A pharmacoeconomic review of adalimumab in the treatment of rheumatoid arthritis.

abstract：OBJECTIVE:To assess the cost-effectiveness of single pill fixed dose triple combination therapy vs. free triple combination therapy for the prevention of cardiovascular events among patients with hypertension. METHODS:A Markov model with a five year cycle was constructed. Two decision models incorporating strict and m...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Wang X,Chen H,Ej E,Wu J,Serna O,Paranjpe R,Abughosh S

更新日期：2020-08-01 00:00:00

abstract：:The incidence of melanoma has been climbing steadily since the early 1970s. Although melanoma can be successfully cured by surgical excision in its early stages, it is the most common fatal form of skin cancer. The most critical factors in determining the prognosis for patients with melanoma are primary tumor thicknes...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Cormier JN,Xing Y,Ross MI,Cantor SB

更新日期：2004-12-01 00:00:00

abstract：:Most national guidelines for pharmacoeconomic research prescribe discounting, mostly of money and health against the same rate. There is much debate on whether this is adequate. Two theoretical arguments, the consistency argument of Weinstein and Stason, and the paralyzing paradox of Keeler and Cretin, are mostly resp...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Klock RM,Brouwer WB,Annemans LJ,Bos JM,Postma MJ

更新日期：2005-02-01 00:00:00

abstract：:The Dutch basic health insurance is based on the principles of regulated competition. This implies that insurers and providers compete on price and quality while the regulator sets certain rules to achieve public objectives such as solidarity. Two regulatory aspects of this scheme are that insurers are not allowed to ...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： van Kleef RC,van de Ven WP,van Vliet RC

更新日期：2013-12-01 00:00:00

abstract：:Interest is rising in measuring subjective health outcomes, such as treatment outcomes that are not directly quantifiable (functional disability, symptoms, complaints, side effects and health-related quality of life). Health economists in particular have applied probabilistic choice models in the area of health evalua...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Arons AM,Krabbe PF

更新日期：2013-02-01 00:00:00

abstract：:The Institute for Quality and Efficiency in Health Care in Germany makes recommendations for ceiling prices of drugs based on an evaluation of the relationship between costs and effects in each therapeutic area. The analysis requires, when applicable, calculation of savings from avoided clinical events and increased f...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Gandjour A,Gafni A

更新日期：2011-08-01 00:00:00

abstract：INTRODUCTION:For optimum results from pharmacological management of overactive bladder, adherence to prescribed medication is required. Overactive bladder treatment has been compromised by low adherence and persistence to medications, losing many people who might benefit from treatment and exposing them to unnecessary ...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Wagg A

更新日期：2016-08-01 00:00:00

abstract：:Chronic obstructive pulmonary disease is a major cause of morbidity and mortality throughout the world. Standard management includes avoidance of causative factors such as smoking, and pharmacological therapy with combinations of inhaled and/or oral bronchodilators and corticosteroids. Lung transplantation is an estab...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Reed A,Williams T,Snell G

更新日期：2003-12-01 00:00:00

abstract：:Alzheimer's disease is a neurodegenerative disorder characterized by cognitive and behavioral deficits. Donepezil and memantine are two medications used to treat the symptoms of cognitive decline in Alzheimer's disease. A modeled cost-effectiveness analysis found that treatment with donepezil to be less costly and mor...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Oremus M,Tarride JE

更新日期：2012-06-01 00:00:00

abstract：:A review was undertaken to identify relevant and appropriate heath-utility estimates for patients with atrial fibrillation who had stroke and to appraise them against the published requirements for several countries' Health Technology Assessment agencies: Australia (Pharmaceutical Benefits Advisory Committee), Canada ...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Lloyd A,Wild D,Gallop K,Cowell W

更新日期：2009-12-01 00:00:00

abstract：:This article systematically appraises the findings and conclusions derived from six recent studies of the economic impact and relative value of using percutaneous ventricular assist devices to render short-term hemodynamic support to high-risk patients with particular attention to the settings of cardiogenic shock and...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Maini B,Scotti DJ,Gregory D

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Rotavirus diarrhea is a major health problem among young children worldwide with potential negative impacts on health-related quality of life (HRQoL). This study assessed the impact of rotavirus diarrhea on HRQoL of children and their caregivers. METHODS:We performed a cross-sectional study among 460 hospit...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Rochanathimoke O,Riewpaiboon A,Postma MJ,Thinyounyong W,Thavorncharoensap M

更新日期：2018-04-01 00:00:00

abstract：:Adalimumab is a monoclonal antibody that inhibits TNF, an osteogenic cytokine involved in the pathogenesis of chronic, disabling inflammatory diseases. Adalimumab is indicated for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. It alleviates the symptoms of these diseases, preven...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Gladman DD,Brown RE

更新日期：2008-04-01 00:00:00

abstract：:Fondaparinux sodium is the first in a new class of anticoagulants that selectively inhibits Factor Xa. It produces a predictable pharmacologic response, obviating the need for coagulation monitoring. Additionally, this agent does not bind to platelet Factor 4, thereby reducing the risk of thrombocytopenia. Clinical tr...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Wade WE,Spruill WJ

更新日期：2007-06-01 00:00:00

abstract：:This review was designed to explore and review the range of patient-reported outcomes used to assess people with epilepsy. Literature searches were conducted through EMBASE.com and supplemented with hand searching of relevant articles. References obtained through hand searches were compared with EMBASE.com citations u...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Stafford M,Gavriel S,Lloyd A

