Posttransplant diabetes and hypertension: pathophysiologic insights and therapeutic rationale.

abstract：:Recent studies support the concept that the retinal vasculature may provide a summary measure of lifetime exposure to the effects of hyperglycemia. Advances in retinal photographic techniques and in image analysis have allowed objective and precise in vivo measurement of retinal vascular changes. In particular, quanti...

journal_title：Current diabetes reports

authors： Nguyen TT,Wong TY

更新日期：2009-08-01 00:00:00

abstract：:Overnutrition is a major cause of diabetes. The contrary situation of undernutrition has also been suggested to increase the risk of the disease. Especially undernutrition during prenatal life has been hypothesized to program the structure and physiology of the fetus in such a way that it is more prone to develop diab...

journal_title：Current diabetes reports

authors： de Rooij SR,Roseboom TJ,Painter RC

更新日期：2014-10-01 00:00:00

abstract：:Among the factors predisposing to type 2 diabetes in children, adolescents, and young adults, the health and behavior of both the mother and father are critical. Prevention and treatment of parental nutritional disorders (including obesity and malnutrition), promotion of breastfeeding, and avoidance of overfeeding of ...

journal_title：Current diabetes reports

authors： Bartz S,Freemark M

更新日期：2012-02-01 00:00:00

abstract：:Diabetic nephropathy is continuing to rise in incidence, despite awareness of tight glycemic control and blood pressure. The identification that matrix accumulation is driven by transforming growth factor-beta (TGF-beta) has led to a concerted effort to apply antifibrotic strategies for this disorder. Recent studies h...

journal_title：Current diabetes reports

authors： McGowan TA,Zhu Y,Sharma K

更新日期：2004-12-01 00:00:00

abstract：:The insulin resistance syndrome (IRS) is a common disorder, which has important clinical implications. It is a cluster of cardiovascular risk factors that include obesity, hypertension, dyslipidemia, glucose intolerance, and type 2 diabetes mellitus. Lifestyle modifications and insulin sensitizers are among the severa...

journal_title：Current diabetes reports

authors： Desouza C,Gilling L,Fonseca V

更新日期：2001-10-01 00:00:00

abstract：:Type 1 and type 2 diabetes both accelerate cardiovascular disease, yet the triggers are likely different for the two types of diabetes. Results from large-scale clinical trials suggest that intense blood glucose control can reduce cardiovascular events many years later in patients with type 1 diabetes. In type 2 diabe...

journal_title：Current diabetes reports

authors： Averill MM,Bornfeldt KE

更新日期：2009-02-01 00:00:00

abstract：:Both type 1 and type 2 diabetic patients have an increased incidence of ischemic heart disease and congestive heart failure. Cardiovascular disease accounts for up to 80% of the excess mortality in patients with type 2 diabetes. The burden of cardiovascular disease is especially pronounced in diabetic women. Factors t...

journal_title：Current diabetes reports

authors： Blendea MC,McFarlane SI,Isenovic ER,Gick G,Sowers JR

更新日期：2003-06-01 00:00:00

abstract：:Type 2 diabetes is the result of a progressive impairment of pancreatic beta-cell function in the setting of worsening insulin resistance. Studies in high-risk populations have demonstrated that during progression to diabetes, beta cells have declining function and lose the first phase of insulin secretion, resulting ...

journal_title：Current diabetes reports

authors： Steppel JH,Horton ES

更新日期：2004-06-01 00:00:00

abstract：:Cell therapy has enormous potential for the treatment of conditions of unmet medical need. Cell therapy may be applied to diabetes mellitus in the context of beta cell replacement or for the treatment of diabetic complications. A large number of cell types including hematopoietic stem cells, mesenchymal stem cells, um...

journal_title：Current diabetes reports

authors： Liew A,O'Brien T

更新日期：2014-03-01 00:00:00

abstract：:Type 2 diabetes is a progressive disease characterized by the need for additional antidiabetic agents overtime to maintain a stable level of glycemic control. The discovery of the glucagon like peptide 1, 1 of the 2 major incretins, was pivotal to the development of novel therapies, which can be used in individuals wi...

