Topical treatment for phimosis: time span and other factors behind treatment effectiveness.

Abstract:

OBJECTIVE:To study the factors that may influence the effectiveness of 0.2% betamethasone/hyaluronidase cream in the treatment of phimosis. METHODS:We treated 427 patients (3-10 years old, mean 6.33) in a prospective, randomized, blind study, with 214 patients on a 4-week and 213 patients on an 8-week course. All patients were seen once monthly at least for 6 months after the end of treatment. The penis was photographed to allow objective evaluation of treatment response. The therapeutic response was graded as total success when there was complete exposure of the glans; partial success when there was exposure of half of the glans, impeded by balanopreputial adherence or ring fibrosis at the prepuce; and therapeutic failure when patients had no or less than 50% glans exposure. RESULTS:After treatment 92.1% of patients showed total or partial success, but during follow up (mean 9.36 months, range 6-13) 29.5% failed to maintain this (22.6% and 37.6% for 8- and 4-week treatment, respectively). During treatment, 13.6% presented side effects or complications: prepuce ardor (6.1%), hyperemia (4.6%), paraphimosis (0.0098%). Intervention or interruption of treatment was unnecessary. The two groups were statistically similar in all parameters, but time of treatment=8 weeks, previous urethral meatal exposure and no previous balanoposthitis increased the chance of total success. Surgery was indicated for failure or relapse in 181 patients (42.38%). CONCLUSION:Treatment with topical 0.2% betamethasone/hyaluronidase cream for 8 weeks is effective and safe, especially if the urethral meatus is exposed and there is no previous balanoposthitis. Rescue treatment is not recommended, as the results were not encouraging.

journal_name

J Pediatr Urol

authors

Garcia de Freitas R,Nobre YD,Demarchi GT,Hachul M,Macedo A Jr,Srougi M,Ortiz V

doi

10.1016/j.jpurol.2006.05.006

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

380-5

issue

4

eissn

1477-5131

issn

1873-4898

pii

S1477-5131(06)00096-9

journal_volume

2

pub_type

杂志文章
  • Hypospadias anatomy: Elastosonographic evaluation of the normal and hypospadic penis.

    abstract:BACKGROUND:Hypospadias is one of the most common congenital anomalies in childhood. The aim of this study is to apply elastosonography on normal and hypospadic penis to verify the structural differences in tissues composition and stiffness. MATERIALS AND METHODS:We analyzed medical chart of patients treated at our Ins...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2016.02.007

    authors: Camoglio FS,Bruno C,Zambaldo S,Zampieri N

    更新日期:2016-08-01 00:00:00

  • Hydronephrosis and crossing vessels in children: Optimization of diagnostic-therapeutic pathway and analysis of color Doppler ultrasound and magnetic resonance urography diagnostic accuracy.

    abstract:INTRODUCTION:Ureteropelvic junction obstruction (UPJO) is one of the most frequent urological diseases affecting the pediatric population. It can be due to both intrinsic stenosis of the junction and extrinsic causes such as the presence of crossing vessels (CVs), which can be detected by color Doppler ultrasound (CD-U...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2017.09.019

    authors: Wong MCY,Piaggio G,Damasio MB,Molinelli C,Ferretti SM,Pistorio A,Ghiggeri G,Degl'Innocenti ML,Canepa A,Incarbone V,Mattioli G

    更新日期:2018-02-01 00:00:00

  • Extensive skin bridging with glans epithelium replacement by penile shaft skin following newborn circumcision.

    abstract:INTRODUCTION:Extensive skin bridging with replacement of glans epithelium by shaft skin is an unusual complication of newborn circumcision not previously described. MATERIALS AND METHODS:Patients with extensive skin bridges and replacement of at least 50% of glans epithelium with shaft skin underwent lysis of the brid...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2006.01.010

    authors: Snodgrass W

    更新日期:2006-12-01 00:00:00

  • Assessment of urinary tract dilation grading amongst pediatric urologists.

    abstract:INTRODUCTION:The Urinary Tract Dilation (UTD) system was created to address variability in hydronephrosis grading. It is unknown if or how pediatric urologists are integrating this newer system into practice. OBJECTIVE:We sought to evaluate the current use of hydronephrosis grading systems, inter-rater reliability (IR...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.04.025

    authors: Gray MC,Zillioux JM,Varda B,Herndon CDA,Kurtz MP,Chow JS,Kern NG

    更新日期:2020-08-01 00:00:00

  • Screening for depression and anxiety in childhood neurogenic bladder dysfunction.

