Zooplankton diversity analysis through single-gene sequencing of a community sample.

abstract：BACKGROUND:The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines to be interrogated at genome-wide scale. However, multiple issues, such as off-target effects or low efficacies in knocking down ce...

journal_title：BMC genomics

authors： Wang L,Tu Z,Sun F

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:Scaleless (sc/sc) chickens carry a single recessive mutation that causes a lack of almost all body feathers, as well as foot scales and spurs, due to a failure of skin patterning during embryogenesis. This spontaneous mutant line, first described in the 1950s, has been used extensively to explore the tissue ...

journal_title：BMC genomics

authors： Wells KL,Hadad Y,Ben-Avraham D,Hillel J,Cahaner A,Headon DJ

更新日期：2012-06-19 00:00:00

abstract：BACKGROUND:Leishmania (L) are intracellular protozoan parasites that are able to survive and replicate within the harsh and potentially hostile phagolysosomal environment of mammalian mononuclear phagocytes. A complex interplay then takes place between the macrophage (MPhi) striving to eliminate the pathogen and the pa...

journal_title：BMC genomics

authors： Guerfali FZ,Laouini D,Guizani-Tabbane L,Ottones F,Ben-Aissa K,Benkahla A,Manchon L,Piquemal D,Smandi S,Mghirbi O,Commes T,Marti J,Dellagi K

更新日期：2008-05-21 00:00:00

abstract：BACKGROUND:Abnormalities of pre-mRNA splicing are increasingly recognized as an important mechanism through which gene mutations cause disease. However, apart from the mutations in the donor and acceptor sites, the effects on splicing of other sequence variations are difficult to predict. Loosely defined exonic and int...

journal_title：BMC genomics

authors： Lastella P,Surdo NC,Resta N,Guanti G,Stella A

更新日期：2006-09-22 00:00:00

abstract：BACKGROUND:Most microbial eukaryotes are uncultivated and thus poorly suited to standard genomic techniques. This is the case for Polykrikos lebouriae, a dinoflagellate with ultrastructurally aberrant plastids. It has been suggested that these plastids stem from a novel symbiosis with either a diatom or haptophyte, but...

journal_title：BMC genomics

authors： Gavelis GS,White RA,Suttle CA,Keeling PJ,Leander BS

更新日期：2015-07-17 00:00:00

abstract：BACKGROUND:Plant nucleotide-binding site (NBS)-leucine-rich repeat (LRR) proteins encoded by resistance genes play an important role in the responses of plants to various pathogens, including viruses, bacteria, fungi, and nematodes. In this study, a comprehensive analysis of NBS-encoding genes within the whole cucumber...

journal_title：BMC genomics

authors： Wan H,Yuan W,Bo K,Shen J,Pang X,Chen J

更新日期：2013-02-19 00:00:00

abstract：BACKGROUND:Use of genomic tools to characterize wildlife populations has increased in recent years. In the past, genetic characterization has been accomplished with more traditional genetic tools (e.g., microsatellites). The explosion of genomic methods and the subsequent creation of large SNP datasets has led to the p...

journal_title：BMC genomics

authors： Zimmerman SJ,Aldridge CL,Oyler-McCance SJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The NBS disease-related gene family coordinates the inherent immune system in plants in response to pathogen infections. Previous studies have identified NBS-encoding genes in Pyrus bretschneideri ('Dangshansuli', an Asian pear) and Pyrus communis ('Bartlett', a European pear) genomes, but the patterns of ge...

journal_title：BMC genomics

authors： Sun M,Zhang M,Singh J,Song B,Tang Z,Liu Y,Wang R,Qin M,Li J,Khan A,Wu J

更新日期：2020-11-19 00:00:00

abstract：BACKGROUND:Castor oil is the only commercial source of hydroxy fatty acid that has industrial value. The production of castor oil is hampered by the presence of the toxin ricin in its seed. Lesquerella seed also accumulates hydroxy fatty acid and is free of ricin, and thus it is being developed as a new crop for hydrox...

journal_title：BMC genomics

authors： Kim HU,Chen GQ

更新日期：2015-03-24 00:00:00

abstract：BACKGROUND:Brucella abortus is an intracellular zoonotic pathogen which causes undulant fever, endocarditis, arthritis and osteomyelitis in human and abortion and infertility in cattle. This bacterium is able to invade and replicate in host macrophage instead of getting removed by this defense mechanism. Therefore, und...

