Characterization of Mce4A protein of Mycobacterium tuberculosis: role in invasion and survival.

abstract：BACKGROUND:Bovicin HC5 is an antimicrobial peptide that shows a broad spectrum of activity and potential for biotechnological and therapeutic applications. To gain insight about the safety of bovicin HC5 application, the histological and immunostimulatory effects of orally administrated bovicin HC5 to BALB/c mice were ...

journal_title：BMC microbiology

authors： Paiva AD,Fernandes KM,Dias RS,Rocha Ados S,Oliveira LL,Neves CA,Paula SO,Mantovani HC

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:Following genital chlamydial infection, an early T helper type 1 (Th1)-associated immune response precedes the activation and recruitment of specific Th1 cells bearing distinct chemokine receptors, subsequently leading to the clearance of Chlamydia. We have shown that CCR5, a receptor for CCL5, is crucial fo...

journal_title：BMC microbiology

authors： Sakthivel SK,Singh UP,Singh S,Taub DD,Igietseme JU,Lillard JW Jr

更新日期：2008-08-13 00:00:00

abstract：BACKGROUND:Clostridium thermocellum is a Gram-positive thermophilic anaerobic bacterium with the unusual capacity to convert cellulosic biomass into ethanol and hydrogen. Identification and characterization of protein complexes in C. thermocellum are important toward understanding its metabolism and physiology. RESULT...

journal_title：BMC microbiology

authors： Peng Y,Luo Y,Yu T,Xu X,Fan K,Zhao Y,Yang K

更新日期：2011-01-26 00:00:00

abstract：BACKGROUND:The environment is the likely source of many pathogenic mycobacterial species but detection of mycobacteria by bacteriological tools is generally difficult and time-consuming. Consequently, several molecular targets based on the sequences of housekeeping genes, non-functional RNA and structural ribosomal RNA...

journal_title：BMC microbiology

authors： Radomski N,Roguet A,Lucas FS,Veyrier FJ,Cambau E,Accrombessi H,Moilleron R,Behr MA,Moulin L

更新日期：2013-12-03 00:00:00

abstract：BACKGROUND:Bacteria adapted to live within animals can protect their hosts against harmful infections. Beyond antagonism with pathogens, a 'defensive' bacterial symbiont could engage in additional interactions with other colonizing micro-organisms. A single bacterium might thus have cascading ecological impacts on the ...

journal_title：BMC microbiology

authors： Dahan D,Preston GM,Sealey J,King KC

更新日期：2020-06-15 00:00:00

abstract：BACKGROUND:Alpha-isopropylmalate synthase (alpha-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding alpha-IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of Tandem Repea...

journal_title：BMC microbiology

authors： Yindeeyoungyeon W,Likitvivatanavong S,Palittapongarnpim P

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in treatment failures of bacterial infections. While this phenomenon has posed a great threat in public health, mechanisms underlying their formation in Staphylococcus aureus remain largely unknown. Increasing evi...

journal_title：BMC microbiology

authors： Sahukhal GS,Pandey S,Elasri MO

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:Generation of extended- spectrum β- lactamases is one of the major mechanisms by which clinical Klebsiella pneumoniae develop resistance to antibiotics. Combined antibiotics prove to be a relatively effective method of controlling such resistant strains. Some of Chinese herbal active ingredients are known to...

journal_title：BMC microbiology

authors： Cai W,Fu Y,Zhang W,Chen X,Zhao J,Song W,Li Y,Huang Y,Wu Z,Sun R,Dong C,Zhang F

更新日期：2016-08-08 00:00:00

abstract：BACKGROUND:The global spread of bacterial resistance has given rise to a growing interest in new anti-bacterial agents with a new strategy of action. Pilicides are derivatives of ring-fused 2-pyridones which block the formation of the pili/fimbriae crucial to bacterial pathogenesis. They impair by means of a chaperone-...

journal_title：BMC microbiology

authors： Piatek R,Zalewska-Piatek B,Dzierzbicka K,Makowiec S,Pilipczuk J,Szemiako K,Cyranka-Czaja A,Wojciechowski M

更新日期：2013-06-12 00:00:00

abstract：BACKGROUND:The KdpD/KdpE two-component system of Escherichia coli regulates expression of the kdpFABC operon encoding the high affinity K+ transport system KdpFABC. The input domain of KdpD comprises a domain that belongs to the family of universal stress proteins (Usp). It has been previously demonstrated that UspC bi...

