Abstract:
:The synergy and shared co-morbidity, certainly interplay between kidney and cardiovascular disease, where advanced renal failure influences on progression of cardiac disease in bi-direction relationship. Cardiovascular diseases are cause of death in almost 50% of uremic patients. Correction of uremia after successful renal transplantation leads to improved cardiovascular status in the majority of kidney transplanted patients. The aim of this study was an evaluation of the influence of renal allograft function on left ventricular remodelling in the first year after transplantation comparing echocardiographic findings before and twelve months after transplantation had been done. In retrospective-prospective study we followed up 30 patients with renal allograft in the first post transplant year. During the study values of serum creatinine and creatinine clearance were monthly monitored. Echocardiographic examination was done before transplantation and one year after the kidney transplantation. Results of our study showed that before transplantation 67% of patients had echocardiographic signs of left ventricular (LV) hypertrophy, while 33% of patients had normal echocardiographic findings. After first post transplant year, 63% of patients showed normal view of LV, and 37% remained with LV hypertrophy. Diastolic dysfunction of LV till the end of study had been reduced from 70% to 40% of patients. The positive echocardiographic remodelling of LV significantly correlated with the rise in creatinine clearance and with the reduction of the serum creatinine. These results confirm positive correlation between renal allograft functional status and remodelling of left ventricular hypertrophy after successful renal transplantation.
journal_name
Bosn J Basic Med Scijournal_title
Bosnian journal of basic medical sciencesauthors
Dzemidzić J,Rasić S,Saracević Adoi
10.17305/bjbms.2009.2827subject
Has Abstractpub_date
2009-05-01 00:00:00pages
102-6issue
2eissn
1512-8601issn
1840-4812journal_volume
9pub_type
杂志文章abstract::Cultural differences in body dissatisfaction, the relationship of stress to body dissatisfaction and individual and cultural body ideals were investigated. Forty-eight United States women and 48 Bosnian women completed the Body Shape Questionnaire (BSQ), the Impact of Event Scale (IES), and a Body Figure Rating Scale....
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2005.3332
更新日期:2005-02-01 00:00:00
abstract::Standard molecular techniques, with only a slight modification, are very useful in obtaining and interpreting the final results in the field of forensic genetic. Data obtained through such analysis are highly reliable and can be used as a very powerful tool that produces valuable results. However, success and swiftnes...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2006.3179
更新日期:2006-05-01 00:00:00
abstract::Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen pretreatment in rats with experimental sciatic nerve ischemia-reperfusion (I/R) injury. Adult male Sprague Dawley rats were divided into four groups (N = 7 in each group...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2015.521
更新日期:2015-08-26 00:00:00
abstract::Neurological outcome is an important determinant of death in admitted survivors after out-of-hospital cardiac arrest (OHCA). Studies demonstrated several significant pre-hospital predictors of ischemic brain injury (time to resuscitation, time of resuscitation, and cause of OHCA). Our aim was to evaluate the relations...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2020.4623
更新日期:2020-08-03 00:00:00
abstract::The aim of this trial was to examine the efficacy and safety of antihypertensive fixed combination lisinopril plus hydrochlorothiazide (Lopril H, Bosnalijek dd) in the treatment of essential arterial hypertension. In our trial we included 297 patients, aged 54.65+/-9.6 years, with treated or untreated hypertension and...
