Abstract:
:Psycholinguistic research has documented a range of variables that influence visual word recognition performance. Many of these variables are highly intercorrelated. Most previous studies have used factorial designs, which do not exploit the full range of values available for continuous variables, and are prone to skewed stimulus selection as well as to effects of the baseline (e.g. when contrasting words with pseudowords). In our study, we used a parametric approach to study the effects of several psycholinguistic variables on brain activation. We focussed on the variable word frequency, which has been used in numerous previous behavioural, electrophysiological and neuroimaging studies, in order to investigate the neuronal network underlying visual word processing. Furthermore, we investigated the variable orthographic typicality as well as a combined variable for word length and orthographic neighbourhood size (N), for which neuroimaging results are still either scarce or inconsistent. Data were analysed using multiple linear regression analysis of event-related fMRI data acquired from 21 subjects in a silent reading paradigm. The frequency variable correlated negatively with activation in left fusiform gyrus, bilateral inferior frontal gyri and bilateral insulae, indicating that word frequency can affect multiple aspects of word processing. N correlated positively with brain activity in left and right middle temporal gyri as well as right inferior frontal gyrus. Thus, our analysis revealed multiple distinct brain areas involved in visual word processing within one data set.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Hauk O,Davis MH,Pulvermüller Fdoi
10.1016/j.neuroimage.2008.05.054subject
Has Abstractpub_date
2008-09-01 00:00:00pages
1185-95issue
3eissn
1053-8119issn
1095-9572pii
S1053-8119(08)00717-9journal_volume
42pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder diagnosed on the basis of motor symptoms, but that also includes cognitive and visuo-spatial deficits. Though PD is known to initially affect subcortical regions, the cortex also exhibits neuronal loss in the course of the disease as post mortem studi...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.12.043
更新日期:2011-03-15 00:00:00
abstract::Increasing evidence suggests that sleep spindles are involved in memory consolidation, but few studies have investigated the effects of learning on brain responses associated with spindles in humans. Here we used simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) during sleep to...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.03.051
更新日期:2019-07-15 00:00:00
abstract::A lack of consensus exists as to whether there are sex differences in the fMRI BOLD signal correlates of language processing in the human brain. Here, whole-brain fMRI was used to examine the neural activity of 46 adults performing one of two sets of language tasks. Conservative quantitative and qualitative criteria i...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.12.034
更新日期:2009-04-15 00:00:00
abstract::Cast shadows can be salient depth cues in three-dimensional (3D) vision. Using a motion illusion in which a ball is perceived to roll in depth on the bottom or to flow in the front plane depending on the slope of the trajectory of its cast shadow, we investigated cortical mechanisms underlying 3D vision based on cast ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.07.075
更新日期:2011-01-01 00:00:00
abstract::Quantitative assessment of the myelin water content in the brain can substantially improve our understanding of white matter diseases such as multiple sclerosis. In this study, in vivo myelin water content was estimated using T(2)* relaxation with multi-slice acquisitions in magnetic resonance imaging (MRI). The main ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.04.023
更新日期:2010-08-01 00:00:00
abstract::Two primary areas of damage have been implicated in apraxia of speech (AOS) based on the time post-stroke: (1) the left inferior frontal gyrus (IFG) in acute patients, and (2) the left anterior insula (aIns) in chronic patients. While AOS is widely characterized as a disorder in motor speech planning, little is known ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.01.015
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:Multichannel Transcranial Magnetic Stimulation (mTMS) arrays enable multiple sites to be stimulated simultaneously or sequentially under electronic control without moving the system's stimulation coils. Here, we build and characterize the performance of a novel modular 3-axis TMS coil that can be utilized as a ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117355
更新日期:2021-01-01 00:00:00
abstract::Previous studies demonstrated that brain signals encode information about specific features of simple auditory stimuli or of general aspects of natural auditory stimuli. How brain signals represent the time course of specific features in natural auditory stimuli is not well understood. In this study, we show in eight ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.04.022
更新日期:2012-07-16 00:00:00
abstract::Longitudinal neuroimaging (LNI) studies are rapidly becoming more prevalent and growing in size. Today, no standardized computational tools exist for the analysis of LNI data and widely used methods are sub-optimal for the types of data encountered in real-life studies. Linear Mixed Effects (LME) modeling, a mature ap...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.065
更新日期:2013-02-01 00:00:00
abstract::Since we do not know what future holds for us, we prepare for expected emotional events in order to deal with a pleasant or threatening environment. From an evolutionary perspective, it makes sense to be particularly prepared for the worst-case scenario. We were interested to evaluate whether this assumption is reflec...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.09.035
更新日期:2007-01-15 00:00:00
abstract::Connectivity is fundamental for understanding the nature of brain function. The intricate web of synaptic connections among neurons is critically important for shaping neural responses, representing statistical features of the sensory environment, coordinating distributed resources for brain-wide processing, and retai...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2011.08.085
更新日期:2012-08-15 00:00:00
abstract::Functional lateralization is a feature of human brain function, most apparent in the typical left-hemisphere specialization for language. A number of anatomical and imaging studies have examined whether structural asymmetries underlie this functional lateralization. We combined functional MRI (fMRI) and diffusion-weig...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.03.011
更新日期:2006-08-01 00:00:00
abstract::The brainstem is the part of the human brain that plays a pivotal role in the maintenance of many critical body functions. Due to the elevated level of cardiogenic noise, few fMRI studies have investigated the brainstem so far. Cardiac-gated echo-planar imaging with acquisition of two echoes per excitation (dual-echo ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.01.042
