Abstract:
:There is a growing understanding that chronic respiratory diseases in adults have their origins in early life. Adverse environmental exposures occurring in vulnerable periods during lung growth and development in the fetal period and in early childhood that alter lung structure and limit the growth in lung function may have lifelong consequences. Evidence is increasing that exposure to the ambient environment, including air pollutants, persistent toxic substances, water pollutants and respiratory viral infections, can inhibit lung function growth and predispose to chronic non-malignant lung diseases. These exposures generally interact with a genetic predisposition, and gene-environment interactions and epigenetic phenomena are attracting considerable study. An understanding of how ambient exposures impact on normal lung growth and development will aid in understanding of how chronic respiratory diseases of adults develop and may lead to new preventative strategies.
journal_name
Chron Respir Disjournal_title
Chronic respiratory diseaseauthors
Soto-Martinez M,Sly PDdoi
10.1177/1479972309345929subject
Has Abstractpub_date
2010-08-01 00:00:00pages
173-86issue
3eissn
1479-9723issn
1479-9731pii
1479972309345929journal_volume
7pub_type
杂志文章,评审abstract::Pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) improves exercise tolerance and health status, however, these effects have been shown to decline after termination of the rehabilitation program. This study has examined the long-term effect of a 7-week supervised rehabilitation program combined ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972307087366
更新日期:2008-01-01 00:00:00
abstract::Some patients suffer from clinical symptoms of chronic obstructive pulmonary disease (COPD) but their pulmonary function tests are in the normal range (at risk group). The objective of this study was to discover a practical test to distinguish these patients from non-COPD subjects. A total of 77 subjects including 40 ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972313507461
更新日期:2013-01-01 00:00:00
abstract::Patients with bronchiectasis (BE) present exacerbations that increase with severity of the disease. We aimed to determine the annual cost of BE treatment according to its severity, determined by FACED score, as well as the parameters associated with higher costs. Multicentre historical cohorts study with patients from...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972316643698
更新日期:2016-11-01 00:00:00
abstract::Shifts in natural or spontaneous language have been reported with psychological and physical changes, as well as shifts in predetermined words selected to describe dyspnea. Less evidence exists for natural language shifts and breathing intensity, particularly for everyday life and for negative emotion. Therefore, this...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972308096710
更新日期:2008-01-01 00:00:00
abstract::Patients with chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) commonly suffer from exertional symptoms of breathlessness and fatigue. The similar systemic manifestations of the conditions, including skeletal muscle dysfunction, are a major contributing factor to the limitation in exercise ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972311423111
更新日期:2011-01-01 00:00:00
abstract::The spread of the SARS-CoV-2 infection among population has imposed a re-organization of healthcare services, aiming at stratifying patients and dedicating specific areas where patients with suspected COVID-related respiratory disease could receive the necessary health care assistance while waiting for the confirmatio...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973120961843
更新日期:2020-01-01 00:00:00
abstract::Dyspnea-related anxiety may lead to reduced quality of life and functional disability through fearful avoidance of dyspnea-evoking activity. We describe the validation of a generic - diagnosis-independent - instrument assessing dyspnea-related anxiety. A total of 187 patients with respiratory diseases completed the Br...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972310383592
更新日期:2011-01-01 00:00:00
abstract::The aim of this study was to evaluate the clinical effects of cognitive impairment in patients with chronic obstructive pulmonary disease (COPD). A total of 91 patients with stable moderate to very severe COPD were included in this study. Cognitive functions of the patients were evaluated using the mini-mental state e...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972317743757
更新日期:2018-08-01 00:00:00
abstract::Recent advances in information communication technology allow contact with patients at home through e-Health services (telemedicine, in particular). We provide insights on the state of the art of e-Health and telemedicine for possible wider future clinical use. Telemedicine opportunities are summarized as i) home tele...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972309102805
更新日期:2009-01-01 00:00:00
abstract::The aim of this study is to conduct a systematic review of published studies that evaluate the impact of pulmonary rehabilitation (PR) on survival and fall (including balance) in patients with chronic obstructive pulmonary disease at stability. OVID, Medline, EMBASE, and Cochrane collaboration library were searched fo...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972316661925
更新日期:2017-02-01 00:00:00
abstract::There should be a clear pathway through pulmonary rehabilitation and follow-on services. The aim of this survey was to determine the characteristics of the different components of the patient pathway, that is, pulmonary rehabilitation programs, ongoing exercise facilities, and support networks in Northern Ireland. Que...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972308091825
更新日期:2008-01-01 00:00:00
abstract::Recent studies have suggested that an increased peripheral monocyte count predicts a poor outcome in fibrosing interstitial lung disease (ILD). However, the association between an increased monocyte count and acute exacerbations (AEs) of fibrosing ILD remains to be elucidated. Our retrospective cohort study aimed to a...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973120909840
更新日期:2020-01-01 00:00:00
abstract::Dixon and coworkers (Dixon AE, Sugar EA, Zinreich SJ, et al. Criteria to screen for chronic sinonasal disease. Chest 2009; 136: 1324-1332.) recently developed a five-item questionnaire for diagnosing chronic sinonasal disease in patients with asthma. Our study was designed to determine how frequently patients attendin...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972313485457
更新日期:2013-05-01 00:00:00
abstract::Sleep-disordered breathing (SDB) is a chronic condition characterized by repeated breathing pauses during sleep. The reported prevalence of SDB in the general population has increased over time. Furthermore, in the literature, a distinction is made between SDB, obstructive sleep apnea (OSA), and "OSA syndrome" (OSAS)....
