Abstract:
OBJECTIVE:The growth of solid tumors requires angiogenesis. Evidence indicates that mast cells (MCs) play an important role in tumor angiogenesis but results are not definitive. The aim of this study is to investigate the possible effects of angiogenesis and the presence of MCs on the prognosis of renal cell carcinoma (RCC). PATIENTS AND METHODS:The study involved 40 patients with RCC (24 men and 16 women who were treated with radical nephrectomy between 1995 and 2006, at our institution. The routine mast cell tryptase staining method was used to assess the MCs in both normal tissue and tumoral tissue. The immunohistochemical staining for CD34 antigen was used for determination of microvessel density. The relation between MC count and tumor status such as tumor stage, size, grade, and other clinicopathologic parameters in RCC were evaluated in this study. RESULTS:We found no relationship between the number of MCs and patient age, sex, tumor stage, grade, size. No association was noted between angiogenesis and either patient sex or age, tumor size, stage, and grade. No statistically significant correlation was found between the number of MCs and microvessel density in RCC (P-value = 0.45) but the max value of MCs and MVD were in clear cell carcinoma. CONCLUSIONS:The MC count was not associated with tumor status such as tumor stage, size, grade, and other clinicopathologic parameters, however, MCs may be related to tumor angiogenesis and acceleration of tumor growth in RCC and therefore need further evaluation in RCC.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Mohseni MG,Mohammadi A,Heshmat AS,Kosari F,Meysamie APdoi
10.1007/s11255-009-9577-2subject
Has Abstractpub_date
2010-03-01 00:00:00pages
109-12issue
1eissn
0301-1623issn
1573-2584journal_volume
42pub_type
杂志文章abstract:BACKGROUND:Paediatric kidney transplantation has different aspects in adults in terms of underlying primary renal disease, surgical technique, perioperative care and graft prognosis. Significant urological problems are present in a high percentage of paediatric recipients. This study was undertaken to characterize paed...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550558
更新日期:1998-01-01 00:00:00
abstract::Among 104 patients with urethral strictures treated over a period of 3 years, sixty-five (63%) had complications such as inflammatory periurethral mass, watering-can perineum with discharging sinuses and fistulas, associated urethral calculi, periurethral abscesses and urethral diverticula. Seventy-four per cent of th...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549587
更新日期:1989-01-01 00:00:00
abstract::Cyclophosphamide was introduced in 1958 in an effort to minimize the side effects of nitrogen mustard. Cyclophosphamide (Cytoxan, Endoxan) is not an alkylating agent which has been used for the treatment of a variety of non-malignant as well as malignant diseases. It has also recently been the focus of considerable in...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082484
更新日期:1985-01-01 00:00:00
abstract::Hemangiopericytoma (HPC) arising from within the urinary bladder is exceptionally rare. A 45-year-old man having the symptoms of left groin pain, vague suprapubic discomfort and frequency was admitted to our clinic. Pelvic tomography revealed a tumor in the bladder wall measuring 4 x 3 cm and was not clearly distinct ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6673-4
更新日期:2006-01-01 00:00:00
abstract::We report the unusual case of a patient with G3 pT1 transitional cell carcinoma (TCC) of the bladder, which was treated with repeated transurethral resection and maintenance intravesical Bacillus Calmette-Guérin (BCG) therapy. At 30 months follow-up, a symptomatic, solitary iliac lymph node mass was identified and bio...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9187-9
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To perform a systematic review and meta-analysis to evaluate the cardiovascular prevention effect of aspirin among patients with chronic kidney disease (CKD). METHODS:A comprehensive literature search was conducted in Embase, PubMed, and Cochrane library (up to March 2019) without language limitations. Randomi...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析
doi:10.1007/s11255-019-02350-8
更新日期:2020-02-01 00:00:00
abstract::Multiloculated renal cell carcinoma and multilocular renal cyst with renal cell carcinoma are uncommon diseases. We report on 2 cases of multiloculated renal cell carcinoma. To our knowledge 16 cases of multiloculated renal cell carcinoma and multilocular renal cyst with renal cell carcinoma have been previously descr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02583984
更新日期:1991-01-01 00:00:00
abstract::Sex cord stromal tumors are rare and account for approximately 6% of all testicular neoplasms. We report a case of sex cord tumor composed of granulosa cells and Sertoli cells in the adult testis. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000022907.66796.61
更新日期:2003-01-01 00:00:00
abstract::Varicocele, the leading cause of male infertility, can impair sperm quality and fertility via various oxidative stress mechanisms. An imbalance between excessive reactive oxygen species production and antioxidant protection causes alterations in nuclear and mitochondrial sperm DNA, thus rendering a subset of varicocel...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-018-1839-4
更新日期:2018-04-01 00:00:00
abstract::This prospective study was undertaken to study the spectrum of renal failure and the outcome in elderly patients. Patients included in the study group were elderly (age>60 years) who either attended outpatient renal clinic and or were hospitalized. Renal failure was classified as acute renal failure (ARF), rapidly pro...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-0089-z
更新日期:2006-01-01 00:00:00
abstract::This is the first prospective study to investigate the association between kidney stones, bone mineral density, serum testosterone, colon cancer and O. formigenes colonization. 40 kidney stone patients and 85 controls were enrolled. O. formigenes colonization was established. BMD was examined from T- and Z-scores usin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02627-3
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION:Erectile dysfunction (ED) is one of the most encountered male health problem and sildenafil citrate is used worldwide for treatment of ED. Aim of the present study was to determine and evaluate hemodynamic effects of sildenafil citrate on segmental branches of bilateral renal arteries of cases with ED. PA...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-3621-7
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To evaluate the association of shock-wave lithotripsy (SWL) for kidney stones and hypertension or diabetes. METHODS:Patients with urolithiasis treated by SWL were retrospectively identified. To assess whether shock-wave application to the kidney is associated with long-term adverse effects, patients after SWL ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-018-1857-2