    abstract:INTRODUCTION:Patients with chronic illnesses are known to have anxiety disorders and are likely to be depressed. Anxiety and depression (A/D) has been studied in adults with spina bifida (SB), however, no study has directly screened for A/D in pediatric patients with neurogenic bladder (NB) and their caregivers. OBJEC...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2014.11.017

    authors: Kabra AT,Feustel PJ,Kogan BA

    更新日期:2015-04-01 00:00:00

  • Tubularized incised plate hypospadias repair for distal hypospadias.

    abstract:PURPOSE:We report surgical technique and outcomes in consecutive patients with primary distal hypospadias. MATERIALS AND METHODS:A prospectively maintained database of all patients operated by WS in 2000-2008 was reviewed for pertinent data in consecutive patients. RESULTS:A total of 551 consecutive patients of mean ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2009.09.010

    authors: Snodgrass WT,Bush N,Cost N

    更新日期:2010-08-01 00:00:00

  • Initial urological evaluation and management of children with neurogenic bladder due to myelomeningocele.

    abstract:INTRODUCTION:The proactive management of children with myelomeningocele (MMC) has contributed to decreasing their progression to end-stage renal disease, thanks to early urological evaluation and timing implementation of treatments. OBJECTIVE:To demonstrate that early urological evaluation of the urinary tract in MMC ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2016.12.024

    authors: Sager C,Burek C,Corbetta JP,Weller S,Ruiz J,Perea R,Lago E,Gomez Y,Durán V,López JC

    更新日期:2017-06-01 00:00:00

  • The Publication Ranking Score for pediatric urology: quantifying thought leadership within the subspecialty.

    abstract:OBJECTIVES:Clinical care parameters are frequently assessed by national ranking systems. However, these rankings do little to comment on institutions' academic contributions. The Publication Ranking Score (PRS) was developed to allow for objective comparisons of scientific thought-leadership at various pediatric urolog...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2013.03.012

    authors: Lloyd JC,Madden-Fuentes RJ,Nelson CP,Kokorowski PJ,Wiener JS,Ross SS,Kutikov A,Routh JC

    更新日期:2013-12-01 00:00:00

  • Reviewing definitions of urinary continence in the contemporary spina bifida literature: a call for clarity.

    abstract:BACKGROUND:Urinary continence is a common goal for children with spina bifida and their physicians. However, definitions of urinary continence vary widely across published studies. We systematically assessed the utilization of common definitions of urinary continence in the spina bifida literature. METHODS:We searched...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2013.02.006

    authors: Lloyd JC,Nseyo U,Madden-Fuentes RJ,Ross SS,Wiener JS,Routh JC

    更新日期:2013-10-01 00:00:00

  • Delaying primary closure of classic bladder exstrophy: When is it too late?

    abstract:INTRODUCTION:With current trends towards delaying the closure of classic bladder exstrophy (CBE), bladder growth rate or ultimate capacity may be impacted. OBJECTIVE:To examine consecutive bladder capacities in CBE patients who had primary closures at differing ages and determine whether there is an optimal age for cl...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.09.003

    authors: Wu WJ,Maruf M,Manyevitch R,Davis R,Harris KT,Patel HD,DiCarlo HN,Gearhart JP

    更新日期:2020-12-01 00:00:00

  • The large bladder diverticulum in children.

    abstract:OBJECTIVE:Large bladder diverticulae, i.e. with a diameter measuring at least one-third of the bladder diameter on voiding cystourethrography, constitute an unusual but serious cause of obstructive uropathy in childhood. Their operative management entails meticulous reconstruction of the lower urinary tract. We report ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2005.01.005

    authors: Bogdanos J,Paleodimos I,Korakianitis G,Stephanidis A,Androulakakis PA

    更新日期:2005-08-01 00:00:00

  • Follow-up imaging after acute evaluations for pediatric nephrolithiasis: Trends from a National database.

    abstract:BACKGROUND:Overuse of computed tomography (CT) in the initial evaluation of children with upper urinary tract calculi (UUTC) has been well documented. Follow-up imaging patterns, however, remain undefined. Sequential imaging following an acute episode of UUTC represents additional opportunity for enacting good imaging ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2018.04.019

    authors: Ellison JS,Merguerian PA,Fu BC,Holt SK,Lendvay TS,Gore JL,Shnorhavorian M

    更新日期:2018-12-01 00:00:00

  • Evaluation of parental sociocultural background and education level in response to pediatric testis torsion.

    abstract:INTRODUCTION:Acute scrotal pain (ASP) remains one of the most common male urologic emergencies in the pediatric age group. The most concerning outcome of testicular torsion (TT) is the need for orchiectomy, which has a negative impact on the child's development in general and on sexual development and psychology in par...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.09.011

    authors: Göger YE,Özkent MS,Ünlü MZ,Kocaoğlu C,Madenci H,Pişkin MM

    更新日期:2020-12-01 00:00:00

  • Successful treatment of idiopathic priapism in a 13-year-old boy.

