difficulty accumulating this experience owing to the ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2018.0045
更新日期：2018-09-01 00:00:00
abstract：:Diffuse intrinsic pontine glioma (DIPG) is a deadly paediatric brain cancer. Transient response to radiation, ineffective chemotherapeutic agents and aggressive biology result in rapid progression of symptoms and a dismal prognosis. Increased availability of tumour tissue has enabled the identification of histone gene...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章,评审
doi：10.3340/jkns.2018.0008
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:We report experiences and clinical outcomes of 61 cases with spinal canal meningiomas from January 1970 through January 2005. METHODS:Thirty-eight patients were enrolled with follow-up duration of more than one year after surgery. There were 7 male and 31 female patients. The mean age was 52 years (range, 19...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2007.42.4.300
更新日期：2007-10-01 00:00:00
abstract：:Malignant peripheral nerve sheath tumors (MPNSTs) are very rare tumors. We experienced a case of MPNST in the cervical paraspinal space which was not associated with neurofibromatosis. The tumor located in left C6-7 foramen and compressed C7 root. The tumor was removed through the occipital triangle. We report a case ...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2008.44.2.91
更新日期：2008-08-01 00:00:00
abstract：:Posttraumatic delayed vertebral collapse, known as Kummell's disease, is increasing in number of patients. This disease is already progressive kyphosis due to vertebral collapse at the time of diagnosis and it causes intractable pain or neurologic deficit due to intravertebral instability. Treatment is very difficult ...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章,评审
doi：10.3340/jkns.2017.0505.010
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:The aims of this study were to investigate the quantitative relationship between pituitary macroadenoma size and degree of visual impairment, and assess visual improvement after surgical resection of the tumor. METHODS:The medical records of patients with pituitary adenoma, who had undergone trans-sphenoidal...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2015.57.1.23
更新日期：2015-01-01 00:00:00
abstract：:Intracranial granulocytic sarcomas are rare tumors, which are composed of immature granulocytic cells. Although it has been well known that these tumors are associated with acute myeloblastic leukemia (AML), they have been almost always related to bone marrow relapse. However, isolated recurrence of granulocytic sarco...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2010.47.5.385
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to assess the safety and efficacy of the dynamic stabilization system in the treatment of degenerative spinal diseases. METHODS:The study population included 20 consecutive patients (13 females, 7 males) with a mean age of 61+/-6.98 years (range 46-70) who underwent decompres...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2008.43.5.221
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:Recently, regenerative therapies have been used in clinical trials (heart, cartilage, skeletal). We don't make use of these treatments to spinal cord injury (SCI) patients yet, but regenerative therapies are rising interest in recent study about SCI. Neural precursor/stem cell (NPSC) proliferation is a signif...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.59.5.437
更新日期：2016-09-01 00:00:00
abstract：:To review recent advances in endoscopic techniques for treating intraventricular lesions via transcortical passage. Articles in PubMed published since 2000 were searched using the keywords 'endoscopy,' 'endoscopic,' and 'neuroendoscopic.' Of these articles, those describing intraventricular lesions were reviewed. Supr...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章,评审
doi：10.3340/jkns.2017.0101.008
更新日期：2017-05-01 00:00:00
abstract：:Plasma cell granuloma is a tumor-like disease characterized by non-neoplastic polyclonal proliferation of plasma cells and other mononuclear cells. This disease occurs most frequently in the lung and upper respiratory tract, while the involvement of the central nervous system is very rare. A 44-year-old female patient...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2009.46.2.161
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:The indications and optimal surgical treatments for intracranial cysts are controversial. In the present study, we describe long-term clinical and neuroimaging results of surgically treated intracranial cysts in children. The goal of this study is to contribute to the discussion of the debate. METHODS:This s...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.52.4.325
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:Outcome of gamma knife radiosurgery (GKS) in the consecutive 100 cases with cerebral arteriovenous malformations (AVMs) was analyzed. METHODS:Data from initial 100 patients treated with GKS in the authors' institute were reviewed retrospectively. Spetzler-Martin grade at diagnosis were I in 18 patients, II i...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2008.43.6.265
更新日期：2008-06-01 00:00:00
abstract：:We present a case report of a 45-year-old woman with spontaneous pneumocephalus accompanied by pneumorrhachis of the thoracic spine, which is a very rare condition generally associated with trauma and thoracic or spinal surgery. The patient had undergone an operation about 10 years earlier to treat a giant cell tumor ...
journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2011.50.1.64
更新日期：2011-07-01 00:00:00
