Translating evidence into practice.

Abstract:

:Appropriately designed and conducted research is necessary for improving patient care and optimizing health outcomes, but access to best evidence is not enough to make these things happen. In respiratory care, as in other fields, patients do not benefit as much as they should from research findings and evidence-based practice guidelines. Current standards for the diagnosis, staging, and management of chronic obstructive pulmonary disease are based in large part on the results of spirometry, yet most patients carrying this diagnosis have not had this test performed. Despite compelling evidence that it saves lives, reduces complications, and decreases costs in acute respiratory failure complicating chronic obstructive pulmonary disease, noninvasive ventilation is not used in a large proportion of such cases. Lung-protective ventilation for acute lung injury and the acute respiratory distress syndrome also increases survival, decreases complications, and is cost-effective, yet many patients who stand to benefit do not receive it. Clinicians may not be aware of practice guidelines or be familiar with their recommendations; they may not agree with the recommendations, or have insufficient expectation that management according to the guideline will work; they may consider the guideline too complicated or difficult to use in their own practices; patient-related factors may interfere; and changing established practice is often difficult. Overcoming these and other barriers to best practice is the focus of knowledge translation, which recognizes the need for involvement of every aspect of health care and seeks to integrate them effectively. This paper discusses the challenges faced by knowledge translation, provides examples of its successful application in respiratory care, and summarizes what needs to be done if the potential benefits of available evidence are to be realized for both individual patients and the health care system as a whole.

journal_name

Respir Care

journal_title

Respiratory care

authors

Pierson DJ

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

1386-401

issue

10

eissn

0020-1324

issn

1943-3654

journal_volume

54

pub_type

杂志文章
  • Safety and efficacy of short-term intrapulmonary percussive ventilation in patients with bronchiectasis.

    abstract:BACKGROUND:Treatment of bronchiectasis includes drugs, oxygen therapy, and bronchial-clearance maneuvers. OBJECTIVE:To assess the safety and efficacy of intrapulmonary percussive ventilation (IPV) compared to traditional standard chest physical therapy in patients with bronchiectasis and productive cough. METHODS:In ...

    journal_title:Respiratory care

    pub_type: 杂志文章,随机对照试验

    doi:10.4187/respcare.01098

    authors: Paneroni M,Clini E,Simonelli C,Bianchi L,Degli Antoni F,Vitacca M

    更新日期:2011-07-01 00:00:00

  • Weaning from mechanical ventilation: the evidence from clinical research.

    abstract::Mechanical ventilation incurs substantial morbidity, mortality, and costs. Both premature extubation and delayed extubation can cause harm. Therefore, weaning that is both expeditious and safe is highly desirable. The purpose of this review is to summarize the literature related to weaning modes, spontaneous breathing...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Meade MO,Guyatt GH,Cook DJ

    更新日期:2001-12-01 00:00:00

  • Feasibility and Efficacy of Pulsed-Dose Oxygen Delivery During Noninvasive Ventilation.

    abstract:BACKGROUND:It is difficult to apply noninvasive ventilation (NIV) simultaneously with pulsed-dose oxygen delivery. We evaluated the feasibility and efficacy of pulsed-dose oxygen delivery during NIV. METHODS:A bench study was conducted using a simulated lung during NIV, with a breathing frequency of 10 or 20 breaths/m...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06922

    authors: Li LL,Yang HY,Jin H,Dai B,Peng Y,Tan W

    更新日期:2020-09-01 00:00:00

  • Beliefs and Attitudes Associated With Hookah Smoking Among a United States College Population.

    abstract:BACKGROUND:This study explores the differences among smokers of waterpipe tobacco in a college population to better inform campaigns to curb waterpipe use. METHODS:Participants included undergraduate and graduate students attending a liberal arts university in Florida. E-mail-based, cross-sectional surveys were collec...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.05069

    authors: Martinasek MP,Haddad LG,Wheldon CW,Barnett TE

    更新日期:2017-03-01 00:00:00

  • Nintedanib: a novel therapeutic approach for idiopathic pulmonary fibrosis.

    abstract::Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic lung disease with no clear etiology and few therapeutic options. Growth factors that act as mediators in the development of this disease might be important therapeutic targets. Nintedanib is a triple-tyrosine kinase inhibitor and a potent antagoni...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:10.4187/respcare.03023

    authors: Dimitroulis IA

    更新日期:2014-09-01 00:00:00

  • Modification of an external low-pressure ventilator alarm to allow its remote use for isolated patients.