journal_title:Bosnian journal of basic medical sciences
pub_type: 临床试验,杂志文章,多中心研究
doi:10.17305/bjbms.2007.3031
更新日期:2007-11-01 00:00:00
abstract::Previous studies suggested that oxidative stress is related to the onset and development of osteoporosis. Moreover, it was demonstrated that berberine has a protective effect against oxidative stress-induced injuries. In this study, we aimed to investigate the effect and mechanism of action of berberine on rats with i...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2017.2596
更新日期:2017-11-20 00:00:00
abstract::The aim of the study was to verify the presence of mutated tumor suppresser gene p53 in intestinal mucosa with histologically confirmed premalignant lesions and gastric carcinoma, and assess its prognostic value. The paper presents prospective study that included 50 patients with gastric adeno-carcinoma of intestinal ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2007.3080
更新日期:2007-02-01 00:00:00
abstract::Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Mature epithelial tissues originate from different embryonic germ layers. The objective of this research was to explore the presence and localization of TFF3 peptide in mouse embryonic epithelia and...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2017.1838
更新日期:2017-08-20 00:00:00
abstract::Status epilepticus (SE) is defined as continuous seizure activity lasting more than 5 minutes. It results in neuronal cell death, mediated by endoplasmic reticulum (ER) stress response. Previously, metformin demonstrated neuroprotective effects in primary cortical neurons. In this study, we analyzed the effect of metf...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2017.2044
更新日期:2018-02-20 00:00:00
abstract:BACKGROUND AND PURPOSE:Clinical research of drugs is a researching step subsequent to the preclinical studies in experimental animals. The aim of our research was to evaluate animal model of wound healing process after the burn inducement and effects of the ointment containing natural plants on the process of burn heal...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2003.3495
更新日期:2003-11-01 00:00:00
abstract::Spermatogenesis is a tightly controlled, multi-step process in which mature spermatozoa are produced. Disruption of regulatory mechanisms in spermatogenesis can lead to male infertility, various diseases of male reproductive system, or even cancer. The spermatogenic impairment in infertile men can be associated with d...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,评审
doi:10.17305/bjbms.2018.3477
更新日期:2019-02-12 00:00:00
abstract::Diabetes mellitus can be looked upon as an array of diseases, all of which exhibit common symptoms. While pathogenesis of IDDM (insulin dependant diabetes mellitus) is well understood, the same is not true for diabetes mellitus type II. In the latter case, relative contribution of the two factors (insulin resistance o...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2006.3135
更新日期:2006-08-01 00:00:00
abstract::Dermatofibrosarcoma protuberans (DFSP) is an uncommon soft tissue sarcoma that originates from the dermis or subcutaneous tissue in the skin. While its prognosis is generally favorable, disease recurrence is relatively frequent. Because morbidity after repeated surgery may be significant, an optimized prediction of re...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2020.5088
更新日期:2020-10-20 00:00:00
abstract::Tocotrienol rich fraction (TRF) is an extract of palm oil, which consists of 25% alpha tocopherol (α-TCP) and 75% tocotrienols. TRF has been shown to possess potent antioxidant, anti-inflammatory, anticancer, neuroprotection, and cholesterol lowering activities. Glutamate is the main excitatory amino acid neurotransmi...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2014.4.91
更新日期:2014-11-16 00:00:00
abstract::Large scale genetic association meta-analyses showed that neurocan (NCAN) gene polymorphism rs1064395 is susceptibility locus for bipolar disorder. These studies also included patients with bipolar disorder originated from Bosnia and Herzegovina. Followed by theory of shared genetic elements between bipolar disorder a...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2012.2446
更新日期:2012-11-01 00:00:00
abstract::Obese patients with type 2 diabetes and impaired glucose tolerance are at increased risk of development of cardiovascular diseases. Endothelial dysfunction may be a reason for development of atherosclerosis and cardiovascular diseases. Lifestyle modification, increased physical activity, weight reduction, energy restr...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2008.2882
更新日期:2008-11-01 00:00:00
abstract::Non-small-cell lung cancer (NSCLC) with KRAS (Kirsten RAt Sarcoma 2 viral oncogene homolog) mutation has become a clinical challenge in cancer treatment as KRAS-mutant tumors are often resistant to conventional anti-tumor therapies. Activated CDC42-associated kinase 1 (ACK1), an activator of protein kinase B (AKT), is...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2020.4746
更新日期:2020-06-01 00:00:00