journal_title：BMC microbiology

authors： Heermann R,Lippert ML,Jung K

更新日期：2009-07-09 00:00:00

abstract：BACKGROUND:The Uzon Caldera is one of the places on our planet with unique geological, ecological, and microbiological characteristics. Uzon oil is the youngest on Earth. Uzon oil has unique composition, with low proportion of heavy fractions and relatively high content of saturated hydrocarbons. Microbial communities ...

journal_title：BMC microbiology

authors： Peltek SE,Bryanskaya AV,Uvarova YE,Rozanov AS,Ivanisenko TV,Ivanisenko VA,Lazareva EV,Saik OV,Efimov VM,Zhmodik SM,Taran OP,Slynko NM,Shekhovtsov SV,Parmon VN,Dobretsov NL,Kolchanov NA

更新日期：2020-11-24 00:00:00

abstract：BACKGROUND:Burkholderia pseudomallei is the etiological agent of melioidosis and a CDC category B select agent with no available effective vaccine. Previous immunizations in mice have utilized the lipopolysaccharide (LPS) as a potential vaccine target because it is known as one of the most important antigenic epitopes ...

journal_title：BMC microbiology

authors： Stone JK,Mayo M,Grasso SA,Ginther JL,Warrington SD,Allender CJ,Doyle A,Georgia S,Kaestli M,Broomall SM,Karavis MA,Insalaco JM,Hubbard KS,McNew LA,Gibbons HS,Currie BJ,Keim P,Tuanyok A

更新日期：2012-11-05 00:00:00

abstract：BACKGROUND:Chlortetracycline (CTC) is one of the commercially important tetracyclines (TCs) family product and is mainly produced by Streptomyces. CTC is still in a great demand due to its broad-spectrum activity against pathogens. Engineering transcriptional control allows the cell to allocate its valuable resources t...

journal_title：BMC microbiology

authors： Kong L,Liu J,Zheng X,Deng Z,You D

更新日期：2019-12-10 00:00:00

abstract：BACKGROUND:Establishing an optimal proportion of nitrifying microbial populations, including ammonia-oxidizing bacteria (AOB), nitrite-oxidizing bacteria (NOB), complete nitrite oxidizers (comammox) and ammonia-oxidizing archaea (AOA), is important for ensuring the efficiency of nitrification in water treatment systems...

journal_title：BMC microbiology

authors： Scarascia G,Cheng H,Harb M,Hong PY

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:The increasing availability of whole genome sequences allows the gene or protein content of different organisms to be compared, leading to burgeoning interest in the relatively new subfield of pan-genomics. However, while several studies have analyzed protein content relationships in specific groups of bacte...

journal_title：BMC microbiology

authors： Trost B,Haakensen M,Pittet V,Ziola B,Kusalik A

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:Quorum sensing is a communication system that regulates gene expression in response to population density and often regulates virulence determinants. Deletion of the luxR homologue vjbR highly attenuates intracellular survival of Brucella melitensis and has been interpreted to be an indication of a role for ...

journal_title：BMC microbiology

authors： Weeks JN,Galindo CL,Drake KL,Adams GL,Garner HR,Ficht TA

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Meiotic cells undergo two rounds of nuclear division and generate gametes. Previous studies have indicated that a number of transcription factors modulate the transcriptome in successive waves during meiosis and spore formation in fission yeast. However, the mechanisms underlying the post-transcriptional reg...

journal_title：BMC microbiology

authors： Togashi N,Yamashita A,Sato M,Yamamoto M

更新日期：2014-07-15 00:00:00

abstract：BACKGROUND:We and others have previously shown that alterations in the mammalian gut microbiome are associated with diet, notably early life exposure to a maternal high fat diet (HFD). Here, we aimed to further these studies by examining alterations in the gut microbiome of juvenile Japanese macaques (Macaca fuscata) t...

journal_title：BMC microbiology

authors： Pace RM,Prince AL,Ma J,Belfort BDW,Harvey AS,Hu M,Baquero K,Blundell P,Takahashi D,Dean T,Kievit P,Sullivan EL,Friedman JE,Grove K,Aagaard KM

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:The increase in resistance to antibiotics among disease-causing bacteria necessitates the development of alternative antimicrobial approaches such as the use of light-activated antimicrobial agents (LAAAs). Light of an appropriate wavelength activates the LAAA to produce cytotoxic species which can then caus...

journal_title：BMC microbiology

authors： Omar GS,Wilson M,Nair SP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Legionella pneumophila, the causative agent of Legionnaire's disease, may enter a viable but non-culturable (VBNC) state triggered by environmental stress conditions. Specific outer-membrane epitopes of L. pneumophila are used in many diagnostic applications and some of them are linked to important virulence...

