Abstract:
INTRODUCTION:Ablation electrode-tissue contact has been shown to be an important determinant of lesion size and safety during nonirrigated ablation but little data are available during irrigated ablation. We aimed to determine the importance of contact force during irrigated-tip ablation. METHODS AND RESULTS:Freshly excised hearts from 11 male pigs were perfused and superfused using fresh, heparinized, oxygenated swine blood in an ex vivo model. One-minute ablations were placed using one of 3 different power control strategies (impedance control-15 Omega target impedance drop, and 20 W or 30 W fixed power) and 3 different contact forces (2 g, 20 g, and 60 g) to give a grid of 9 ablation groups. The force sensing catheter (Tacticath, Endosense SA) was irrigated at 17 mL/min for all of the ablations. Of a total 101 ablations, no thrombus formation was noted but popping was seen in 17 lesions. The lesion depth and incidence of pops was 5.0 +/- 1.3 mm /0%, 5.0 +/- 1.6 mm /10% and 6.7 +/- 2.5 mm /45% for the 15 Omega, 20 W, and 30 W groups (P < 0.01), respectively, and 4.4 +/- 1.8 mm /3%, 5.8 +/- 1.6 mm /17% and 6.6 +/- 2.0 mm /37% for the 2 g, 20 g, and 60 g groups, respectively (P < 0.01). The impedance drop in the first 5 seconds was significantly correlated to catheter contact force: 9.7 +/- 9.9 Omega, 22.3 +/- 11.0 Omega, and 41.7 +/- 22.1 Omega, respectively, for the 2 g, 20 g, and 60 g groups (Pearson's r = 0.65, P < 0.01). CONCLUSION:Catheter contact force has an important impact on both ablation lesion size and the incidence of pops.
journal_name
J Cardiovasc Electrophysioljournal_title
Journal of cardiovascular electrophysiologyauthors
Thiagalingam A,D'Avila A,Foley L,Guerrero JL,Lambert H,Leo G,Ruskin JN,Reddy VYdoi
10.1111/j.1540-8167.2009.01693.xsubject
Has Abstractpub_date
2010-07-01 00:00:00pages
806-11issue
7eissn
1045-3873issn
1540-8167pii
JCE1693journal_volume
21pub_type
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journal_title:Journal of cardiovascular electrophysiology
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
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更新日期:2013-05-01 00:00:00
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
doi:10.1111/j.1540-8167.2000.tb00014.x
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pub_type: 杂志文章
doi:10.1046/j.1540-8167.2001.00026.x
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pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2001-10-01 00:00:00
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiovascular electrophysiology
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doi:10.1046/j.1540-8167.2004.03488.x
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abstract::About one fifth of all deaths occur suddenly and unexpectedly, often as the first manifestation of heart disease. Several tests have been developed during the past 2 decades for risk stratification of such an event, but only a minority of victims can be identified as being at high risk before sudden death occurs. Impr...
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abstract:INTRODUCTION:Electrical stimuli produce a spatial distribution of voltage across the heart. We hypothesized that the potential difference between tissue near a stimulating electrode and a remote site could cause sufficient current to flow through a highly conductive wire connecting the two sites to directly stimulate t...
journal_title:Journal of cardiovascular electrophysiology
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pub_type: 杂志文章
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 临床试验,杂志文章
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更新日期:2007-12-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of cardiovascular electrophysiology
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章,评审
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更新日期:2013-09-01 00:00:00
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pub_type: 临床试验,杂志文章
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