    abstract::The problem of patients in isolation becoming disconnected from their ventilator systems is a serious one, as the closed doors of an isolation room usually prevent hospital personnel outside the room from hearing or seeing standard ventilator alarms To overcome this potentially life-threatening problem, we modified a ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Morganstern MA,Karpel SK

    更新日期:1986-05-01 00:00:00

  • Bacterial Contamination of Circuit Inner Surfaces After High-Flow Oxygen Therapy.

    abstract:BACKGROUND:During high-flow oxygen therapy, heated humidified gas is delivered at high flow. Although the warmth and humidity of this gas facilitates mucociliary function in the lower airway, warm and humid conditions also promote bacterial growth. Bacterial contamination of high-flow oxygen therapy circuits has not be...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06299

    authors: Onodera M,Nakataki E,Nakanishi N,Itagaki T,Sato M,Oto J,Nishimura M

    更新日期:2019-05-01 00:00:00

  • Usefulness of Oscillations Added to Mechanical In-Exsufflation in Amyotrophic Lateral Sclerosis.

    abstract:BACKGROUND:Assisted coughing via mechanical in-exsufflation (MI-E) is a first-line treatment for secretion management in patients with amyotrophic lateral sclerosis (ALS) with unassisted CPF < 4.25 L/s. Some devices enable oscillations to be added to MI-E (MI-E+O). We sought to determine whether adding oscillations to ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.07202

    authors: Sancho J,Burés E,Ferrer S,Bondía E,Servera E

    更新日期:2020-05-01 00:00:00

  • Inspiratory flow-volume curve evaluation for detecting upper airway disease.

    abstract:BACKGROUND:The 2005 American Thoracic Society/European Respiratory Society guidelines on spirometry emphasize examination of the inspiratory curve of the flow-volume loop for evidence of intrathoracic or extrathoracic upper airway obstruction. We sought to determine how frequently evaluations are performed for abnormal...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Sterner JB,Morris MJ,Sill JM,Hayes JA

    更新日期:2009-04-01 00:00:00

  • Should Aerosolized Antibiotics Be Used to Treat Ventilator-Associated Pneumonia?

    abstract::In patients with ventilator-associated pneumonia, systemic use of antibiotics is the cornerstone of medical management. Supplemental use of aerosolized antibiotics with intravenous antibiotics in both experimental and clinical studies has been shown to have the following pharmacologic benefits: (1) aerosolized antibio...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:10.4187/respcare.04748

    authors: Zhang C,Berra L,Klompas M

    更新日期:2016-06-01 00:00:00

  • Longitudinal evaluation of compressor/nebulizer performance.

    abstract:BACKGROUND:Inhaled medications are the mainstay of treatment for maintenance of lung health in patients with cystic fibrosis (CF). Compressor/nebulizer units are used an average of 100-120 min/d by patients with CF. Each compressor/nebulizer has unique flow/pressure characteristics that affect particle size distributio...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.02776

    authors: Awad S,Williams DK,Berlinski A

    更新日期:2014-07-01 00:00:00

  • Effectiveness of a Pulmonary Rehabilitation Program on Persistent Asthma Stratified for Severity.

    abstract:BACKGROUND:Asthma is defined by airway inflammation associated with various respiratory symptoms, and pharmacologic treatment is based on inhaled corticosteroids and bronchodilators. Physical activity, educational training, nutritional support, and psychological counseling are considered part of non-pharmacologic treat...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06761

    authors: Zampogna E,Paneroni M,Cherubino F,Pignatti P,Rudi M,Casu G,Vitacca M,Spanevello A,Visca D

    更新日期:2019-12-01 00:00:00

  • Strategies for screening for chronic obstructive pulmonary disease.

    abstract::Chronic obstructive pulmonary disease is easily detected in its preclinical phase, using office spirometry. Successful smoking cessation prevents further disease progression in most patients. Spirometry measures the ratio of the forced expiratory volume in the first second to the forced vital capacity (FEV(1)/FVC), wh...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Enright PL,Kaminsky DA

    更新日期:2003-12-01 00:00:00

  • Hypoxemia during sleep in patients with chronic obstructive pulmonary disease: significance, detection, and effects of therapy.