更新日期:2011-04-15 00:00:00
abstract::Being in control of one's emotions is not only desirable in many everyday situations but is also a great challenge in a variety of mental disorders. Successful intentional emotion regulation is related to down-regulation of amygdala activity. Training mental interventions supported by neurofeedback of one's own amygda...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2018.09.068
更新日期:2019-01-01 00:00:00
abstract::This study used arterial spin labeling (ASL) fMRI to measure brain perfusion in a group of healthy men under conditions that closely resembled customary sexual behavior. Serial perfusion measures for 30 min during two self-limited periods of partnered penis stimulation, and during post-stimulatory periods, revealed no...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.12.034
更新日期:2010-03-01 00:00:00
abstract::How do human brains integrate content with social context in communication? Recent research demonstrates that the perceived communicative embedding of perceptually identical language messages alters their cortical processing. When emotional trait-adjectives are perceived as human-generated personality feedback, event-...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.03.052
更新日期:2016-07-01 00:00:00
abstract::Despite considerable interest in enhancing, preserving, and rehabilitating working memory (WM), efforts to elicit sustained behavioral improvements have been met with limited success. Here, we paired WM training with transcranial direct current stimulation (tDCS) to the frontoparietal network over four days. Active tD...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116615
更新日期:2020-05-01 00:00:00
abstract::Many studies have investigated the temporal properties of BOLD signal responses to task performance in regions of interest, often noting significant departures from the conventionally modelled response shape, and significant variation between regions. However, these investigations are rarely extended across the whole ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.09.006
更新日期:2007-01-01 00:00:00
abstract::Instantaneous phase of brain oscillations in electroencephalography (EEG) is a measure of brain state that is relevant to neuronal processing and modulates evoked responses. However, determining phase at the time of a stimulus with standard signal processing methods is not possible due to the stimulus artifact masking...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116761
更新日期:2020-07-01 00:00:00
abstract::The sliding window correlation (SWC) analysis is a straightforward and common approach for evaluating dynamic functional connectivity. Despite the fact that sliding window analyses have been long used, there are still considerable technical issues associated with the approach. A great effort has recently been dedicate...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.02.001
更新日期:2019-04-01 00:00:00
abstract::While part of the left ventral occipito-temporal cortex (left-vOT), known as the Visual Word Form Area, plays a central role in reading, the area also responds to speech. This cross-modal activation has been explained by three competing hypotheses. Firstly, speech is converted to orthographic representations that acti...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.11.014
更新日期:2019-02-01 00:00:00
abstract::There is increasing interest in exploring the use of functional MRI neurofeedback (fMRI-NF) as a therapeutic technique for a range of neurological conditions such as stroke and Parkinson's disease (PD). One main therapeutic potential of fMRI-NF is to enhance volitional control of damaged or dysfunctional neural nodes ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.09.007
更新日期:2019-01-01 00:00:00
abstract::Interactions between the posterior parietal cortex and the early visual cortex have been proposed to play a central role in the binding of visual features into coherent objects. Here we investigated the importance of these interactions by contrasting the time windows at which the early visual cortex (V1/V2) and the an...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.08.089
更新日期:2012-01-16 00:00:00
abstract::Recently, deriving candidate endophenotypes from brain imaging data has become a valuable approach to study genetic influences on schizophrenia (SZ), whose pathophysiology remains unclear. In this work we utilized a multivariate approach, parallel independent component analysis, to identify genomic risk components ass...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.03.022
更新日期:2012-07-16 00:00:00
abstract::In the early days of BOLD fMRI, the acquisition of T(2)(*) weighted data was greatly facilitated by rapid scan techniques such as EPI. The latter, however, was only available on a few MRI systems that were equipped with specialized hardware that allowed rapid switching of the imaging gradients. For this reason, soon a...
journal_title:NeuroImage
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.neuroimage.2012.01.017
更新日期:2012-08-15 00:00:00
abstract::Modern neuroimaging technologies afford a non-invasive view into the functions of the human brain with great spatial (fMRI) and temporal resolution (EEG). However, common signal analytic methods require averaging over many trials, which limits the potential for practical application of these technologies. In this pape...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.03.031
更新日期:2008-08-15 00:00:00
abstract::We describe the construction of a digital brain atlas composed of data from manually delineated MRI data. A total of 56 structures were labeled in MRI of 40 healthy, normal volunteers. This labeling was performed according to a set of protocols developed for this project. Pairs of raters were assigned to each structur...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.09.031
更新日期:2008-02-01 00:00:00
abstract::Adolescence is increasingly viewed as a sensitive period in the development of substance use disorders (SUDs). Neurodevelopmental 'dual-risk' theories suggest adolescent vulnerability to problematic substance use is driven by an overactive reward drive mediated by the striatum, and poor cognitive control mediated by t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.116476
更新日期:2020-04-01 00:00:00
abstract::Blinks and saccades, both ubiquitous in natural viewing conditions, cause rapid changes of visual inputs that are hardly consciously perceived. The neural dynamics in early visual areas of the human brain underlying this remarkable visual stability are still incompletely understood. We used electrocorticography (ECoG)...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2021.117788
更新日期:2021-01-24 00:00:00
abstract::We evaluated the cholinergic mechanism underlying focal cortical vascular response to neuronal activation, using positron emission tomography for use on animals to measure cerebral blood flow and glucose metabolism activation upon vibrotactile stimulation in cats. Bromopyruvate, which blocks acetylcholine synthesis th...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1996.0021
更新日期:1996-06-01 00:00:00