Differential control of Zap1-regulated genes in response to zinc deficiency in Saccharomyces cerevisiae.

abstract：BACKGROUND:Fasting induces specific molecular and metabolic adaptions in most organisms. In biomedical research fasting is used in metabolic studies to synchronize nutritional states of study subjects. Because there is a lack of standardization for this procedure, we need a deeper understanding of the dynamics and the ...

journal_title：BMC genomics

authors： Schupp M,Chen F,Briggs ER,Rao S,Pelzmann HJ,Pessentheiner AR,Bogner-Strauss JG,Lazar MA,Baldwin D,Prokesch A

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:Moraxella catarrhalis is an important pathogen that often causes otitis media in children, a disease that is not currently vaccine preventable. Asymptomatic colonisation of the human upper respiratory tract is common and lack of clearance by the immune system is likely due to the emergence of seroresistant g...

journal_title：BMC genomics

authors： Ariff A,Wise MJ,Kahler CM,Tay CY,Peters F,Perkins TT,Chang BJ

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:The genome of pathogenic Leptospira interrogans contains two chromosomes. Plasmids and prophages are known to play specific roles in gene transfer in bacteria and can potentially serve as efficient genetic tools in these organisms. Although plasmids and prophage remnants have recently been reported in Leptos...

journal_title：BMC genomics

authors： Zhu W,Wang J,Zhu Y,Tang B,Zhang Y,He P,Zhang Y,Liu B,Guo X,Zhao G,Qin J

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:The Iberian lynx (Lynx pardinus) has been acknowledged as the most endangered felid species in the world. An intense contraction and fragmentation during the twentieth century left less than 100 individuals split in two isolated and genetically eroded populations by 2002. Genetic monitoring and management so...

journal_title：BMC genomics

authors： Kleinman-Ruiz D,Martínez-Cruz B,Soriano L,Lucena-Perez M,Cruz F,Villanueva B,Fernández J,Godoy JA

更新日期：2017-07-21 00:00:00

abstract：BACKGROUND:Petal nectar spurs, which facilitate pollination through animal attraction and pollen placement, represent a key innovation promoting diversification in the genus Aquilegia (Ranunculaceae). Identifying the genetic components that contribute to the development of these three-dimensional structures will inform...

journal_title：BMC genomics

authors： Ballerini ES,Kramer EM,Hodges SA

更新日期：2019-08-22 00:00:00

abstract：BACKGROUND:In many microbial genomes, a strong preference for a small number of codons can be observed in genes whose products are needed by the cell in large quantities. This codon usage bias (CUB) improves translational accuracy and speed and is one of several factors optimizing cell growth. Whereas CUB and the overr...

journal_title：BMC genomics

authors： von Mandach C,Merkl R

更新日期：2010-11-04 00:00:00

abstract：BACKGROUND:Preterm birth (PTB), birth at <37 weeks of gestation, is a significant global public health problem. World-wide, about 15 million babies are born preterm each year resulting in more than a million deaths of children. Preterm neonates are more prone to problems and need intensive care hospitalization. Health ...

journal_title：BMC genomics

authors： Sheikh IA,Ahmad E,Jamal MS,Rehan M,Assidi M,Tayubi IA,AlBasri SF,Bajouh OS,Turki RF,Abuzenadah AM,Damanhouri GA,Beg MA,Al-Qahtani M

更新日期：2016-10-17 00:00:00

abstract：BACKGROUND:Sugarcane smut is a fungal disease caused by Sporisorium scitamineum. Cultivation of smut-resistant sugarcane varieties is the most effective way to control this disease. The interaction between sugarcane and S. scitamineum is a complex network system. However, to date, there is no report on the identificati...

journal_title：BMC genomics

authors： Su Y,Xiao X,Ling H,Huang N,Liu F,Su W,Zhang Y,Xu L,Muhammad K,Que Y

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Gymnosporangium spp. are fungal plant pathogens causing rust disease and most of them are known to infect two different host plants (heteroecious) with four spore stages (demicyclic). In the present study, we sequenced the transcriptome of G. japonicum teliospores on its host plant Juniperus chinensis and we...

journal_title：BMC genomics

authors： Tao SQ,Cao B,Morin E,Liang YM,Duplessis S

更新日期：2019-10-09 00:00:00

abstract：BACKGROUND:Many tools exist to predict structural variants (SVs), utilizing a variety of algorithms. However, they have largely been developed and tested on human germline or somatic (e.g. cancer) variation. It seems appropriate to exploit this wealth of technology available for humans also for other species. Objective...

