Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Coun

Abstract:

AIM OF THE REVIEW:To review the epidemiology, pathophysiology, treatment and prognostication in relation to the post-cardiac arrest syndrome. METHODS:Relevant articles were identified using PubMed, EMBASE and an American Heart Association EndNote master resuscitation reference library, supplemented by hand searches of key papers. Writing groups comprising international experts were assigned to each section. Drafts of the document were circulated to all authors for comment and amendment. RESULTS:The 4 key components of post-cardiac arrest syndrome were identified as (1) post-cardiac arrest brain injury, (2) post-cardiac arrest myocardial dysfunction, (3) systemic ischaemia/reperfusion response, and (4) persistent precipitating pathology. CONCLUSIONS:A growing body of knowledge suggests that the individual components of the post-cardiac arrest syndrome are potentially treatable.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Nolan JP,Neumar RW,Adrie C,Aibiki M,Berg RA,Böttiger BW,Callaway C,Clark RS,Geocadin RG,Jauch EC,Kern KB,Laurent I,Longstreth WT,Merchant RM,Morley P,Morrison LJ,Nadkarni V,Peberdy MA,Rivers EP,Rodriguez-Nunez A,S

doi

10.1016/j.resuscitation.2008.09.017

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

350-79

issue

3

eissn

0300-9572

issn

1873-1570

pii

S0300-9572(08)00678-3

journal_volume

79

pub_type

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