A target-specific electrode and lead design for internal globus pallidus deep brain stimulation.

Abstract:

:In nearly all deep brain stimulation (DBS) applications, the same quadripolar electrode design is used for different anatomical targets even if shape and volume differences exist between nuclei. Taking into account the electrode location within the internal globus pallidus (GPi) and the size of the GPi, 2 electrodes were designed in order to improve the therapeutic benefit, to minimize side effects from DBS and to obtain a more homogeneous electric field distribution. The electrodes were evaluated numerically by using a stereotactic model measuring the correlation between the electric field and the GPi. The model was applied to 26 dystonodyskinetic patients who underwent surgery for a bilateral lead implantation into the posteroventral part of the GPi. The designed electrodes produced a more homogeneous distribution of the electric field than the quadripolar electrode.

authors

Vasques X,Cif L,Mennessier G,Coubes P

doi

10.1159/000303524

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

129-37

issue

3

eissn

1011-6125

issn

1423-0372

pii

000303524

journal_volume

88

pub_type

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