abstract::The glutathione S-transferase (GST) genes encode enzymes that mediate the detoxification of xenobiotics by catalyzing the conjugation of glutathione (GSH) to xenobiotic substrates. The aim of the current study is to investigate the association between GSTT1 and GSTM1 polymorphisms and chronic myeloid leukemia (CML) am...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2019.4176
更新日期:2019-04-15 00:00:00
abstract::We investigated serum concentration of C-reactive protein (CRP) and measures of adiposity in 30 patients with type 2 diabetes mellitus (15 male, 15 female) and 30 age and sex-matched apparently healthy subjects. CRP concentration was determined by laser nephelometry (BN II Analyzer) and CardioPhase high-sensitivity CR...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2007.3021
更新日期:2007-11-01 00:00:00
abstract::The medicinal significance of Ephedra is based on the sympathomimetic properties of ephedrine (E) alkaloids. Pharmacological effects depend on the phytocomposition of individual Ephedra species. The aim of this study was to measure the total alkaloids content (TAC), total phenolics content (TPC), and total flavonoids ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2015.539
更新日期:2015-07-18 00:00:00
abstract::Recent literature suggests that alterations in both neural and structural components of the neuromuscular system are major determinants of knee extensor muscle weakness after total knee arthroplasty (TKA). Therefore, the goal of this study was to investigate the maximal voluntary strength (MVS), voluntary muscle activ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,meta分析
doi:10.17305/bjbms.2019.3814
更新日期:2020-02-05 00:00:00
abstract::Long non-coding RNAs (lncRNAs) are involved in a range of biological processes, such as cellular differentiation, migration, apoptosis, invasion, proliferation, and transcriptional regulation. The aberrant expression of lncRNAs plays a significant role in several cancer types. Aurora kinases are increasingly expressed...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2019.4155
更新日期:2020-02-05 00:00:00
abstract::Growth hormone is essential for body growth but it also modulates metabolic pathways as well as neural, reproductive, immune, cardiovascular, and pulmonary functions. Numerous beneficial effects of growth hormone have led to its expanded therapeutic use in both children and adults. There are several officially approve...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,评审
doi:10.17305/bjbms.2004.3365
更新日期:2004-10-01 00:00:00
abstract::The nonparasitic primary splenic cysts are very rare clinical entity. In the past, splenectomy was the treatment of choice but with the recognition of the spleen's important immunological function, spleen-preserving surgery is the preferred treatment modality. We hereby present a case of a large splenic mesothelial cy...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,评审
doi:10.17305/bjbms.2013.2395
更新日期:2013-05-01 00:00:00
abstract::Kidney transplantation (Ktx) is generally performed during end stage renal disease due to a loss of the kidneys' ability to filter wastes from the circulatory system. Acute graft-versus-host disease (GVHD) after Ktx is a life-threatening complication that progresses to organ failure, systemic complications, and death....
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2011.2594
更新日期:2011-05-01 00:00:00
abstract::Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common condition; when conservative approaches are not effective, surgical techniques aimed at reducing the airway obstruction effect are used. This retrospective study aimed at comparing the functional outcomes in patients with OSAHS undergoing uvulopalatopharyng...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2020.4724
更新日期:2020-04-27 00:00:00
abstract::Having in mind the fact that cerebrovascular disease (CVB) takes today in medicine, in spite of diagnostic and therapeutic modernisation, the third place of mortality causes in the world (behind cordial and malignant diseases, but in front of depressions), and the second place of invalidity cause (right after trauma) ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2002.3585
更新日期:2002-12-01 00:00:00
abstract::Evidence gained from animals and humans suggests that the encephalic opioid system might be involved in the development of drug addiction through its role in reward. Our aim is to assess the influence of genetic variations in the opioid receptor mu 1 on alcohol and tobacco consumption in a Spanish population. 763 unre...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2015.243
更新日期:2015-04-25 00:00:00
abstract::Staphylococcus aureus has long been recognized as one of the leading cause of hospital infections all over the world. Increased frequency of methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients and possibility of vancomycin resistance requires rapid and reliable characterization of isolates and ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2008.2930
更新日期:2008-08-01 00:00:00
abstract::The research has included 422 patients aged between 25 to 60, of whom 341 were men and 81 women. The purpose of research was to determine impact of diet and physical activity in the treatment of metabolic syndrome during the six month period. Processing of results through descriptive and discriminative analysis have i...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2010.2718
更新日期:2010-05-01 00:00:00