Abstract:
:The incidence of melanoma has been climbing steadily since the early 1970s. Although melanoma can be successfully cured by surgical excision in its early stages, it is the most common fatal form of skin cancer. The most critical factors in determining the prognosis for patients with melanoma are primary tumor thickness, ulceration and the status of regional lymph nodes. Surgical treatment alone is inadequate in patients with thick, ulcerated tumors and those with nodal disease, as shown by poor 5-year disease-specific survival rates. Despite the fact that high-dose interferon-alpha has been approved for the treatment of high-risk melanoma by the US Food and Drug Administration and regulatory agencies worldwide, current treatment recommendations vary widely due to the conflicting trial data and significant toxicity and cost associated with high-dose interferon-alpha.
journal_name
Expert Rev Pharmacoecon Outcomes Resjournal_title
Expert review of pharmacoeconomics & outcomes researchauthors
Cormier JN,Xing Y,Ross MI,Cantor SBdoi
10.1586/14737167.4.6.667subject
Has Abstractpub_date
2004-12-01 00:00:00pages
667-76issue
6eissn
1473-7167issn
1744-8379journal_volume
4pub_type
杂志文章abstract::The Institute for Quality and Efficiency in Health Care in Germany makes recommendations for ceiling prices of drugs based on an evaluation of the relationship between costs and effects in each therapeutic area. The analysis requires, when applicable, calculation of savings from avoided clinical events and increased f...
journal_title:Expert review of pharmacoeconomics & outcomes research
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abstract::This review examines the national trends in out-of-pocket and high economic burden of prescription drug expenditures by elderly people aged 65 years and older. From 1992 to 2000, prescription out-of-pocket drug expenditures increased at an annual rate of 7%. During this period the proportion of elderly without prescri...
journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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abstract::Smoking cessation is the only strategy that has shown a lasting reduction in the decline of lung function in patients with chronic obstructive pulmonary disease. This study aims to evaluate the cost-effectiveness of smoking cessation interventions in patients with chronic obstructive pulmonary disease, to assess the q...
journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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abstract::Research on the quality of life (QL) of children/adolescents with psychological disorders has flourished over the last few decades. Given the developmental challenges of QL measurements in pediatric populations, the aim of this study was to ascertain the extent to which a developmental approach to QL assessment has be...
journal_title:Expert review of pharmacoeconomics & outcomes research
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abstract::The goal of asthma management during pregnancy is to keep the mother symptom free and to prevent complications in the fetus. Asthma is a common chronic condition in pregnancy that, if inadequately treated, has the potential to cause adverse effects for both mother and fetus. Aggressive treatment during pregnancy can d...
journal_title:Expert review of pharmacoeconomics & outcomes research
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doi:10.1586/14737167.6.1.67
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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更新日期:2002-02-01 00:00:00
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 社论
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更新日期:2015-01-01 00:00:00
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章
doi:10.1586/14737167.7.4.373
更新日期:2007-08-01 00:00:00
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journal_title:Expert review of pharmacoeconomics & outcomes research
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章,评审
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journal_title:Expert review of pharmacoeconomics & outcomes research
pub_type: 杂志文章
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