journal_title：Current diabetes reports

authors： Eckerle Mize DL,Salehi M

更新日期：2013-06-01 00:00:00

abstract：:Recent estimates suggest that 1 in 12 of the global population suffers from diabetes mellitus. Approximately 40 % of those affected will go on to develop diabetes-related chronic kidney disease or diabetic nephropathy (DN). DN is a major cause of disability and premature death. Existing tests for prognostic purposes a...

journal_title：Current diabetes reports

authors： Simpson K,Wonnacott A,Fraser DJ,Bowen T

更新日期：2016-03-01 00:00:00

abstract：:The endothelium has several diverse functions in maintaining vascular integrity in terms of structure and function. Two key vasodilators, nitric oxide (NO) and prostacyclin, maintain the vascular pathway, inhibit platelet aggregation, and are antithrombotic. More recently, they have been shown to be anti-inflammatory,...

journal_title：Current diabetes reports

authors： Dandona P

更新日期：2002-08-01 00:00:00

abstract：:Continuous glucose monitoring (CGM) is an emerging technology that provides a continuous measure of interstitial glucose levels. In addition to providing a more complete pattern of glucose excursions, CGMs utilize real-time alarms for thresholds and predictions of hypo- and hyperglycemia, as well as rate of change ala...

journal_title：Current diabetes reports

authors： DeSalvo D,Buckingham B

更新日期：2013-10-01 00:00:00

abstract：:Exercise has long been recognized as a cornerstone in diabetes care. Even so, modern science is just beginning to understand the physiologic impact cardiovascular fitness has on long-term diabetes management, and the prevention or delay, of type 2 diabetes. Recent advances in research are defining the metabolic pathwa...

journal_title：Current diabetes reports

authors： Mullooly C

更新日期：2002-10-01 00:00:00

abstract：:Bariatric surgery has emerged as the most durably effective treatment of type 2 diabetes (DM). However, the mechanisms governing improvement in glucose homeostasis have yet to be fully elucidated. In this review we discuss the various types of surgical interventions and the multitude of factors that potentially mediat...

journal_title：Current diabetes reports

authors： Nguyen KT,Korner J

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Studies have shown that disasters may exacerbate the comorbidities in vulnerable populations such as those with a pre-existing chronic medical condition like diabetes. This article highlights recent studies that look at the impact of disasters on people with diabetes and also shows recent resources fo...

journal_title：Current diabetes reports

authors： Allweiss P

更新日期：2019-11-20 00:00:00

abstract：PURPOSE OF REVIEW:We highlight the unique properties of the sodium-glucose cotransporter-2 (SGLT-2 inhibitors) which may lend favorably to their efficient integration in the background of other heart failure (HF) therapies. We also discuss the unique aspects of SGLT-2 inhibitor dosing, lack of titration needs, effects ...

journal_title：Current diabetes reports

authors： Khan MS,Vaduganathan M

更新日期：2020-10-11 00:00:00

abstract：:Erectile dysfunction (ED) is more commonly seen in men with various components of the metabolic syndrome (a constellation of various cardiovascular and diabetes risk factors). ED can be considered as a risk marker of the metabolic syndrome and its associated conditions. The patient with ED should be thoroughly evaluat...

journal_title：Current diabetes reports

authors： Matfin G,Jawa A,Fonseca VA

更新日期：2005-02-01 00:00:00

abstract：:Diabetic patients are at increased risk for developing cardiovascular disease, and they constitute a large proportion of the global cardiovascular disease burden. Although multiple drugs exist for treating the hyperglycemia associated with diabetes, few have been shown to reduce cardiovascular risk. Great hope surroun...

journal_title：Current diabetes reports

authors： Lieb DC,McCall AL

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To introduce recent advances in the understanding of diabetic retinopathy and to summarize current and emerging strategies to treat this common and complex cause of vision loss. RECENT FINDINGS:Advances in retinal imaging and functional analysis indicate that retinal vascular and neural pathologies e...