    abstract::Priapism is a medical emergency. An idiopathic case can be a difficult clinical problem in the pediatric emergency room. This case highlights the successful use of penile irrigation and injection of phenylephrine in a 13-year-old boy with idiopathic ischemic priapism 12 h after sexual intercourse. ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2008.09.004

    authors: Palmer B,Frimberger D

    更新日期:2009-04-01 00:00:00

  • Epithelial growth factor and decompressive testicular fasciotomy to control ischemia reperfusion injury in rats.

    abstract:PURPOSE:Testicular torsion is an urological emergency and an important cause of male infertility. Recent studies have shown that not only ischemia, but also the restoration of blood flow creates a deleterious situation for the testis. The goal of this work was to evaluate the role of systemic epithelial growth factor a...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.02.018

    authors: Quintaes IPP,de Avelar GF,Quintaes AP,Boasquevisque PCR,Resende V

    更新日期:2020-06-01 00:00:00

  • Comparison of testicular volume differential calculations in adolescents with varicoceles.

    abstract:PURPOSE:We aimed to develop a conversion formula between different calculations for testicular volume asymmetry. MATERIALS AND METHODS:Male adolescents with varicoceles who underwent scrotal ultrasound were studied. Two formulas were analyzed: (1) testicular volume differential, TVDiff = (RTV - LTV)/(TTV), and (2) atr...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2013.12.007

    authors: Christman MS,Zderic SA,Kolon TF

    更新日期:2014-04-01 00:00:00

  • Neonatal circumcision reduces the incidence of asymptomatic urinary tract infection: a large prospective study with long-term follow up using Plastibell.

    abstract:OBJECTIVE:To evaluate the preventive effect of neonatal circumcision on urinary tract infection and the incidence of complications following neonatal circumcision using Plastibell. MATERIALS AND METHODS:A prospective study was carried out between 2004 and 2008. During this period, there were 3000 neonatal circumcision...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2010.10.008

    authors: Simforoosh N,Tabibi A,Khalili SA,Soltani MH,Afjehi A,Aalami F,Bodoohi H

    更新日期:2012-06-01 00:00:00

  • Is two-port laparoendoscopic single-site surgery (T-LESS) feasible for pediatric hydroceles? Single-center experience with the initial 59 cases.

    abstract:INTRODUCTION:Although T-LESS is increasingly being used to treat pediatric inguinal hernia, there is no study regarding T-LESS for pediatric hydrocele. OBJECTIVE:To further evaluate the feasibility of T-LESS and present our single-center experience for repair of pediatric hydroceles. STUDY DESIGN:From January 2016 to...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2017.09.016

    authors: Wang F,Shou T,Zhong H

    更新日期:2018-02-01 00:00:00

  • Pubic osteotomy minimal for abdominal wall closure in exstrophy bladder.

    abstract::We describe a novel 'pubic osteotomy minimal' (POM) done on body of pubis just lateral to the insertions of rectus abdominis and adductor longus muscles to bring rectus abdominis in midline without tension for abdominal wall closure without tension. In one patient, during pubic ramotomy, we missed middle of ramus and ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.05.003

    authors: Chatterjee US

    更新日期:2020-06-01 00:00:00

  • Urethral length in girls with lower urinary tract symptoms and forme fruste of female epispadias.

    abstract:PURPOSE:To investigate systematically the length of the urethra in girls with lower urinary tract symptoms. MATERIALS AND METHODS:In a group of 121 consecutive girls presented at a tertiary referral clinic for urinary incontinence or recurrent urinary tract infections, urethral length was measured by perineal ultrasou...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2009.10.013

    authors: Hirdes MM,de Jong TP,Dik P,Vijverberg MA,Chrzan R,Klijn AJ

    更新日期:2010-08-01 00:00:00

  • Laparoscopic pediatric pyeloplasty using the Flexdex® articulating needle driver: step-by-step video.

    abstract::Ureteropelvic junction (UPJ) stenosis is the most common cause of pathological neonatal hydronephrosis. UPJ obstruction may be treated conservatively in some cases, but surgery is indicated if symptoms occur or renal function deteriorates. Pyeloplasty is the procedure of choice for UPJ stenosis. Pyeloplasty can be per...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2019.03.022

    authors: Gorgen ARH,Araldi M,de Oliveira Paludo A,da Silva AGT,Ghissi AJ,Fernandes AS,Tavares P,Rosito TE,Cabral RD

    更新日期:2019-08-01 00:00:00

  • Post-traumatic urethral strictures in children: what have we learned over the years?