    abstract::NOD is a common event in patients with symptomatic COPD who are not hypoxemic while awake. Up to 45% of these patients may have significant oxyhemoglobin desaturation during sleep, and most have evidence of pulmonary arterial hypertension. Although intuitively it would seem that supplemental oxygen during sleep should...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: O'Donohue WJ Jr,Bowman TJ

    更新日期:2000-02-01 00:00:00

  • Prognostic value of plateau pressure below 30 cm H2O in septic subjects with acute respiratory failure.

    abstract:BACKGROUND:Ventilation with low tidal volume is recommended for patients with acute lung injury. Current guidelines suggest limiting plateau pressure (Pplat) to < 30 cm H2O for septic patients needing mechanical ventilation. The aim of this study was to determine whether Pplat within the first 24 h of ICU admission is ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.03138

    authors: Chan MC,Tseng JS,Chiu JT,Hsu KH,Shih SJ,Yi CY,Wu CL,Kou YR

    更新日期:2015-01-01 00:00:00

  • Comparison of different exercise tests in assessing outcomes of pulmonary rehabilitation.

    abstract:INTRODUCTION:Common modalities of clinical exercise testing for outcome measurement after pulmonary rehabilitation (PR) include walk tests, progressive cycle ergometry, and cycle endurance testing. We hypothesized that patients' responses to PR, as measured by those 3 tests, are differentially correlated, and we design...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Ong KC,Chong WF,Soh C,Earnest A

    更新日期:2004-12-01 00:00:00

  • The impact of computer-age technology on respiratory therapy.

    abstract::Computer-age technology is changing the face of respiratory therapy as it is that of nearly every other technical field. In some hospital respiratory therapy departments computers are presently being used for a wide range of functions such as blood gas result reporting, billing, budgeting, purchasing, hemodynamic calc...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: McPeck M

    更新日期:1982-07-01 00:00:00

  • Evaluation of the ventilator-user interface of 2 new advanced compact transport ventilators.

    abstract:BACKGROUND:Mechanical ventilation during patient transport frequently utilizes compact portable pneumatic ventilators that have limited ventilator-settings options. New advanced transport ventilators should yield quality improvements, but their user-friendliness needs to be tested. OBJECTIVE:To evaluate the ventilator...

    journal_title:Respiratory care

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Templier F,Miroux P,Dolveck F,Descatha A,Goddet NS,Jeleff C,Baer M,Chauvin M,Brochard L,Fletcher D

    更新日期:2007-12-01 00:00:00

  • Clinical Characteristics, Respiratory Mechanics and Outcomes in Critically Ill Subjects with COVID-19 Infection in an Underserved Urban Population.

    abstract:BACKGROUND:The COVID-19 outbreak in the United States has disproportionately affected African-Americans, but little is known about the factors that underlie this observation. Herein, we describe these associations with mortality in a largely minority underserved population. METHODS:This single center retrospective obs...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.08319

    authors: Chaudhary S,Benzaquen S,Woo JG,Rubinstein J,Matta A,Albano J,De Joy R III,Lo KB,Patarroyo-Aponte G

    更新日期:2021-01-14 00:00:00

  • Determinants of patient adherence to an aerosol regimen.

    abstract::Patient adherence with prescribed inhaled therapy is related to morbidity and mortality. The terms "compliance" and "adherence" are used in the literature to describe agreement between prescribed medication and patient practice, with "adherence" implying active patient participation. Patient adherence with inhaled med...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Rau JL

    更新日期:2005-10-01 00:00:00

  • Positive expiratory pressure changes aerosol distribution in patients with cystic fibrosis.

    abstract:HYPOTHESIS:We hypothesized that aerosol distribution in the lungs of patients with cystic fibrosis changes with positive expiratory pressure (PEP). METHODS:Eight patients were randomized to one of 2 conditions. On one study day, patients inhaled saline aerosol containing 99mtechnetium generated by a Pari LC Plus nebul...

    journal_title:Respiratory care

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Laube BL,Geller DE,Lin TC,Dalby RN,Diener-West M,Zeitlin PL

    更新日期:2005-11-01 00:00:00

  • Randomized controlled trial of a breath-actuated nebulizer in pediatric asthma patients in the emergency department.

    abstract:BACKGROUND:Bronchodilator treatment for asthma can be provided with various aerosol-generating devices and methods. There have been no randomized trials of a breath-actuated nebulizer versus continuous 1-hour nebulization and/or small-volume constant-output nebulizer in pediatric asthma patients. METHODS:We conducted ...