更新日期：2007-08-01 00:00:00

abstract：:A systematic review was conducted of the full economic evaluations of the cost-effectiveness of peginterferon alfa-2b (PEG-IFN alfa-2b) plus ribavirin (RBV) in the treatment of chronic hepatitis C (CHC). A total of 439 references were screened and 11 studies were included. The studies employed decision analytic Markov...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Shepherd J,Jones J

更新日期：2007-12-01 00:00:00

abstract：:This review examines the national trends in out-of-pocket and high economic burden of prescription drug expenditures by elderly people aged 65 years and older. From 1992 to 2000, prescription out-of-pocket drug expenditures increased at an annual rate of 7%. During this period the proportion of elderly without prescri...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Sambamoorthi U,Akincigil A,Wei W,Crystal S

更新日期：2005-06-01 00:00:00

abstract：:Respiratory syncytial virus is the most common cause of bronchiolitis, a lower respiratory tract infection occurring in infancy. It is responsible for several rehospitalizations, substantial morbidity and occasional deaths in the UK every year. Palivizumab is a recombinant monoclonal antibody that has been shown to re...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Embleton ND,Dharmaraj ST,Deshpande S

更新日期：2007-10-01 00:00:00

abstract：:This review addresses hidden costs associated with the Bayer VERSANT assay, Roche AMPLICOR MONITOR test and COBAS AMPLICOR MONITOR test and how these influence the final per reportable cost to a testing laboratory in resource-rich and -poor countries. An in-depth evaluation and recommendation of the most cost-effectiv...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Elbeik T,Chen YM,Soutchkov SV,Loftus RA,Beringer S

更新日期：2003-08-01 00:00:00

abstract：:The aim of this systematic review was to collect all current data on indirect costs related to inflammatory bowel disease as well as assessing homogeneity and comparability, and conducting a meta-analysis. Costs were collected using databases from Medline, Embase and Centre for Reviews and Dissemination databases, the...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Kawalec P,Malinowski KP

更新日期：2015-04-01 00:00:00

abstract：:The goal of asthma management during pregnancy is to keep the mother symptom free and to prevent complications in the fetus. Asthma is a common chronic condition in pregnancy that, if inadequately treated, has the potential to cause adverse effects for both mother and fetus. Aggressive treatment during pregnancy can d...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Streck MR,Blaiss MS

更新日期：2006-02-01 00:00:00

abstract：:Treatment switching has become an important issue in the development and approval of new drugs, particularly in oncology. Randomized controlled trials (RCTs) represent the gold standard for evaluating the effectiveness of interventions, but often patients randomized to the control group are permitted to switch onto th...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Latimer NR

更新日期：2015-01-01 00:00:00

abstract：:Given the lack of evidence from randomized controlled trials and large prospective studies, controversy exists regarding the optimal treatment strategy for early stage prostate cancer. The impact of various treatments on health-related quality of life has become an increasingly important but controversial issue. The l...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： D'haese S,Bottomley A

更新日期：2004-06-01 00:00:00

abstract：:Smoking cessation is the only strategy that has shown a lasting reduction in the decline of lung function in patients with chronic obstructive pulmonary disease. This study aims to evaluate the cost-effectiveness of smoking cessation interventions in patients with chronic obstructive pulmonary disease, to assess the q...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Kirsch F

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:Assess the efficiency of biologic treatment for moderate to severe ulcerative colitis (UC) which are indicated and financed for this pathology by Spain. METHODS:A Markov model was constructed to simulate the progression in a cohort of patients with moderate to severe UC. The perspective chosen was National ...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Trigo-Vicente C,Gimeno-Ballester V,Montoiro-Allué R,López-Del Val A

更新日期：2018-06-01 00:00:00

abstract：:Growing understanding of the mechanisms and epidemiology of neonatal herpes simplex virus acquisition allows for the development of a new management of the pregnant patient, one that will reduce the risk of transmitting herpes to the newborn. Maternal herpes simplex virus infection, especially acquired during pregnanc...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Baker DA

更新日期：2005-12-01 00:00:00

abstract：:Osteoporosis is a public health threat to approximately 44 million individuals in the USA, or 55% of men and women over the age of 50 years. The primary goal of osteoporosis management is to prevent fracture, the most devastating consequence. Risk factors and bone mineral density can be assessed to determine appropria...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Hansen LB

更新日期：2006-10-01 00:00:00

abstract：:This paper reviews the clinical and pharmacoeconomic studies that have been conducted within Europe for patients undergoing elective hip-replacement surgery. Additionally, we offer a perspective on the possible future clinical use of new agents in orthopedic surgery, such as dabigatran and BAY 59-7939 (rivaroxban). Lo...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Ivanovic N,Beinema M,Brouwers JR,Naunton M,Postma MJ

更新日期：2007-02-01 00:00:00

abstract：:Quality-adjusted life-years (QALYs) play an important role in reimbursement decisions when one of the criteria is the cost-effectiveness of the health technology. While for many generic QALYs (e.g., based on the EQ-5D) are viewed as the gold standard, there has been a considerable increase in interest in using conditi...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Petrillo J,Cairns J

更新日期：2008-10-01 00:00:00

abstract：:In this special report, the economics of prior authorization is examined with a focus on the break-even rate that requests are denied. Using a simple theoretical model, comparative static results are derived and used to consider the cost-effectiveness implications of future changes in prior authorization policies. ...

journal_title：Expert review of pharmacoeconomics & outcomes research

authors： Grant WC,Yoder DM,Mullins CD

更新日期：2004-04-01 00:00:00