Abstract：
:Poisonous plants and animals are widespread in nature and have been used for a great variety of purposes. Brief discussions of a number of examples: aconite, ergot, Euphorbiaceae/Thymelaeaceae, curare, cardiac glycosides, triterpenoid saponins and animal toxins, make the point that, in addition to allowing their use as medicinal agents, the study of such substances has opened up new areas of (bio)chemistry, physiology and pharmacology. But even though the compounds concerned have a relatively low molecular weight, in some cases their examination had to wait until appropriate methods of investigation became available. Understanding the modes of action has allowed the molecules to be used as starting points for the development of useful medicinal agents, a better appreciation of structure-activity relationships having led to improvements in the properties desired. With the advent of methods for the investigation of high-molecular-weight proteins, polypeptides, polyketides, etc., it is now possible to enter entirely new fields and to study more complex materials derived from plant, animal and other sources. It is here that future developments, coupled with the possibility of more specific targeting, hold most promise for the beneficial utilization of otherwise highly poisonous substances.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Bisset NGdoi
10.1016/0378-8741(91)90105-msubject
Has Abstractpub_date
1991-04-01 00:00:00pages
71-81issue
1-3eissn
0378-8741issn
1872-7573pii
0378-8741(91)90105-Mjournal_volume
32pub_type
杂志文章,评审abstract：AIM OF THE STUDY:The in vivo effects of Tulbhagia violacea on systemic arterial blood pressure and on the renin-angiotensin system in a Dahl salt-sensitive rat model were investigated. MATERIALS AND METHODS:Animals were treated for 14 days intraperitoneally as follows: Tulbhagia violacea (Tvl) (50mg/kg b.w.), captopri...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.01.040
更新日期：2008-05-08 00:00:00
abstract：:This research aims to study the metabolism and pharmacokinetics of phytoestrogen kobophenol A (1), the main active compound of Caragana sinica (Buc'hoz) Rehd. (Fabaceae), in rats. Metabolites of 1 in rats' feces were isolated and purified by multi-chromatograph techniques; three new metabolites of 1, named koboquinone...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.05.016
更新日期：2005-10-03 00:00:00
abstract：:A single or repeated administration of morphine in mice produced hyperactivity, conditioned place preference (CPP) and postsynaptic dopamine (DA) receptor supersensitivity. The hyperactivity induced by morphine was evidenced by measuring the enhanced ambulatory activity using a tilting-type ambulometer. CPP effects we...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(97)00131-1
更新日期：1998-02-01 00:00:00
abstract：:Prostate cancer (PC) is the most prevalent cancer and the leading cause of male cancer death. Azadirachta indica (neem tree) has been used successfully centuries to reduce tumors by herbalists throughout Southeast Asia. Here the present study indicated that an ethanolic extract of neem has been shown to cause cell dea...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.11.006
更新日期：2006-04-21 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Viscum articulatum Burm. f. (leafless mistletoe) has been used in traditional system of medicines in India, China, Taiwan, Cambodia, Laos, and Vietnam, to treat blood-related diseases and various inflammatory and degenerative diseases including cancer. Anticancer activities of some phytom...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.03.005
更新日期：2018-06-12 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Nymphaea hybrida Peck is used as a traditional medicinal herb for treating pain and inflammatory diseases, and known for its ornamental value and as a hot drink. However, the effects of N. hybrida polar fractions on lipopolysaccharide (LPS)-induced in vitro inflammation model and acute in...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113698
更新日期：2021-04-06 00:00:00
abstract：:Biopiracy accusations are common in the world of biodiversity research. At the end of 2015, a French NGO accused researchers from the Institut de Recherche pour le Développement (IRD) of biopiracy. These researchers had applied for a patent for a natural bioactive molecule against malaria and cancer, the Simalikalacto...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2017.05.030
更新日期：2017-07-12 00:00:00
abstract：:The antihypertensive action of a procyanidin glycoside isolated from Rhamnus lycioides aerial parts was studied in spontaneously and renal hypertensive rats. This compound, like 20 micrograms/kg i.v. of captopril, produced a very clear in vivo inhibition of angiotensin I converting enzyme when given at a dose of 3 mg/...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(91)90149-8