    journal_title:Respiratory care

    pub_type: 杂志文章,随机对照试验

    doi:10.4187/respcare.00142

    authors: Sabato K,Ward P,Hawk W,Gildengorin V,Asselin JM

    更新日期:2011-06-01 00:00:00

  • Spirometry training does not guarantee valid results.

    abstract:BACKGROUND:Many healthcare professionals performing spirometry in primary care have had less than half a day's training in spirometry practice, and the validity of the test results is questionable. Longer training periods, with or without follow-up training, may improve test validity. OBJECTIVE:To determine if a 14-ho...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Borg BM,Hartley MF,Fisher MT,Thompson BR

    更新日期:2010-06-01 00:00:00

  • Impact of Home Oxygen Therapy on the Level of Physical Activities in Daily Life in Subjects With COPD.

    abstract:BACKGROUND:Chronic hypoxemia in patients with COPD is a limiting factor that is associated with disease progression and significantly contributes to decreased physical activity. Although correction of hypoxemia results in physiological improvements, oxygen therapy may be related to social isolation and inactivity. Howe...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06206

    authors: Cani KC,Matte DL,Silva IJCS,Gulart AA,Karloh M,Mayer AF

    更新日期:2019-11-01 00:00:00

  • Validation of the Asthma Quality of Life Questionnaire with momentary assessments of symptoms and functional limitations in patient daily life.

    abstract:BACKGROUND:The ecological momentary assessment method may collect more accurate data about a patient's symptoms and functioning during the patient's normal daily life than does a retrospective measurement method such as the standardized Asthma Quality of Life Questionnaire (AQLQ-S), which relies on the patient's recoll...

    journal_title:Respiratory care

    pub_type: 临床试验,杂志文章

    doi:

    authors: Everhart RS,Smyth JM,Santuzzi AM,Fiese BH

    更新日期:2010-04-01 00:00:00

  • Respiratory controversies in the critical care setting. Do the NIH ARDS Clinical Trials Network PEEP/FIO2 tables provide the best evidence-based guide to balancing PEEP and FIO2 settings in adults?

    abstract::Positive end-expiratory pressure (PEEP) and inspired oxygen fraction (F(IO(2))) are the primary means of improving P(aO(2)) during mechanical ventilation. Patients with acute respiratory distress syndrome (ARDS) typically present with a large intrapulmonary shunt, which makes even high F(IO(2)) ineffective in improvin...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Kallet RH,Branson RD

    更新日期:2007-04-01 00:00:00

  • The invasive (quantitative) diagnosis of ventilator-associated pneumonia.

    abstract::Although appropriate antibiotics may improve survival in patients with bacterial pneumonia, use of empirical broad-spectrum antibiotics in patients without infection is potentially harmful, facilitating colonization and superinfection with multiresistant microorganisms. Invasive diagnostic methods, including bronchoal...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Chastre J,Combes A,Luyt CE

    更新日期:2005-06-01 00:00:00

  • Perceived benefits of the use of learning contracts to guide clinical education in respiratory care students.

    abstract:BACKGROUND:The benefits of contract learning have been identified in the literature as increased individualization to meet the student's individual needs, promotion of learner independence, and development of lifelong learning behaviors among students. METHODS:I used an "action research" approach to implement the cont...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Rye KJ

    更新日期:2008-11-01 00:00:00

  • Pediatric acute respiratory distress syndrome.

    abstract::The data available to guide clinical management of acute lung injury and acute respiratory distress syndrome are much more limited for infants and children than for adult patients. This paper reviews the available medical data and the pertinent physiology on the management of pediatric patients with acute lung injury...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.01515

    authors: Cheifetz IM

    更新日期:2011-10-01 00:00:00

  • Persistent Empiric COPD Diagnosis and Treatment After Pulmonary Function Test Showed No Obstruction.

    abstract:BACKGROUND:Health-care providers often diagnose and empirically treat COPD without a confirmative pulmonary function test (PFT) or even despite a PFT that is not diagnostic of obstructive lung disease. We hypothesized that a portion of patients continue to carry a persistent empiric COPD diagnosis and receive treatment...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.04647

    authors: Fortis S,Corazalla EO,Jacobs DR Jr,Kim HJ

    更新日期:2016-09-01 00:00:00