    abstract:BACKGROUND:Urethral stricture presents an uncommon but difficult urological problem in the pediatric population. Treatment protocols are different from in adults due to anatomical considerations. MATERIAL AND METHODS:A thorough manual and Medline search was conducted to review the existing literature on post-traumatic...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jpurol.2011.06.004

    authors: Ranjan P,Ansari MS,Singh M,Chipde SS,Singh R,Kapoor R

    更新日期:2012-06-01 00:00:00

  • Congenital megaprepuce: a 12-year experience (52 cases) of this specific form of buried penis.

    abstract:OBJECTIVE:Congenital megaprepuce is a specific form of buried penis. Children affected by this malformation usually suffer from a subjective difficulty in voiding which is the main indication for early surgical correction. The aim of this study was to report a single center's 12-year experience in the treatment of mega...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2012.10.010

    authors: Rod J,Desmonts A,Petit T,Ravasse P

    更新日期:2013-12-01 00:00:00

  • Metabolic risk factors and the role of prophylaxis in pediatric urolithiasis.

    abstract::Suppose that the recurrence in pediatric urolithiasis has a close relationship with metabolic abnormalities and is affected by residual burden and prophylaxis. If so, the recurrence rates could be reduced with effective surgery and appropriate prophylaxis. Here we retrospectively evaluate the metabolic risk factors da...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.12.003

    authors: Üntan İ,Üntan S,Tosun H,Demirci D

    更新日期:2020-12-06 00:00:00

  • Efficacy and safety of Mirabegron as adjuvant treatment in children with refractory neurogenic bladder dysfunction.

    abstract:INTRODUCTION:When patients with neurogenic bladder become refractory, there are different alternatives, such as the use of β3-adreceptor agonists. The aim of the present study is to evaluate efficacy and safety of Mirabegron as adjuvant treatment. MATERIAL AND METHODS:37 patients under 18 years of age who underwent Mi...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2020.07.020

    authors: Sager C,Sanmartino M,Burek C,Gomez YR,Vazquez Patiño M,Weller S,Ruiz J,Lopez Imizcoz F,Tessi C,Szklarz T,Corbetta JP

    更新日期:2020-10-01 00:00:00

  • Evaluation of the United States pediatric urology workforce and fellowships: a series of surveys performed in 2006-2010.

    abstract:OBJECTIVE:In the US, there has been an evolution in the practice of pediatric urology from a primary academic sub-specialty focused on reconstruction of major congenital genitorurinary abnormalities to a mixed academic and private practice that serves as the primary care giver for all pediatric urologic concerns. The e...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2010.12.009

    authors: Husmann DA,Routh JC,Hagerty JA,Cannon GM,Gomez P,Cheng EY,Skoog S

    更新日期:2011-08-01 00:00:00

  • Prevalence and predictors of childhood enuresis in southwest Nigeria: Findings from a cross-sectional population study.

    abstract:INTRODUCTION:Childhood enuresis is common, but the prevalence and factors associated with childhood enuresis in Africa have been poorly described. Furthermore, most studies from the continent have not provided data distinguishing monosymptomatic from non-monosymptomatic enuresis. This distinction is important as it gui...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2015.06.009

    authors: Esezobor CI,Balogun MR,Ladapo TA

    更新日期:2015-12-01 00:00:00

  • Variations in the management of asymptomatic adolescent grade 2 or 3 left varicoceles: a survey of practitioners.

    abstract:OBJECTIVE:Our study aims to evaluate variations in management of asymptomatic adolescent grade 2 and 3 varicoceles by pediatric urologists. SUBJECTS AND METHODS:Electronic survey of all 267 current members of AAP Urology with 74 (28%) responding. RESULTS:When managing patients with positive examination findings, 49% ...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2013.11.001

    authors: Coutinho K,McLeod D,Stensland K,Stock JA

    更新日期:2014-06-01 00:00:00

  • Pediatric urolithiasis in a non-endemic country: a single center experience from The Netherlands.

    abstract:OBJECTIVE:To provide insight in causative factors of pediatric urolithiasis in The Netherlands, a non-endemic country. PATIENTS AND METHODS:Data from 71 children with urolithiasis and stone analyses between 1996 and 2010 in the Radboud University Nijmegen Medical Centre were studied retrospectively. Patients (48 boys,...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2013.07.019

    authors: Rellum DM,Feitz WF,van Herwaarden AE,Schreuder MF

    更新日期:2014-02-01 00:00:00

  • Remote consultations in paediatric urology-Not just for pandemics?

    abstract::Although some centres have successfully integrated remote clinics into their paediatric urological practice, for many, remote clinics have developed due to the COVID-19 pandemic. One UK-based institution has integrated remote clinics in their practice for over two years and has developed guidelines considering which c...

    journal_title:Journal of pediatric urology

    pub_type: 杂志文章

    doi:10.1016/j.jpurol.2021.01.001

    authors: Charnell AM,Hoen L',Sforza S,Spinoit AF,Radford A

    更新日期:2021-01-06 00:00:00