Abstract:
INTRODUCTION:In patients with permanent pacemakers, mode switching events often are interpreted as surrogate markers for atrial tachyarrhythmias. The aim of this study was to determine the accuracy of automatic mode switching algorithms in patients with permanent pacemakers for the diagnosis of atrial tachyarrhythmias. METHODS AND RESULTS:Forty patients with tachycardia-bradycardia syndrome and Medtronic Thera or Kappa 700 permanent pacemakers underwent Holter monitoring. Date, time of onset, and duration of each mode switch episode as recorded by the pacemaker and each atrial tachyarrhythmia episode as recorded by the Holter monitor were compared. Sixteen patients had a total of 54 atrial tachyarrhythmias documented on Holter monitoring (47 atrial fibrillation, 7 atrial flutter). Comparison of Holter data with pacemaker interrogation demonstrated that 53 (98.1%) of 54 atrial tachyarrhythmia episodes resulted in mode switching with one 13-second episode of mode switching during sinus rhythm. The sensitivity and specificity of mode switching for the duration of atrial tachyarrhythmias were 98.1% and 100%, respectively. The algorithms detected 98.9% of the total duration of atrial fibrillation and 96.4% of the total duration of atrial flutter. CONCLUSION:In patients with tachycardia-bradycardia syndrome and permanent pacemakers having these mode switching algorithms, mode switching events are reliable surrogate markers for atrial tachyarrhythmias. Therefore, mode switching may serve as a valuable tool for clinical decision making and further research into the natural history and burden of atrial tachyarrhythmias.
journal_name
J Cardiovasc Electrophysioljournal_title
Journal of cardiovascular electrophysiologyauthors
Passman RS,Weinberg KM,Freher M,Denes P,Schaechter A,Goldberger JJ,Kadish AHdoi
10.1046/j.1540-8167.2004.03537.xkeywords:
subject
Has Abstractpub_date
2004-07-01 00:00:00pages
773-7issue
7eissn
1045-3873issn
1540-8167pii
JCE03537journal_volume
15pub_type
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journal_title:Journal of cardiovascular electrophysiology
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doi:10.1046/j.1540-8167.2002.00525.x
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doi:10.1111/j.1540-8167.1998.tb00959.x
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION:It has been speculated that pacemaker current (I(f)) in human atria could play a role in causing ectopic atrial automaticity. Ivabradine is a novel selective and specific I(f) inhibitor in the sinus node that reduces heart rate without any negative inotropic effect. The aim of the study was to explore poss...
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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doi:10.1111/j.1540-8167.2006.00546.x
更新日期:2006-09-01 00:00:00
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
doi:10.1111/j.1540-8167.1999.tb00715.x
更新日期:1999-04-01 00:00:00
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
doi:10.1046/j.1540-8167.2001.00662.x
更新日期:2001-06-01 00:00:00
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journal_title:Journal of cardiovascular electrophysiology
pub_type:
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更新日期:2020-11-01 00:00:00
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doi:10.1046/j.1540-8167.2003.02100.x
更新日期:2003-05-01 00:00:00
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2003-08-01 00:00:00
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
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pub_type: 杂志文章,评审
doi:10.1111/j.1540-8167.1994.tb01190.x
更新日期:1994-08-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2016-12-01 00:00:00
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journal_title:Journal of cardiovascular electrophysiology
pub_type: 杂志文章
doi:10.1111/j.1540-8167.2000.tb00014.x
更新日期:2000-05-01 00:00:00
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更新日期:2017-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Focal atrial tachycardias (FAT) originate from areas with poor cell-to-cell coupling. Due to cellular uncoupling extracellular potentials become fractionated. The degree of fragmentation may be used to identify the site of origin of FAT prior to catheter ablation. We studied electrical fragmentation in relat...
journal_title:Journal of cardiovascular electrophysiology
pub_type: 临床试验,杂志文章
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更新日期:2006-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-04-01 00:00:00