journal_title：BMC genomics

authors： Cha SB,Lee WJ,Shin MK,Jung MH,Shin SW,Yoo AN,Kim JW,Yoo HS

更新日期：2013-06-27 00:00:00

abstract：BACKGROUND:Bacteriophages are the most abundant and diverse entities in the biosphere, and this diversity is driven by constant predator-prey evolutionary dynamics and horizontal gene transfer. Phage genome sequences are under-sampled and therefore present an untapped and uncharacterized source of genetic diversity, ty...

journal_title：BMC genomics

authors： Oliveira H,Sampaio M,Melo LDR,Dias O,Pope WH,Hatfull GF,Azeredo J

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Soybean cyst nematode (SCN) is the most economically devastating pathogen of soybean. Two resistance loci, Rhg1 and Rhg4 primarily contribute resistance to SCN race 3 in soybean. Peking and PI 88788 are the two major sources of SCN resistance with Peking requiring both Rhg1 and Rhg4 alleles and PI 88788 only...

journal_title：BMC genomics

authors： Shi Z,Liu S,Noe J,Arelli P,Meksem K,Li Z

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Second generation sequencing has permitted detailed sequence characterisation at the whole genome level of a growing number of non-model organisms, but the data produced have short read-lengths and biased genome coverage leading to fragmented genome assemblies. The PacBio RS long-read sequencing platform off...

journal_title：BMC genomics

authors： Ferrarini M,Moretto M,Ward JA,Šurbanovski N,Stevanović V,Giongo L,Viola R,Cavalieri D,Velasco R,Cestaro A,Sargent DJ

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The Zap1 transcription factor is a central player in the response of yeast to changes in zinc status. We previously used transcriptome profiling with DNA microarrays to identify 46 potential Zap1 target genes in the yeast genome. In this new study, we used complementary methods to identify additional Zap1 ta...

journal_title：BMC genomics

authors： Wu CY,Bird AJ,Chung LM,Newton MA,Winge DR,Eide DJ

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Compared to other ascomycetes, the barley powdery mildew pathogen Blumeria graminis f.sp. hordei (Bgh) has a large genome (ca. 120 Mbp) that harbors a relatively small number of protein-coding genes (ca. 6500). This genomic assemblage is thought to be the result of numerous gene losses, which likely represen...

journal_title：BMC genomics

authors： Kusch S,Ahmadinejad N,Panstruga R,Kuhn H

更新日期：2014-10-02 00:00:00

abstract：BACKGROUND:Transcription factor (TF) GAMYB, belonging to MYB family (named after the gene of the avian myeloblastosis virus) is a master gibberellin (GA)-induced regulatory protein that is crucial for development and germination of cereal grain and involved in anther formation. It activates many genes including high-mo...

journal_title：BMC genomics

authors： Bienias A,Góralska M,Masojć P,Milczarski P,Myśków B

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Magnaporthe oryzae (anamorph Pyricularia oryzae) is the causal agent of blast disease of Poaceae crops and their wild relatives. To understand the genetic mechanisms that drive host specialization of M. oryzae, we carried out whole genome resequencing of four M. oryzae isolates from rice (Oryza sativa), one ...

journal_title：BMC genomics

authors： Yoshida K,Saunders DG,Mitsuoka C,Natsume S,Kosugi S,Saitoh H,Inoue Y,Chuma I,Tosa Y,Cano LM,Kamoun S,Terauchi R

更新日期：2016-05-18 00:00:00

abstract：BACKGROUND:The Pacific oyster Crassostrea gigas is an important fishery resource that is sensitive to temperature fluctuations. Thus, it has evolved a protection mechanism against heat stress by increasing the expression of the gene coding for heat shock protein (HSP) 70 under elevated temperatures. In other animals, h...

journal_title：BMC genomics

authors： Liu Y,Li L,Huang B,Wang W,Zhang G

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:Common Pekin and Muscovy ducks and their intergeneric hinny and mule hybrids have different abilities for fatty liver production. RNA-Seq analyses from the liver of these different genetic types fed ad libitum or overfed would help to identify genes with different response to overfeeding between them. Howeve...

journal_title：BMC genomics

authors： Liu X,Hérault F,Diot C,Corre E

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:Cryptic unstable transcripts (CUTs) are a largely unexplored class of nuclear exosome degraded, non-coding RNAs in budding yeast. It is highly debated whether CUT transcription has a functional role in the cell or whether CUTs represent noise in the yeast transcriptome. We sought to ascertain the extent of c...