更新日期:2018-07-01 00:00:00
abstract::We report a 49-year-old woman with exstrophy of the bladder. Our living case constitutes a rare example of bladder exstrophy cases, who lived about 50 years without any severe complication or intervention. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550721
更新日期:1996-01-01 00:00:00
abstract::The follow-up study has been performed in 4 male patients with nephrogenic diabetes insipidus lasting for 4 to 15 years. Hydronephrosis or hydroureter appeared to be caused by polyuria with or without urinary tract obstruction. The efficacy of drainage operation is emphasized when polyuria surpasses the transporting a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549772
更新日期:1990-01-01 00:00:00
abstract::In 68 men with benign prostatic hyperplasia, we evaluated the association between obesity and prostatic enlargement, as well as changes in serum levels of oestradiol, testosterone, dihydroepiandrosterone and dihydroepiandrosterone sulphate. Despite the larger adenomas, no increase in the symptom score for BPH was obse...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550138
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:We describe a new technique that can easily be used as a tension-free practical alternative in closing the renal defects resulting after open partial nephrectomy (PN). METHODS:A new technique (called "lipocorticoplasty") where "wrapped fatty tissue" was placed in the tumor crater to close the renal defects t...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9899-8
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:Frailty is a multicausal syndrome characterized by a decrease in strength, resistance and physiological function, which makes the individual vulnerable and dependent, and increases his/her mortality. This syndrome is more prevalent among older individuals, and chronic kidney disease patients, particularly ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02757-8
更新日期:2021-01-30 00:00:00
abstract::Serum concentrations of luteinizing hormone (LH), testosterone, prostatic acid phosphatase (PAP) and prostatic specific antigen (PSA) were measured in 16 patients with advanced prostatic cancer before and after treatment with luteinizing hormone-releasing hormone (LHRH) analogue. An initial rise of serum LH and testos...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564863
更新日期:1998-01-01 00:00:00
abstract:AIM:Skin test anergy is common in patients with uremia and during maintenance hemodialysis treatment. However, up to date only one study concerning skin test in peritoneal dialysis patients has focused on the issue. Our cross-sectional controlled study was conducted to analyze the correlation of purified protein deriva...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02467-1
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:We reviewed our experience with ureteral complications and secondary ureteral implantation after kidney transplantation. METHODS:Between 1997 and 2005, 636 patients underwent kidney transplantation at our transplant center. Ureteral implantation was performed in the Lich-Gregoire technique. Thirty-one patie...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9893-6
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Smoking habit is the major risk factor for bladder cancer (BC), related to about 50% of these tumors; however, the tobacco dose-effect impact on BC immune treatment is underexplored. This study evaluates the impact of smoke load on non-muscle invasive bladder cancer (NMIBC) prognosis after intravesical BCG. ME...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02438-6
更新日期:2020-08-01 00:00:00
abstract::Relying on their own observations, the authors describe nine patients in whom Fraley's syndrome was diagnosed and treated operatively. In six of them, calycopyeloneostomy was performed. In three of the patients, because of complications, the upper pole of the kidney was excised together with the changed calyx. In nonc...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082129
更新日期:1978-01-01 00:00:00
abstract:PURPOSE:To evaluate the role of microvessel density (MVD) in predicting lymph node (LN) metastasis in penile squamous cell carcinoma (PSCC). MATERIALS AND METHODS:Records of 266 patients with PSCC were analyzed. Parameters examined were tumor stage, grade, nodal status, intratumoral and peritumoral MVD. Univariate and...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1565-3
更新日期:2017-06-01 00:00:00
abstract::The aim of the present study was to examine subpreputial bacteriology and to compare it with the urine cultures of healthy male children. Seventy-two male children were divided into two groups as A and B according to age. In both groups preputial sac and urine cultures were taken simultaneously. Gram (+) enteric cocci...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007120520884
更新日期:2000-01-01 00:00:00
abstract::Cyproterone acetate was given as monotherapy to 18 patients with advanced prostatic carcinoma at a weekly dose of 300 mg. Progression was observed in all of the patients; median time to progression was 35 months and median survival time was 48 months. Partial response, stabilization, progression and exitus rates by ye...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551344
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Uremic pruritus (UP) is a highly prevalent and disturbing problem in patients with advanced chronic kidney disease (CKD); however, treatment of UP is largely unsatisfactory. The present study was designed to investigate the effectiveness of mirtazapine, an atypical antidepressant agent with potent antagonist...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02473-3
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To survey long-term outcomes of dialysis patients with urothelial cancers who have undergone complete urinary tract exenteration (bilateral nephroureterectomy and cystectomy). METHODS:We retrospectively reviewed our patients with urinary tract urothelial cancer. Forty-two dialysis patients who underwent comple...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1522-1
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:Estimated glomerular filtration rate (GFR) is a useful tool for the detection of chronic kidney disease (CKD). Several methods have been proposed, but findings can vary in specific groups such as patients with diabetes, elderly and high and low body mass index and, also, with the stage of CKD. The objective of ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0607-8
更新日期:2014-06-01 00:00:00
abstract::Five cases of spontaneous rupture of the renal parenchyma are reported. Two patients had renal cell cancer, one sustained acute purulent pyelonephritis secondary to stone related ureteral obstruction, one suffered from aposthematous pyelonephritis without obstruction, while one had chronic pyelonephritis and a cortica...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768275
更新日期:1994-01-01 00:00:00