更新日期：1991-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The lack of ethnoveterinary surveys in Brazil, especially in the Amazon region, results in losses in the veterinary phytopharmacology field and in scientific documentation of the cultural traditions of plant use in the treatment of animal diseases. AIM OF THE STUDY:To catalog, analyze an...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2012.09.018
更新日期：2012-11-21 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Quercus Infectoria galls (QIG) have a long history of use in traditional Chinese medicine and traditional Uyghur medicine for the treatment of diarrhea, hemorrhage, skin disease, and many other human ailments. Medicinal applications of QIG have become increasingly popular in Greece, Asia ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2020.113592
更新日期：2020-11-17 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Rhizoma alismatis (simplified as RA, "Zexie" in Chinese, ) is a well-known natural medicine with long history in Chinese medicine. As a traditional medicine in China, RA is an important part of many prescriptions and has been commonly used for treating a wide range of ailments related to ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2014.10.061
更新日期：2014-12-02 00:00:00
abstract：AIM OF THE STUDY:Asthma is a disease marked by airway inflammation. Petasites japonicus (Pj) is known as an herb for treating asthma, oxidant stress and gastric ulcer in traditional Oriental medicine. In this study, the inhibitory effects of Pj extract on asthmatic responses were examined both in vitro and in vivo. MA...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2010.10.038
更新日期：2011-01-27 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCES:One of the prestigious Thai/Lanna folklore wisdoms is the medicinal plant recipes. Thai/Lanna medicinal plant recipe database MANOSROI III has been developed by Prof. Dr. Jiradej Manosroi. It consists of over 200,000 recipes covering all diseases including cancer. AIM OF THIS STUDY:To i...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.06.037
更新日期：2013-08-26 00:00:00
abstract：AIM OF THE STUDY:Despite the extensive traditional use of Croton gratissimus Burch. var. gratissimus for medicinal purposes, scientific studies validating the therapeutic properties of this indigenous plant are lacking. As the bark, roots and leaves of C. gratissimus are used separately as well as in combination, this ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.06.031
更新日期：2008-10-28 00:00:00
abstract：:Propolis collected from a cerrado area in Minas Gerais State, Brazil, was subjected to chromatography on silica gel column and to partition between immiscible solvents. Propolis aqueous-ethanolic extract and fractions obtained were tested for inhibitory activity against periodontitis-causing bacteria. All of the assay...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(02)00003-x
更新日期：2002-04-01 00:00:00
abstract：:The use of plants as medicine has been referred to since ancient peoples, perhaps as early as Neanderthal man. Plants are a source of many biologically active products and nowadays they are of great interest to the pharmaceutical industry. The study of how people of different culture use plants in particular ways has ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2004.12.014
更新日期：2005-04-08 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Da Chuanxiong Formula (DCXF) is one of the famous herb pairs that contains dried rhizomes of Ligusticum chuanxiong Hort. and Gastrodia elata Bl. in the mass ratio of 4:1. This classic representative traditional Chinese medicine has been widely used to treat brain diseases like headache an...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.02.004
更新日期：2018-05-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Rhodiola algida, an herb ingredient used in Chinese medicine, has been clinically proven to be effective in enhancing human immune responses. AIM OF STUDY:This study attempted to identify the potential immunomodulatory effect of Rhodiola algida extract in human immune system in vitro, an...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.03.009
更新日期：2009-06-22 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cedrus deodara (Roxb. ex D.Don) G. Don is applied as anti-inflammatory and anti-infection agents in folklore medicine. AIM OF THE STUDY:The present study aimed to assess the antimicrobial activity of Cedrus deodara (Roxb. ex D.Don) G. Don extract (CDE) against Streptococcus mutans biofil...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.112856
更新日期：2020-07-15 00:00:00
abstract：:The aerial parts of Tilia americana var. mexicana (Schltdl) Hardin (Tiliaceae) have been widely used in Mexican traditional medicine to relieve sleeplessness, headache, and nervous excitement. The anxiolytic effect of four extracts and several flavonoid fractions from the bracts of Tilia americana subsp.mexicana, var....
