Rheumatic manifestations of renal disease.

abstract：PURPOSE OF REVIEW:Infections have been suggested to contribute to disease induction and reactivation in many of the idiopathic vasculitides. This review describes and evaluates the evidence that microbes are involved in the etiopathogenesis of these diseases. RECENT FINDINGS:Large-vessel vasculitis has recently been a...

journal_title：Current opinion in rheumatology

authors： van Timmeren MM,Heeringa P,Kallenberg CG

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Individuals with systemic lupus erythematosus (SLE) have an increased susceptibility to certain types of cancer. Given concerns focused on this issue, we present a review of this important topic. RECENT FINDINGS:In non-Hodgkin lymphoma (NHL), a several-fold increased risk is seen in SLE versus the ge...

journal_title：Current opinion in rheumatology

authors： Bernatsky S,Kale M,Ramsey-Goldman R,Gordon C,Clarke AE

更新日期：2012-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Takayasu arteritis remains a therapeutic challenge. In spite of current treatments, progression of vascular lesions is observed frequently. The purpose of this article is to describe advances in therapeutic strategies for Takayasu arteritis. RECENT FINDINGS:Immunosuppressive agents including methotre...

journal_title：Current opinion in rheumatology

authors： Liang P,Hoffman GS

更新日期：2005-01-01 00:00:00

abstract：:Idiopathic inflammatory myositis in children includes multiple disease entities, but is primarily made up of juvenile dermatomyositis and, to a lesser degree, juvenile polymyositis. Much new information has been published in the last few years about these diseases, including the epidemiology, pathogenesis, clinical di...

journal_title：Current opinion in rheumatology

authors： Reed AM

更新日期：2001-09-01 00:00:00

abstract：:Tumor necrosis factor-alpha, acting through its receptors expressed on all cells of the body, is a key mediator of inflammation and immunity. However, its overproduction may also lead to pathologic changes. The latter situation occurs often in chronic inflammatory diseases such as rheumatoid arthritis. The concept sug...

journal_title：Current opinion in rheumatology

authors： Ziolkowska M,Maslinski W

更新日期：2003-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article was to review the recent contributions to the scoring methods of PET in vasculitis as well as to its role in the diagnostic work-up. RECENT FINDINGS:Both visual and semiquantitative scoring methods can be used to interpret PET scans. PET has been shown to be both sensitive and...

journal_title：Current opinion in rheumatology

authors： Pipitone NAM,Versari A,Salvarani C

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In contrast to the disease remission enjoyed by a majority of rheumatoid arthritis (RA) patients during pregnancy, the immediate postpartum period is generally characterized by flare. Managing symptoms during this time is challenging because the potential transfer of medication into the breast milk of...

journal_title：Current opinion in rheumatology

authors： Sammaritano LR,Bermas BL

更新日期：2014-05-01 00:00:00

abstract：:Interstitial lung disease frequently complicates rheumatic disorders, especially polymyositis-dermatomyositis, rheumatoid arthritis, systemic sclerosis, and mixed connective tissue disease. In this article, we review the current data supporting the use of azathioprine, cyclophosphamide, chlorambucil, cyclosporine, and...

journal_title：Current opinion in rheumatology

authors： McCune WJ,Vallance DK,Lynch JP 3rd

更新日期：1994-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review developments in the literature concerning work disability in the rheumatic diseases. RECENT FINDINGS:There have been three sets of studies to emerge in the last year. In the first, several studies analyze alternative research methods to document work disability. The second set uses qualitat...

journal_title：Current opinion in rheumatology

authors： Yelin E

更新日期：2007-03-01 00:00:00

abstract：:Refinement of criteria for classifying childhood rheumatic diseases has contributed to earlier, more complete, and more precise diagnosis of children with spondyloarthropathies. Recent additions to the literature have contributed new international perspectives relating to the prevalence of juvenile spondyloarthropathi...

journal_title：Current opinion in rheumatology

authors： Rosenberg AM

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF THE REVIEW:To define gout conditions and hyperuricemia. RECENT FINDINGS:Gout is defined as an arthritic condition resulting from the deposition of monosodium urate (MSU) crystals in and/or around joints, following long-standing hyperuricemia. Several recent ultrasound studies disclosed MSU deposits in a lar...

journal_title：Current opinion in rheumatology

authors： Bardin T,Richette P

更新日期：2014-03-01 00:00:00

abstract：:Eosinophilic infiltration into skeletal muscle, although rare, has been described in a diverse group of conditions. It most commonly occurs in parasitic infection as focal eosinophilic myositis but can be a feature of systemic hypereosinophilic conditions such as eosinophilia-myalgia syndrome and idiopathic hypereosin...

journal_title：Current opinion in rheumatology

authors： Pickering MC,Walport MJ

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To present an updated summary of the relationship between joint shape and the development of osteoarthritis, with a particular focus on osteoarthritis of the hip. RECENT FINDINGS:Osteoarthritis of the hip is highly heritable, with a genetic contribution estimated at 60%. Among the genes that have bee...

journal_title：Current opinion in rheumatology

authors： Baker-LePain JC,Lane NE

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:It is an understatement to say that drug approvals in systemic lupus erythematosus (SLE), lupus nephritis, and Sjogren's syndrome have lagged far behind those in other autoimmune diseases, such as rheumatoid arthritis and psoriatic arthritis. Reasons for this are multiple and include the molecular and...

journal_title：Current opinion in rheumatology

authors： Narain S,Berman N,Furie R

更新日期：2020-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights the present state of efforts at registry implementation which exist internationally. These efforts are contrasted with those in the USA. RECENT FINDINGS:The implications of the different data which are derived from diverse registry sources are discussed. The need for long-term ...