journal_title：BMC genomics

authors： Leung WY,Marschall T,Paudel Y,Falquet L,Mei H,Schönhuth A,Maoz Moss TY

更新日期：2015-03-25 00:00:00

abstract：BACKGROUND:The genomewide evaluation of genetic epistasis is a computationally demanding task, and a current challenge in Genetics. HFCC (Hypothesis-Free Clinical Cloning) is one of the methods that have been suggested for genomewide epistasis analysis. In order to perform an exhaustive search of epistasis, HFCC has im...

journal_title：BMC genomics

authors： Gayán J,González-Pérez A,Ruiz A

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:Banana wilt disease, caused by Fusarium oxysporum f. sp. cubense Tropical Race 4 (Foc TR4), is one of the most devastating diseases in banana (Musa spp.). Foc is a soil borne pathogen that causes rot of the roots or wilt of leaves by colonizing the xylem vessels. The dual RNA sequencing is used to simultaneo...

journal_title：BMC genomics

authors： Li W,Wang X,Li C,Sun J,Li S,Peng M

更新日期：2019-06-24 00:00:00

abstract：BACKGROUND:Complete mitochondrial genomes are much better suited for the taxonomic identification and phylogenetic studies of nematodes than morphology or traditionally-used molecular markers, but they remain unavailable for the entire Camallanidae family (Chromadorea). As the only published mitogenome in the Camallani...

journal_title：BMC genomics

authors： Zou H,Jakovlić I,Chen R,Zhang D,Zhang J,Li WX,Wang GT

更新日期：2017-11-02 00:00:00

abstract：BACKGROUND:Improving fiber quality is a major challenge in cotton breeding, since the molecular basis of fiber quality traits is poorly understood. Fine mapping and candidate gene prediction of quantitative trait loci (QTL) controlling cotton fiber quality traits can help to elucidate the molecular basis of fiber quali...

journal_title：BMC genomics

authors： Liu D,Zhang J,Liu X,Wang W,Liu D,Teng Z,Fang X,Tan Z,Tang S,Yang J,Zhong J,Zhang Z

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders such as the Williams-B...

journal_title：BMC genomics

authors： Ebert G,Steininger A,Weißmann R,Boldt V,Lind-Thomsen A,Grune J,Badelt S,Heßler M,Peiser M,Hitzler M,Jensen LR,Müller I,Hu H,Arndt PF,Kuss AW,Tebel K,Ullmann R

更新日期：2014-06-29 00:00:00

abstract：BACKGROUND:The advance of high-throughput sequencing has made it possible to obtain new transcriptomes and study splicing mechanisms in non-model organisms. In these studies, there is often a need to investigate the transcriptomes of two related organisms at the same time in order to find the similarities and differenc...

journal_title：BMC genomics

authors： Fu S,Tarone AM,Sze SH

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The steroid hormone environment in healthy horses seems to have a significant impact on the efficiency of their uterine immune response. The objective of this study was to characterize the changes in gene expression in the equine endometrium in response to the introduction of bacterial pathogens and the infl...

journal_title：BMC genomics

authors： Marth CD,Young ND,Glenton LY,Noden DM,Browning GF,Krekeler N

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Fluctuations in external salinity force eukaryotic cells to respond by changes in the gene expression of proteins acting in protective biochemical processes, thus counteracting the changing osmotic pressure. The high-osmolarity glycerol (HOG) signaling pathway is essential for the efficient up-regulation of ...

journal_title：BMC genomics

authors： Vaupotic T,Plemenitas A

更新日期：2007-08-16 00:00:00

abstract：BACKGROUND:Mouse has served as an excellent model for studying human development and diseases due to its similarity to human. Advances in transgenic and knockout studies in mouse have dramatically strengthened the use of this model and significantly improved our understanding of gene function during development in the ...

journal_title：BMC genomics

authors： Xue L,Cai JY,Ma J,Huang Z,Guo MX,Fu LZ,Shi YB,Li WX

更新日期：2013-08-20 00:00:00

abstract：BACKGROUND:Obesity affects quality of life and life expectancy and is associated with cardiovascular disorders, cancer, diabetes, reproductive disorders in women, prostate diseases in men, and congenital anomalies in children. The use of single nucleotide polymorphism (SNP) markers of diseases and drug responses (i.e.,...

