Abstract:
:In laboratory studies of individual differences in stress reactivity, cortisol responses are typically measured by comparing a prestress baseline with values obtained at the end of the stressor. In the present study, we measured cortisol in this manner on a stress day, but we also took samples on a second day when the volunteers rested in the lab at the same time of day and for the same duration. We compared stress responses as the difference from pre- to poststress and also poststress vs. rest day control. The latter method allowed a greater appreciation of how stress perturbed the underlying diurnal baseline. Although the effect of stress was statistically significant when measured as the change from pre- to poststress, the magnitude of the effect was 54% larger when measured against the time-of-day control from the rest day. In particular the diurnal control method provided a wider range of stress values that potentially provide a greater range of response values in carrying out analyses of individual differences.
journal_name
Psychoneuroendocrinologyjournal_title
Psychoneuroendocrinologyauthors
Lovallo WR,Farag NH,Vincent ASdoi
10.1016/j.psyneuen.2010.02.015subject
Has Abstractpub_date
2010-09-01 00:00:00pages
1253-8issue
8eissn
0306-4530issn
1873-3360pii
S0306-4530(10)00060-0journal_volume
35pub_type
杂志文章abstract::Oxytocin receptors in several regions of the limbic system are regulated by gonadal steroids and play an important role in the mediation of maternal, sexual and affiliative behaviors. We have previously reported oxytocin receptor regulation by glucocorticoids in hippocampus and subiculum-neuroanatomical regions implic...
journal_title:Psychoneuroendocrinology
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journal_title:Psychoneuroendocrinology
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