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973120928103
更新日期:2020-01-01 00:00:00
abstract::Bronchiectasis is a chronic inflammatory lung disease, which has similarities to chronic obstructive pulmonary disease (COPD). Comorbidities of COPD include increased risk of cardiovascular (CV) disease, loss of bone mineral density (BMD) and loss of skeletal muscle mass and function, all linked to systemic inflammati...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972312459973
更新日期:2012-01-01 00:00:00
abstract::We aimed to investigate (1) the relationship between cognitive impairment (CI) and disease severity and (2) the potential differences in exercise performance, daily activities, health status, and psychological well-being between patients with and without CI. Clinically stable chronic obstructive pulmonary disease (COP...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972317709651
更新日期:2018-05-01 00:00:00
abstract::In a primary care setting, our aim was to investigate characteristics of patients classified as having chronic obstructive pulmonary disease (COPD) and currently being prescribed inhaled corticosteroids (ICSs). The electronic patient record system in each participating general practice was searched for patients coded ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973119867949
更新日期:2019-01-01 00:00:00
abstract::Self-management (SM) is defined as the provision of interventions to increase patients' skills and confidence, empowering the individual to take an active part in their disease management. There is uncertainty regarding the optimal format and the short- and long-term benefits of chronic obstructive pulmonary disease (...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972316687208
更新日期:2017-08-01 00:00:00
abstract::The aim of the study was to determine if there was a difference in 6-minute walk distance (6MWD) when two 6-minute walk tests (6MWTs) were performed at the initial assessment prior to attendance at the pulmonary hypertension (PH) clinic and at the 6-month follow-up. Two 6MWTs were performed at both visits on a 32-m co...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972317752762
更新日期:2018-11-01 00:00:00
abstract::Nutritional status has been associated with clinical outcome in chronic airflow limitation (CAL), but epidemiological studies are scarce. We aimed to assess the relationship between body mass index (BMI) and CAL, taking into account confounding factors. 18,606 participants (49% male, 21% smokers, mean age: 55.8 ± 11.2...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972315626012
更新日期:2016-05-01 00:00:00
abstract::The objective of this study was to evaluate task performance and handling errors with soft mist inhalers (SMIs) or pressurized metered-dose inhalers (pMDIs) among patients with chronic obstructive pulmonary disease (COPD) experienced with, but not recently trained in, using these devices. This exploratory, noninterven...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,多中心研究
doi:10.1177/1479972318787914
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Many deaths are now preceded by an end of life decision, particularly in the intensive care unit (ICU), but such practices vary considerably between countries, ICUs and individuals, depending on many factors including cultural and religious background, family and peer pressure and local practice. AIMS:In th...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1191/1479972304cd021rs
更新日期:2004-01-01 00:00:00
abstract::Acute effects of music and relaxation have not been evaluated in hospitalized subjects with chronic obstructive pulmonary disease (COPD). This study aims to evaluate the acute effects of music and progressive muscle relaxation (PMR) in hospitalized COPD subjects after a recent episode of exacerbation. A Randomized con...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1479972309346754
更新日期:2009-01-01 00:00:00
abstract::To inform recommendations for the exercise component of a healthy lifestyle intervention for adults with obesity and treated obstructive sleep apnoea (OSA), we investigated the total energy expenditure (EE) and cardiorespiratory response to weight-supported (cycling) and unsupported (walking) exercise. Individuals wit...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972316643699
更新日期:2017-11-01 00:00:00
abstract::The aim of this study was to give an in-depth consideration of the chronic obstructive pulmonary disease (COPD) patients' subjective view of the impact of pulmonary rehabilitation (PR) on their lives. A systematic review in PubMed, Embase, CINAHL and PsychInfo databases yielded 3306 articles, of which 387 were duplica...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972313493796
更新日期:2013-08-01 00:00:00
abstract::Pulmonary rehabilitation (PR) is recommended for people with interstitial lung disease (ILD); however, the educational content of PR was not designed for this group. This study explored the perspectives of patients and ILD clinicians regarding the educational content of PR for ILD. A qualitative study using individual...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972315571925
更新日期:2015-05-01 00:00:00
abstract:AIMS:Benefits of long acting beta 2 agonists are unclear for severe chronic obstructive pulmonary disease (COPD) patients with poor response to short acting bronchodilators. We aimed to evaluate 1) effects of eformoterol in such patients using a 'n-of-1' double crossover study design, and 2) aggregate data as a double-...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,随机对照试验
doi:10.1191/1479972304cd028oa
更新日期:2004-01-01 00:00:00
abstract::It has been well defined that obesity is strongly linked with several respiratory symptoms and diseases, but no convincing evidence has been provided for chronic obstructive pulmonary disease (COPD). In the current study, we aim to assess the possible prevalence of obesity in patients with COPD in a cross-sectional ca...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972313504940
更新日期:2013-01-01 00:00:00
abstract::The objective of this study is to review available functional status measures (FSMs) validated for use in the chronic obstructive pulmonary disease (COPD) population and categorizing the measures by their commonalities to formulate a framework that supports clinicians in the selection and application of FSMs. A litera...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479973118816464
更新日期:2019-01-01 00:00:00
abstract::Pulmonary rehabilitation (PR) is an effective treatment for people with chronic obstructive pulmonary disease (COPD). However, uptake and adherence to rehabilitation is poor and non-adherence is associated with poorer clinical outcomes. This study investigated the factors that might predict an individual completing hi...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972314527469
更新日期:2014-05-01 00:00:00