journal_title：BMC microbiology

authors： Schrammel B,Petzold M,Cervero-Aragó S,Sommer R,Lück C,Kirschner A

更新日期：2018-07-17 00:00:00

abstract：ERRATUM:Upon publication of the original article (1) it was highlighted by the authors that a grant awarded to support the research work of the study was missed in the acknowledgements. It should also be acknowledged that the grant titled "Genotyping and Molecular Epidemiological Characteristic of Bacillus anthracis in...

journal_title：BMC microbiology

authors： Li S,Ma Q,Chen H,Wang D,Liu Y,Wei X,You L,Yao G,Tian K,Tang G

更新日期：2018-04-12 00:00:00

abstract：BACKGROUND:The dspA (hik33) gene, coding for a putative sensory histidine kinase, is conserved in plastids (ycf26) and cyanobacteria. It has been linked with a number of different stress responses in cyanobacteria. RESULTS:We constructed an insertional mutant of dspA (ycf26) in Synechocystis 6803. We found little phen...

journal_title：BMC microbiology

authors： Morrison SS,Mullineaux CW,Ashby MK

更新日期：2005-08-02 00:00:00

abstract：BACKGROUND:Thermotolerant Campylobacter is among the more prevalent bacterial pathogens that cause foodborne diseases. This study aimed at evaluating the occurrence of thermotolerant Campylobacter contamination in chicken carcasses and processing plant stations (chilling water, scalding water, defeathering machinery, e...

journal_title：BMC microbiology

authors： Figueroa G,Troncoso M,López C,Rivas P,Toro M

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:Although Aspergillus fumigatus is an important human fungal pathogen there are few expression systems available to study the contribution of specific genes to the growth and virulence of this opportunistic mould. Regulatable promoter systems based upon prokaryotic regulatory elements in the E. coli tetracycl...

journal_title：BMC microbiology

authors： Vogt K,Bhabhra R,Rhodes JC,Askew DS

更新日期：2005-01-13 00:00:00

abstract：BACKGROUND:We performed a 12-month cohort study of the stability and resilience of the intestinal microbiota of healthy children in daycare in Denmark in relation to diarrheal events and exposure to known risk factors for gastrointestinal health such as travelling and antibiotic use. In addition, we analyzed how gut mi...

journal_title：BMC microbiology

authors： Mortensen MS,Hebbelstrup Jensen B,Williams J,Brejnrod AD,O'Brien Andersen L,Röser D,Andreassen BU,Petersen AM,Stensvold CR,Sørensen SJ,Krogfelt KA

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:Gene knockouts are a common tool used to study gene function in various organisms. However, designing gene knockouts is complicated in viruses, which frequently contain sequences that code for multiple overlapping genes. Designing mutants that can be traced by the creation of new or elimination of existing r...

journal_title：BMC microbiology

authors： Taylor LJ,Strebel K

更新日期：2017-01-07 00:00:00

abstract：BACKGROUND:Iron is an essential nutrient but can be toxic at high intracellular concentrations and organisms have evolved tightly regulated mechanisms for iron uptake and homeostasis. Information on iron management mechanisms is available for organisms living at circumneutral pH. However, very little is known about how...

journal_title：BMC microbiology

authors： Osorio H,Martínez V,Nieto PA,Holmes DS,Quatrini R

更新日期：2008-11-24 00:00:00

abstract：BACKGROUND:Anthrax, the zoonotic disease caused by the gram-positive bacterium Bacillus anthracis, is nowadays rare in northern parts of Europe including Finland and Scandinavia. Only two minor outbreaks of anthrax in 1988 and in 2004 and one sporadic infection in 2008 have been detected in animals in Finland since the...

journal_title：BMC microbiology

authors： Lienemann T,Beyer W,Pelkola K,Rossow H,Rehn A,Antwerpen M,Grass G

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is generally employed for the rapid identification of fungal isolates. However, the results are based on s...

journal_title：BMC microbiology

authors： Nakamura S,Sato H,Tanaka R,Kusuya Y,Takahashi H,Yaguchi T

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Iron plays important roles in the growth, reproduction and pathogenicity of Aeromonas hydrophila. In this study, we detected and compared the mRNA and protein expression profiles of A. hydrophila under normal and iron restricted medium with 200 μM 2,2-Dipyridyl using RNA Sequencing (RNA-seq) and isobaric tag...

journal_title：BMC microbiology

authors： Teng T,Xi B,Chen K,Pan L,Xie J,Xu P

更新日期：2018-06-04 00:00:00