Abstract:
BACKGROUND:828 elderly subjects residing in nursing homes were followed up during 4 months to ascertain incidence of symptoms associated with Pontiac fever (PF) in a non-epidemic setting. METHODS:The exposure situation was inhalation of Legionella bacteria while showering. An audit of the hot water system in all institutions allowed ascribing each subject to a water quality area wherefrom one shower was sampled for Legionella assays at the end of the follow-up period. Legionella were detected in water and aerosols using the culture (CFU, colony forming units) and in situ hybridization (FISH) techniques. RESULTS:Among 32 Pontiac-like episodes, 29 cases complied with the operational definition of PF elaborated for this study. Incidence density was 0.11 case/person-year (95% CI 0.07 to 0.15). Water concentrations greater than 105 Legionella FISH/l and 104 Legionella CFU/l were associated with an increased risk of PF (respectively RR 2.23, p = 0.05 and RR 2.39, p = 0.11, with significant dose-response patterns: p for trend <0.04). The condition also seems associated with aerosol concentrations above 103 Legionella FISH/l of air. A significantly higher risk of Pontiac-like episodes (RR 6.24, 95% CI 2.12 to 18.38) was seen for elderly subjects receiving corticosteroid therapy. CONCLUSION:The water and threshold values identified in this research could be used to inform guidance measures aimed at protecting institutionalised older people from Legionnaires' disease. Immunosuppressive therapy in the same population group can significantly enhance susceptibility to Legionella bacteria.
journal_name
J Epidemiol Community Healthjournal_title
Journal of epidemiology and community healthauthors
Bauer M,Mathieu L,Deloge-Abarkan M,Remen T,Tossa P,Hartemann P,Zmirou-Navier Ddoi
10.1136/jech.2007.063784subject
Has Abstractpub_date
2008-10-01 00:00:00pages
913-20issue
10eissn
0143-005Xissn
1470-2738pii
62/10/913journal_volume
62pub_type
杂志文章,多中心研究abstract:BACKGROUND:Research on ethnic differentials in mortality in England and Wales has focused on immigrants because, until now, studies collecting data on ethnicity have not covered sufficient deaths to investigate the subject. International migrants are selected for good health and tend to have low mortality. METHODS:We ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2012-202265
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:The use of validated multivariate cardiovascular predictive models in a population setting is of interest for public health policy makers. We aimed to validate the estimations of the CASSANDRA model (coronary heart disease (CHD) incidence and CHD risk distribution), considering the population changes in age,...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2013-203516
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To elucidate whether the risk of macrosomia, large for gestational age (LGA) and small for gestational age (SGA) is influenced by maternal body mass index and glucose tolerance differently in male and female fetuses. METHODS:A population study was conducted in 16 general hospitals from the Spanish National H...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究
doi:10.1136/jech.2008.074542
更新日期:2009-01-01 00:00:00
abstract::This study was conducted at the paediatric emergency department of a tertiary care teaching and referral hospital in Kabul, Afghanistan to assess the morbidity and mortality pattern of illness in paediatric population. Afghanistan has one of the highest infant mortality rates in the world, and there is complete breakd...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2005.040147
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To raise compliance in a general practice based colorectal cancer screening programme by the use of a simple health educational leaflet. DESIGN:A randomised controlled trial of the leaflet's effect on completion of faecal occult blood tests. The leaflet explained the high frequency of colorectal cancer, the ...
journal_title:Journal of epidemiology and community health
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/jech.51.2.187
更新日期:1997-04-01 00:00:00
abstract::This essay examines the implications of the COVID-19 pandemic for health inequalities. It outlines historical and contemporary evidence of inequalities in pandemics-drawing on international research into the Spanish influenza pandemic of 1918, the H1N1 outbreak of 2009 and the emerging international estimates of socio...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2020-214401
更新日期:2020-11-01 00:00:00
abstract::The perinatal mortality rates of mothers who delivered at St. Thomas's Hospital from 1969 to 1976 have been examined. The rate in the West Indian population was significant higher than in the United Kingdom white population. The increased West Indian mortality was confined to infants with a birth weight of more than 2...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.36.1.22
更新日期:1982-03-01 00:00:00
abstract:STUDY OBJECTIVE:The aim was to quantify the difference in precision of risk estimates in epidemiology between the situations where misclassification of exposure is corrected for by external validation and where it is corrected for by internal repeat measurement. Precision was measured in terms of the expected width of ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.46.6.620
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Frailty is a way to appreciate the variable vulnerability to declining health status of people as they age. No consensus for measuring frailty has been established. This study aimed to adapt a Frailty Index (FI) to the Canadian Longitudinal Study on Aging (CLSA) and evaluate its applicability in both younger...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2016-208853
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:To assess the effect of the Demerit Point System (DPS), introduced in Spain on 1 July 2006, on the number of fatalities due to road traffic accidents, using a methodology that controls for the seasonal variation and trend in the data series. METHODS:Time-series analysis by ARIMA models of 29 113 fatalities ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.082461
更新日期:2010-03-01 00:00:00
abstract::In February and May 1986, weekly samples of whole pasteurised milk were collected from the 24 dairies supplying seven British towns. A random sample of 96 women aged 25-64 was drawn from general practitioners' lists in each town, and catch specimens of early morning urine were collected by post from 194 subjects in Fe...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.42.1.72
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:Efforts to end preventable newborn deaths will fail if the poor are not reached with effective interventions. To understand what works to reach vulnerable groups, we describe and explain the uptake of a highly effective community-based newborn health intervention across social strata in Asia and Africa. MET...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-204685