journal_title：BMC genomics

authors： Arkova OV,Ponomarenko MP,Rasskazov DA,Drachkova IA,Arshinova TV,Ponomarenko PM,Savinkova LK,Kolchanov NA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Spinach downy mildew caused by the oomycete Peronospora effusa is a significant burden on the expanding spinach production industry, especially for organic farms where synthetic fungicides cannot be deployed to control the pathogen. P. effusa is highly variable and 15 new races have been recognized in the pa...

journal_title：BMC genomics

authors： Fletcher K,Klosterman SJ,Derevnina L,Martin F,Bertier LD,Koike S,Reyes-Chin-Wo S,Mou B,Michelmore R

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:Avian infectious bronchitis virus (IBV) is a gamma coronavirus that severely affects the poultry industry worldwide. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs with a length of more than 200 nucleotides, have been recently recognized as pivotal factors in the pathogenesis of viral infections...

journal_title：BMC genomics

authors： Li H,Cui P,Fu X,Zhang L,Yan W,Zhai Y,Lei C,Wang H,Yang X

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:One of the most fundamental and challenging tasks in bio-informatics is to identify related sequences and their hidden biological significance. The most popular and proven best practice method to accomplish this task is aligning multiple sequences together. However, multiple sequence alignment is a computing...

journal_title：BMC genomics

authors： Nguyen KD,Pan Y,Nong G

更新日期：2011-12-23 00:00:00

abstract：BACKGROUND:We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating the gene encoding a chimeric hexose transporter, Tm6*, into the genome of an hxt null yeast. Subsequently we transferred this respiratory phenotype in the presence of up to 50 g/L glucose to a yeast strai...

journal_title：BMC genomics

authors： Bonander N,Ferndahl C,Mostad P,Wilks MD,Chang C,Showe L,Gustafsson L,Larsson C,Bill RM

更新日期：2008-07-31 00:00:00

abstract：BACKGROUND:Thoroughbred horses are the most expensive domestic animals, and their running ability and knowledge about their muscle-related diseases are important in animal genetics. While the horse reference genome is available, there has been no large-scale functional annotation of the genome using expressed genes der...

journal_title：BMC genomics

authors： Park KD,Park J,Ko J,Kim BC,Kim HS,Ahn K,Do KT,Choi H,Kim HM,Song S,Lee S,Jho S,Kong HS,Yang YM,Jhun BH,Kim C,Kim TH,Hwang S,Bhak J,Lee HK,Cho BW

更新日期：2012-09-12 00:00:00

abstract：BACKGROUND:Bifidobacteria are commonly found as part of the microbiota of the gastrointestinal tract (GIT) of a broad range of hosts, where their presence is positively correlated with the host's health status. In this study, we assessed the genomes of thirteen representatives of Bifidobacterium breve, which is not onl...

journal_title：BMC genomics

authors： Bottacini F,O'Connell Motherway M,Kuczynski J,O'Connell KJ,Serafini F,Duranti S,Milani C,Turroni F,Lugli GA,Zomer A,Zhurina D,Riedel C,Ventura M,van Sinderen D

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Despite its primary economic importance, genomic information on olive tree is still lacking. 454 pyrosequencing was used to enrich the very few sequence data currently available for the Olea europaea species and to identify genes involved in expression of fruit quality traits. RESULTS:Fruits of Coratina, a ...

journal_title：BMC genomics

authors： Alagna F,D'Agostino N,Torchia L,Servili M,Rao R,Pietrella M,Giuliano G,Chiusano ML,Baldoni L,Perrotta G

更新日期：2009-08-26 00:00:00

abstract：BACKGROUND:Homology-based comparisons of the genes involved in innate immunity across many insect taxa with fully sequenced genomes has revealed a striking pattern of gene gain and loss, particularly among genes that encode proteins involved in clearing pathogens (effectors). However, limited functional annotation in n...

journal_title：BMC genomics

authors： Sackton TB,Clark AG

更新日期：2009-06-07 00:00:00

abstract：BACKGROUND:In natural environments, bacteria must frequently cope with extremely scarce nutrients. Most studies focus on bacterial growth in nutrient replete conditions, while less is known about the stationary phase. Here, we are interested in global gene expression throughout all growth phases, including the adjustme...

journal_title：BMC genomics

authors： Bathke J,Konzer A,Remes B,McIntosh M,Klug G

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not been explored. RESULTS:To investigate the occurrence of DNA methylation changes in LTP, we undertook ...

journal_title：BMC genomics

authors： Maag JL,Kaczorowski DC,Panja D,Peters TJ,Bramham CR,Wibrand K,Dinger ME

更新日期：2017-03-23 00:00:00