Abstract:
BACKGROUND:Rotavirus diarrhea is a major health problem among young children worldwide with potential negative impacts on health-related quality of life (HRQoL). This study assessed the impact of rotavirus diarrhea on HRQoL of children and their caregivers. METHODS:We performed a cross-sectional study among 460 hospitalized children with diarrhea aged under 5 years and their family caregivers at three hospitals in Phetchabun province, Thailand during May 2013 and February 2014. The severity of diarrhea was assessed using the Vesikari severity scoring system while the HRQoL was assessed using the EQ-5D-3L. RESULTS:The mean EQ-5D utility of children with all-causes diarrhea was 0.604. The utility of the rotavirus diarrhea group was significantly lower than that of the non-rotavirus diarrhea group (0.593 vs. 0.612; p-value = 0.040). The family caregiver's utility was 0.964 at baseline and significantly decreased to 0.620 (p-value = 0.041) when their children were hospitalized with diarrhea. In multiple regression analyses, severity but not rotavirus infection had significant negative impacts on the utility of both the children and their caregivers. CONCLUSION:Diarrhea, either caused by rotavirus or non-rotavirus infection, resulted in substantial negative impacts on the quality of life of both the children and their caregivers.
journal_name
Expert Rev Pharmacoecon Outcomes Resjournal_title
Expert review of pharmacoeconomics & outcomes researchauthors
Rochanathimoke O,Riewpaiboon A,Postma MJ,Thinyounyong W,Thavorncharoensap Mdoi
10.1080/14737167.2018.1386561subject
Has Abstractpub_date
2018-04-01 00:00:00pages
215-222issue
2eissn
1473-7167issn
1744-8379journal_volume
18pub_type
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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pub_type: 评论,杂志文章
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journal_title:Expert review of pharmacoeconomics & outcomes research
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更新日期:2004-04-01 00:00:00
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,meta分析
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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