journal_title：Current diabetes reports

authors： Honasoge A,Nudleman E,Smith M,Rajagopal R

更新日期：2019-09-10 00:00:00

abstract：:This review details the epidemiology, possible mechanisms, and risk factors associated with urogenital autonomic dysfunction in diabetes. Autonomic neuropathy in diabetes is associated with various urological complications including bladder and sexual dysfunction. Several studies have reported the high prevalence of b...

journal_title：Current diabetes reports

authors： Braffett BH,Wessells H,Sarma AV

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Diabetic retinopathy remains the leading cause of blindness among working-age US adults even though timely screening and treatment prevent 90% of blindness. We summarize current knowledge and perspectives to better understand why diabetic eye screening rates remain low and future directions towards pr...

journal_title：Current diabetes reports

authors： Liu Y,Swearingen R

更新日期：2017-08-31 00:00:00

abstract：:Neonatal hypoglycemia is an important consequence for the infant of the mother with diabetes. We have reviewed 24 published papers of various protocols for control of glucose in pregnant diabetic women during labor and delivery including our own published work. A relationship of maternal glucose during labor and neona...

journal_title：Current diabetes reports

authors： Ryan EA,Al-Agha R

更新日期：2014-01-01 00:00:00

abstract：:Diabetes is a chronic disease that affects over 25 million adults, many of whom are smokers. The negative health impact of diabetes and comorbid smoking is significant and requires comprehensive interdisciplinary management. The National Diabetes Education Program has identified specific providers, known as PPOD, who ...

journal_title：Current diabetes reports

authors： Register SJ,Harrington KF,Agne AA,Cherrington AL

更新日期：2016-09-01 00:00:00

abstract：:Hypoglycemia is a frequent occurrence in children and adolescents with type 1 diabetes. A variety of efforts have been made to standardize the definition of hypoglycemia and to define one of its most significant psychosocial consequences-fear of hypoglycemia (FOH). In addition to documenting the experience of FOH in c...

journal_title：Current diabetes reports

authors： Driscoll KA,Raymond J,Naranjo D,Patton SR

更新日期：2016-08-01 00:00:00

abstract：:In this article, we introduce the increasing prevalence of type 2 diabetes in the Japanese population and discuss the reasons for such an explosive increase. Diabetes has been brought into prominence in Japan by enhanced insulin resistance, through the change of lifestyle against the background of fragile beta-cell fu...

journal_title：Current diabetes reports

authors： Hirose T,Kawamori R

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update of glycemic management during metabolic stress related to surgery or critical illness. RECENT FINDINGS:There is a clear association between severe hyperglycemia, hypoglycemia, and high glycemic variability and poor outcomes of postoperative or critically ill patients. However, th...

journal_title：Current diabetes reports

authors： Mongkolpun W,Provenzano B,Preiser JC

更新日期：2019-11-20 00:00:00

abstract：PURPOSE OF REVIEW:A growing body of epidemiological and experimental data indicate that nutritional or environmental stressors during early development can induce long-term adaptations that increase risk of obesity, diabetes, cardiovascular disease, and other chronic conditions-a phenomenon termed "developmental progra...

journal_title：Current diabetes reports

authors： Isganaitis E

更新日期：2019-07-20 00:00:00

abstract：:The transition from intravenous (IV) to subcutaneous (SQ) insulin in the hospitalized patient with diabetes or hyperglycemia is a key step in patient care. This review article suggests a stepwise approach to the transition in order to promote safety and euglycemia. Important components of the transition include evalua...

journal_title：Current diabetes reports

authors： Kreider KE,Lien LF

更新日期：2015-05-01 00:00:00

abstract：:Hypertension and diabetes are independent risk factors for both cardiovascular disease and renal complications. Coexistence of these comorbid conditions predisposes the patient to a much greater risk of progression to end-stage renal disease. Combined with the increased cardiovascular mortality, this has led to recent...

journal_title：Current diabetes reports

authors： Newton CA,Raskin P

更新日期：2002-12-01 00:00:00