A model of anuran retina relating interneurons to ganglion cell responses.

Abstract:

:A model is presented which accounts for many characteristic response properties used to classify anuran ganglion cell types while being consistent with data concerning interneurons. In the model color is ignored and input stimuli are assumed to be only black and white at high contrast. We show that accurate ganglion cell responses are obtained even with simplified receptors and horizontal cells: Receptors are modeled as responding with a step change, while horizontal cells respond only to global changes in intensity brought about by full field illumination changes. A hyperpolarizing and depolarizing bipolar cell are generated by subtracting local receptor and horizontal potentials. Two transient amacrine cells (On and Off) are generated using a high-pass filter like mechanism with a thresholded output which responds to positive going changes in the corresponding bipolar cell potentials. The model shows how a selective combination of bipolar and amacrine channels can account for many of the response properties used to classify the anuran ganglion cell types (class-0 through 4) and makes several experimental predictions.

journal_name

Biol Cybern

journal_title

Biological cybernetics

authors

Teeters JL,Arbib MA

doi

10.1007/BF00201980

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

197-207

issue

3

eissn

0340-1200

issn

1432-0770

journal_volume

64

pub_type

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