journal_title：BMC genomics

authors： Vera JM,Dowell RD

更新日期：2016-04-26 00:00:00

abstract：BACKGROUND:A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis. However, the RNA-edit...

journal_title：BMC genomics

authors： Qiu S,Li W,Xiong H,Liu D,Bai Y,Wu K,Zhang X,Yang H,Ma K,Hou Y,Li B

更新日期：2016-09-29 00:00:00

abstract：BACKGROUND:Atlantic salmon production in Tasmania (Southern Australia) occurs near the upper limits of the species thermal tolerance. Summer water temperatures can average over 19 °C over several weeks and have negative effects on performance and health. Liver tissue exerts important metabolic functions in thermal adap...

journal_title：BMC genomics

authors： Nuez-Ortín WG,Carter CG,Nichols PD,Cooke IR,Wilson R

更新日期：2018-02-12 00:00:00

abstract：BACKGROUND:Neighboring gene pairs in the genome of Saccharomyces cerevisiae have a tendency to be expressed at the same time. The distribution of histone modifications along chromatin fibers is suggested to be an important mechanism responsible for such coexpression. However, the extent of the contribution of histone m...

journal_title：BMC genomics

authors： Deng Y,Dai X,Xiang Q,Dai Z,He C,Wang J,Feng J

更新日期：2010-10-09 00:00:00

abstract：BACKGROUND:Maternal undernutrition leads to an increased risk of metabolic disorders in offspring including obesity and insulin resistance, thought to be due to a programmed thrifty phenotype which is inappropriate for a subsequent richer nutritional environment. In a rat model, both male and female offspring of undern...

journal_title：BMC genomics

authors： Ellis PJ,Morris TJ,Skinner BM,Sargent CA,Vickers MH,Gluckman PD,Gilmour S,Affara NA

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:Cultivated watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus] is an important agriculture crop world-wide. The fruit of watermelon undergoes distinct stages of development with dramatic changes in its size, color, sweetness, texture and aroma. In order to better understand the genetic and m...

journal_title：BMC genomics

authors： Guo S,Liu J,Zheng Y,Huang M,Zhang H,Gong G,He H,Ren Y,Zhong S,Fei Z,Xu Y

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:Avian infectious bronchitis virus (IBV) is a gamma coronavirus that severely affects the poultry industry worldwide. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs with a length of more than 200 nucleotides, have been recently recognized as pivotal factors in the pathogenesis of viral infections...

journal_title：BMC genomics

authors： Li H,Cui P,Fu X,Zhang L,Yan W,Zhai Y,Lei C,Wang H,Yang X

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Macrobrachium rosenbergii, is one of a major freshwater prawn species cultured in Southeast Asia. White tail disease (WTD), caused by Macrobrachium rosenbergii nodavirus (MrNV), is a serious problem in farm cultivation and is responsible for up to 100% mortality in the post larvae stage. Molecular data on ho...

journal_title：BMC genomics

authors： Pasookhush P,Hindmarch C,Sithigorngul P,Longyant S,Bendena WG,Chaivisuthangkura P

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Homologous recombination is the key process that generates genetic diversity and drives evolution. SPO11 protein triggers recombination by introducing DNA double stranded breaks at discreet areas of the genome called recombination hotspots. The hotspot locations are largely determined by the DNA binding spec...

journal_title：BMC genomics

authors： Smagulova F,Brick K,Pu Y,Sengupta U,Camerini-Otero RD,Petukhova GV

更新日期：2013-07-22 00:00:00

abstract：BACKGROUND:Recent studies have shown that human populations have experienced a complex demographic history, including a recent epoch of rapid population growth that led to an excess in the proportion of rare genetic variants in humans today. This excess can impact the burden of private mutations for each individual, de...

journal_title：BMC genomics

authors： Gao F,Keinan A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Ecological studies routinely show genotype-genotype interactions between insects and their parasites. The mechanisms behind these interactions are not clearly understood. Using the bumblebee Bombus terrestris/trypanosome Crithidia bombi model system (two bumblebee colonies by two Crithidia strains), we have ...

journal_title：BMC genomics

authors： Riddell CE,Lobaton Garces JD,Adams S,Barribeau SM,Twell D,Mallon EB

更新日期：2014-11-27 00:00:00