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.04.019
更新日期：2008-07-23 00:00:00
abstract：:The hepatoprotective activity of the aqueous-methanolic extract of Artemisia maritima was investigated against acetaminophen (paracetamol, 4-hydroxy acetanilide)- and carbon tetrachloride (CCl4)-induced hepatic damage. Acetaminophen produced 100% mortality at the dose of 1 g/kg in mice, while pretreatment of animals w...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(95)01252-9
更新日期：1995-06-23 00:00:00
abstract：:Omic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2012.01.055
更新日期：2012-04-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Maytenus ilicifolia Mart. ex. Reissek (Celastraceae) is widely used in Brazilian folk medicine to treat gastric disturbances. AIM OF THE STUDY:This work intended to characterize the effects of Maytenus ilicifolia on gastrointestinal motility. MATERIALS AND METHODS:Gastric emptying and i...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.03.037
更新日期：2009-06-25 00:00:00
abstract：:This paper focusses on Xhosa healers and their pharmacopoeias in Southern Africa. Its preliminary aim is to show that Xhosa healers have incorporated Western pharmaceutical products into their traditional dispensaries. The primary aim of the paper is to explain the trend towards medicinal incorporation in terms of the...
journal_title：Journal of ethnopharmacology
pub_type： 历史文章,杂志文章
doi：10.1016/0378-8741(91)90083-p
更新日期：1991-07-01 00:00:00
abstract：:Sixty-six extracts of 18 plants commonly used by traditional healers in Congo Brazzaville for the treatment of malaria have been investigated for in vitro antiplasmodial activity. Ethanolic and dichloromethane extracts of 7 among the 18 studied plants were moderately active (10 microg/ml journal_title：Journal of ethnopharmacology pub_type： 杂志文章 doi：10.1016/j.jep.2005.08.068 更新日期：2006-03-08 00:00:00
abstract：:Recent research suggests that, in addition to the well-documented occurrence of significant quantities of cocaine and related alkaloids in a limited number of species, the genus Erythroxylon will prove to be a rich source of tropane alkaloids. These bases are esters of a range of acids with tropine, 3 alpha, 6 beta-di...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(81)90057-x
更新日期：1981-03-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Ling-Gui-Zhu-Gan Decoction (LGZGD) formula, derived from traditional Chinese medicine (TCM), has definitive clinical efficacy in the treatment of heart failure (HF) in China. However, little is known of the underlying mechanism of LGZGD. AIM OF THE STUDY:The aim of this work was to inves...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112397
更新日期：2020-03-25 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The aqueous extract of the plant Malmpyrum pratense (Mp), is widely used in traditional medicine as a sedative, yet the biological basis of its action is not known. AIM OF THE STUDY:The effects of Mp on network activity and intrinsic and synaptic properties were studied in cultured hippo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2015.01.036
更新日期：2015-04-02 00:00:00
abstract：:Essential oil, ethanolic extract and decoction of 10 plant species from interior Portugal were analyzed for their activity towards acetylcholinesterase (AChE) enzyme and their antioxidant activity. Of these, Melissa officinalis, Paronychia argentea, Sanguisorba minor, Hypericum undulatum and Malva silvestris are used ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2006.04.010
更新日期：2006-11-03 00:00:00
abstract：:In this work we studied in rat the diuretic activity of Opuntia ficus indica (L.) Mill. (Cactaceae) waste matter. The cladodes, flowers and non commerciable fruits were collected in S. Cono (CT, Sicily) cultivation. Acute and chronic diuretic activity of 15% infusion of cladodes, flowers and fruits were assayed. Natri...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00337-3
更新日期：2002-01-01 00:00:00