journal_title：Current opinion in rheumatology

authors： Kremer JM,Gibofsky A,Greenberg JD

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease characterized by IgG-autoantibodies to nuclear antigens that can deposit in the kidney and trigger lupus nephritis. Neutrophils accumulate in the kidneys of patients with proliferative LUPUS NEPHRITIS and neutrophil products and a s...

journal_title：Current opinion in rheumatology

authors： Nishi H,Mayadas TN

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Microscopic polyangiitis is defined within the context of primary systemic vasculitis. The presentation and management of renal involvement in microscopic polyangiitis is discussed, with emphasis on prognosis and outcomes. Potential roles of newer therapies are reviewed. RECENT FINDINGS:The histologi...

journal_title：Current opinion in rheumatology

authors： Jayne D

更新日期：2008-01-01 00:00:00

abstract：:There is growing evidence that distinct molecular and cellular interactions in the rheumatoid synovium result in a complex cascade of pathophysiologic events. These interactions finally lead to progressive joint destruction, in a way that is different from all other joint diseases. Keystones are inflammation, prolifer...

journal_title：Current opinion in rheumatology

authors： Müller-Ladner U

更新日期：1996-05-01 00:00:00

abstract：:This article reviews recent publications related to the classification and treatment of juvenile spondyloarthropathies. We have included studies on adult onset spondyloarthropathies that are particularly relevant to childhood onset disease. Significant questions concerning classification of juvenile spondyloarthropath...

journal_title：Current opinion in rheumatology

authors： Bukulmez H,Colbert RA

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on proteinase 3 (PR3), the preferred target of antineutrophil cytoplasmic antibodies (ANCAs) in Wegener's granulomatosis. Deciphering the molecular associations that PR3 can make with its cognate partners might help to understand its pathophysiological significance in Wegener's gra...

journal_title：Current opinion in rheumatology

authors： Witko-Sarsat V,Reuter N,Mouthon L

更新日期：2010-01-01 00:00:00

abstract：:With the opportunity for long-term follow-up, it has been appreciated that disease severity may vary considerably in patients with Wegener's granulomatosis, polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome. Although combined therapy with cyclophosphamide and glucocorticoids continues to be th...

journal_title：Current opinion in rheumatology

authors： Langford CA,Sneller MC

更新日期：1997-01-01 00:00:00

abstract：:The spondyloarthropathies are diseases influenced by genetic predisposition and, to a varying extent, infectious triggers. A causal role for bacterial infections is most clear for reactive arthritis. Recent insights into arthritogenic components of bacteria may set the stage for a better understanding of disease patho...

journal_title：Current opinion in rheumatology

authors： Pacheco-Tena C,Zhang X,Stone M,Burgos-Vargas R,Inman RD

更新日期：2002-07-01 00:00:00

abstract：:Psoriatic arthritis is an inflammatory arthropathy associated with psoriasis and is classified as a seronegative spondyloarthropathy. It occurs in approximately 5% to 7% of patients with psoriasis. The etiopathogenesis of psoriatic arthritis is not well known, but interaction among genetic, immunologic, and environmen...

journal_title：Current opinion in rheumatology

authors： Espinoza LR,Cuéllar ML,Silveira LH

更新日期：1992-08-01 00:00:00

abstract：:Osteoporosis occurs in patients with rheumatoid arthritis, acromegaly, anorexia nervosa, chronic liver disease, sickle cell hemoglobinopathies, and mastocytosis. Osteomalacia occurs in patients with renal tubular acidosis, and with tumors. ...

journal_title：Current opinion in rheumatology

authors： Cormier C

更新日期：1991-06-01 00:00:00

abstract：:During the past 2 years, four papers describing new research studies and three papers reviewing the literature were published. These seven papers address longstanding issues, including 1) the presence or absence of cognitive impairment in systemic lupus erythematosus (SLE), 2) the prevalence of such impairment within ...

journal_title：Current opinion in rheumatology

authors： Bleiberg J,Bunning R

更新日期：1998-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Rapid introduction of newly developed drugs in the absence of clear understanding of the pathophysiologic mechanisms behind drug-induced lupus erythematosus (DILE) can sometimes make DILE difficult to recognize in clinical practice. The purpose of this review is to summarize drugs most recently report...

journal_title：Current opinion in rheumatology

authors： He Y,Sawalha AH

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review the evidence and recent developments leading to novel therapeutics in scleroderma. RECENT FINDINGS:Recent advances have been made in understanding the key pathogenetic aspects of scleroderma, and these have led to potential targeted therapeutic agents for the ma...

journal_title：Current opinion in rheumatology

authors： Ong VH,Denton CP

更新日期：2010-05-01 00:00:00

abstract：:Neoplasia can be associated with a wide range of rheumatologic manifestations. Literature over the last 12 months has reviewed metastasis of solid tumors to the joint and hypertrophic pulmonary osteoarthropathy. Vasculitis has been reported as a paraneoplastic syndrome associated with both hematologic and solid malign...

journal_title：Current opinion in rheumatology

authors： Brooks PM

更新日期：1992-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The hyper-IgD and periodic fever syndrome (HIDS) is one of the classical monogenetic hereditary autoinflammatory disorders, and together with the more severe mevalonic aciduria it is also known as 'mevalonate kinase deficiency' (MKD). In this study, we will give an overview of the primary research on ...

journal_title：Current opinion in rheumatology

authors： Stoffels M,Simon A

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite its critical roles in body movement, structure, and metabolism, skeletal muscle remains underappreciated in the context of rheumatoid arthritis. In rheumatoid arthritis, chronic inflammation, physical inactivity, and medication toxicities impair skeletal muscle. These skeletal muscle alteratio...

journal_title：Current opinion in rheumatology

authors： Andonian BJ,Huffman KM

更新日期：2020-05-01 00:00:00