更新日期:2016-01-01 00:00:00
abstract:STUDY OBJECTIVE:To examine whether neighbourhood deprivation predicts incidence rates of coronary heart disease, beyond age and individual income. DESIGN:Follow up study from 31 December 1995 to 31 December 1999. Women and men were analysed separately with respect to incidence rates of coronary heart disease. Multilev...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.58.1.71
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The evidence on mortality patterns by education in Spain comes from regional areas. This study aimed to estimate these patterns in the whole Spanish population. METHODS:All citizens aged 25 years and over and residing in Spain in 2001 were followed during 7 years to determine their vital status, resulting i...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-204186
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:This study examines the politics of appropriating Question 1 tobacco tax revenues in the first budget year after Massachusetts voters passed the ballot initiative in 1992. The initiative increased the tobacco tax on cigarettes by 25 cents per pack and on smokeless tobacco by 25% of the wholesale price. METHO...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.56.7.522
更新日期:2002-07-01 00:00:00
abstract::The Global Polio Eradication Initiative to eradicate polio completely by the year 2000 has been successful, except for three endemic and some non-endemic countries. Pakistan, one of the three endemic polio reservoirs, is posing a serious threat to the success of the initiative. Currently, the expanded programme on imm...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech-2012-202162
更新日期:2013-08-01 00:00:00
abstract:STUDY OBJECTIVE:The aim of the study was to examine a cohort of cases of childhood cancer occurring in a defined geographical area to try to identify clustering and possible causative factors. DESIGN:Data were analysed using the close pair method developed by Knox for signs of clustering in relation to date and place ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.44.1.55
更新日期:1990-03-01 00:00:00
abstract:STUDY OBJECTIVE:The aims were (1) to assess whether termination of pregnancy after prenatal screening by ultrasound affected the prevalence of congenital anomalies at birth, and (2) to examine the trend of this pattern over time. DESIGN:This study deals with congenital anomalies, possibly detectable prenatally or at b...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.48.3.290
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:In 1998, highly active antiretroviral therapy (HAART) was widespread, but the diffusion of these life-saving treatments was not uniform. As half of all AIDS patients in the USA have Medicaid coverage, this study of a multistate Medicaid claims dataset was undertaken to assess disparities in the rates of HAAR...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究
doi:10.1136/jech.2005.045567
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To explore attitudes to quitting smoking and experience of smoking cessation among Bangladeshi and Pakistani ethnic minority communities. DESIGN:Qualitative study using community participatory methods, purposeful sampling, interviews and focus groups, and a grounded approach to data generation and analysis. ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2005.040345
更新日期:2006-05-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2009.107441
更新日期:2011-07-01 00:00:00
abstract::A commonly used estimate of a screening test's sensitivity, based on the prevalence at screening and the incidence of interval cancers, is shown to be logically unsound and quantitatively poor. An alternative simple estimate is proposed, based only on incidence rates. ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.39.4.364
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND:To inform discussions on rates, burden and priority-setting in relation to police violence, we quantified the number and rate of years of life lost (YLLs) due to police violence by race/ethnicity and age in the USA, 2015-2016. METHODS:We used data on the number of deaths due to police violence from 'The Cou...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2017-210059
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:There is a growing interest in understanding the connection between mental illness (MI) and the onset of new physical illnesses among previously physically healthy individuals. Yet the role of gender is often forgotten in research focused on comorbidity of health problems. The objective of this study was to ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2013-202838
更新日期:2014-01-01 00:00:00
abstract:STUDY OBJECTIVE:Northern Ireland has the highest standardised mortality ratios for colon cancer in the United Kingdom and the Republic of Ireland has some of the highest mortality rates for cancer in the world. The aim of the study therefore was to investigate trends in colorectal cancer in the north and south of Irela...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.44.3.220
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Maternal exposure to ambient air pollution has been associated with higher risk of preterm birth and reduced fetal growth, but heterogeneity among prior studies suggests that additional studies are needed in diverse populations and settings. We examined the associations between maternal ambient air pollution...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2017-208963
更新日期:2017-12-01 00:00:00
abstract:STUDY OBJECTIVE:A statistical test that allows for adjustment of confounding can be helpful for the study of seasonal patterns. The aim of this article is to supply a detailed description of such a method. An example of its application is given. DESIGN:A statistical test is presented that retains the information on th...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.53.4.235
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:The temporal pattern of effects of summertime ozone (O(3)) in total, cardiovascular and respiratory mortality were investigated in 21 European cities participating in the APHEA-2 (Air Pollution and Health: a European Approach) project, which is fundamental in determining the importance of the effect in terms...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究
doi:10.1136/jech.2008.084012
更新日期:2009-12-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate methods for calculating life expectancy in small areas, for example, English electoral wards. DESIGN:The Monte Carlo method was used to simulate the distribution of life expectancy (and its standard error) estimates for 10 alternative life table models. The models were combinations of Chian...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2003.009654
更新日期:2004-03-01 00:00:00
abstract::Public health advocacy is the strategic use of news media to advance a public policy initiative, often in the face of opposition. ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2003.018051
更新日期:2004-05-01 00:00:00