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Issues in subgroup analyses and meta-analyses of clinical trials.

Abstract：

:This commentary discusses two techniques commonly used to analyze clinical trials: subgroup analysis and meta-analysis. Subgroup analysis is used to evaluate the consistency of a treatment across multiple groups, usually within a clinical trial. Subgroup analysis often is used to generate or test an hypothesis about risk factors or treatment responses. Meta-analysis (overview) is used primarily to summarize data from several randomized clinical trials and to evaluate consistency among trials. Meta-analysis is a formal way of summarizing the totality of information coming from well-conducted randomized clinical trials. The use and limitations of these two techniques are discussed.

journal_name

J Cardiovasc Electrophysiol

journal_title

Journal of cardiovascular electrophysiology

authors

Bigger JT

doi

10.1046/j.1540-8167.14.s9.1.x

keywords:

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

S6-8

issue

9 Suppl

eissn

1045-3873

issn

1540-8167

journal_volume

14

pub_type

杂志文章

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